Moderate exposure to allogeneic blood products is not associated with reduced long-term survival after surgery for coronary artery disease.

abstract：BACKGROUND:Some studies suggest that the orbicularis oculi is resistant to neuromuscular blocking drugs and behaves like laryngeal muscles. Others report little or no difference between the orbicularis oculi and the adductor pollicis. These discrepancies could be related to the exact site of recording. The purpose of t...

journal_title：Anesthesiology

authors： Plaud B,Debaene B,Donati F

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:Offset analgesia, in which a disproportionally large amount of analgesia becomes apparent upon a slight decrease in noxious heat stimulation, has not been described previously in patients with chronic pain. METHODS:Offset analgesia responses in 10 patients with neuropathic pain (in both legs) were compared ...

journal_title：Anesthesiology

authors： Niesters M,Hoitsma E,Sarton E,Aarts L,Dahan A

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:In the event of trauma, emergency reversal of anticoagulation therapy may be required. However, no specific reversal agents are routinely available for the direct oral anticoagulants such as dabigatran. The authors investigated four-factor prothrombin complex concentrate (PCC) for treating dabigatran-induced...

journal_title：Anesthesiology

authors： Honickel M,Braunschweig T,van Ryn J,Ten Cate H,Spronk HM,Rossaint R,Grottke O

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Clonidine, an alpha 2-adrenoceptor agonist, has been shown to be effective as a preanesthetic medication in adults. The current study was designed to investigate the efficacy of two doses of oral clonidine as a premedicant preceding oral atropine in children. METHODS:In a prospective, randomized, double-bli...

journal_title：Anesthesiology

authors： Mikawa K,Maekawa N,Nishina K,Takao Y,Yaku H,Obara H

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND:Xenon is a general anesthetic with neuroprotective properties. Xenon inhibition at the glycine-binding site of the N-Methyl-D-aspartate (NMDA) receptor mediates xenon neuroprotection against ischemic injury in vitro. Here we identify specific amino acids important for xenon binding to the NMDA receptor, with...

journal_title：Anesthesiology

authors： Armstrong SP,Banks PJ,McKitrick TJ,Geldart CH,Edge CJ,Babla R,Simillis C,Franks NP,Dickinson R

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Perfluorocarbon liquids are being used experimentally and in clinical trials for the treatment of acute lung injury. Their resemblance to inhaled anesthetic agents suggests the possibility of application by vaporization. The authors' aim was to develop the technical means for perfluorocarbon vaporization and...

journal_title：Anesthesiology

authors： Bleyl JU,Ragaller M,Tschö U,Regner M,Kanzow M,Hübler M,Rasche S,Albrecht M

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND:Resiniferatoxin is a potent capsaicin analog. Intrathecal administration leads to selective, prolonged opening of the transient receptor potential V1 ion channel, which is localized mainly to C-fiber primary afferent nociceptive sensory neurons. Following work in laboratory animals, the authors explored the ...

journal_title：Anesthesiology

authors： Brown DC,Iadarola MJ,Perkowski SZ,Erin H,Shofer F,Laszlo KJ,Olah Z,Mannes AJ

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:In animals, systemic and intrathecal administration of the alpha2 -adrenergic receptor agonist dexmedetomidine results in robust antinociceptive effects in models of heat pain. In humans, systemically administered dexmedetomidine is approved for sedating patients in the intensive care unit. However, whether ...

journal_title：Anesthesiology

authors： Angst MS,Ramaswamy B,Davies MF,Maze M

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:We examined the effects of different anesthetics on cerebral oxygenation and systemic hemodynamics in patients undergoing surgery in beach chair position (BCP). Jugular venous bulb oxygen saturation (SjvO2) and regional cerebral tissue oxygen saturation (SctO2) were determined while patients were placed from...

journal_title：Anesthesiology

authors： Jeong H,Jeong S,Lim HJ,Lee J,Yoo KY

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Anesthetic drugs administered to immature animals may cause neurohistopathologic changes and alterations in behavior. The authors studied association between anesthetic exposure before age 4 yr and the development of reading, written language, and math learning disabilities (LD). METHODS:This was a populati...

journal_title：Anesthesiology

authors： Wilder RT,Flick RP,Sprung J,Katusic SK,Barbaresi WJ,Mickelson C,Gleich SJ,Schroeder DR,Weaver AL,Warner DO

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:With percutaneous recordings of muscle nerve sympathetic activity (MSA), it is possible to study interactions between the autonomic nervous system and anesthetics. This study describes the effects of propofol infusion both before and during microlaryngoscopy. METHODS:Nine patients participated. MSA was reco...

journal_title：Anesthesiology

authors： Sellgren J,Ejnell H,Elam M,Pontén J,Wallin BG

更新日期：1994-03-01 00:00:00

abstract：BACKGROUND:Vasospasm of arterial grafts represents an unpredictable complication of coronary artery surgery and may compromise myocardial revascularization, and treatment is based on empirical therapy with nitroglycerin. Because of the potential for tolerance to nitroglycerin to occur, the authors studied different vas...

journal_title：Anesthesiology

authors： Huraux C,Makita T,Montes F,Szlam F,Levy JH

更新日期：1998-06-01 00:00:00

abstract：:The ability of contrast echocardiography to assess regional myocardial perfusion during cardiopulmonary bypass in a dog model for coronary artery bypass surgery was evaluated. Sonicated Renograffin-76 microbubbles (meglumin diatrigoate and sodium diatrigoate) were injected into an aortic root proximal to an aortic occ...

journal_title：Anesthesiology

authors： Aronson S,Bender E,Feinstein SB,Heidenreich PH,Ellis J,Dick C,Roizen MF,Karp RB

更新日期：1990-02-01 00:00:00

abstract：BACKGROUND:Because ephedrine infusion (2 mg/min) does not adequately prevent spinal hypotension during cesarean delivery, the authors investigated whether adding phenylephrine would improve its efficacy. METHODS:Thirty-nine parturients with American Society of Anesthesiologists physical status I-II who were scheduled ...

journal_title：Anesthesiology

authors： Mercier FJ,Riley ET,Frederickson WL,Roger-Christoph S,Benhamou D,Cohen SE

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND:The minimum alveolar concentration (MAC) of volatile anesthetics is decreased during pregnancy, but MAC in the early postpartum period has not been reported. The aim of this study was to determine the MAC of isoflurane and to evaluate the relation between MAC and serum progesterone and beta-endorphin in pati...

journal_title：Anesthesiology

authors： Zhou HH,Norman P,DeLima LG,Mehta M,Bass D

更新日期：1995-06-01 00:00:00

abstract：INTRODUCTION:The knowledge on the mechanism of the postoperative exacerbation of sleep-disordered breathing may direct the perioperative management of patients with obstructive sleep apnea. The objective of this study is to investigate the factors associated with postoperative severity of sleep-disordered breathing. M...

journal_title：Anesthesiology

authors： Chung F,Liao P,Elsaid H,Shapiro CM,Kang W

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Endothelium-derived hyperpolarizing factor is thought to be a cytochrome P450-derived arachidonic acid metabolite that hyperpolarizes vascular smooth muscle cells by opening Ca(2+)-activated K+ channels (K+Ca channels). In the rabbit carotid artery both volatile and intravenous anesthetics inhibit the acetyl...

journal_title：Anesthesiology

authors： Kessler P,Lischke V,Hecker M

更新日期：1996-06-01 00:00:00

abstract：BACKGROUND:The design of an endotracheal tube has been shown to influence the passage of the tube through the glottis during fiberoptic intubation. Difficulty in passing the endotracheal tube can occur if the aryepiglottic folds obstruct the passage of the bevel. The relevant aspects of endotracheal tube design include...

journal_title：Anesthesiology

authors： Greer JR,Smith SP,Strang T

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND:Autoregressive modeling with exogenous input of middle latency auditory evoked potentials (A-Line autoregressive index [AAI]) has been proposed for monitoring depth of anesthesia in adults. The aim of this study was to evaluate the performance of the AAI during induction of anesthesia with sevoflurane and re...

journal_title：Anesthesiology

authors： Weber F,Bein T,Hobbhahn J,Taeger K

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:Ca is the dominant second messenger in primary sensory neurons. In addition, disrupted Ca signaling is a prominent feature in pain models involving peripheral nerve injury. Standard cytoplasmic Ca recording techniques use high K or field stimulation and dissociated neurons. To compare findings in intact dors...

journal_title：Anesthesiology

authors： Gemes G,Rigaud M,Koopmeiners AS,Poroli MJ,Zoga V,Hogan QH

更新日期：2010-07-01 00:00:00

abstract：:Postoperative itching is an important problem in the postoperative care unit. Pruritus after surgery may be drug induced (including intrathecal opioids) or secondary to a preexisting systemic disease. Mechanisms of itching are complex and not completely understood. The purpose of this review is to highlight new discov...

journal_title：Anesthesiology

authors： Waxler B,Dadabhoy ZP,Stojiljkovic L,Rabito SF

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:Recent advances have indicated a complex interplay between the autonomic nervous system and the innate immune system. Targeting neural networks for the treatment of sepsis is being developed as a therapeutic strategy. Because electroacupuncture at select acupoints can modulate activities of the autonomic ner...

journal_title：Anesthesiology

authors： Song JG,Li HH,Cao YF,Lv X,Zhang P,Li YS,Zheng YJ,Li Q,Yin PH,Song SL,Wang HY,Wang XR

更新日期：2012-02-01 00:00:00

abstract：:Thiopental-14C (30 mg and 10 muCi/kg) was injected intravenously into rats 36-48 hours following bilateral nephrectomy and one minute after pretreatment with sulfadimethoxine (30 mg/kg, iv). Control groups of normal and sham-operated animals were used. The distributions of radioactivity in plasma, brain, and heart 1, ...

journal_title：Anesthesiology

authors： Ghoneim MM,Pandya HB,Kelley SE,Fischer LJ,Corry RJ

更新日期：1976-12-01 00:00:00

abstract：BACKGROUND:Recent studies have revealed that N2O exerts its antinociceptive effect by inducing opioid peptide release in the brain stem, thereby activating the descending noradrenergic inhibitory neurons, which modulate pain processing in the spinal cord. However, the precise neuronal pathways that mediate these events...

journal_title：Anesthesiology

authors： Ohashi Y,Guo T,Orii R,Maze M,Fujinaga M

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND:Diphenhydramine is used as an antipruritic and antiemetic in patients receiving opioids. Whether it might exacerbate opioid-induced ventilatory depression has not been determined. METHODS:The ventilatory response to carbon dioxide during hyperoxia and the ventilatory response to hypoxia during hypercapnia (...

journal_title：Anesthesiology

authors： Babenco HD,Blouin RT,Conard PF,Gross JB

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND:Long-term neuroprotection by isoflurane has been questioned. The authors examined factors in experimental models potentially critical to definition of enduring isoflurane neuroprotection. METHODS:Rats were prepared for temporary middle cerebral artery occlusion (MCAO). Pericranial normothermia was maintaine...

journal_title：Anesthesiology

authors： Sakai H,Sheng H,Yates RB,Ishida K,Pearlstein RD,Warner DS

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Potentiation by general anesthetics of gamma-aminobutyric acid (GABA)-mediated inhibitory transmission in the central nervous system is attributed to GABA(A) receptor-mediated postsynaptic effects. However, the role of presynaptic mechanisms in general anesthetic action is not well characterized, and evidenc...

journal_title：Anesthesiology

authors： Murugaiah KD,Hemmings HC Jr

更新日期：1998-10-01 00:00:00

abstract：BACKGROUND:Vascular spasm is a well-known complication during vascular surgery. Topical lidocaine is frequently used to prevent this spasm. However, the effects of lidocaine on the endothelium-dependent antiaggregation are not clear. METHODS:The aggregation of platelet-rich plasma (PRP) obtained from healthy volunteer...

journal_title：Anesthesiology

authors： Az-ma T,Hardian,Yuge O

更新日期：1995-08-01 00:00:00

abstract：:Clinical studies have reported that body core temperature decreases during prolonged surgery and anesthesia. Although this finding has been attributed primarily to increased heat loss resulting from exposure of body cavities and infusion of cold solutions, it is generally recognized that anesthesia interferes with the...

journal_title：Anesthesiology

authors： Passias TC,Mekjavić IB,Eiken O

更新日期：1992-04-01 00:00:00

abstract：:Critically ill patients requiring mechanical ventilation are particularly susceptible to malnutrition. A knowledge of the energy requirements of these patients is essential in designing nutritional regimens. This study examines 45 resting energy-expenditure measurements performed in a group (n = 40) of postoperative, ...

journal_title：Anesthesiology

authors： Weissman C,Kemper M,Askanazi J,Hyman AI,Kinney JM

更新日期：1986-06-01 00:00:00