Abstract：
:Home international normalized ratio (INR) monitors are being increasingly used for monitoring the adequacy of anticoagulation in children on long-term warfarin. Their safety and effectiveness in the home setting has not been fully established. The purpose of this study was to explore the safety and effectiveness of home INR monitoring service in managing anticoagulation in children with congenital heart disease. At the Pediatric Cardiology Regional Referral Center, we studied records of 41 children on warfarin and assessed the control of anticoagulation and frequency of adverse reactions over a 1-year period. User satisfaction was assessed by means of telephone interviews. The study found that the therapeutic INR range was maintained for over 57% of the total study period. There were no reported instances of major or minor hemorrhages. On six occasions, subtherapeutic INR levels necessitated hospitalization for heparinization. Mitral valve replacement was significantly associated with poor control (p < 0.05). User satisfaction was high for all aspects of the service evaluated. The hospital-assisted home INR monitoring service is a safe and effective means of managing anticoagulation in children. In addition, it ensures good compliance and a high level of user satisfaction.
journal_name
Pediatr Cardioljournal_title
Pediatric cardiologyauthors
Bhat D,Upponi A,Rakecha A,Thomson Jdoi
10.1007/s00246-009-9535-xsubject
Has Abstractpub_date
2010-01-01 00:00:00pages
18-21issue
1eissn
0172-0643issn
1432-1971journal_volume
31pub_type
杂志文章abstract：:Numerous RNA-binding proteins (RBPs) are expressed in the heart, and mutations in several RBPs have been implicated in cardiovascular disease through genetic associations, animal modeling, and mechanistic studies. However, the functions of many more cardiac RBPs, and their relevance to disease states, remain to be elu...
journal_title：Pediatric cardiology
pub_type： 杂志文章,评审
doi：10.1007/s00246-019-02180-6
更新日期：2019-10-01 00:00:00
abstract：:We report a unique case of tricuspid and pulmonary atresia with idiopathic progressive ductus arteriosus restriction in utero. Diligent predelivery planning and a controlled delivery environment led to a favorable outcome. ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-012-0391-8
更新日期：2013-08-01 00:00:00
abstract：:The proximal course of an anomalously arising coronary artery is a decisive factor in the surgical approach for tetralogy of Fallot (TOF). Studies have shown that echocardiography provides a good anatomic definition of the ostium and proximal epicardial course of coronary arteries [1, 2]. This report describes a case ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-012-0444-z
更新日期：2013-01-01 00:00:00
abstract：:Identification of heart transplant recipients at highest risk for a poor outcome could lead to improved posttransplantation survival. A chart review of primary heart transplantations from 1993 to 2006 was performed. Analysis was performed to evaluate the risk of graft loss for those with a transplantation age less tha...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-011-0077-7
更新日期：2012-01-01 00:00:00
abstract：:The American Academy of Pediatrics (AAP) recommends that any child diagnosed with hypertension have an echocardiogram to evaluate for the presence of left-ventricular (LV) hypertrophy (LVH) and advocates that LVH is an indication to initiate or intensify antihypertensive therapy. However, there is no consensus on the ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-013-0829-7
更新日期：2014-04-01 00:00:00
abstract：:Inferior sinus venosus defects (SVDs) are rare imperfections located in the inferior portion of the atrial septum, leading to an overriding inferior vena cava (IVC) and an interatrial connection. These defects have increased risk of anomalous pulmonary venous return (PAPVR) and often are confused with secundum atrial ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-012-0449-7
更新日期：2013-02-01 00:00:00
abstract：:Electrocardiograms (heart rate, QRS voltage, QRS axis in the frontal plane. Q-Tc interval) echocardiograms [left ventricular fractional shortening (LVFS); preejection period (PEP); PEP/left ventricular ejection time (PEP/LVET) ratio; end-diastolic left ventricular free wall and interventricular septum thickness; prese...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF02238495
更新日期：1991-01-01 00:00:00
abstract：:This review discusses the historical aspects, current state of the art, and potential future advances in the areas of nomenclature and databases for congenital heart disease. Five areas will be reviewed: (1) common language = nomenclature, (2) mechanism of data collection (database or registry) with an established uni...
journal_title：Pediatric cardiology
pub_type： 杂志文章,评审
doi：10.1007/s00246-006-1447-4
更新日期：2007-03-01 00:00:00
abstract：:Interruption of the aortic arch and hypoplastic left heart syndrome in the same patient is exceptional. In the combined collections of the Registry of Cardiovascular Disease (St. Paul, Minnesota, U.S.A.) and the Registry of Congenital Heart Defects of the Rijksuniversiteit Gent (Gent, Belgium) three specimens were fou...
journal_title：Pediatric cardiology
pub_type： 杂志文章,评审
doi：10.1007/BF00798068
更新日期：1995-11-01 00:00:00
abstract：:At the University of California Davis Medical Center, a screening fetal ultrasound examination (level I or II) incorporates a comprehensive segmental evaluation of the fetal heart. This study evaluated the reliability of the fetal ultrasound exam in the detection of abnormal heart anatomy. Our retrospective study revi...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-001-0073-4
更新日期：2002-11-01 00:00:00
abstract：:The commonly used Darling classification for total anomalous pulmonary venous connection (TAPVC) consists of supracardiac, cardiac, infracardiac, and mixed types (Craig et al., Lab Invest 6:44-64, 1967). In supracardiac TAPVC, the common pulmonary vein drains superiorly into the left innominate vein, the superior vena...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-009-9509-z
更新日期：2009-10-01 00:00:00
abstract：:A 6-year-old girl with evidence of a parahisian accessory pathway on a baseline electrocardiogram underwent successful catheter ablation using magnetic navigation. Magnetic remote controlled ablation eliminated the parahisian pathway with the first radiofrequency application. A second anterolaterally located concealed...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-012-0540-0
更新日期：2013-03-01 00:00:00
abstract：:Warfarin dosing is challenging due to a multitude of factors affecting its pharmacokinetics (PK) and pharmacodynamics (PD). A novel personalised dosing algorithm predicated on a warfarin PK/PD model and incorporating CYP2C9 and VKORC1 genotype information has been developed for children. The present prospective, obser...
journal_title：Pediatric cardiology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00246-019-02215-y
更新日期：2019-12-01 00:00:00
abstract：:The treatment of recurrent supraventricular tachycardia in a 3-week-old infant is described. Multiple doses of adenosine were used successfully to convert the dysrhythmia, without adverse effects or apparent tachyphylaxis. ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s002469900222
更新日期：1997-11-01 00:00:00
abstract：:An aneurysm of the fossa ovalis was identified at autopsy in 17 infants. In each case the aneurysm of the fossa ovalis was considered to have resulted from excessive elevation of pressure in that atrium contralateral to the side into which the aneurysm bulged. The aneurysms were divided into two types: intrinsic (thre...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF02282740
更新日期：1985-01-01 00:00:00
abstract：:Paroxysmal non-reentrant supraventricular tachycardia due to double ventricular response through antegrade dual atrioventricular nodal pathways by a single atrial excitation has been reported in limited adult cases but not in pediatric patients with structurally normal hearts or with congenital heart defects. We repor...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-012-0326-4
更新日期：2013-03-01 00:00:00
abstract：:Different devices have been used for percutaneous closure of ventricular septal defects (VSDs). Over the past 6 months, we have used the Amplatzer duct occluder for VSDs associated with tunnel-shaped aneurysm in three patients here at our institution. Due to the anatomic resemblance between such VSDs and the duct occl...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-007-9092-0
更新日期：2008-03-01 00:00:00
abstract：:The objective of this study was to evaluate the incidence of pre-existing catheterization left pulmonary artery (LPA) gradients and correlation of these gradients with later LPA stenosis after successful patent ductus arteriosus (PDA) occlusion. We performed a single-center review of 130 patients with PDA closure from...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-009-9448-8
更新日期：2009-10-01 00:00:00
abstract：:The most common modes of medical education for congenital heart disease (CHD) rely heavily on 2-dimensional imaging. Three-dimensional (3D) printing technology allows for the creation of physical cardiac models that can be used for teaching trainees. 3D printed cardiac models were created for the following lesions: pu...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-019-02146-8
更新日期：2019-08-01 00:00:00
abstract：:The spectrum of cardiac anomalies in trisomy 18 typically includes septal defects and polyvalvular disease and only rarely complex malformations. We report the first case of trisomy 18 with truncus arteriosus type II. ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF00796330
更新日期：1994-05-01 00:00:00
abstract：:Information and communication technology has been widely applied to various fields, including clinical medicine. We report here a telediagnosis system using ultrasound image transmission. The effect of telediagnosis, using a medical link between local maternity hospitals and our children's medical center, was verified...
journal_title：Pediatric cardiology
pub_type： 杂志文章,多中心研究
doi：10.1007/s00246-013-0834-x
更新日期：2014-04-01 00:00:00
abstract：:Myocardial blood flow (MBF) was investigated in children (14.2 +/- 5.01 years) with "resolved" coronary involvement after the onset of Kawasaki disease and angiographically normal epicardial coronary arteries. Ten asymptomatic children with a history of Kawasaki disease had electrocardiography, echocardiography, and p...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-003-0472-9
更新日期：2004-03-01 00:00:00
abstract：:We sought to characterize the shifting epidemiology and resource utilization of Lyme disease and associated carditis in US children's hospitals. We hypothesized that the Lyme carditis burden has increased and that hospitalizations for Lyme carditis are costlier than those for Lyme disease without carditis. The PHIS da...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-019-02250-9
更新日期：2020-02-01 00:00:00
abstract：:The genetic basis of congenital heart disease remains unknown in most of the cases. Recently, a novel mouse model shed new light on the role of CCN1/CYR61, a matricellular regulatory factor, in cardiac morphogenesis. In a candidate gene approach, we analyzed a cohort of 143 patients with atrial septal defects (ASD) by...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-014-1001-8
更新日期：2015-02-01 00:00:00
abstract：:To examine factors associated with low high-density lipoprotein cholesterol (HDL-C) levels among middle school children. HDL-C levels were the primary outcome of interest. A total of 1,104 middle-school children (mean age 11.6 years, 51.2% female) were included in this analysis, of whom 177 (16%) had an HDL-C level ≤4...
journal_title：Pediatric cardiology
pub_type： 杂志文章,多中心研究
doi：10.1007/s00246-013-0814-1
更新日期：2014-03-01 00:00:00
abstract：:Surgical closure of the secundum type of atrial septal defect (ASD) in childhood leads to excellent survival. However, relevant morbidity has been reported. Transcatheter closure of these defects has now become an alternative approach. To compare the results of the two different interventions, reliable data are needed...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-005-0838-2
更新日期：2005-09-01 00:00:00
abstract：:We present a case of congenital pulmonary systemic collateral vein associated with truncus arteriosus. Pulmonary systemic collateral vein with nonobstructed left atrial egress is different from those with obstructed left atrial egress in that it is functionally redundant. Including this case, 8 patients among 33 repor...
journal_title：Pediatric cardiology
pub_type： 杂志文章,评审
doi：10.1007/s00246-002-0439-2
更新日期：2004-01-01 00:00:00
abstract：:We measured the coronary flow reserve in a 13-year-old girl with the rare anomaly of an absent left circumflex coronary artery. Although the coronary flow volume of the right coronary artery was at the same level as that of the left anterior descending coronary artery, the coronary flow reserve of the patient's right ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s002460010188
更新日期：2001-03-01 00:00:00
abstract：:Left atrial tumor, diagnosed as myxoma at first investigation, was later demonstrated to be a malignant fibrosarcoma with myxoid change. Myxoma should be diagnosed and managed carefully because of its wide range of histopathologic features. ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s002460010218
更新日期：2001-05-01 00:00:00
abstract：:Ruptured sinus Valsalva aneurysm (SVA) in a patient with tetralogy of Fallot is a very rare cardiac complication. This report describes the case of a 10-year-old Hispanic girl who presented to her cardiologist for a routine transthoracic echocardiography (TTE), which showed a ruptured sinus of Valsalva, with left-to-r...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-012-0457-7
更新日期：2013-01-01 00:00:00
