Contrast echocardiography: a method to visualize changes in regional myocardial perfusion in the dog model for CABG surgery.

Abstract:

:The ability of contrast echocardiography to assess regional myocardial perfusion during cardiopulmonary bypass in a dog model for coronary artery bypass surgery was evaluated. Sonicated Renograffin-76 microbubbles (meglumin diatrigoate and sodium diatrigoate) were injected into an aortic root proximal to an aortic occlusion clamp root while dogs were on cardiopulmonary bypass, with the heart arrested in diastole. Echocardiographic contrast-enhanced regions of myocardial perfusion were easily visualized. Differences in contrast-enhanced myocardial regions depended on coronary artery occlusion or patency. The contrast-enhanced images of myocardial perfusion showed that, for a given myocardial segment of the supplying vessel, the presence or absence of contrast effect reliably predicted vessel occlusion or patency (P less than .01). In the future contrast echocardiography may allow the direct assessment of regional myocardial perfusion in the operating room.

journal_name

Anesthesiology

journal_title

Anesthesiology

authors

Aronson S,Bender E,Feinstein SB,Heidenreich PH,Ellis J,Dick C,Roizen MF,Karp RB

subject

Has Abstract

pub_date

1990-02-01 00:00:00

pages

295-301

issue

2

eissn

0003-3022

issn

1528-1175

journal_volume

72

pub_type

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