Abstract:
:The practice of gynecological surgery is being reshaped by commercial interests that are promoting the use of trochar-and-mesh surgical kits for the treatment of stress incontinence and pelvic organ prolapse. In this article, we review the recent history of these surgical innovations and discuss the implications of changes in surgical practice that are driven by commercial interests of this kind. We situate this phenomenon within the general "life cycle" of surgical innovation and point out the dangers inherent in the adoption of new procedures without adequate evidence to support their safety and efficacy. We highlight the ethical responsibilities surgeons and their professional organizations have in making sure such innovations are safe and effective before they come into widespread use. Finally, we offer some policy suggestions to ensure that this process has proper oversight.
journal_name
Am J Obstet Gynecoljournal_title
American journal of obstetrics and gynecologyauthors
Wall LL,Brown Ddoi
10.1016/j.ajog.2009.05.031subject
Has Abstractpub_date
2010-01-01 00:00:00pages
30.e1-4issue
1eissn
0002-9378issn
1097-6868pii
S0002-9378(09)00539-0journal_volume
202pub_type
杂志文章abstract:OBJECTIVE:The goal of the study was to examine risks in pregnancy in patients with Ebstein anomaly. STUDY DESIGN:Data were examined retrospectively for 13 patients (27 pregnancies, 21 live births) with Ebstein anomaly during pregnancy who were treated at our institution from 1985 to 2011. The associated anomalies in t...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/j.ajog.2013.07.005
更新日期:2013-11-01 00:00:00
abstract::A total of 1,996 direct fetal heart rate (FHR) tracings in labor were analyzed using the first and last 30 minutes of monitoring in order to evaluate individual FHR characteristics as to their ability to predict the fetal status. Comparisons were made between individual FHR characteristics occurring alone ("uncomplica...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/0002-9378(79)90113-3
更新日期:1979-04-01 00:00:00
abstract:OBJECTIVE:The physiopathology of preeclampsia is still unclear, but an imbalance between reactive oxygen species (ROS) and antioxidants, also called oxidative stress, appears to be an important contributing factor. The ROS promote lipid oxidation and are known to induce stress proteins, such as hemeoxygenase 1 (HO-1) a...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/j.ajog.2008.12.031
更新日期:2009-05-01 00:00:00
abstract:OBJECTIVE:Our purpose was to determine whether postterm patients with oligohydramnios differ in their fetal and umbilical blood flow distribution from those with a normal volume of amniotic fluid. STUDY DESIGN:Pulsed-wave Doppler imaging was used prospectively to determine the resistance index in the fetal middle cere...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/0002-9378(95)90276-7
更新日期:1995-08-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to investigate the vascular function of pregnant women with insulin-dependent diabetes mellitus, using a noninvasive method. STUDY DESIGN:This was a cross-sectional study that examined vascular function, which was assessed by flow-mediated dilatation of the brachial artery, in 3...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1067/mob.2002.119111
更新日期:2002-01-01 00:00:00
abstract::This study compares fetal corticoid response from conventional dose (12.0 mg) intramuscular betamethasone to large dose (1,000 mg) intravenous cortisol administered to women in premature labor for acceleration of fetal lung maturity. To compare these two regimens, 14 women selected at random were treated in groups of ...
journal_title:American journal of obstetrics and gynecology
pub_type: 临床试验,杂志文章
doi:10.1016/0002-9378(76)90172-1
更新日期:1976-03-01 00:00:00
abstract:OBJECTIVE:Our purpose was to determine whether cultured human decidual cells produce chemokines in response to different strains of group B streptococci and purified bacterial cell wall components. STUDY DESIGN:Human decidual cells were cultured from term placentas by standard techniques. Different strains of group B ...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/s0002-9378(97)70162-5
更新日期:1997-09-01 00:00:00
abstract:OBJECTIVES:The purpose of our study was to investigate the combined interactive effects of maternal age, parity, and smoking on pregnancy outcome. STUDY DESIGN:This was a population-based Swedish study (n = 538,829). RESULTS:Multiple logistic regression analysis showed that the smoking-related effect on the relative ...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/s0002-9378(12)90878-9
更新日期:1993-01-01 00:00:00
abstract::Engaging women in discussions about reproductive goals in health care settings is increasingly recognized as an important public health strategy to reduce unintended pregnancy and improve pregnancy outcomes. "Reproductive life planning" has gained visibility as a framework for these discussions, endorsed by public hea...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/j.ajog.2016.10.004
更新日期:2017-02-01 00:00:00
abstract:OBJECTIVE:Our purpose was to examine the hypothesis that the relaxant response to corticotropin-releasing factor is endothelium dependent and changes during pregnancy. STUDY DESIGN:Relaxant responses to cumulative concentrations of corticotropin-releasing hormone were measured in rings of thoracic aorta, precontracted...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/s0002-9378(97)80042-7
更新日期:1997-01-01 00:00:00
abstract::Cuba has a comprehensive National Health System which delivers primary and secondary health care to 100% of the population. Communicable disease control and preventive medicine programs are implemented through this System. The National Syphilis Control Program is described briefly as an example of a successful control...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/0002-9378(80)91112-6
更新日期:1980-12-01 00:00:00
abstract::We studied differences in the role of genetic factors in prematurity and intrauterine growth retardation with the use of data on 312 Amish singleton live children ascertained from Amish records in Lancaster county, Pennsylvania, between 1969 and 1980. Birth and death certificates were obtained on all children, and inb...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/s0002-9378(87)80181-3
更新日期:1987-08-01 00:00:00
abstract:OBJECTIVE:We hypothesized that glycodelin stimulates vascular endothelial growth factor (VEGF) expression in response to oxidative stress. STUDY DESIGN:EM42 (human endometrial epithelial cell line) and primary endometrial epithelial cells were subjected to oxidative stress with minimally oxidized low density lipoprote...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/j.ajog.2006.07.025
更新日期:2006-12-01 00:00:00
abstract:OBJECTIVE:Our purpose was to review our results of multimodality treatment of lymph node metastasis in endometrial cancer (stage IIIC). STUDY DESIGN:All patients underwent surgical staging for endometrial cancer with complete pelvic and aortic lymphadenectomy. All macroscopic nodal metastases were resected. Patients w...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1067/mob.2001.115225
更新日期:2001-05-01 00:00:00
abstract::To determine the microbiologic etiology of acute salpingitis, laparoscopy was used in 26 patients to obtain specimens for a variety of microorganisms directly from the fallopian tube. Simultaneous culdocentesis was performed to obtain peritoneal fluid for microbiologic analysis. A variety of microorganisms were isolat...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/0002-9378(79)90798-1
更新日期:1979-05-01 00:00:00
abstract:OBJECTIVE:Our purpose was to improve the accuracy of prenatal prognostication by directly correlating obstetric ultrasonographic measurements with neonatal survival. STUDY DESIGN:We studied 130 singleton live-born infants with birth weights between 500 and 1000 gm and who underwent complete ultrasonographic examinatio...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/0002-9378(93)90606-j
更新日期:1993-09-01 00:00:00
abstract::This study compares associated high-risk factors and perinatal outcome between 273 symmetric and 445 asymmetric infants with intrauterine growth retardation. No differences were seen in 17 obstetric, medical, and environmental-behavioral high-risk factors between symmetric and asymmetric intrauterine growth retardatio...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/0002-9378(91)91433-w
更新日期:1991-06-01 00:00:00
abstract::Seventeen pregnant rabbits were studied under conscious, unstressed conditions after catheterization of the right ventricle (RV), a femoral artery (A), and a uterine vein (UV). Respiratory gas tensions, pH, and oxygen saturations and contents were determined serially throughout the latter half of gestation. The uterin...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/s0002-9378(85)80054-5
更新日期:1985-07-15 00:00:00
abstract::Physicians who deliver babies in Alabama were surveyed to determine their level of knowledge about the survival of low--birth weight/early gestational age infants. These estimates of neonatal survival were compared to the actual neonatal survival rates at local hospitals and at the regional perinatal centers in Alabam...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/0002-9378(82)90114-4
更新日期:1982-07-15 00:00:00
abstract::Serum progesterone was assayed by the competitive protein-binding technique in 20 cases of gestational choriocarcinoma and one case of nongestational choriocarcinoma. Serum human chorionic gonadotropin (HCG) was simultaneously measured from the same blood samples by the hemagglutination-inhibition technique. Serum pro...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/0002-9378(75)90503-7
更新日期:1975-12-01 00:00:00
abstract::Norinyl 1+50 oral contraceptive pills contain 1 mg of the progestin, norethindrone, and .05 mg (or 50 mcg) of the estrogen, mestranol. These pills can either be taken in 21-day or 28-day therapy cycles. This dosage is low but effective. Oral contraception is supposed to prevent pregnancy by suppressing ovulation and ...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1973-01-01 00:00:00
abstract::Significant public health disparities exist surrounding teen and unplanned pregnancy in the United States. Women of color and those with lower education and socioeconomic status are at much greater risk of unplanned pregnancy and the resulting adverse outcomes. Unplanned pregnancies reduce educational and career oppor...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章,评审
doi:10.1016/j.ajog.2016.02.017
更新日期:2016-06-01 00:00:00
abstract:OBJECTIVE:This study was designed to evaluate the uterine vascular responses to endothelin-1 in pregnant and estrogen-treated nonpregnant sheep. STUDY DESIGN:Seven pregnant and five nonpregnant oophorectomized ewes received local uterine artery infusions of endothelin-1, norepinephrine, and phenylephrine. Arterial blo...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/0002-9378(92)91755-y
更新日期:1992-12-01 00:00:00
abstract::Twenty-three postmenopausal women with a median of 2 years past menopause (range, 1 to 12 years) and a median age of 52 years (range, 39 to 62 years) were recruited to participate in a longitudinal study designed to investigate the factors that influence the increase in bone density with subcutaneous estradiol and tes...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/0002-9378(90)90608-a
更新日期:1990-11-01 00:00:00
abstract::The kinetics of prostaglandins instilled vaginally has been studied in the maternal and fetal circulations, with observation of changes in the stable prostaglandin E2 metabolite 11-deoxy-13,14-dihydro-15-keto-11 beta,16-cyclo-prostaglandin E2. After the administration of prostaglandin E2, 10 mg in a wax-based pessary,...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/0002-9378(89)90752-7
更新日期:1989-10-01 00:00:00
abstract:BACKGROUND:The established method of screening for preeclampsia is to identify risk factors from maternal demographic characteristics and medical history; in the presence of such factors the patient is classified as high risk and in their absence as low risk. However, the performance of such an approach is poor. We dev...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/j.ajog.2018.11.1087
更新日期:2019-02-01 00:00:00
abstract:BACKGROUND:There is a marked increase in the use of selective serotonin reuptake inhibitors and serotonin norepinephrine reuptake inhibitors in the last decade. Many newborns are likely to be exposed during pregnancy and labor. OBJECTIVE:We aimed to evaluate the association between exposure to selective serotonin reup...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章,meta分析
doi:10.1016/j.ajog.2018.08.030
更新日期:2019-01-01 00:00:00
abstract:OBJECTIVE:Review alternative approaches to oral metronidazole for the treatment of bacterial vaginosis. STUDY DESIGN:Assessment of clinical trials on the treatment of bacterial vaginosis with regimens other than 5 to 7 days of metronidazole. RESULTS:Single-dose metronidazole, 2 gm orally, is as effective as 5- to 7-d...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章,评审
doi:10.1016/0002-9378(93)90346-k
更新日期:1993-08-01 00:00:00
abstract:OBJECTIVE:This study was undertaken to evaluate the levels of matrix metalloproteinase 2 (MMP-2) in the precursors lesions and in the invasive cervical carcinoma and to quantify the immune reactive expression of MMP-2, using MMP-2 immunohistochemistry, in intraepithelial cervical neoplasias and in the invading cervical...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/j.ajog.2003.12.017
更新日期:2004-05-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to estimate the prevalence and impact upon quality of life of anal incontinence (AI) in women aged 18 to 65. STUDY DESIGN:Consecutive women presenting for general gynecologic care were given a bowel function questionnaire. Women with AI were prompted to complete the Fecal Incont...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ajog.2004.11.030
更新日期:2005-05-01 00:00:00