Macrophage activation syndrome in malaria.

Abstract:

:Macrophage activation syndrome (MAS) is a clinical syndrome caused by an excessive proliferation of T lymphocytes and well-differentiated macrophages; an entity distinct from malignant histiocytosis. Although rheumatologic conditions are the common cause of MAS, a wide range of infections are also seen to cause MAS. We report an adolescent with severe Plasmodium falciparum malaria and MAS. He fulfilled six out of eight criteria required to diagnose hemophagocytic lymphohistiocytosis.

journal_name

Rheumatol Int

authors

Dass R,Barman H,Duwarah SG,Choudhury V,Jain P,Deka NM,Murari M

doi

10.1007/s00296-009-1033-1

subject

Has Abstract

pub_date

2010-06-01 00:00:00

pages

1099-101

issue

8

eissn

0172-8172

issn

1437-160X

journal_volume

30

pub_type

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