Brain stem opioidergic and GABAergic neurons mediate the antinociceptive effect of nitrous oxide in Fischer rats.

abstract：:Neurophysiologic and local cerebral metabolic mapping techniques indicate that seizures associated with lidocaine toxicity originate in subcortical brain structures. Normally local cerebral blood flow (l-CBF) is quantitatively coupled to local cerebral metabolic rate for glucose (l-CMRg). In the present study the resp...

journal_title：Anesthesiology

authors： Tommasino C,Maekawa T,Shapiro HM

更新日期：1986-06-01 00:00:00

abstract：BACKGROUND:Hydroxyethyl starch (HES) is commonly used as plasma expander during surgery but may be nephrotoxic as seen in studies in patients with sepsis. The authors hypothesized that the possible nephrotoxicity of 6% HES 130/0.4 could be revealed by measurements of urinary excretion of neutrophil gelatinase-associate...

journal_title：Anesthesiology

authors： Kancir AS,Pleckaitiene L,Hansen TB,Ekeløf NP,Pedersen EB

更新日期：2014-11-01 00:00:00

abstract：:Groups of rats were exposed to air or 80 per cent nitrous oxide for 30 min or 18 h, following which the brainstem opiate receptor density and the apparent affinity of these receptors to the radiolabeled agonist, 3H-dihydromorphine, were assayed, Thirty-minute exposure to nitrous oxide did not change opiate receptor ch...

journal_title：Anesthesiology

authors： Ngai SH,Finck AD

更新日期：1982-07-01 00:00:00

abstract：BACKGROUND:Initial postoperative core temperature is a physician and hospital performance measure. However, the extent to which core temperature changes during emergence from anesthesia and transport from the operating room to the postanesthesia care unit (PACU) remains unknown. Similarly, the accuracy of many noninvas...

journal_title：Anesthesiology

authors： Langham GE,Maheshwari A,Contrera K,You J,Mascha E,Sessler DI

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:The discrepancy between predicted effect-site concentration and measured bispectral index is problematic during intravenous anesthesia with target-controlled infusion of propofol and remifentanil. We hypothesized that bispectral index during total intravenous anesthesia would be more accurately predicted by ...

journal_title：Anesthesiology

authors： Lee HC,Ryu HG,Chung EJ,Jung CW

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:No externally validated risk score for postoperative pulmonary complications (PPCs) is currently available. The authors tested the generalizability of the Assess Respiratory Risk in Surgical Patients in Catalonia risk score for PPCs in a large European cohort (Prospective Evaluation of a RIsk Score for posto...

journal_title：Anesthesiology

authors： Mazo V,Sabaté S,Canet J,Gallart L,de Abreu MG,Belda J,Langeron O,Hoeft A,Pelosi P

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:While persistent opioid use after surgery has been the subject of a large number of studies, it is unknown how much variability in the definition of persistent use impacts the reported incidence across studies. The objective was to evaluate the incidence of persistent use estimated with different definitions...

journal_title：Anesthesiology

authors： Jivraj NK,Raghavji F,Bethell J,Wijeysundera DN,Ladha KS,Bateman BT,Neuman MD,Wunsch H

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:The value of exercise electrocardiography in the prediction of perioperative cardiac risk has yet to be defined. This study was performed to determine the predictive value of exercise electrocardiography as compared with clinical parameters and resting electrocardiography. METHODS:A total of 204 patients at...

journal_title：Anesthesiology

authors： Gauss A,Röhm HJ,Schäuffelen A,Vogel T,Mohl U,Straehle A,Meierhenrich R,Georgieff M,Steinbach G,Schütz W

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Previously, the authors found that anesthetized diabetic dogs had increased cerebral blood flow (CBF) and oxygen consumption (CMRO2). These results may have been influenced by anesthesia or surgery. The aim of this study was to determine whether CBF and CMRO2 are increased in the awake or anesthetized state ...

journal_title：Anesthesiology

authors： Sieber FE,Brown PR,Wu Y,Koehler RC,Traystman RJ

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND:Early acquisition of critical competencies by novice anesthesiology residents is essential for patient safety, but traditional training methods may be insufficient. The purpose of this study was to determine the effectiveness of high-fidelity simulation training of novice residents in the initial management ...

journal_title：Anesthesiology

authors： Park CS,Rochlen LR,Yaghmour E,Higgins N,Bauchat JR,Wojciechowski KG,Sullivan JT,McCarthy RJ

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:The observation that peripheral trauma causes enhanced spinal neuronal excitability has provided the scientific rationale for the concept of "pre-emptive analgesia." The premise has been that only noxious stimuli cause sensitization in sensory pathways, but this premise has not been tested in the conscious s...

journal_title：Anesthesiology

authors： Herrero JF,Headley PM

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Ketamine is a potent bronchodilator that, in clinically used concentrations, relaxes airway smooth muscle in part by a direct effect. This study explored the role of calcium concentration (Ca2+) in this relaxation. METHODS:Canine trachea smooth muscle strips were loaded with the fluorescent probe fura-2 and...

journal_title：Anesthesiology

authors： Pabelick CM,Jones KA,Street K,Lorenz RR,Warner DO

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND:Melanocortin peptides improve hemodynamic parameters and prevent death during severe hemorrhagic shock. In the present research we determined influences of a synthetic melanocortin 1/4 receptor agonist on the molecular changes that occur in rat liver during hemorrhage. METHODS:Controlled-volume hemorrhage w...

journal_title：Anesthesiology

authors： Lonati C,Sordi A,Giuliani D,Spaccapelo L,Leonardi P,Carlin A,Ottani A,Galantucci M,Grieco P,Catania A,Guarini S

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:The number of pregnancy-related deaths and severe maternal complications continues to rise in the United States, and the quality of obstetrical care across U.S. hospitals is uneven. Providing hospitals with performance feedback may help reduce the rates of severe complications in mothers and their newborns. ...

journal_title：Anesthesiology

authors： Glance LG,Hasley S,Glantz JC,Stevens TP,Faden E,Kreso MA,Pyne SG,Wissler RN,Fichter J,Gloff MS,Dick AW

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:Mutations in the ryanodine type 1 receptor (RyR1) are causative for malignant hyperthermia. Studies in human B lymphocytes have shown that measurement of RyR1-mediated intracellular Ca(2+) (Ca(2+)(i)) release can differentiate between normal and malignant hyperthermia-susceptible individuals. The authors hav...

journal_title：Anesthesiology

authors： McKinney LC,Butler T,Mullen SP,Klein MG

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:Volatile anesthetics relax airway smooth muscle (ASM) by altering intracellular Ca2+ concentration ([Ca2+]i). The authors hypothesized that relaxation is produced by decreasing sarcoplasmic reticulum Ca2+ content via increased Ca2+ "leak" through both inositol trisphosphate (IP3) and ryanodine receptor chann...

journal_title：Anesthesiology

authors： Pabelick CM,Prakash YS,Kannan MS,Warner DO,Sieck GC

更新日期：2001-07-01 00:00:00

abstract：:Pulmonary shunting (Qs/Qt) was measured in 16 anesthetized and paralyzed healthy beagle puppies during a control period when the end-expired CO2 concentration was 5 per cent and during alveolar hypoventilation, when the PaCO2 increased to 100 plus or minus 13 torr (mean plus or minus SE) and the ;Ha vecame 7.04 plus o...

journal_title：Anesthesiology

authors： Stone JG,Sullivan SF

更新日期：1975-04-01 00:00:00

abstract：BACKGROUND:High-frequency oscillatory ventilation (HFOV) at higher frequencies minimizes the tidal volume. However, whether increased frequencies during HFOV can reduce ventilator-induced lung injury remains unknown. METHODS:After the induction of acute respiratory distress syndrome in the model by repeated lavages, 2...

journal_title：Anesthesiology

authors： Liu S,Yi Y,Wang M,Chen Q,Huang Y,Liu L,Xie J,Zhou D,Qiu H

更新日期：2013-08-01 00:00:00

abstract：:Carotid endarterectomy requires temporary surgical occlusion of the involved carotid artery. During occlusion, the minimally acceptable (critical) internal carotid artery stump pressure is reported to be 50 torr, whereas for regional cerebral blood flow (rCBF), a critical range is reported to be 18-24 ml/100 g/min. Du...

journal_title：Anesthesiology

authors： McKay RD,Sundt TM,Michenfelder JD,Gronert GA,Messick JM,Sharbrough FW,Piepgras DG

更新日期：1976-10-01 00:00:00

abstract：BACKGROUND:Although evidence of its effects is tentative, acupuncture has long been used in the treatment of multiple maladies. So far, it has not been possible to discriminate the effects of the venue from specific results of needling itself, thus physicians merely depend on patients' statements. The authors investiga...

journal_title：Anesthesiology

authors： Agarwal-Kozlowski K,Lange AC,Beck H

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to determine whether either regional anesthesia (RA) or general anesthesia (GA) provided the best analgesia with the fewest adverse effects up to 2 weeks after ambulatory hand surgery. METHODS:Patients undergoing ambulatory hand surgery were randomly assigned to RA (axillary br...

journal_title：Anesthesiology

authors： McCartney CJ,Brull R,Chan VW,Katz J,Abbas S,Graham B,Nova H,Rawson R,Anastakis DJ,von Schroeder H

更新日期：2004-08-01 00:00:00

abstract：:To assess the effect of a glucose infusion on brain extracellular fluid (ECF) during systemic hypoxia, changes in glucose and lactate concentrations in cerebral ECF during and after moderate hypoxic hypoxia were measured in adult, conscious, unrestrained rats, with a microdialysis probe in the posterior hippocampus. T...

journal_title：Anesthesiology

authors： Harada M,Okuda C,Sawa T,Murakami T

更新日期：1992-10-01 00:00:00

abstract：BACKGROUND:The health-related effects of the operating room environment are unclear. The authors compared mortality risks of anesthesiologists to those of internal medicine physicians between 1979 and 1995. METHODS:The Physician Master File database, a listing of all US physicians, was used to identify anesthesiologis...

journal_title：Anesthesiology

authors： Alexander BH,Checkoway H,Nagahama SI,Domino KB

更新日期：2000-10-01 00:00:00

abstract：BACKGROUND:Lactate has been shown to be a prognostic biomarker in trauma. Although lactate clearance has already been proposed as an intermediate endpoint in randomized trials, its precise role in trauma patients remains to be determined. METHODS:Blood lactate levels and lactate clearance (LC) were calculated at admis...

journal_title：Anesthesiology

authors： Régnier MA,Raux M,Le Manach Y,Asencio Y,Gaillard J,Devilliers C,Langeron O,Riou B

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Intrathecal clonidine reduces tactile allodynia in animal models of neuropathic pain, and this effect is blocked by atropine. However, the role of tonic spinal cholinergic activity and its interaction with alpha2-adrenergic systems in normal and neuropathic conditions and to different sensory methods has not...

journal_title：Anesthesiology

authors： Paqueron X,Conklin D,Eisenach JC

更新日期：2003-07-01 00:00:00

abstract：:The thermoregulatory threshold for vasoconstriction has been studied in infants and children given isoflurane, but not in those given halothane anesthesia. More importantly, the effect of vasoconstriction on central temperature in pediatric patients remains unknown. Also unknown is the effect of caudal analgesia on va...

journal_title：Anesthesiology

authors： Bissonnette B,Sessler DI

更新日期：1992-03-01 00:00:00

abstract：:The purpose of this study was to evaluate the analgesic contribution of intravenously administered lidocaine and to correlate it with blood levels of the drug. In a double-blind manner, 14 healthy male volunteers received saline solution or lidocaine, 0.2 per cent, at three increasingly greater rates of infusion on tw...

journal_title：Anesthesiology

authors： Rowlingson JC,DiFazio CA,Foster J,Carron H

更新日期：1980-01-01 00:00:00

abstract：BACKGROUND:Compared to other perioperative complications, failure to rescue (i.e., death after suffering a complication) is highest after perioperative myocardial infarction (a myocardial infarction that occurs intraoperatively or within 30 days after surgery). The purpose of this study was to identify patient and surg...

journal_title：Anesthesiology

authors： Mazzarello S,McIsaac DI,Beattie WS,Fergusson DA,Lalu MM

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Both pain and the pharmacologic management of pain can cause the undesirable effect of sleep disruption. One goal of basic and clinical neuroscience is to facilitate rational drug development by identifying the brain regions and neurochemical modulators of sleep and pain. Adenosine is thought to be an endoge...

journal_title：Anesthesiology

authors： Tanase D,Baghdoyan HA,Lydic R

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:A combination of opioid and nonopioid analgesic drugs may improve the quality of postoperative analgesia as well as reduce opioid requirements and their associated side effects. Studies have shown synergism between gabapentin and morphine in animal and human experiments and in the treatment of incisional pai...

journal_title：Anesthesiology

authors： Turan A,Karamanlioğlu B,Memiş D,Hamamcioglu MK,Tükenmez B,Pamukçu Z,Kurt I

更新日期：2004-04-01 00:00:00