当前位置： SCI文献检索 > JOURNAL OF HEPATOLOGY期刊下所有文献 > Vinyl chloride and the liver.

Vinyl chloride and the liver.

Abstract：

:Vinyl chloride monomer is a known cause of angiosarcoma of the liver. It also has other toxic effects on the liver, and it has recently been suggested that exposure to vinyl chloride also causes hepatocellular carcinoma. However, the data on which this conclusion is based is incomplete. There is inadequate ascertainment of unequivocal diagnoses. In the largest studies lack of data meant that confounding diseases such as viral hepatitis or alcoholic liver disease could not be assessed. At best, the increase in risk is minimal, based on more than 22,000 exposed workers and more than 640,000 person years of observation. However, based on the available data the hypothesis that vinyl chloride causes or contributes to the development of hepatocellular carcinoma remains unproven.

journal_name

J Hepatol

journal_title

Journal of hepatology

authors

Sherman M

doi

10.1016/j.jhep.2009.09.012

subject

Has Abstract

pub_date

2009-12-01 00:00:00

pages

1074-81

issue

6

eissn

0168-8278

issn

1600-0641

pii

S0168-8278(09)00634-5

journal_volume

51

pub_type

杂志文章,评审

相关文献

JOURNAL OF HEPATOLOGY文献大全
  • SARS-CoV-2 infection of the liver directly contributes to hepatic impairment in patients with COVID-19.

    abstract：Background & Aims:Liver enzyme abnormalities are common in patients with coronavirus disease 2019 (COVID-19). Whether or not severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can lead to liver damage per se remains unknown. Herein, we reported the clinical characteristics and liver pathological man...

    journal_title：Journal of hepatology

    pub_type： 杂志文章

    doi：10.1016/j.jhep.2020.05.002

    authors： Wang Y,Liu S,Liu H,Li W,Lin F,Jiang L,Li X,Xu P,Zhang L,Zhao L,Cao Y,Kang J,Yang J,Li L,Liu X,Li Y,Nie R,Mu J,Lu F,Zhao S,Lu J,Zhao J

    更新日期：2020-10-01 00:00:00

  • Generation of a monoclonal human single chain antibody fragment to hepatic stellate cells--a potential mechanism for targeting liver anti-fibrotic therapeutics.

    abstract：BACKGROUND/AIMS:Hepatic stellate cells are pivotal to fibrogenesis in the liver and many potential anti-fibrotic therapeutics are required to act on targets within hepatic stellate cells. The aim of this study was to generate a human antibody fragment to hepatic stellate cells. METHODS:Phage display was used to genera...

    journal_title：Journal of hepatology

    pub_type： 杂志文章

    doi：10.1016/j.jhep.2005.01.028

    authors： Elrick LJ,Leel V,Blaylock MG,Duncan L,Drever MR,Strachan G,Charlton KA,Koruth M,Porter AJ,Wright MC

    更新日期：2005-06-01 00:00:00

  • Expression of HLA antigens and T cell infiltrates in chronic viral hepatitis. A comparison of biopsy and fine-needle aspiration findings.

    abstract：:To evaluate the expression of hepatocyte HLA Class I and II antigens and the infiltration of CD8-positive lymphocytes in patients with chronic hepatitis, cells obtained by the technique of fine-needle aspiration were compared with those obtained by percutaneous liver biopsy. In general, correlation between cytological...

    journal_title：Journal of hepatology

    pub_type： 杂志文章

    doi：10.1016/0168-8278(91)90937-7

    authors： Krawitt EL,Zannier A,Chossegros P,Gerard F,Chevallier M,Mutin M,Trepo C,Touraine JL

    更新日期：1991-03-01 00:00:00

  • Production of abnormal prothrombin (des-gamma-carboxy prothrombin) by hepatocellular carcinoma. A clinical and experimental study.

    abstract：:We measured plasma abnormal prothrombin (des-gamma-carboxy prothrombin; DCP) levels in normal subjects and in patients with hepatocellular carcinoma and other various diseases using the enzyme-linked immunosorbent assay developed by Motohara et al. (Pediatr Res 1985; 19: 354-357). Fifty-eight percent of 52 patients wi...

    journal_title：Journal of hepatology

    pub_type： 杂志文章

    doi：10.1016/s0168-8278(87)80546-9

    authors： Okuda H,Obata H,Nakanishi T,Furukawa R,Hashimoto E

    更新日期：1987-06-01 00:00:00

  • Twenty-one percent partial hepatectomy. In vivo rat model for the study of liver regeneration.

    abstract：:We describe a new model of submaximal stimulation of liver regeneration in the rat. Removal of the right lateral lobes in the rat produced a 21% hepatectomy. The measurement accuracy of the incorporation rate of [14C]thymidine into DNA 24 h after 21% hepatectomy (n = 32) was less than that after the standard 34% hepat...

    journal_title：Journal of hepatology

    pub_type： 杂志文章

    doi：10.1016/0168-8278(91)90833-w

    authors： Baruch Y,Frith LO,Kirsch RE

    更新日期：1991-05-01 00:00:00

  • Early tacrolimus exposure after liver transplantation: relationship with moderate/severe acute rejection and long-term outcome.

    abstract：BACKGROUND & AIMS:Liver transplant (LT) patients might be overimmunosuppressed as recommendations for tacrolimus trough concentrations (TC) within 4-6 weeks after liver transplantation are set too high (10-15 ng/ml). Early tacrolimus exposure was evaluated in relation to acute rejection and long-term outcomes. METHODS...

    journal_title：Journal of hepatology

    pub_type： 杂志文章

    doi：10.1016/j.jhep.2012.09.019

    authors： Rodríguez-Perálvarez M,Germani G,Papastergiou V,Tsochatzis E,Thalassinos E,Luong TV,Rolando N,Dhillon AP,Patch D,O'Beirne J,Thorburn D,Burroughs AK

    更新日期：2013-02-01 00:00:00

  • Effects of propranolol and sucralfate on ethanol-induced gastric mucosal damage in chronic portal hypertensive rats.

    abstract：:In a rat model of chronic portal hypertension we studied ethanol-induced gastric mucosal damage and the effects of pretreatment by propranolol and sucralfate. Susceptibility to ethanol was increased in chronic portal hypertensive rats compared with sham-operated rats (55 +/- 8% vs. 25 +/- 4%). Both acute pretreatment ...

    journal_title：Journal of hepatology

    pub_type： 杂志文章

    doi：10.1016/s0168-8278(87)80568-8

    authors： Geoffroy P,Duchateau A,Thiéfin G,Zeitoun P

    更新日期：1987-10-01 00:00:00

  • Impaired ketogenesis is a major mechanism for disturbed hepatic fatty acid metabolism in rats with long-term cholestasis and after relief of biliary obstruction.

    abstract：BACKGROUND/AIMS:Rats with long-term cholestasis have reduced ketosis of unknown origin. METHODS:Fatty acid metabolism was studied in starved rats with biliary obstruction for 4 weeks (bile duct ligated rats = BDL rats), and 3, 7, 14, 28 and 84 days after reversal of biliary obstruction by Roux-en-Y anastomosis (RY rat...

    journal_title：Journal of hepatology

    pub_type： 杂志文章

    doi：10.1016/s0168-8278(02)00248-9

    authors： Lang C,Berardi S,Schäfer M,Serra D,Hegardt FG,Krähenbühl L,Krähenbühl S

    更新日期：2002-11-01 00:00:00

  • Transplantation of the liver in adults and children with fulminant hepatic failure.

    abstract：:Fulminant hepatic failure has a high mortality rate despite intensive medical treatment. Urgent hepatic transplantation was considered over a 3 year period in 26 (36%) of 73 patients with the worst prognostic features of fulminant hepatic failure. The criteria for patient selection were based on the duration of advanc...

    journal_title：Journal of hepatology

    pub_type： 杂志文章

    doi：10.1016/s0168-8278(88)80475-6

    authors： Vickers C,Neuberger J,Buckels J,McMaster P,Elias E

    更新日期：1988-10-01 00:00:00

  • Inhibition of receptor-interacting protein kinase 1 improves experimental non-alcoholic fatty liver disease.

    abstract：BACKGROUND & AIMS:In non-alcoholic fatty liver disease (NAFLD), hepatocytes can undergo necroptosis: a regulated form of necrotic cell death mediated by the receptor-interacting protein kinase (RIPK) 1. Herein, we assessed the potential for RIPK1 and its downstream effector mixed lineage kinase domain-like protein (MLK...

    journal_title：Journal of hepatology

    pub_type： 杂志文章

    doi：10.1016/j.jhep.2019.11.008

    authors： Majdi A,Aoudjehane L,Ratziu V,Islam T,Afonso MB,Conti F,Mestiri T,Lagouge M,Foufelle F,Ballenghien F,Ledent T,Moldes M,Cadoret A,Fouassier L,Delaunay JL,Aït-Slimane T,Courtois G,Fève B,Scatton O,Prip-Buus C,Rodrig

    更新日期：2020-04-01 00:00:00

  • Elevated levels of circulating osteopontin are associated with a poor survival after resection of cholangiocarcinoma.

    abstract：BACKGROUND & AIMS:Cholangiocarcinoma (CCA) represents a primary hepatic malignancy with incidence and mortality rising globally. Surgical treatment has remained the only potentially curative treatment option, but it is still unclear which patients benefit most from extended liver surgery, highlighting the need for new ...

    journal_title：Journal of hepatology

    pub_type： 杂志文章

    doi：10.1016/j.jhep.2017.06.020

    authors： Loosen SH,Roderburg C,Kauertz KL,Pombeiro I,Leyh C,Benz F,Vucur M,Longerich T,Koch A,Braunschweig T,Ulmer TF,Heidenhain C,Tacke F,Binnebösel M,Schmeding M,Trautwein C,Neumann UP,Luedde T

    更新日期：2017-10-01 00:00:00

  • Platelet basal cytosolic calcium: the influence of plasma factors in cirrhosis.

    abstract：BACKGROUND:Platelet cytosolic calcium is necessary for normal platelet function, and may reflect intracellular signalling in vascular smooth muscle cells. METHODS:The cytosolic calcium of platelets from patients with cirrhosis and control subjects was measured in contact with plasma from either source, using FURA 2AM....

    journal_title：Journal of hepatology

    pub_type： 杂志文章

    doi：10.1016/s0168-8278(96)80117-6

    authors： Forrest EH,Dillon JF,Campbell TJ,Newsome PN,Hayes PC

    更新日期：1996-09-01 00:00:00

  • Machine perfusion in liver transplantation as a tool to prevent non-anastomotic biliary strictures: Rationale, current evidence and future directions.

    abstract：:The high incidence of non-anastomotic biliary strictures (NAS) after transplantation of livers from extended criteria donors is currently a major barrier to widespread use of these organs. This review provides an update on the most recent advances in the understanding of the etiology of NAS. These new insights give re...

    journal_title：Journal of hepatology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jhep.2015.03.008

    authors： Weeder PD,van Rijn R,Porte RJ

    更新日期：2015-07-01 00:00:00

  • The relationship of endoscopy, portal Doppler ultrasound flowmetry, and clinical and biochemical tests in cirrhosis.

    abstract：:The relationship of the endoscopic aspect of esophageal varices, portal quantitative Doppler ultrasound parameters and clinical and biochemical findings was assessed in 149 patients with cirrhosis stratified according to the presence of esophageal varices (n = 115) and the absence of previous bleeding (n = 96). In thi...

    journal_title：Journal of hepatology

    pub_type： 杂志文章

    doi：10.1016/s0168-8278(05)80461-1

    authors： Siringo S,Bolondi L,Gaiani S,Sofia S,Di Febo G,Zironi G,Rigamonti A,Miglioli M,Cavalli G,Barbara L

    更新日期：1994-01-01 00:00:00

  • Global liver disease burdens and research trends: Analysis from a Chinese perspective.

    abstract：:Liver diseases affect millions of people worldwide. In most developed countries, the incidence of viral hepatitis is waning as a result of modern advances in disease prevention, diagnosis, and therapies. Expanded programmes for systematic immunisation against hepatitis B virus have also significantly brought down the ...

    journal_title：Journal of hepatology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jhep.2019.03.004

    authors： Xiao J,Wang F,Wong NK,He J,Zhang R,Sun R,Xu Y,Liu Y,Li W,Koike K,He W,You H,Miao Y,Liu X,Meng M,Gao B,Wang H,Li C

    更新日期：2019-07-01 00:00:00

  • An in situ molecular signature to predict early recurrence in hepatitis B virus-related hepatocellular carcinoma.

    abstract：BACKGROUND & AIMS:To develop an in situ molecular signature to predict postsurgical recurrence in hepatocellular carcinoma (HCC) patients. METHODS:Immunohistochemistry was performed using tissue microarrays containing both tumoral and peri-tumoral regions of the advancing tumor edge from 336 HCC patients (289 were pos...

    journal_title：Journal of hepatology

    pub_type： 杂志文章

    doi：10.1016/j.jhep.2012.03.027

    authors： Xu J,Ding T,He Q,Yu XJ,Wu WC,Jia WH,Yun JP,Zhang Y,Shi M,Shao CK,Pan WD,Yin XY,Min J,Zhuang SM,Zheng L

    更新日期：2012-08-01 00:00:00

  • Cellular immune response to hepatitis B virus antigens. An overview.

    abstract：:It has been suggested that the cellular immune response to HBV antigens is responsible for hepatocellular injury in acute and chronic hepatitis B. However, definitive immunological studies have so far been hampered by the lack of appropriate model systems to study HBV antigen-specific T cells. The availability of high...

    journal_title：Journal of hepatology

    pub_type： 杂志文章,评审

    doi：10.1016/s0168-8278(88)80503-8

    authors： Ferrari C,Penna A,DegliAntoni A,Fiaccadori F

    更新日期：1988-08-01 00:00:00

  • Gut-liver immunity.

    abstract：:The liver contributes to immune surveillance against pathogens entering via the gut and is itself influenced by alterations in mucosal immune responses and the microbiome. Mucosal immunity is also implicated in autoimmune liver diseases that associate with inflammatory bowel disease (IBD), and in steatohepatitis where...

    journal_title：Journal of hepatology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jhep.2015.12.002

    authors： Trivedi PJ,Adams DH

    更新日期：2016-05-01 00:00:00

  • Non-radioactive hybridization with hepatitis C virus-specific probes created during polymerase chain reaction: a fast and simple procedure to verify hepatitis C virus infection.

    abstract：:All routinely available assays to detect hepatitis C virus (HCV) infection are based on the specific reaction of serum antibodies to corresponding viral antigens. The only method to detect viral nucleic acids in serum or liver is the enzymatic amplification of reversely transcribed HCV-RNA by polymerase chain reaction...

    journal_title：Journal of hepatology

    pub_type： 杂志文章

    doi：10.1016/0168-8278(92)90074-y

    authors： Geiger CP,Caselmann WH

    更新日期：1992-07-01 00:00:00

  • Risk of chronic kidney disease in patients with non-alcoholic fatty liver disease: is there a link?

    abstract：:Non-alcoholic fatty liver disease (NAFLD) has emerged as a growing public health problem worldwide. Increasing recognition of the importance of NAFLD and its association with the features of the metabolic syndrome has stimulated an interest in its putative role in the development and progression of chronic kidney dise...

    journal_title：Journal of hepatology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jhep.2010.11.007

    authors： Targher G,Chonchol M,Zoppini G,Abaterusso C,Bonora E

    更新日期：2011-05-01 00:00:00

  • Sustained virologic response of 100% in HCV genotype 1b patients with cirrhosis receiving ombitasvir/paritaprevir/r and dasabuvir for 12weeks.

    abstract：BACKGROUND & AIMS:Patients with chronic hepatitis C virus (HCV) infection and cirrhosis have a higher risk for liver-related complications and have historically been more difficult to cure than patients without cirrhosis. We evaluated the safety and efficacy of ombitasvir/paritaprevir/ritonavir and dasabuvir, without r...

    journal_title：Journal of hepatology

    pub_type： 临床试验,杂志文章

    doi：10.1016/j.jhep.2015.10.005

    authors： Feld JJ,Moreno C,Trinh R,Tam E,Bourgeois S,Horsmans Y,Elkhashab M,Bernstein DE,Younes Z,Reindollar RW,Larsen L,Fu B,Howieson K,Polepally AR,Pangerl A,Shulman NS,Poordad F

    更新日期：2016-02-01 00:00:00

  • Prospects for xenotransplantation of the liver.

    abstract：:Because of the tremendous success of clinical transplantation of the liver and other organs in the last three decades, the demand for organs for transplantation has risen sharply and there is now a substantial shortage. The utilization of organs from other species, xenotransplantation, is increasingly viewed as a pote...

    journal_title：Journal of hepatology

    pub_type： 杂志文章,评审

    doi：10.1016/s0168-8278(96)80082-1

    authors： Harland RC,Platt JL

    更新日期：1996-08-01 00:00:00

  • Human hepatic stellate cells secrete adrenomedullin: potential autocrine factor in the regulation of cell contractility.

    abstract：BACKGROUND/AIMS:Hepatic stellate cells (HSCs) are perisinusoidal pericytes which have receptors for vasoactive factors, such as endothelin-1, which can regulate cell contractility in an autocrine manner. It is unknown whether human HSCs have receptors for and are able to synthesize the vasodilator peptide adrenomedulli...

    journal_title：Journal of hepatology

    pub_type： 杂志文章

    doi：10.1016/s0168-8278(00)00016-7

    authors： Görbig MN,Ginès P,Bataller R,Nicolás JM,Garcia-Ramallo E,Cejudo P,Sancho-Bru P,Jiménez W,Arroyo V,Rodés J

    更新日期：2001-02-01 00:00:00

  • Phenotypic and functional analyses show stem cell-derived hepatocyte-like cells better mimic fetal rather than adult hepatocytes.

    abstract：BACKGROUND & AIMS:Hepatocyte-like cells (HLCs), differentiated from pluripotent stem cells by the use of soluble factors, can model human liver function and toxicity. However, at present HLC maturity and whether any deficit represents a true fetal state or aberrant differentiation is unclear and compounded by compariso...

    journal_title：Journal of hepatology

    pub_type： 杂志文章

    doi：10.1016/j.jhep.2014.10.016

    authors： Baxter M,Withey S,Harrison S,Segeritz CP,Zhang F,Atkinson-Dell R,Rowe C,Gerrard DT,Sison-Young R,Jenkins R,Henry J,Berry AA,Mohamet L,Best M,Fenwick SW,Malik H,Kitteringham NR,Goldring CE,Piper Hanley K,Vallier L,

    更新日期：2015-03-01 00:00:00

  • Normal pharmacologically-induced, but decreased regenerative liver growth in interleukin-6-deficient (IL-6(-/-)) mice.

    abstract：BACKGROUND/AIMS:In the absence of liver damage, rapid liver growth can be induced pharmacologically by so-called primary liver growth promoters. The importance of the acute-phase cytokines interleukin-6 and tumor necrosis factor-alpha for the actions of these compounds is not clear. This study aimed to investigate the ...

    journal_title：Journal of hepatology

    pub_type： 杂志文章

    doi：10.1016/s0168-8278(00)80130-0

    authors： Wallenius V,Wallenius K,Jansson JO

    更新日期：2000-12-01 00:00:00

  • HBe antibody unrelated to 'e minus' hepatitis B virus variant infection in patients with chronic type D hepatitis.

    abstract：:The presence of HBV-DNA sequences was evaluated in DNA extracted from serum samples, peripheral blood lymphocytes and liver biopsy specimens of five HBsAg/anti-HBe-positive carriers with chronic HDV infection. DNAs were tested by polymerase chain reaction (PCR) amplification technique using two pairs of oligonucleotid...

    journal_title：Journal of hepatology

    pub_type： 杂志文章

    doi：10.1016/0168-8278(91)90032-7

    authors： Raimondo G,Rodinò G,Brancatelli S,Sardo MA,Campo S,Smedile V,Villari D,Pernice M,Longo G,Squadrito G

    更新日期：1991-01-01 00:00:00

  • Staging chronic hepatitis C in seven categories using fibrosis biomarker (FibroTest™) and transient elastography (FibroScan®).

    abstract：BACKGROUND & AIMS:FibroTest™ (FT) and Transient Elastography (TE) have been validated as non-invasive markers of METAVIR fibrosis stages from F0 to F4 using biopsy, and as prognostic markers of liver related mortality in patients with chronic hepatitis C. The aim was to extend the validation of FT and TE as markers of ...

    journal_title：Journal of hepatology

    pub_type： 杂志文章

    doi：10.1016/j.jhep.2013.11.016

    authors： Poynard T,Vergniol J,Ngo Y,Foucher J,Munteanu M,Merrouche W,Colombo M,Thibault V,Schiff E,Brass CA,Albrecht JK,Rudler M,Deckmyn O,Lebray P,Thabut D,Ratziu V,de Ledinghen V,FibroFrance Study Group.,Epic3 Study Group.,

    更新日期：2014-04-01 00:00:00

  • β7-Integrin and MAdCAM-1 play opposing roles during the development of non-alcoholic steatohepatitis.

    abstract：BACKGROUND & AIMS:Non-alcoholic steatohepatitis (NASH) is a leading cause of chronic liver disease in Western countries. It is unclear how infiltrating leukocytes affect NASH-development. Our study aims to investigate the role of the homing/receptor, pair mucosal addressin cell adhesion molecule-1 (MAdCAM-1)/β7-Integri...

    journal_title：Journal of hepatology

    pub_type： 杂志文章

    doi：10.1016/j.jhep.2017.02.001

    authors： Drescher HK,Schippers A,Clahsen T,Sahin H,Noels H,Hornef M,Wagner N,Trautwein C,Streetz KL,Kroy DC

    更新日期：2017-06-01 00:00:00

  • Cyclooxygenase-1 inhibition corrects endothelial dysfunction in cirrhotic rat livers.

    abstract：BACKGROUND/AIMS:Cirrhotic livers exhibit endothelial dysfunction that contributes to the increased hepatic vascular resistance. The present study evaluates the role of cyclooxygenase (COX)-derived prostanoids, implicated in the pathogenesis of endothelial dysfunction in other settings, in the pathogenesis of endothelia...

    journal_title：Journal of hepatology

    pub_type： 杂志文章

    doi：10.1016/s0168-8278(03)00347-7

    authors： Graupera M,García-Pagán JC,Parés M,Abraldes JG,Roselló J,Bosch J,Rodés J

    更新日期：2003-10-01 00:00:00

  • Treatment of chronic hepatitis B with interferon alpha-2b and interleukin-2.

    abstract：:A total of 37 patients with histologically confirmed chronic viral hepatitis B and presence of HBV-DNA and HBsAg in the serum were treated in a randomized, prospectively controlled multicenter trial either with recombinant IFN alpha-2b alone or a combination of IFN alpha-2b and recombinant IL-2. Twenty-two patients fr...

    journal_title：Journal of hepatology

    pub_type： 临床试验,杂志文章,多中心研究,随机对照试验

    doi：10.1016/s0168-8278(05)80424-6

    authors： Bruch HR,Korn A,Klein H,Markus R,Malmus K,Baumgarten R,Müller R

    更新日期：1993-01-01 00:00:00