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Risk factors for maternal and fetal outcome in pregnancy complicated by Ebstein anomaly.

Abstract：

OBJECTIVE:The goal of the study was to examine risks in pregnancy in patients with Ebstein anomaly. STUDY DESIGN:Data were examined retrospectively for 13 patients (27 pregnancies, 21 live births) with Ebstein anomaly during pregnancy who were treated at our institution from 1985 to 2011. The associated anomalies in these patients were atrial septal defect (ASD) (n = 4) and the Wolff-Parkinson-White syndrome (n = 6). RESULTS:Before pregnancy, 2 patients underwent ASD closure and 1 received tricuspid valve replacement (TVR). In all patients, the cardiothoracic ratio increased from 55.1 at conception to 57.0 during pregnancy and 58.0 postpartum (P < .05). Cesarean sections were performed in 3 cases: 1 with ventricular tachycardia and orthopnea (New York Heart Association [NYHA] III) preterm; at full term, and the third in a patient with a mechanical tricuspid valve who developed maternal cerebellum hemorrhage at 27 weeks. The baby died of prematurity in the third case. In all other cases (20 of 21), neonatal prognoses were good without congenital heart diseases. There were 6 spontaneous abortions. Recurrent paroxysmal supraventricular tachycardia occurred during pregnancy in 2 cases and was treated with adenosine triphosphate or verapamil. In 17 pregnancies, NYHA remained in class I and all had full-term vaginal delivery. CONCLUSION:Maternal and fetal outcomes are good in patients with Ebstein anomaly and NYHA class I. However, pregnancy in Ebstein anomaly can be complicated with tachyarrhythmia or cardiac failure. In post-TVR cases, meticulous care is required for these complications during pregnancy and delivery.

journal_name

Am J Obstet Gynecol

journal_title

American journal of obstetrics and gynecology

authors

Katsuragi S,Kamiya C,Yamanaka K,Neki R,Miyoshi T,Iwanaga N,Horiuchi C,Tanaka H,Yoshimatsu J,Niwa K,Ikeda T

doi

10.1016/j.ajog.2013.07.005

subject

Has Abstract

pub_date

2013-11-01 00:00:00

pages

452.e1-6

issue

5

eissn

0002-9378

issn

1097-6868

pii

S0002-9378(13)00714-X

journal_volume

209

pub_type

杂志文章

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