Seminal vesicle invasion in prostate cancer: prediction with combined T2-weighted and diffusion-weighted MR imaging.

Abstract:

:The aim of this study was to evaluate the usefulness of diffusion-weighted imaging (DWI) in detecting seminal vesicle invasion (SVI). A total of 283 patients underwent conventional MRI and DWI before prostate cancer surgery. The apparent diffusion coefficient (ADC) values of all PCa foci, SVI and seminal vesicle were measured. T2 images alone and then T2 images combined with DWI were scored for the likelihood of SVI. The area under the receiver operating characteristic curve (AUC) was used to assess accuracy. Statistical significance was inferred at P < 0.05. On pathological analysis, 39 patients had SVI. The ADC values of SVI were significantly lower than those of SV. The AUC for T2-weighted imaging plus DW imaging (0.897) was significantly larger (P < 0.05) than that for T2-weighted imaging alone (0.779). T2 images combined with DWI shows significantly higher accuracy than T2-weighted imaging alone in the detection of SVI.

journal_name

Eur Radiol

journal_title

European radiology

authors

Ren J,Huan Y,Wang H,Ge Y,Chang Y,Yin H,Sun L

doi

10.1007/s00330-009-1428-0

subject

Has Abstract

pub_date

2009-10-01 00:00:00

pages

2481-6

issue

10

eissn

0938-7994

issn

1432-1084

journal_volume

19

pub_type

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