Abstract:
:We sought to investigate the relative clinical significance of target and nontarget lesions repeated percutaneous coronary intervention (re-PCI) in patients implanted with drug-eluting stents (DES). Out of 2626 consecutive DES patients, we retrospectively selected 166 (6.3%; 123 males, aged 65±10 years) who had a clinically-driven re-PCI over a mean follow-up of 15 months. Seventy-five patients (45%) underwent the second procedure for disease progression in nontarget lesions (nontarget lesion re-PCI group) while 91 (55%) showed target lesion in-stent restenosis or thrombosis (target lesion re-PCI group), with no significant intergroup difference in the temporal trends of re-PCI. The prevalence of stable coronary artery disease and acute coronary syndromes (ACS) was 22% and 78% in the target lesion re-PCI vs. 81% and 19% in the nontarget lesion re-PCI group (overall p<0.001), respectively. In-stent restenosis accounted for 75% of second procedures in the target lesion re-PCI group and presented as an ACS in 72% of cases. The need for a new PCI in DES patients is relatively low in a real world setting. Stent-related events in the target lesion and progression of disease in nontarget lesions account to a similar extent for re-PCI, although their clinical presentation is strikingly different. The most common presentation of events related to previously treated lesions is an unstable syndrome, which provides support to the concept that also restenosis in a DES should not be considered a clinically benign entity.
journal_name
Int J Cardioljournal_title
International journal of cardiologyauthors
Fineschi M,Zacà V,Gori T,Casini S,Sinicropi G,Pierli Cdoi
10.1016/j.ijcard.2009.11.049subject
Has Abstractpub_date
2010-11-19 00:00:00pages
322-324issue
2eissn
0167-5273issn
1874-1754pii
S0167-5273(09)01646-5journal_volume
145pub_type
信件abstract:BACKGROUND:Vascular wall remodeling is a major factor contributing to restenosis after angioplasty that involves migration and proliferation of vascular smooth muscle cells. The release of matrix-degrading metalloproteinases, including metalloproteinase-2 and metalloproteinase-9, facilitates remodeling. Experimental da...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/s0167-5273(03)00092-5
更新日期:2003-12-01 00:00:00
abstract::Takayasu's disease is an unusual arteritis that affects young females. Stroke is a common presenting symptom usually due to sudden occlusion of one or more thoracic aortic arch arteries. The author recommends prophylactic bypass of involved aortic arch arteries to prevent strokes. Abdominal aortic involvement causes s...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/s0167-5273(00)00179-0
更新日期:2000-08-31 00:00:00
abstract::To assess whether additional aneurysmectomy and/or bypass grafting influence prognosis we studied 97 patients with recurrent sustained monomorphic ventricular tachycardia after an old myocardial infarction. All patients underwent subendocardial resection due to drug-refractory ventricular tachycardia. There were 41 pa...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/0167-5273(92)90022-u
更新日期:1992-03-01 00:00:00
abstract::In cardiac surgery, postoperative low cardiac output has been shown to correlate with increased rates of organ failure and mortality. Catecholamines have been the standard therapy for many years, although they carry substantial risk for adverse cardiac and systemic effects, and have been reported to be associated with...
journal_title:International journal of cardiology
pub_type: 杂志文章,评审
doi:10.1016/j.ijcard.2015.02.022
更新日期:2015-04-01 00:00:00
abstract::Endothelial dysfunction induced by various atherosclerotic risk factors can initiate the process of atherosclerosis. Endothelial progenitor cells (EPCs), which have been considered as the precursor of endothelial cells (ECs), play an important role in the maintenance of endothelial function. The inverse association be...
journal_title:International journal of cardiology
pub_type: 杂志文章,评审
doi:10.1016/j.ijcard.2008.11.034
更新日期:2009-04-17 00:00:00
abstract:BACKGROUND:Uric acid stabilizes platelet aggregation and enhances thrombotic tendency. OBJECTIVE:To examine the relationship between raised serum uric acid and subsequent cardiovascular events (mortality, myocardial infarction, stroke). METHODS:This is a longitudinal study in a small random number (418) of patients i...
journal_title:International journal of cardiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0167-5273(99)00097-2
更新日期:1999-09-30 00:00:00
abstract::We present a case of a perforation of the saphenous vein graft during percutaneous angioplasty and its subsequent implantation with a polytetrafluoroethylene-covered stent. Angiographic as well as intravascular images of the site of perforation are provided. ...
journal_title:International journal of cardiology
pub_type: 信件
doi:10.1016/j.ijcard.2007.12.053
更新日期:2009-05-01 00:00:00
abstract:BACKGROUND:The role of programmed ventricular stimulation (PVS) in patients with idiopathic dilated cardiomyopathy (DCM) and syncope receiving implantable cardioverter-defibrillators (ICD) remains controversial. METHODS AND RESULTS:Between 1994 and July 2002, 20 patients with DCM and syncope underwent PVS and ICD impl...
journal_title:International journal of cardiology
pub_type: 杂志文章,多中心研究,评审
doi:10.1016/j.ijcard.2003.12.012
更新日期:2005-02-28 00:00:00
abstract::Mycobacterium tuberculosis (TB) is a major cause of death globally. TB is capable of infecting every organ in the body, and the heart is no exception. Tuberculous endocarditis (TBE) was first reported in 1892 and subsequently many other cases have been described, highlighting the significant morbidity and mortality as...
journal_title:International journal of cardiology
pub_type: 杂志文章,评审
doi:10.1016/j.ijcard.2012.08.009
更新日期:2013-08-10 00:00:00
abstract::Left ventricular outflow tract obstruction caused by a discrete subaortic membrane in a young female was successfully dilated using an Inoue balloon catheter. The Inoue balloon catheter was used in a retrograde manner via the femoral artery. ...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/0167-5273(96)02579-x
更新日期:1996-04-19 00:00:00
abstract:BACKGROUND:Angiopoietin-2 (Angpt2) has been implicated in the mediation and regulation of angiogenesis and inflammation which are believed to be critical mechanisms in the pathogenesis of both abdominal aortic aneurysm (AAA) and cardiovascular events. The aim of this study was to assess whether serum Angpt2 was associa...
journal_title:International journal of cardiology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ijcard.2012.03.120
更新日期:2013-08-20 00:00:00
abstract::Increased lipid oxidative stress has been recently implicated in the pathogenesis of coronary artery spasm. Small, dense LDL with high susceptibility to oxidation may be linked to the genesis of coronary vasospasm. The relative migratory distance of the predominant densitometric peak of LDL from that of VLDL to that o...
journal_title:International journal of cardiology
pub_type: 临床试验,杂志文章
doi:10.1016/s0167-5273(02)00250-4
更新日期:2003-02-01 00:00:00
abstract:INTRODUCTION:Sports activity has been associated with the development of atrial arrhythmias. Atrial fibrillation (AF) is frequently observed after successful ablation for atrial flutter. Sports activity as a risk factor for AF development after flutter ablation has not been studied. METHODS:We analyzed outcome in 137 ...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2005.02.043
更新日期:2006-02-08 00:00:00
abstract:BACKGROUND:Hypertension is a major cause of cardiovascular disease. Periodic nationwide surveys are essential for monitoring secular trend of hypertension and its control in population. We assessed prevalence of hypertension and related awareness, treatment and control rates in Chinese adults in 2013-14. METHODS:A nat...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2016.10.110
更新日期:2017-01-15 00:00:00
abstract::A 13-year-old black male who died suddenly as a result of atresia of the left coronary ostium and left main coronary artery is presented. An association between this anomaly and supravalvar aortic stenosis is observed. The literature is reviewed and 14 similar cases are compared. Presentation of this anomaly is variab...
journal_title:International journal of cardiology
pub_type: 杂志文章,评审
doi:10.1016/0167-5273(89)90284-2
更新日期:1989-03-01 00:00:00
abstract::In 24 subjects presenting with apparently idiopathic ventricular arrhythmias, a final diagnosis of arrhythmogenic right ventricular cardiomyopathy was formulated following global evaluation of the clinical, cross-sectional echocardiography and angiographic findings, and the observation of myocardial atrophy with fibro...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/0167-5273(92)90177-5
更新日期:1992-05-01 00:00:00
abstract:BACKGROUND:The prevalence of coronary artery disease (CAD) among Bangladeshis greatly exceeds that of Caucasians. Bangladeshis also suffer from premature onset, clinically aggressive and angiographically extensive disease. The role of conventional CAD risk factors (CCRFs) has been questioned. We therefore sought to det...
journal_title:International journal of cardiology
pub_type: 信件
doi:10.1016/j.ijcard.2008.12.175
更新日期:2011-01-21 00:00:00
abstract::Spontaneous coronary artery dissection (SCAD) causing acute myocardial infarction is a rare event. It occurs mostly in young women without traditional risk factors for coronary artery disease, particularly during the peripartum period. We describe two occurrences of SCAD in young women in whom coronary atherosclerosis...
journal_title:International journal of cardiology
pub_type: 信件
doi:10.1016/j.ijcard.2005.12.021
更新日期:2007-01-31 00:00:00
abstract::Isolated subvalvular pulmonary stenosis (ISPS) is a rare condition, and it is often accompanied by hypertrophic cardiomyopathy. However, diagnosis of ISPS is obscure because of difficulty in comprehension of three-dimensional cardiac anatomy. Whole-heart magnetic resonance imaging (MRI) is a new, totally non-invasive ...
journal_title:International journal of cardiology
pub_type: 信件
doi:10.1016/j.ijcard.2007.05.106
更新日期:2009-01-09 00:00:00
abstract:BACKGROUND:To determine the impact of circulating miRNA and protein activity on the severity of ascending aortic dilatation in patients with bicuspid (BAV) and tricuspid aortic valve (TAV). METHODS:By reverse transcription polymerase chain reaction, exosomal circulating expression levels (versus healthy aorta) of miRN...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2018.10.005
更新日期:2018-12-15 00:00:00
abstract::Drug-eluting stent (DES) and bare metal stent (BMS) are effective treatments for preventing vascular disease, but whether using DES is associated with positive clinical outcomes compared with BMS in patients with saphenous vein graft disease (SVGD) has not been established. Three electronic databases including PubMed,...
journal_title:International journal of cardiology
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.ijcard.2016.07.001
更新日期:2016-11-01 00:00:00
abstract:BACKGROUND:This study aimed to evaluate real-world clinical outcome of patients needing short dual antiplatelet therapy (S-DAPT) following PCI with Ultimaster® thin-strut, biodegradable polymer sirolimus-eluting stent (BP-SES), which was supposed to induce faster stent endothelialization and reduce device thrombogenici...
journal_title:International journal of cardiology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ijcard.2019.03.030
更新日期:2019-09-01 00:00:00
abstract:BACKGROUND:Long duration of diabetes mellitus (DM) is associated with an increased risk of infection, however no studies have yet focused on the duration of DM and the associated risk of infective endocarditis (IE). METHODS:Patients with DM were identified through the Danish Prescription Registry, 1996-2015. Duration ...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2018.09.106
更新日期:2019-03-01 00:00:00
abstract:BACKGROUND:Whereas the relationship between subclinical atherosclerosis and antiphospholipid syndrome (APS) has been widely investigated, little is known about subclinical atherosclerosis in asymptomatic carriers with isolated antiphospholipid antibodies positivity (APP). METHODS:Consecutive APP carriers, APS subjects...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2018.06.010
更新日期:2019-01-01 00:00:00
abstract:UNLABELLED:The purpose of this study was to determine the accuracy of percussion of the left cardiac border. Sixty-six adult patients were studied. The left cardiac border as determined by percussion and marked with a calibrated lead marker was compared with that obtained by a chest X-ray. The error in locating the lef...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/0167-5273(92)90267-7
更新日期:1992-12-01 00:00:00
abstract:BACKGROUND:Isolated ventricular noncompaction is considered to predominantly affect the left ventricle. It is characterized by increased left ventricular wall thickness and deep intertrabecular recesses with to-and-fro blood flow that remains in continuity with the ventricular flow. Aim of the study was to present a gr...
journal_title:International journal of cardiology
pub_type: 信件
doi:10.1016/j.ijcard.2009.05.062
更新日期:2010-11-05 00:00:00
abstract::Pregnancy can precipitate cardiac arrhythmias not previously present in seemingly well individuals. Risk of arrhythmias is relatively higher during labor and delivery. Potential factors that can promote arrhythmias in pregnancy and during labor and delivery include the direct cardiac electrophysiological effects of ho...
journal_title:International journal of cardiology
pub_type: 杂志文章,评审
doi:10.1016/s0167-5273(02)00601-0
更新日期:2003-04-01 00:00:00
abstract:BACKGROUND:A correct measurement of the QT interval in the out-of-hospital setting is important whenever the long QT syndrome (LQTS) is suspected or a therapy might lead to drug-induced LQTS (diLQTS) because QT interval monitoring in the initial days of therapy could alert to dangerous QT prolongation. We explored whet...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2018.03.097
更新日期:2018-09-01 00:00:00
abstract:BACKGROUND:The definitive role of phosphatidylserine (PS) in the prothrombotic state of non-valvular atrial fibrillation (NVAF) remains unclear. Our objectives were to study the PS exposure on blood cells and microparticles (MPs) in NVAF, and evaluate their procoagulant activity (PCA). METHODS:NVAF patients without (n...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2018.01.116
更新日期:2018-05-01 00:00:00
abstract::This article has been withdrawn at the request of the editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy. ...
journal_title:International journal of cardiology
pub_type: 杂志文章,收录出版
doi:10.1016/j.ijcard.2008.12.002
更新日期:2009-01-10 00:00:00