Abstract:
:The ability of contrast echocardiography to assess regional myocardial perfusion during cardiopulmonary bypass in a dog model for coronary artery bypass surgery was evaluated. Sonicated Renograffin-76 microbubbles (meglumin diatrigoate and sodium diatrigoate) were injected into an aortic root proximal to an aortic occlusion clamp root while dogs were on cardiopulmonary bypass, with the heart arrested in diastole. Echocardiographic contrast-enhanced regions of myocardial perfusion were easily visualized. Differences in contrast-enhanced myocardial regions depended on coronary artery occlusion or patency. The contrast-enhanced images of myocardial perfusion showed that, for a given myocardial segment of the supplying vessel, the presence or absence of contrast effect reliably predicted vessel occlusion or patency (P less than .01). In the future contrast echocardiography may allow the direct assessment of regional myocardial perfusion in the operating room.
journal_name
Anesthesiologyjournal_title
Anesthesiologyauthors
Aronson S,Bender E,Feinstein SB,Heidenreich PH,Ellis J,Dick C,Roizen MF,Karp RBsubject
Has Abstractpub_date
1990-02-01 00:00:00pages
295-301issue
2eissn
0003-3022issn
1528-1175journal_volume
72pub_type
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