Abstract:
:Duodeno-pancreatic neuroendocrine tumours (DP-ETs) are increasingly diagnosed today due to the widespread use of modern imaging methods. Duodeno-pancreatic endocrine tumours should be treated by radical surgical resection, which offers a high chance for cure when the disease is localized. A high index of suspicion is required in these patients for the presence of a multiple endocrine neoplasia type syndrome. We present four patients with DP-ET surgically treated at our department between 2000 and 2004. Histological/immunohistochemical diagnosis was somatostatin-producing tumour in the first patient, oncocytic endocrine tumour positive for neurone-specific enolase and focally for chromogranin in the second patient, glucagonoma and pancreatic polypeptide-producing endocrine pancreatic tumour in the third patient, and gastrin, somatostatin, calcitonin, insulin and adrenocorticotropic hormone (ACTH)-producing tumour in the fourth. The second patient died 6.5 years following surgery due to disseminated disease.
journal_name
Eur J Cancer Care (Engl)journal_title
European journal of cancer careauthors
Peros G,Sakorafas GH,Konstantoudakis G,Giannopoulos GA,Petropoulou K,Parasi Adoi
10.1111/j.1365-2354.2007.00894.xsubject
Has Abstractpub_date
2010-05-01 00:00:00pages
393-402issue
3eissn
0961-5423issn
1365-2354pii
ECC894journal_volume
19pub_type
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