Abstract:
PURPOSE:The purpose of this study was to assess the association between antidepressant use and incident coronary heart disease (CHD) events in a sample of individuals without known baseline heart disease. PARTICIPANTS AND METHODS:We studied a group of 970 randomly selected community-dwelling adults in the 1995 Nova Scotia Health Survey, who were followed for up to 10 years. Antidepressant usage was classified according to class. Primary outcomes were acute coronary syndrome hospitalizations or cardiac death, determined by centralized, standardized ratings. RESULTS:During a follow-up period of 10 years, there were 147 incident CHD events (139 acute coronary syndromes and 8 cardiac deaths) during the 8129 person-years of observation (incidence rate = 18.1 events/1000 person-years). In a model controlling for age, sex, Framingham risk score, time to last annual exam, aspirin exposure, and depressive symptoms, an increased risk of CHD events was associated with tricyclic antidepressant exposure (adjusted hazard ratio, 2.10; 95% confidence interval, 1.09-4.06; p = 0.027). CONCLUSION:In this prospective population-based study, exposure to tricyclic antidepressants was associated with higher risk of first CHD events.
journal_name
Int J Cardioljournal_title
International journal of cardiologyauthors
Rosenberg LB,Whang W,Shimbo D,Shah A,Shapiro PA,Davidson KWdoi
10.1016/j.ijcard.2009.06.036subject
Has Abstractpub_date
2010-11-05 00:00:00pages
124-5issue
1eissn
0167-5273issn
1874-1754pii
S0167-5273(09)00712-8journal_volume
145pub_type
信件,随机对照试验abstract::We investigated the influence of Holter duration on the detection of recurrences after ablation for atrial fibrillation (AF). Two-hundred-and-fifteen patients underwent a 7-day Holter ECG at 6 months after catheter ablation. We analyzed the number of patients who had a recurrence within the first 24, 48, 72 h etc. up ...
journal_title:International journal of cardiology
pub_type: 信件
doi:10.1016/j.ijcard.2008.10.004
更新日期:2010-03-18 00:00:00
abstract::Maintenance of normal potassium (K(+)) homeostasis has become an increasingly important limiting factor in the therapy of heart failure (HF). With the application of loop diuretics and digoxin, hypokalemia has become a frequent and feared side effect of treatment. Low serum K(+) in HF may be also a marker of increased...
journal_title:International journal of cardiology
pub_type: 杂志文章,评审
doi:10.1016/j.ijcard.2011.06.121
更新日期:2012-06-28 00:00:00
abstract::The aim of this study, using right ventricular endomyocardial biopsies, was to determine whether adenylyl cyclase activity is decreased-despite cardiac denervation-in human failing transplanted myocardium. beta-Adrenoceptor-stimulated adenylyl cyclase activity in membranes of moderately failing transplanted hearts was...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/0167-5273(96)02709-x
更新日期:1996-09-01 00:00:00
abstract::We examined 16 patients, aged 24 to 73, with ICD. Condition of qualification to the examined group was experiencing many discharges (from 25 to above 200) or electric shock (3 or more discharges following one after another). Most of the patients (14) were afraid of ICD discharges. 11 patients presented psychopathologi...
journal_title:International journal of cardiology
pub_type: 信件
doi:10.1016/j.ijcard.2007.08.027
更新日期:2009-02-20 00:00:00
abstract:BACKGROUND:Left ventricular (LV) global longitudinal strain (GLS) can detect an early dysfunction in arterial hypertension. We investigated regional LV patterns of longitudinal strain (LS) and base-to-apex behaviour in newly diagnosed, never-treated hypertensive patients (HTN) without LV hypertrophy. METHODS:180 HTN a...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2020.01.038
更新日期:2020-04-01 00:00:00
abstract:BACKGROUND:Cheyne-Stokes respiration with central sleep apnea (CSR-CSA) is common in patients with severe cardiac failure. Various modes of positive airway pressure have been suggested as treatments. The authors hypothesized that high frequency jet ventilation (HFJV) can improve central sleep apnea in patients with chr...
journal_title:International journal of cardiology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ijcard.2005.02.005
更新日期:2006-01-13 00:00:00
abstract::We have studied, by light and electron microscopy, left ventricular endomyocardial biopsy specimens from 18 African patients (14 men) with idiopathic dilated cardiomyopathy in Nairobi. Nine patients (50%) had evidence of healing myocarditis, that is the presence of a mild inflammatory cell infiltration within the myoc...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/0167-5273(93)90156-b
更新日期:1993-09-01 00:00:00
abstract:BACKGROUND:Degenerative disease of the mitral valve (DDMV) is always accompanied by lengthening and/or rupture of chordae tendineae. However, the mechanisms and the mode of chordal rupture remain controversial, and the pathologic anatomy of the apparently healthy chordae has mostly been overlooked. We analyze the struc...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2012.04.092
更新日期:2013-08-20 00:00:00
abstract::We sought to investigate the relative clinical significance of target and nontarget lesions repeated percutaneous coronary intervention (re-PCI) in patients implanted with drug-eluting stents (DES). Out of 2626 consecutive DES patients, we retrospectively selected 166 (6.3%; 123 males, aged 65±10 years) who had a clin...
journal_title:International journal of cardiology
pub_type: 信件
doi:10.1016/j.ijcard.2009.11.049
更新日期:2010-11-19 00:00:00
abstract:BACKGROUND:T2 weighted cardiovascular magnetic resonance (CMR) can detect intramyocardial hemorrhage (IMH) after ST-elevation myocardial infarction (STEMI). The long-term prognostic value of IMH beyond a comprehensive CMR assessment with late enhancement (LE) imaging including microvascular obstruction (MVO) is unclear...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2012.05.055
更新日期:2013-09-01 00:00:00
abstract::Cardiac sequelae of stab chest wounds may be various and dramatic, and the right ventricle is the most commonly injured chamber. Correct diagnosis of cardiac damage may be done up to many years after the trauma. We describe a rare case of isolated, unexpected flail tricuspid valve detected by transthoracic echocardiog...
journal_title:International journal of cardiology
pub_type: 信件
doi:10.1016/s0167-5273(98)00142-9
更新日期:1998-09-01 00:00:00
abstract:BACKGROUND:New-generation drug-eluting stents have demonstrated the mid-term efficacy and safety, but possible differences between stents may emerge in a long-term period. We compared long-term outcomes of patients with chronic stable angina and an isolated de-novo lesion in the proximal left anterior descending artery...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2015.01.044
更新日期:2015-03-15 00:00:00
abstract:BACKGROUND:Atorvastatin and remote ischemic preconditioning (RIPC) have beneficial cardiovascular protective effects. The aim of the study was to investigate possible effect of this drug alone and in combination with RIPC on the biochemical changes induced by ischemic/reperfusion injury (I/R) in a combined study with a...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2016.07.178
更新日期:2016-11-01 00:00:00
abstract:BACKGROUND:There is a controversy surrounding the correlation between fibrinogen (Fib) level and prognosis of coronary artery disease (CAD). We try to investigate the role of the subtypes of CAD in this controversy. METHODS:A retrospective analysis was conducted from a single center CAD registered database. 3020 conse...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2016.07.160
更新日期:2016-11-01 00:00:00
abstract:BACKGROUND:The incidence of congenital coronary anomalies is mainly derived from autopsy series and pre-participation exams in athletes. Limited data exist regarding the spectrum of coronary anomalies that can be detected in asymptomatic patients. We sought to describe echocardiographically detected congenital coronary...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2007.04.063
更新日期:2008-06-06 00:00:00
abstract::We evaluated the effects of bepridil hydrochloride, a long-acting calcium antagonist, on the electrocardiogram of 13 men with exertional angina. The drug decreased sinus rate (P = 0.01), increased the QT (P less than 0.001) and QTc interval (P less than 0.001), and produced T-wave changes in each patient. ...
journal_title:International journal of cardiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0167-5273(84)90191-8
更新日期:1984-09-01 00:00:00
abstract:BACKGROUND:Inflammation is a major contributor to atherosclerotic vascular disease. Inflammatory parameters such as C-reactive protein (CRP) and Interleukin-6 (IL-6) have been shown to be strong predictors of cardiovascular events. The association between preoperative inflammatory parameters and early graft occlusion a...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2006.09.004
更新日期:2007-08-09 00:00:00
abstract:BACKGROUND:Anticoagulation remains a controversial issue among hyperthyroid patients with atrial fibrillation (AF). We aimed to evaluate the prevalence of the thrombogenic milieu (TM), detected using transesophageal echocardiography (TEE), among patients with AF related to hyperthyroidism, and to correlate these findin...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2016.11.053
更新日期:2017-02-01 00:00:00
abstract:OBJECTIVE:The risk of ischemic stroke, systemic thromboembolism, and all-cause death among heart failure patients previously diagnosed with diabetes mellitus is poorly described. We evaluated the risk of these endpoints among heart failure patients without diagnosed atrial fibrillation according to the presence of diab...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2016.02.004
更新日期:2016-04-15 00:00:00
abstract:OBJECTIVES:To review our experience of surgical repair of post-infarction ventricular septal defect (VSD). METHODS:In the period 1983-2002, 50 patients underwent repair of VSD. Mean age was 66 years, male sex 52%. Infarct location was anterior in 60% and posterior in 40% of cases. Median interval between rupture and s...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2005.05.007
更新日期:2006-04-04 00:00:00
abstract::We studied the protective effect of metoprolol on emetine induced T wave changes in rabbits. None of the rabbits who were beta-blocked before administration of emetine develop the T wave changes observed consistently in the control group. These observations support our clinical impression that emetine-induced T wave c...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/0167-5273(84)90250-x
更新日期:1984-07-01 00:00:00
abstract:BACKGROUND:The association between lipid levels and stroke rates is less than lipid levels and coronary heart disease (CHD). OBJECTIVE:To assess if there are geographic, racial, and ethnic differences in total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C) a...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2016.06.091
更新日期:2016-10-01 00:00:00
abstract:BACKGROUND:The association of soluble interleukin-1 receptor-like 1 (ST2) with left ventricular (LV) remodeling is unclear in patients with a first ST-segment elevation myocardial infarction (STEMI). The objective of this work was to assess the relationship between ST2, a marker of inflammation, and cardiac magnetic re...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2018.06.073
更新日期:2018-11-01 00:00:00
abstract::Spontaneous coronary artery dissection (SCAD) causing acute myocardial infarction is a rare event. It occurs mostly in young women without traditional risk factors for coronary artery disease, particularly during the peripartum period. We describe two occurrences of SCAD in young women in whom coronary atherosclerosis...
journal_title:International journal of cardiology
pub_type: 信件
doi:10.1016/j.ijcard.2005.12.021
更新日期:2007-01-31 00:00:00
abstract::Ischemic heart disease is the major cause of death, disability and lost productivity in the developed countries of the world. The evolution of cardiac care units has improved patient survival from myocardial infarctions, but requires a high-tech, very expensive treatment facility. Chest pain centers, located in emerge...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/s0167-5273(99)00160-6
更新日期:2000-01-15 00:00:00
abstract::There is controversy about the influence of QT dispersion on the incidence of early ventricular arrhythmias in patients with acute myocardial infarction (AMI). The QT and QTc dispersion (QTd, QTcd) between two groups of patients with AMI were compared: 39 patients with early sustained ventricular tachycardia or ventri...
journal_title:International journal of cardiology
pub_type: 临床试验,杂志文章
doi:10.1016/s0167-5273(97)00226-x
更新日期:1997-12-19 00:00:00
abstract::In-stent Restenosis (ISR) is the Achilles heel for using of stent. Vascular brachytherapy (VBT) has been the principal scientifically investigated local therapy for coronary artery ISR. In our suggested method, a new type of stent, which is coated with Boron ((10)B) compound, is used. The coating layer of the stent co...
journal_title:International journal of cardiology
pub_type: 信件
doi:10.1016/j.ijcard.2008.04.036
更新日期:2009-08-14 00:00:00
abstract:AIM AND METHODS:Gender-related differences in clinical phenotype, in-hospital management and prognosis of acute heart failure (AHF) patients have been previously reported in European and US registries. The ALARM-HF survey is the first to include a cohort of 4953 patients hospitalized for AHF in 666 hospitals in 6 Europ...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2012.09.096
更新日期:2013-09-20 00:00:00
abstract::A 56-year-old man without previous medical history or risk factors for coronary artery disease, presented with chest pain 2 weeks after violent blunt chest trauma. He was as a spectator, beaten and kicked almost to death during an amateur soccer match. Because of embarrassment, this was denied till shortly after his d...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/s0167-5273(97)00320-3
更新日期:1998-02-28 00:00:00
abstract::A macroscopic pathological assessment of the coronary arteries of a pig's heart, in which stent implantation and intra-vascular ultrasound and thermography pullbacks were performed, shows that during percutaneous coronary catheterization and intervention, one of the major vessel traumas occurs in the very proximal par...
journal_title:International journal of cardiology
pub_type: 信件
doi:10.1016/j.ijcard.2006.05.046
更新日期:2006-11-18 00:00:00