Abstract:
:We assessed the quality of life (QoL) associated with patient's characteristics and different cancer treatments among Chinese breast cancer survivors in Taiwan. A cross-sectional survey was conducted in 2017 where 193 patients with hormone receptor-positive/human epidermal growth factor receptor-2-negative metastatic breast cancer were recruited. Three QoL questionnaires were administered: European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30), its breast cancer supplementary measure (QLQ-BR23) and EQ-5D-5L. Multiple linear regression was performed to assess the association between QoL and cancer treatments, with adjustment for patient's characteristics. The mean age of study participants was 55.52 years. Simple linear regression showed that cancer stage and receiving chemotherapy were significantly associated with QoL scores (p < 0.05). Significant adverse effects of chemotherapy on QoL were found among early-stage cancer women (i.e., I or II), including poor cognitive and sexual functioning, and a higher symptom burden (i.e., dyspnoea, constipation, systematic therapy side effects). Multiple linear regression also revealed that receiving chemotherapy was significantly associated with poor QoL (e.g., lower functional health and higher symptom burden measured by the QLQ-BR23), compared to none chemotherapy (p < 0.05). Receiving chemotherapy was associated with poor QoL, especially among early-stage breast cancer patients.
journal_name
Eur J Cancer Care (Engl)journal_title
European journal of cancer careauthors
Ou HT,Chung WP,Su PF,Lin TH,Lin JY,Wen YC,Fang WTdoi
10.1111/ecc.13069subject
Has Abstractpub_date
2019-07-01 00:00:00pages
e13069issue
4eissn
0961-5423issn
1365-2354journal_volume
28pub_type
杂志文章abstract::This study aims to describe the experiences of nurses caring for cancer patients in non-specialist wards. The study was conducted in a large (420 beds) and small (32 beds) hospital in an area health service with urban and rural populations in the west of Sydney. A qualitative descriptive approach was utilized to colle...
journal_title:European journal of cancer care
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1365-2354.2005.00566.x
更新日期:2005-07-01 00:00:00
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journal_title:European journal of cancer care
pub_type: 杂志文章
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journal_title:European journal of cancer care
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journal_title:European journal of cancer care
pub_type: 杂志文章
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更新日期:2018-01-01 00:00:00
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journal_title:European journal of cancer care
pub_type: 杂志文章
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journal_title:European journal of cancer care
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journal_title:European journal of cancer care
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pub_type: 杂志文章
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journal_title:European journal of cancer care
pub_type: 临床试验,杂志文章,随机对照试验,评审
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