Abstract:
PURPOSE:Toxoplasmosis is the most common cause of posterior infectious uveitis worldwide. It is often impossible to determine its congenital or acquired nature. Interleukin-2 (IL-2) in peripheral blood has been described as a possible marker for acquired toxoplasmosis. The purpose of this study is to evaluate the histopathological characteristics of ocular toxoplasmosis cases using CD25 as a marker for the expression of interleukin-2. METHODS:Ten formalin-fixed, paraffin-embedded enucleated globes from ten immunocompetent patients with clinical diagnosis of toxoplasmosis were evaluated. Four patients had the acquired form of ocular toxoplasmosis (positive IgM) while six were IgM negative and IgG positive for toxoplasmosis. Histopathological slides were reviewed for the extension of the retinal necrosis, number of toxo cysts, the granulomatous inflammatory reaction, the presence of T and B cells within the choroid and the IL-2 expression. Immunohistochemistry using monoclonal antibodies was performed to observe the expression of CD4, CD8, CD20, CD25, and CD68. RESULTS:The histopathological evaluation disclosed no differences between acquired and the other ocular toxoplasmosis cases regarding the characteristics studied. However, CD25 showed a higher expression of IL-2 on the 4 acquired cases of ocular toxoplasmosis compared to the remainders. CONCLUSIONS:To the best of our knowledge, this is the first report showing that the use of CD25 as a marker for interleukin-2 could differentiate acquired ocular toxoplasmosis.
journal_name
Arq Bras Oftalmoljournal_title
Arquivos brasileiros de oftalmologiaauthors
Miyamoto C,Mattos Neto RB,Cesare SD,Belfort Junior R,Burnier MN Jrdoi
10.1590/s0004-27492010000500011subject
Has Abstractpub_date
2010-09-01 00:00:00pages
443-6issue
5eissn
0004-2749issn
1678-2925pii
S0004-27492010000500011journal_volume
73pub_type
杂志文章abstract:PURPOSES:To evaluate the retina nerve fiber layer by laser polarimetry in patients in chronic use of chloroquine. METHODS:Forty-four eyes of twenty-two patients were studied. These were in use of chloroquine due to rheumatic diseases during at least one year. As a control group, twenty patients without use of chloroqu...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.1590/s0004-27492005000200008
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abstract:PURPOSE:To assess the long-term refractive outcomes of photorefractive keratectomy in myopia and myopic astigmatism. METHODS:A retrospective study of 120 photorefractive keratectomy operated eyes with at least four-year follow-up (maximum of 96 months, mean follow-up 55 months). We divided patients into group 1 (G1) s...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.1590/s0004-27492007000600017
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abstract:PURPOSE:To compare the preferential hyperacuity perimeter (Preview PHP; Carl Zeiss Meditec, Dublin, CA) with the original Amsler grid in the detection of choroidal neovascularization (CNV) in patients with age-related macular degeneration (AMD). METHODS:Patients were classified into groups, based on the severity of th...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.1590/s0004-27492007000500009
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abstract:PURPOSE:The aim of this study was to establish the frequency of refractive errors in children and adolescents aged between 8 and 17 years old, living in the metropolitan area of Bucaramanga (Colombia). METHODS:This study was a secondary analysis of two descriptive cross-sectional studies that applied sociodemographic ...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
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abstract::Ocular inflammation is one of the leading causes of blindness and loss of vision. Human uveitis is a complex and heterogeneous group of diseases characterized by inflammation of intraocular tissues. The eye may be the only organ involved, or uveitis may be part of a systemic disease. A significant number of cases are ...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章,评审
doi:10.1590/s0004-27492012000200016
更新日期:2012-03-01 00:00:00
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journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.1590/s0004-27492008000700009
更新日期:2008-11-01 00:00:00
abstract:PURPOSE:To analyze the benefits after cataract surgery in professional activities. METHODS:A prospective, randomized study was conducted at the Clinical Hospital of the University of São Paulo. The patients had cataract surgery by phacoemulsification (PHACO) and by extracapsular extraction (EECP). RESULTS:The sample ...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章,随机对照试验
doi:10.1590/s0004-27492010000600003
更新日期:2010-11-01 00:00:00
abstract:PURPOSE:To compare the measurement of the palpebral fissure done either manually and by computer analysis of image of individuals without lid alterations. METHODS:One hundred two palpebral fissures from 51 normal subjects have been analyzed. The patients' age ranged from 17 to 84 years, with 25 (49%) males and 26 (51%...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.1590/s0004-27492005000600014
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journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.1590/s0004-27492007000400014
更新日期:2007-07-01 00:00:00
abstract::A 43-year-old male with a history of eosinophilic angiocentric fibrosis presented with headache and double vision since 48 h. Idiopathic hypertrophic pachymeningitis was diagnosed based on nuclear magnetic resonance and comprehensive systemic study findings. Eosinophilic angiocentric fibrosis and idiopathic hypertroph...
journal_title:Arquivos brasileiros de oftalmologia
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更新日期:2018-06-01 00:00:00
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doi:10.5935/0004-2749.20200032
更新日期:2020-06-01 00:00:00
abstract:PURPOSES:To evaluate changes in ocular blood flow and subfoveal choroidal thickness in patients with symptomatic carotid artery stenosis after carotid artery stenting. METHODS:We included 15 men (mean age, 63.6 ± 9.1 years) with symptomatic carotid artery stenosis and 18 healthy volunteers (all men; mean age, 63.7 ± 5...
journal_title:Arquivos brasileiros de oftalmologia
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abstract:PURPOSE:To evaluate the ophthalmic artery hemodynamics in patients with chronic heart failure. METHODS:Doppler parameters of ophthalmic artery of 18 patients with chronic heart failure in different stages of the disease were compared with 21 healthy volunteers (control group). These parameters were also correlated wit...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.1590/s0004-27492011000500003
更新日期:2011-09-01 00:00:00
abstract:PURPOSE:To describe an outbreak of Pseudomonas aeruginosa endophthalmitis post cataract surgery. Clinical findings, treatment and outcome are discussed. METHODS:Clinical charts review of forty-five patients treated for endophthalmitis in a two-day period. The patients underwent primary vitrectomy, anterior chamber irr...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
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journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.5935/0004-2749.20150062
更新日期:2015-07-01 00:00:00
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journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.1590/s0004-27492005000400019
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abstract:PURPOSE:To report the retrospective experience of a reference center in the diagnosis and treatment of orbital eosinophilic granuloma. METHODS:A review of the files in the Opththalmic Pathology Laboratory, of the Hospital Universitário Professor Edgard Santos, Universidade Federal da Bahia, between 1974 and 2004, was ...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.1590/s0004-27492008000300019
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journal_title:Arquivos brasileiros de oftalmologia
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journal_title:Arquivos brasileiros de oftalmologia
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journal_title:Arquivos brasileiros de oftalmologia
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journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.1590/s0004-27492008000100013
更新日期:2008-01-01 00:00:00
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journal_title:Arquivos brasileiros de oftalmologia
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journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.5935/0004-2749.20180040
更新日期:2018-06-01 00:00:00
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journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章,多中心研究
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journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.1590/s0004-27492008000300028
更新日期:2008-05-01 00:00:00
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journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.1590/s0004-27492011000200012
更新日期:2011-03-01 00:00:00
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journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.5935/0004-2749.20160089
更新日期:2016-09-01 00:00:00
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journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.5935/0004-2749.20200091
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abstract:PURPOSE:To evaluate the effect of intravitreal triamcinolone acetonide in patients with diffuse diabetic macular edema on the visual acuity and intraocular pressure. To report the potential adverse events and to analyze the potential relationship between age and visual acuity and intraocular pressure variability. METH...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.1590/s0004-27492010000200006
更新日期:2010-03-01 00:00:00
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journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章,meta分析,评审
doi:10.1590/s0004-27492008000600027
更新日期:2008-11-01 00:00:00