当前位置： SCI文献检索 > INTERNATIONAL JOURNAL OF CARDIOLOGY期刊下所有文献 > Gender-related differences in patients with acute heart failure: management and predictors of in-hospital mortality.

Gender-related differences in patients with acute heart failure: management and predictors of in-hospital mortality.

Abstract：

AIM AND METHODS:Gender-related differences in clinical phenotype, in-hospital management and prognosis of acute heart failure (AHF) patients have been previously reported in European and US registries. The ALARM-HF survey is the first to include a cohort of 4953 patients hospitalized for AHF in 666 hospitals in 6 European countries, Mexico and Australia. RESULTS:Women accounted for 37% of the study population, were older and had higher rates of de novo heart failure (45% vs 36%, p<0.001) than men. An acute coronary syndrome (ACS) was the predominant precipitating factor in both genders, but to a lesser extent in females (30% vs 42%, p<0.001). Between genders comparison showed higher incidence of atrial fibrillation, valvular heart disease, diabetes, obesity, anemia and depression in women (p<0.05). Similarly, women had higher left ventricular ejection fraction (LVEF) on admission (42 ± 15% vs 36 ± 13%, p<0.001) and systolic blood pressure (135 ± 40 mm Hg vs 131 ± 39 mm Hg, p=0.001) than men. On the other hand, men had more often coronary artery disease, renal failure and chronic obstructive pulmonary disease (p<0.05). Importantly, in-hospital mortality was similar in both genders (11.1% in females vs 10.5% in males, p=0.475), and its common predictors were: systolic blood pressure at admission, creatinine>1.5mg/dL and diabetes. Furthermore, recent ACS, valvular heart disease and dementia contributed to prognosis in women, while LVEF, hypertension and anemia were independent predictors in men. CONCLUSION:Among patients with AHF, there are significant differences in co-morbidities, precipitating factors and predictors of in-hospital mortality between genders. Nevertheless, in-hospital mortality remains similar between genders.

journal_name

Int J Cardiol

journal_title

International journal of cardiology

authors

Parissis JT,Mantziari L,Kaldoglou N,Ikonomidis I,Nikolaou M,Mebazaa A,Altenberger J,Delgado J,Vilas-Boas F,Paraskevaidis I,Anastasiou-Nana M,Follath F

doi

10.1016/j.ijcard.2012.09.096

subject

Has Abstract

pub_date

2013-09-20 00:00:00

pages

185-9

issue

eissn

0167-5273

issn

1874-1754

pii

S0167-5273(12)01202-8

journal_volume

168

pub_type

杂志文章

在线工具

Gender-related differences in patients with acute heart failure: management and predictors of in-hospital mortality.