Abstract：
:The aim of this study, using right ventricular endomyocardial biopsies, was to determine whether adenylyl cyclase activity is decreased-despite cardiac denervation-in human failing transplanted myocardium. beta-Adrenoceptor-stimulated adenylyl cyclase activity in membranes of moderately failing transplanted hearts was significantly decreased by 49% in comparison to non-failing transplanted hearts. Receptor-independent adenylyl cyclase stimulation (forskolin + GTP, forskolin + Mn2+) and the level of inhibitory G protein alpha-subunits were not significantly different in membranes of failing vs. non-failing transplanted myocardium. The results indicate that similar to failing non-transplanted myocardium the responsiveness to beta-adrenoceptor agonists is also decreased in failing transplanted myocardium.
journal_name
Int J Cardioljournal_title
International journal of cardiologyauthors
Reithmann C,von Scheidt W,Werdan Kdoi
10.1016/0167-5273(96)02709-xsubject
Has Abstractpub_date
1996-09-01 00:00:00pages
11-5issue
1eissn
0167-5273issn
1874-1754pii
S016752739602709Xjournal_volume
56pub_type
杂志文章abstract：OBJECTIVE:Vitamin K antagonists (VKA) are associated with increased vascular calcification which may lead to an elevated cardiovascular risk. If the direct anticoagulants (DOACs) have similar negative vascular effects is unknown. We evaluated the influence of different anticoagulation strategies on coronary artery dise...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2018.03.019
更新日期：2018-06-01 00:00:00
abstract：BACKGROUND:beta-blocker therapy for dilated or ischemic cardiomyopathy is now an accepted and effective treatment. However, little is known about its efficacy in patients with postoperative impaired left ventricular function. This retrospective study was designed to assess the effects of beta-blocker therapy in patient...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/s0167-5273(99)00215-6
更新日期：2000-03-31 00:00:00
abstract：:Mutations in genes encoding cytoskeletal proteins participate in the pathogenesis of familial dilated cardiomyopathy (fDCM). Additional factors including inflammatory reactions are believed to play a role in deterioration of left-ventricular function. An association of inflammatory fDCM with the HSPA1B 1267 A-->G poly...
journal_title：International journal of cardiology
pub_type： 信件
doi：10.1016/j.ijcard.2007.08.121
更新日期：2009-03-20 00:00:00
abstract：:We present an interesting case of paroxysmal hypertension in a young male caused by malignant pheochromocytoma. This patient, who had history of paroxysms of abdominal pain with severe hypertension, developed osseous metastasis in the first lumbar vertebra resulting in collapse of the vertebra and it caused paraplegia...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/0167-5273(92)90035-2
更新日期：1992-03-01 00:00:00
abstract：BACKGROUND:The safety and efficacy of the Promus Element stent have been recently demonstrated in a selected population from one randomized trial. The aim of this study was to describe the initial clinical experience with the everolimus eluting platinum chromium stent (Promus Element) in unselected patients from a real...
journal_title：International journal of cardiology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.ijcard.2011.12.057
更新日期：2013-07-15 00:00:00
abstract：:We describe 7 transplanted heart recipients from a single family with limb-girdle muscular dystrophy type 1B linked to a mutation of the LMNA gene in the splice donor site of the exon 9 (IVS 9+1:g>a). These patients did not display higher early postoperative or late complications than other heart transplant recipients...
journal_title：International journal of cardiology
pub_type： 信件
doi：10.1016/j.ijcard.2009.04.036
更新日期：2009-11-12 00:00:00
abstract：:Anti-cardiac receptor autoantibodies have been studied intensively last 10 years. A growing evidence, both in vitro and in vivo and both clinical and experimental studies, have supported that these anti-cardiac receptor autoantibodies, mainly anti-beta1 adrenoceptor autoantibodies, play a very important pathophysiolog...
journal_title：International journal of cardiology
pub_type： 杂志文章,评审
doi：10.1016/j.ijcard.2006.05.013
更新日期：2006-09-10 00:00:00
abstract：BACKGROUND:Atrial electrophysiological abnormalities have previously been reported in Brugada syndrome. We investigated the incidence and electrocardiographic predictors of atrial fibrillation (AF) in a Chinese cohort of Brugada syndrome patients. METHODS:A retrospective study of Brugada syndrome patients admitted to ...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2020.05.007
更新日期：2020-09-01 00:00:00
abstract：BACKGROUND:It is well known that estrogen can modulate distribution and function of adrenergic receptors in the heart of different species. We reported here gender differences in adrenergic responsiveness of electrically driven guinea pig left atria. METHODS:Experiments were performed on the guinea pigs divided in fou...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2007.05.040
更新日期：2008-09-16 00:00:00
abstract：BACKGROUND/OBJECTIVES:Optical coherence tomography (OCT) is widely used for evaluation of healing response to stent implantation. We sought to test the agreement between the 1-mm and 0.6-mm sampling intervals for assessment of the percentage of uncovered and malapposed struts by OCT. METHODS:Thirty-eight patients pres...
journal_title：International journal of cardiology
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.ijcard.2016.11.173
更新日期：2017-01-15 00:00:00
abstract：OBJECTIVES:Assessment of the long term outcome of mechanical valve prosthesis at pulmonary position in a population of grown-up congenital heart disease patients from a tertiary referral center. METHODS:From 1977 to 2007, 22 consecutive patients underwent a total of 25 pulmonary valve replacements with mechanical pros...
journal_title：International journal of cardiology
pub_type： 杂志文章,评审
doi：10.1016/j.ijcard.2010.04.004
更新日期：2011-07-15 00:00:00
abstract：BACKGROUND:Women have a higher morbidity and mortality than men after an acute coronary event. We analyzed the prescription rates of evidence-based pharmacological therapies for patients with stable coronary heart disease and whether there were any differences with respect to gender. DESIGN:This cross-sectional study ...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2007.12.115
更新日期：2009-04-17 00:00:00
abstract：BACKGROUND AND AIM:The problem of a possible gender bias in coronary heart disease management is still controversial. We studied gender differences in secondary preventive drug prescriptions and in referral to cardiac rehabilitation after acute coronary events in France. METHODS:An observational survey was carried out...
journal_title：International journal of cardiology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.ijcard.2003.04.003
更新日期：2004-02-01 00:00:00
abstract：BACKGROUND:The mitochondrial permeability transition pore (mPTP) plays an important role in ischemia-reperfusion in normotensive animals. Our study aims to define their participation in the ischemic preconditioning (IP) in hypertrophied hearts and to assess the role played by NO and mitochondrial ATP-dependent K channe...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2011.10.103
更新日期：2013-06-05 00:00:00
abstract：:Acute dissection of the ascending aorta may present with chest pain and haemopericardium. The following case illustrates an unusual differential diagnosis: rupture of a very large coronary artery aneurysm, diagnosed by transoesophageal echocardiography. ...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/s0167-5273(98)00086-2
更新日期：1998-06-01 00:00:00
abstract：:The effect and choice of a drug to control heart rate for symptomatic improvement in patients with isolated mitral stenosis with normal sinus rhythm (n = 10) or atrial fibrillation (n = 10) were studied. Digoxin (0.25-0.5 mg daily), metoprolol (50-100 mg twice a day) and verapamil (40-80 mg three times a day) were eva...
journal_title：International journal of cardiology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/0167-5273(89)90223-4
更新日期：1989-12-01 00:00:00
abstract：BACKGROUND:Recent population-based estimates for long-term cardiovascular disease (CVD) mortality after hospitalization for a first acute myocardial infarction (AMI) are not well established. METHODS:Data from the Swedish hospital discharge and death registries were used to record all first-ever hospital admissions in...
journal_title：International journal of cardiology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.ijcard.2010.10.047
更新日期：2012-03-22 00:00:00
abstract：:Low energy level irradiation (LLLI) has been found to modulate biological processes. The effect of LLLI on the development of acute myocardial infarction (MI) was investigated following chronic ligation of the left anterior descending (LAD) coronary artery in laboratory rats. The hearts of 22 rats were laser irradiate...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/s0167-5273(01)00503-4
更新日期：2001-09-01 00:00:00
abstract：AIM:To assess the prevalence of suboptimal bioresorbable vascular scaffold (BVS, Abbott Vascular, Santa Clara, California) deployment in real world practice with intracoronary optical coherence tomography (OCT) imaging. METHODS:Consecutive patients who underwent percutaneous coronary intervention using BVS and the fin...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2016.06.096
更新日期：2016-10-01 00:00:00
abstract：:Rhythm control of atrial fibrillation (AF) remains challenging, with modest long-term success rates. Atrial fibrosis has been associated with AF, but the clinical utility of assessment of this fibrosis has yet to be fully elucidated. In this paper we review the current state of understanding of the pathophysiology of ...
journal_title：International journal of cardiology
pub_type： 杂志文章,评审
doi：10.1016/j.ijcard.2016.06.144
更新日期：2016-10-01 00:00:00
abstract：:Seventy patients with acute myocardial infarction were studied by serial vectorcardiography. Eleven out of 70 patients had acute myocardial infarction, which consistently met the vectorcardiographic QRS-loop criteria of anteroseptal myocardial infarction within the 21 days follow-up period. From the first vectorcardio...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/0167-5273(94)90005-1
更新日期：1994-02-01 00:00:00
abstract：:The intrinsic cardiac responses to 2-months Nigella sativa (black seed) oral supplementation (800 mg/kg) in rats were investigated. The isolated hearts were perfused in a Langendorff preparation to demonstrate the effects of N. sativa on the baseline inotropic and chronotropic functions and the myocardial flow rate. N...
journal_title：International journal of cardiology
pub_type： 信件
doi：10.1016/j.ijcard.2007.07.075
更新日期：2009-01-24 00:00:00
abstract：OBJECTIVES:Systemic scleroderma (SSc) is a rare connective tissue disease presenting with fibrosis affecting skin and internal organs. Cardiovascular magnetic resonance (CMR) with quantification of extracellular volume (ECV) and T1 mapping might help to detect heart involvement. We aimed to evaluate whether myocardial ...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2017.08.072
更新日期：2017-12-15 00:00:00
abstract：:A 73 year old woman, with previous history of coronary artery bypass grafting, was admitted for refractory unstable angina. The angiography revealed a significant stenosis of the ostium of the left subclavian artery. The patient underwent successful stenting of the subclavian artery and remained symptom free until hos...
journal_title：International journal of cardiology
pub_type： 信件
doi：10.1016/j.ijcard.2007.04.145
更新日期：2008-07-21 00:00:00
abstract：:The analysis of post-exercise cardiac autonomic recovery is a practical clinical tool for the assessment of cardiovascular health. A reduced heart rate recovery - an indicator of autonomic dysfunction - has been found in a broad range of cardiovascular diseases and has been associated with increased risks of both card...
journal_title：International journal of cardiology
pub_type： 杂志文章,评审
doi：10.1016/j.ijcard.2016.10.057
更新日期：2017-01-15 00:00:00
abstract：:After more than two decades of AIDS epidemic, the spectrum of HIV-associated vascular diseases has mainly evolved from infectious and inflammatory vasculitides to premature atherosclerosis, its related contributing conditions (metabolic syndrome, dyslipidemia, insulin resistance syndrome) and complications (acute coro...
journal_title：International journal of cardiology
pub_type： 杂志文章,评审
doi：10.1016/j.ijcard.2008.11.113
更新日期：2009-04-17 00:00:00
abstract：:Increased lipid oxidative stress has been recently implicated in the pathogenesis of coronary artery spasm. Small, dense LDL with high susceptibility to oxidation may be linked to the genesis of coronary vasospasm. The relative migratory distance of the predominant densitometric peak of LDL from that of VLDL to that o...
journal_title：International journal of cardiology
pub_type： 临床试验,杂志文章
doi：10.1016/s0167-5273(02)00250-4
更新日期：2003-02-01 00:00:00
abstract：BACKGROUND:The purpose of this study was to evaluate prospectively the safety and efficacy of bovine thrombin injection for the treatment of iatrogenic post-catheterisation pseudoaneurysms. METHODS AND RESULTS:A total of 274 patients (90 women, 184 men, 69.8+/-7 years) with iatrogenic femoral pseudoaneurysms were trea...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2007.10.052
更新日期：2009-01-24 00:00:00
abstract：BACKGROUND:The mechanisms of antagonism vary between the angiotensin II type 1 receptor blockers (ARBs): insurmountable antagonism and surmountable antagonism. Recent retrospective observational studies suggest that ARBs may not have equivalent benefits in various clinical situations. The aim of this study was to compa...
journal_title：International journal of cardiology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.ijcard.2013.07.146
更新日期：2014-01-01 00:00:00
abstract：BACKGROUND:While the impact of mitral regurgitation (MR) prior to transcatheter aortic valve replacement (TAVR) has been intensively studied, the implications of post-procedural MR on outcome are unknown. We investigated the clinical and physiological impact of significant MR after TAVR. METHODS:Clinical and echocardi...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2019.07.092
更新日期：2020-01-15 00:00:00
