Effects of halothane and enflurane anesthesia on sympathetic beta-adrenoreceptor-mediated pulmonary vasodilation in chronically instrumented dogs.

abstract：BACKGROUND:The authors investigated the efficacy of bilateral suprazygomatic maxillary nerve block (SMB) for postoperative pain relief in infants undergoing cleft palate repair. METHODS:In this prospective, double-blind, single-site, randomized, and parallel-arm controlled trial, 60 children were assigned to undergo b...

journal_title：Anesthesiology

authors： Chiono J,Raux O,Bringuier S,Sola C,Bigorre M,Capdevila X,Dadure C

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:Pentobarbital decreases the gain of the baroreceptor reflex on the order of 50%, and this blunting is caused nearly entirely by decreasing cardioinhibitory parasympathetic activity. The most likely site of action of pentobarbital is the gamma-aminobutyric acid type A (GABA(A)) receptor. The authors tested wh...

journal_title：Anesthesiology

authors： Irnaten M,Walwyn WM,Wang J,Venkatesan P,Evans C,Chang KS,Andresen MC,Hales TG,Mendelowitz D

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND:Conflicting opinions are present in the literature regarding the origin of the negative inotropic effect of propofol on the myocardium. This study aims to resolve these discrepancies by investigating the inotropic effects of propofol the L-type calcium channels and the sodium-calcium exchanger (NCX). METHOD...

journal_title：Anesthesiology

authors： de Ruijter W,Stienen GJ,van Klarenbosch J,de Lange JJ

更新日期：2002-11-01 00:00:00

abstract：:The hepatic effects of repeated anesthesia of phenobarbital-induced Fischer 344 rats with 1% halothane/14% oxygen were investigated, after anesthetics were administered at either 1-day or 5-day intervals. Urinary excretion of fluoride, a product of reductive halothane metabolism, was increased in the 24-h period follo...

journal_title：Anesthesiology

authors： Plummer JL,Hall PD,Jenner MA,Cousins MJ

更新日期：1987-09-01 00:00:00

abstract：BACKGROUND:Elimination of daily-routine chest radiographs (CXRs) may influence chest computed tomography (CT) and ultrasound practice in critically ill patients. METHODS:This was a retrospective cohort study including all patients admitted to a university-affiliated intensive care unit during two consecutive periods o...

journal_title：Anesthesiology

authors： Kröner A,Binnekade JM,Graat ME,Vroom MB,Stoker J,Spronk PE,Schultz MJ

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Patients with brain injury are at high risk of extubation failure. METHODS:We conducted a prospective observational cohort study in four intensive care units of three university hospitals. The aim of the study was to create a score that could predict extubation success in patients with brain injury. RESULT...

journal_title：Anesthesiology

authors： Asehnoune K,Seguin P,Lasocki S,Roquilly A,Delater A,Gros A,Denou F,Mahé PJ,Nesseler N,Demeure-Dit-Latte D,Launey Y,Lakhal K,Rozec B,Mallédant Y,Sébille V,Jaber S,Le Thuaut A,Feuillet F,Cinotti R,ATLANREA group.

更新日期：2017-08-01 00:00:00

abstract：:The inhibitory effects of three inhalation anesthetics, i.e., halothane, enflurane, and isoflurane, on superoxide production and the intracellular mobilization of calcium in human neutrophils were studied. The superoxide production induced by N-formyl-methionyl-leucyl-phenylalanine (FMLP) was inhibited by the anesthet...

journal_title：Anesthesiology

authors： Nakagawara M,Takeshige K,Takamatsu J,Takahashi S,Yoshitake J,Minakami S

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND:There is substantial and growing literature on the actions of general anesthetics on a variety of neurotransmitter-gated ion channels, with the greatest attention being focused on inhibitory gamma-amino butyric acid type A receptors. In contrast, glutamate receptors, the most important class of fast excitato...

journal_title：Anesthesiology

authors： Plested AJ,Wildman SS,Lieb WR,Franks NP

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND:Because tactile evaluation is the most common form of clinical neuromuscular monitoring, this study examines the relative efficacy of antagonizing residual block at different levels of recovery of the tactile train-of-four (TOF) response. METHODS:Anesthesia was induced in 64 adults with 2-5 microg/kg fentan...

journal_title：Anesthesiology

authors： Kirkegaard H,Heier T,Caldwell JE

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Renal ischemia-reperfusion injury (IRI) is a major cause of acute kidney injury and often leads to multiorgan dysfunction and systemic inflammation. Volatile anesthetics have potent antiinflammatory effects. We aimed to determine whether the representative volatile anesthetic isoflurane protects against acut...

journal_title：Anesthesiology

authors： Kim M,Park SW,Kim M,D'Agati VD,Lee HT

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:Lidocaine inhalation attenuates histamine-induced bronchospasm while evoking airway anesthesia. Because this occurs at plasma concentrations much lower than those required for intravenous lidocaine to attenuate bronchial reactivity, this effect is likely related to topical airway anesthesia and presumably in...

journal_title：Anesthesiology

authors： Groeben H,Grosswendt T,Silvanus MT,Pavlakovic G,Peters J

更新日期：2001-03-01 00:00:00

abstract：BACKGROUND:Volatile anesthetics relax airway smooth muscle (ASM) by altering intracellular Ca2+ concentration ([Ca2+]i). The authors hypothesized that relaxation is produced by decreasing sarcoplasmic reticulum Ca2+ content via increased Ca2+ "leak" through both inositol trisphosphate (IP3) and ryanodine receptor chann...

journal_title：Anesthesiology

authors： Pabelick CM,Prakash YS,Kannan MS,Warner DO,Sieck GC

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:Kinins (e.g., bradykinin) acting through the constitutively expressed B2 and the injury-induced B1 receptors are involved in pain and hyperalgesia, as previously shown by use of receptor-selective antagonists and single-receptor knockout models. Because the overall contribution of kinins to painful processes...

journal_title：Anesthesiology

authors： Cayla C,Labuz D,Machelska H,Bader M,Schäfer M,Stein C

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:The Shannon entropy is a standard measure for the order state of sequences. It quantifies the degree of skew of the distribution of values. Increasing hypnotic drug concentrations increase electroencephalographic amplitude. The probability density function of the amplitude values broadens and flattens, there...

journal_title：Anesthesiology

authors： Bruhn J,Lehmann LE,Röpcke H,Bouillon TW,Hoeft A

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:Postoperative respiratory failure is associated with increased morbidity and mortality, as well as high costs of hospital care. METHODS:Using electronic anesthesia records, billing data, and chart review, the authors developed and validated a score predicting reintubation in the hospital after primary extub...

journal_title：Anesthesiology

authors： Brueckmann B,Villa-Uribe JL,Bateman BT,Grosse-Sundrup M,Hess DR,Schlett CL,Eikermann M

更新日期：2013-06-01 00:00:00

abstract：:The authors performed a randomized, prospective trial comparing enflurane, halothane, and isoflurane (each administered with nitrous oxide) to establish which inhaled anesthetic produced the fewest complications and the most rapid induction of anesthesia for children undergoing general anesthesia for diagnostic proced...

journal_title：Anesthesiology

authors： Fisher DM,Robinson S,Brett CM,Perin G,Gregory GA

更新日期：1985-12-01 00:00:00

abstract：:Intravenous lidocaine has been shown to relieve acute postoperative pain and chronic neuropathic pain. It is not known whether analgesia produced by 2-10 micrograms/ml plasma concentrations of lidocaine is due to an effect on peripheral-pain-transducing nerves or to central nervous system effects. The current study ex...

journal_title：Anesthesiology

authors： Tanelian DL,MacIver MB

更新日期：1991-05-01 00:00:00

abstract：:To study the cerebral protective effects of hypothermia in arterial hypoxia, anesthetized (70% N2O), mechanically ventilated rats were cooled to a body temperature of 27 C. Hypoxia was induced by decreasing the oxygen content in the inspired gas mixture either to 6-7 per cent or to 2.5-3 per cent. This reduced mean Pa...

journal_title：Anesthesiology

authors： Carlsson C,Hägerdal M,Siesjö BK

更新日期：1976-01-01 00:00:00

abstract：:The authors undertook a prospective study of 30 patients undergoing halothane anesthesia for coronary-artery revascularization to ascertain which clinically monitored hemodynamic variables--or combination of variables--associated with myocardial oxygen supply and demand best predict myocardial ischemia. Simultaneous r...

journal_title：Anesthesiology

authors： Lieberman RW,Orkin FK,Jobes DR,Schwartz AJ

更新日期：1983-07-01 00:00:00

abstract：BACKGROUND:Few data support an association between blood pressure variability and clinical outcomes during cardiac surgery. We tested the hypothesis that intraoperative systolic blood pressure variability outside a targeted blood pressure range predicts 30-day mortality in patients undergoing cardiac surgery. METHODS:...

journal_title：Anesthesiology

authors： Aronson S,Stafford-Smith M,Phillips-Bute B,Shaw A,Gaca J,Newman M,Cardiothoracic Anesthesiology Research Endeavors.

更新日期：2010-08-01 00:00:00

abstract：:The slow positive (P2) wave of the evoked electrospinogram was recorded from the dorsal epidural space in man. The waveform characteristics of the P2 wave were similar to those of the dorsal cord positive wave (P wave), which is believed to be caused by the primary afferent depolarization (PAD) and to be related to pr...

journal_title：Anesthesiology

authors： Shimoji K,Ito Y,Oama K,Sawa T,Ikezono E

更新日期：1975-10-01 00:00:00

abstract：BACKGROUND:Telephone quitlines that provide counseling support are efficacious in helping cigarette smokers quit and have been widely disseminated; currently, they are underused. Surgery represents a teachable moment for smoking cessation, which can benefit surgical outcomes; however, few surgical patients receive smok...

journal_title：Anesthesiology

authors： Warner DO,Klesges RC,Dale LC,Offord KP,Schroeder DR,Shi Y,Vickers KS,Danielson DR

更新日期：2011-04-01 00:00:00

abstract：:Postoperative adrenocortical function was compared in 23 out-patients receiving either thiopental, 4 mg/kg, for induction and a thiopental infusion, 0.26 mg . kg-1 . min-1, in combination with nitrous oxide 70% for maintenance of anesthesia (control); etomidate, 0.4 mg/kg, for induction followed by an etomidate infusi...

journal_title：Anesthesiology

authors： Wagner RL,White PF

更新日期：1984-12-01 00:00:00

abstract：BACKGROUND:Some studies suggest that the orbicularis oculi is resistant to neuromuscular blocking drugs and behaves like laryngeal muscles. Others report little or no difference between the orbicularis oculi and the adductor pollicis. These discrepancies could be related to the exact site of recording. The purpose of t...

journal_title：Anesthesiology

authors： Plaud B,Debaene B,Donati F

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:The number of pregnancy-related deaths and severe maternal complications continues to rise in the United States, and the quality of obstetrical care across U.S. hospitals is uneven. Providing hospitals with performance feedback may help reduce the rates of severe complications in mothers and their newborns. ...

journal_title：Anesthesiology

authors： Glance LG,Hasley S,Glantz JC,Stevens TP,Faden E,Kreso MA,Pyne SG,Wissler RN,Fichter J,Gloff MS,Dick AW

更新日期：2019-08-01 00:00:00

abstract：:A carcinogen bioassay of enflurane was performed in Swiss/ICR mice. Two groups of weanling mice, each of 125 males and 125 females, were exposed to eigher a maximum tolerated dose of enflurane, 3000 ppm (0.3 per cent v/v) or compressed air for 4 hs per day, 5 days per week. After 52 weeks exposure, 25 males and 25 fem...

journal_title：Anesthesiology

authors： Baden JM,Egbert B,Mazze RI

更新日期：1982-01-01 00:00:00

abstract：:Various animal models have been used for studies of bupivacaine cardiovascular toxicity. These studies are difficult to relate to the clinical situation, since the disposition of bupivacaine in the various species is unknown. The serum protein binding of bupivacaine, therefore, was determined in human, sheep, monkey, ...

journal_title：Anesthesiology

authors： Coyle DE,Denson DD,Thompson GA,Myers JA,Arthur GR,Bridenbaugh PO

更新日期：1984-08-01 00:00:00

abstract：BACKGROUND:The mechanisms underlying depression-associated pain remain poorly understood. Using a mouse model of depression, the authors hypothesized that the central amygdala-periaqueductal gray circuitry is involved in pathologic nociception associated with depressive states. METHODS:The authors used chronic restrai...

journal_title：Anesthesiology

authors： Yin W,Mei L,Sun T,Wang Y,Li J,Chen C,Farzinpour Z,Mao Y,Tao W,Li J,Xie W,Zhang Z

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Airway pressure-release ventilation provides ventilation comparable to controlled mechanical ventilation (CMV), but with lower peak airway pressures and less dead-space ventilation. To obtain these advantages for patients administered general anesthesia, the authors (1) designed a mode similar to airway pres...

journal_title：Anesthesiology

authors： Bratzke E,Downs JB,Smith RA

更新日期：1998-08-01 00:00:00

abstract：BACKGROUND:Ethical conduct in human research in anesthesia includes approval by an institutional review board (IRB) or ethics committee and informed consent. Evidence of these is sometimes lacking in journal publications. METHODS:The authors reviewed all publications involving human subjects in six leading anesthesia ...

journal_title：Anesthesiology

authors： Myles PS,Tan N

更新日期：2003-11-01 00:00:00