Impression cytology features of conjunctival nevi reported as more noticeable.

Abstract:

PURPOSE:To report the impression cytology features of conjunctival nevi reported as more noticeable. METHODS:35 patients who reported that a conjunctival lesion had become more noticeable after color or size change were enrolled. On slit-lamp examination, a clinical diagnosis of nevus was made and lesions underwent impression cytology using acetate cellulose strips and a combined staining with PAS, H&E and Papanicolaou. At patient's or parents' request, excision of the lesion was performed and the tissue was submitted to histopathological study. RESULTS:Impression cytology examination revealed nests or cluster of nevus cells within the epithelium layer containing or not mucous-secreting goblet cells in 32 cases (91.4%). Ten patients (28.5%) had the tumor removed and histopathological diagnosis was compound nevus in 8 eyes (1 from caruncle, 1 from plica semilunaris and 6 from bulbar conjunctiva) and subepithelial nevus from bulbar conjunctiva (2 eyes). CONCLUSION:Optical microscopy analysis of the impression cytology specimens confirmed the clinical diagnosis by demonstrating typical histopathological features of the superficial layers from conjunctival nevi in 91.4% of the cases. For amelanotic nevi IC can also allow a differential diagnosis from other nonpigmented lesions. The technique does not replace histopathological examination, but additionally, may assist in evaluating nevus cells in children and adults.

journal_name

Arq Bras Oftalmol

authors

Barros Jde N,Lowen MS,Mascaro VL,Andrade TP,Martins MC

doi

10.1590/s0004-27492009000200014

subject

Has Abstract

pub_date

2009-03-01 00:00:00

pages

205-10

issue

2

eissn

0004-2749

issn

1678-2925

pii

S0004-27492009000200014

journal_volume

72

pub_type

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