Abstract:
OBJECTIVES:Alumina toughening enhances the mechanical properties of zirconia ceramics but the biocompatibility of this material has rarely been addressed. In this study, we examined the osteoblast response to alumina-toughened zirconia (ATZ) with different surface topographies. MATERIAL AND METHODS:Human osteoblasts isolated from maxillary biopsies of four patients were cultured and seeded onto disks of the following substrates: ATZ with a machined surface, airborne-particle abraded ATZ, airborne-particle abraded and acid etched ATZ. Airborne-particle abraded and acid etched titanium (SLA) and polystyrene disks served as a reference control. The surface topography of the various substrates was characterized by profilometry (R(a), R(p-v)) and scanning electron microscopy (SEM). Cell proliferation, cell-covered surface area, alkaline phophatase (ALP) and osteocalcin production were determined. The cell morphology was analyzed on SEM images. RESULTS:The surface roughness of ATZ was increased by airborne-particle abrasion, but with the R(a) and R(p-v) values showing significantly lower values compared with SLA titanium (Mann-Whitney U-test P<0.05). The proliferation assay revealed no statistically significant differences between the ATZ substrates, SLA titanium and polystyrene (Kruskal-Wallis test, P>0.05). All substrates were densely covered by osteoblasts. ALP and osteocalcin production was similar on the examined surfaces. Cell morphology analysis revealed flat-spread osteoblasts with cellular extensions on all substrates. CONCLUSIONS:These results indicate that ATZ may be a viable substrate for the growth and differentiation of human osteoblasts. Surface modification of ATZ by airborne-particle abrasion alone or in combination with acid etching seems not to interfere with the growth and differentiation of the osteoblasts.
journal_name
Clin Oral Implants Resjournal_title
Clinical oral implants researchauthors
Kohal RJ,Baechle M,Han JS,Hueren D,Huebner U,Butz Fdoi
10.1111/j.1600-0501.2009.01735.xsubject
Has Abstractpub_date
2009-11-01 00:00:00pages
1265-71issue
11eissn
0905-7161issn
1600-0501pii
CLR1735journal_volume
20pub_type
杂志文章abstract:OBJECTIVES:To systematically review changes in mucosal soft tissue thickness and keratinised mucosa width after soft tissue grafting around dental implants. MATERIALS AND METHODS:An electronic literature search was conducted of the MEDLINE database published between 2009 and 2014. Sequential screenings at the title, a...
journal_title:Clinical oral implants research
pub_type: 杂志文章,评审
doi:10.1111/clr.12606
更新日期:2017-01-01 00:00:00
abstract:AIM:This study sought to investigate dimensional changes to the alveolar bone following extraction and application of novel devices used for obturation of socket orifice (socket cap) and space maintenance in sockets with facial dehiscence (socket cage). MATERIAL AND METHODS:Six Macaca fascicularis had six teeth each r...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12521
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVES:The purpose of this in vitro study was to evaluate fracture loads of implant-supported zirconia-based prostheses fabricated with different veneer materials (resin-based material and lithium disilicate ceramics). MATERIAL AND METHODS:Forty-four zirconia-based molar prostheses were fabricated on dental implan...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.13135
更新日期:2018-04-01 00:00:00
abstract:OBJECTIVES:The aim of the study was to investigate whether bone marrow aspirates (BMA) and concentrates (BMAC) influence the grafts' stability when added to deproteinized bovine bone mineral (DBBM) within the first 6 months after maxillary sinus augmentation. MATERIAL AND METHODS:26 CT data of 13 patients undergoing b...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12101
更新日期:2014-02-01 00:00:00
abstract:OBJECTIVE:To evaluate the influence of the crown-to-implant ratio (C/I) ratio and different implant prosthetic treatment modalities on crestal bone loss around dental implants placed in the posterior region. MATERIAL AND METHODS:A total of 192 ITI dental implants were consecutively placed in premolars and molars of 83...
journal_title:Clinical oral implants research
pub_type: 临床试验,杂志文章
doi:10.1111/j.1600-0501.2006.01307.x
更新日期:2007-12-01 00:00:00
abstract::Sandblasted and acid-etched (SLA) implants were recently introduced to reduce the healing period between surgery and prosthesis. In this split-mouth study, SLA implants were compared to titanium plasma-sprayed (TPS) implants under loaded conditions one year after placement in 32 healthy patients, with comparable bilat...
journal_title:Clinical oral implants research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1034/j.1600-0501.2001.120604.x
更新日期:2001-12-01 00:00:00
abstract::The information concerning the molecular events taking place in onlay bone grafts are still incipient. The objective of the present study is to correlate the effects of perforation of resident bone bed on (1) the timing of onlay autogenous graft revascularization; (2) the maintenance of volume/density of the graft (as...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2007.01485.x
更新日期:2008-04-01 00:00:00
abstract::Parkinson's disease (PD) often affects the oro-pharyngeal musculature, leading to problems with speaking, chewing and swallowing. The inevitable reduction in food and fluid intake contributes to the further deterioration of neurological symptoms. Parkinson's disease patients have great difficulties in adjusting to the...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.2000.011006566.x
更新日期:2000-12-01 00:00:00
abstract:OBJECTIVES:To measure in vivo impact of dense bone overheating on implant osseointegration and peri-implant bone resorption comparing different bur irrigation methods vs. no irrigation. MATERIALS AND METHODS:Twenty TI-bone implants were inserted in the inferior edge of mandibles of sheep. Different cooling procedures ...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12127
更新日期:2014-06-01 00:00:00
abstract:OBJECTIVES:The aim of the present study was to assess the influence of either recombinant human growth and differentiation factor 5 (rhGDF-5)- or recombinant human bone morphogenetic protein 2 (rhBMP-2)-coated natural bone mineral (NBM) on guided bone regeneration in a rat calvarial defect model. MATERIAL AND METHODS:...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2009.01796.x
更新日期:2009-11-01 00:00:00
abstract::A clinical and radiographical study was performed to evaluate the treatment outcome of single tooth replacements with artificial crowns retained to implants installed according to a 1-stage surgical procedure and immediate loading (Experimental Group = EG) in comparison to the original 2-stage concept (Control Group =...
journal_title:Clinical oral implants research
pub_type: 临床试验,杂志文章
doi:10.1034/j.1600-0501.2000.011001026.x
更新日期:2000-02-01 00:00:00
abstract:OBJECTIVES:This study aimed to determine bone level changes after 5-6 years of follow-up for a large group of one-stage dental implants consecutively placed in private practice. Potential confounding factors influencing crestal bone loss (CBL) were also assessed. MATERIALS AND METHODS:A total of 378 transmucosal Strau...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12083
更新日期:2014-02-01 00:00:00
abstract:OBJECTIVES:The purpose of this study was to determine the relationship between patients with a history of periodontitis and development of cement-related peri-implant disease. MATERIALS AND METHODS:Seventy-seven patients with 129 implants for this retrospective analysis were selected from completed implant cases that ...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2012.02570.x
更新日期:2013-11-01 00:00:00
abstract:OBJECTIVES:The aim was to evaluate the peri-implant tissue levels over a 1-year period for implants connected to either convex or concave final abutments at the time of implant placement. MATERIALS AND METHODS:In this randomized, double masked, controlled clinical study, twenty-eight patients with one missing maxillar...
journal_title:Clinical oral implants research
pub_type: 杂志文章,随机对照试验
doi:10.1111/clr.13493
更新日期:2019-09-01 00:00:00
abstract::The aim of this study was to analyse the clinical outcome of two different surgical methods for the reconstruction of narrow edentulous ridges before implant installation: guided bone regeneration with e-PTFE membranes and autologous bone chips or grafting of autologous bone blocks without e-PTFE membranes. Thirty par...
journal_title:Clinical oral implants research
pub_type: 临床试验,杂志文章
doi:10.1034/j.1600-0501.1999.100404.x
更新日期:1999-08-01 00:00:00
abstract:OBJECTIVE:Using computed tomography, to compare vertical and volumetric bone augmentation after interposition grafting with bovine bone mineral matrix (GEISTLICH BIO-OSS® ) or hydroxyapatite/tricalcium phosphate (STRAUMANN® BONECERAMIC) for atrophic posterior mandible reconstruction through segmental osteotomy. MATERI...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12985
更新日期:2017-10-01 00:00:00
abstract::This paper presents the Orthosystem (Institute Straumann, Waldenburg/ Switzerland), a new endosseous orthodontic implant anchor system for palatal anchorage. The Orthosystem may replace compliance dependent extraoral anchoring aids for orthodontics and makes a bonding of well aligned mandibular dentition and it's use ...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.1996.070416.x
更新日期:1996-12-01 00:00:00
abstract:OBJECTIVES:The aim of the present systematic review was to analyze the survival and complication rates of zirconia-based and metal-ceramic implant-supported single crowns (SCs). MATERIALS AND METHODS:An electronic MEDLINE search complemented by manual searching was conducted to identify randomized controlled clinical ...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.13306
更新日期:2018-10-01 00:00:00
abstract:OBJECTIVES:This retrospective cross-sectional study aimed to evaluate the prevalence of biologic complications of implants in patients treated by fixed implant supported prosthesis without regular maintenance program. MATERIALS AND METHODS:One hundred thirty-four patients with 478 implants, installed during a 10-year ...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12800
更新日期:2017-03-01 00:00:00
abstract:PURPOSE:To compare: (i) the incidence of soft tissue dehiscences; (ii) bone resorption before and after implant placement; and (iii) the survival and success rates of implants placed in two groups of patients with severe bone defects of the jaws reconstructed with autogenous onlay bone grafts alone (control group) or i...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2012.02485.x
更新日期:2013-06-01 00:00:00
abstract:OBJECTIVE:The influence of progressively high concentrations of platelet-rich plasma (PRP) on human osteoblast hFOB1.19 proliferation was evaluated. MATERIAL AND METHODS:The PRP was obtained from a human source. Two experiments were conducted. In the first one, PRP was diluted to 50%, 25%, 12.5% and 6.125% (v/v) with ...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2005.01145.x
更新日期:2005-08-01 00:00:00
abstract::The prosthodontic section of the 1997 ITI Consensus Conference in Vitznau, Switzerland, examined a broad spectrum of issues related to the prosthodontic phase of dental implant therapy. Topics included diagnosis and treatment planning, considerations for the use of ITI prosthodontic components, management of the parti...
journal_title:Clinical oral implants research
pub_type: 共识发展会议,杂志文章,评审
doi:10.1034/j.1600-0501.2000.011s1101.x
更新日期:2000-01-01 00:00:00
abstract:OBJECTIVES:Serum C-reactive protein (CRP) has been shown to be a risk predictor for cardiovascular disease. Periodontal treatment reduces elevated CRP levels. The aim of this pilot investigation was to evaluate if dental implants placed after extractions in patients with end-stage periodontitis affect the serum CRP lev...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2004.01109.x
更新日期:2005-02-01 00:00:00
abstract:OBJECTIVE:This study histologically analyzed the healing of fresh frozen bone allograft (FFBA) with or without platelet-rich plasma (PRP) in bony defects surgically created in the mandible of dogs. MATERIAL AND METHODS:Bilateral resection defects were surgically created on the inferior border of the mandible in 10 dog...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12008
更新日期:2013-12-01 00:00:00
abstract:OBJECTIVES:The aim of this crossover study was to compare clinical denture base deformation with different attachments used for mandibular implant overdentures. MATERIALS AND METHODS:Twenty-four patients with edentulous mandibular ridges received two implants in the former canine regions. Three months thereafter, each...
journal_title:Clinical oral implants research
pub_type: 杂志文章,随机对照试验
doi:10.1111/clr.13552
更新日期:2020-02-01 00:00:00
abstract:PURPOSE:The objective of this biomechanical study was to explore the effect of bone micro-morphology on initial intraosseous stability of implants with different designs. MATERIAL AND METHODS:Straumann and Astra Tech dental implants were placed into anterior and posterior regions of completely edentulous maxilla and m...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2006.01265.x
更新日期:2006-08-01 00:00:00
abstract:BACKGROUND:There is limited knowledge regarding the strength of zirconia abutments with internal and external implant abutment connections and zirconia abutments supported by a titanium resin base (Variobase, Straumann) for narrow diameter implants. OBJECTIVES:To compare the fracture strength of narrow diameter abutme...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.13139
更新日期:2018-04-01 00:00:00
abstract:BACKGROUND:Non-surgical mechanical therapy of peri-implantitis (PI) with/without adjunctive measures yields limited clinical improvements. AIM:To evaluate the clinical outcomes following non-surgical mechanical therapy of PI with adjunctive application of a diode laser after an observation period ≥2 years. MATERIAL A...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12689
更新日期:2016-07-01 00:00:00
abstract:BACKGROUND:Cement-retained fixed implant-supported restorations involve the risk of excess cement, which can associate peri-implantitis. In connection with routine therapy using a methacrylate cement (Premier Implant Cement, Premier(®) Dental Products Company, Plymouth Meeting, PA, USA) to retain fixed implant-supporte...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12173
更新日期:2014-07-01 00:00:00
abstract:OBJECTIVE:A systematic review and meta-analysis are carried out to assess the scientific evidence that bisphosphonate therapy can decrease the success rate of dental implants. MATERIAL AND METHODS:The PubMed (Medline) database was used to search for articles published up until February 22, 2014. The meta-analysis was ...
journal_title:Clinical oral implants research
pub_type: 杂志文章,meta分析,评审
doi:10.1111/clr.12526
更新日期:2016-02-01 00:00:00