Abstract:
BACKGROUND:Many studies have demonstrated that the specific method of wound dressing used may affect the healing process. However, the effect of the method of wound dressings on the expression of growth factors is not well documented. OBJECTIVE:The aim of this study was to evaluate the effects of different methods of treatment on the healing process and the expression of growth factors (epidermal growth factor, basic fibroblast growth factor, transforming growth factor-beta(2) [TGF-beta(2)], platelet-derived growth factor-A, and platelet-derived growth factor-B) by histologic study, immunohistochemistry, and reverse transcription-polymerase chain reaction. METHODS:In this study, we produced wounds with a CO(2) laser on the backs of rats and used 4 different methods of wound treatment: occlusive dressing material, petrolatum ointment, beta-sitosterol ointment, and exposure to air (untreated) as a control. Five-millimeter biopsy specimens were obtained 1, 3, 5, 7, and 10 days after surgery for histologic evaluation and expression of growth factors from four different dressing sites. RESULTS:By microscopic examination, there was an acceleration of wound healing in the occlusive dressing wounds, as well as a lesser improvement in healing times with the petrolatum and beta-sitosterol-treated wounds, compared with the air-exposed control subjects. With immunohistochemistry, we observed that the tissue expression of TGF-beta(2) remained at a clearly lower level during the entire duration of wound healing in the occlusive dressing wound compared with the other treatment wounds. With reverse transcriptase-polymerase chain reaction, however, our data did not reveal statistically significant differences among the messenger RNA levels. CONCLUSIONS:Our results suggest that a decrease in the expression level of TGF-beta(2) under occlusive dressings could provide an environment in which the growth of human epidermal keratinocytes and re-epithelialization is promoted.
journal_name
Aesthet Surg Jjournal_title
Aesthetic surgery journalauthors
Jae Lee C,Hee Whang J,Lazova R,Ciesielski TE,Thomson JG,McCarthy T,Persing JAdoi
10.1016/j.asj.2006.12.002subject
Has Abstractpub_date
2007-01-01 00:00:00pages
55-64issue
1eissn
1090-820Xissn
1527-330Xpii
S1090-820X(06)00571-1journal_volume
27pub_type
杂志文章abstract::Recent technical advances in fat grafting and the development of surgical devices such as liposuction cannulae have made fat grafting a relatively safe and effective procedure. However, new guidelines issued by the American Society of Plastic Surgeons in 2009 announced that fat grafting to the breast is not a strongly...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章,评审
doi:10.1177/1090820X10373063
更新日期:2010-05-01 00:00:00
abstract::The author demonstrates his method of achieving optimal contour in the aging neck. Primary features of the technique are horizontal cuts in the vertical bands of the platysma muscle combined with a corset Z-plasty medial suture and bilateral rein plication suture. This combined procedure, which effectively lifts the s...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1016/j.asj.2007.12.006
更新日期:2008-03-01 00:00:00
abstract:BACKGROUND:The number of facelifts performed in the United States has steadily increased over the past decade. Moreover, the risk of venous thromboembolism in plastic surgery has been established in recent studies. OBJECTIVES:The authors investigate the overall complication rate in a single-center series to identify r...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1177/1090820X12442213
更新日期:2012-05-01 00:00:00
abstract:BACKGROUND:A significant proportion of patients seeking labiaplasty are nulliparous and may experience later changes to their labia following vaginal delivery. OBJECTIVES:In the present study, we report the long-term outcomes of a single surgeon's patient cohort who had vaginal delivery after labiaplasty. METHODS:A r...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjaa027
更新日期:2020-01-29 00:00:00
abstract:Background:While recent studies have reported modest to no difference in breast aesthetics for shaped and round implant types in breast augmentations, the anatomy and biomechanics in the setting of breast reconstruction is different. Objectives:Accordingly, we endeavored to evaluate whether two implant types impacted ...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjx210
更新日期:2018-05-15 00:00:00
abstract:BACKGROUND:Transgender patients may seek nonsurgical methods for facial masculinization and feminization as an adjunct or alternative to undergoing surgical procedures. OBJECTIVES:The authors reviewed the existing literature regarding this topic and provided an overview of nonsurgical techniques for facial masculiniza...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章,评审
doi:10.1093/asj/sjy253
更新日期:2019-04-08 00:00:00
abstract::The author provides his perspective on resurfacing procedures in dark-skinned patients, advising a cautious approach to laser resurfacing. Laser complications in Fitzpatrick skin types III to VI, including hyperpigmentation, hypopigmentation, and scarring, are well documented. Unlike chemical peeling and dermabrasion,...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1016/j.asj.2005.09.019
更新日期:2005-11-01 00:00:00
abstract::Surface aesthetics of the attractive nose are created by certain lines, shadows, and highlights, with specific proportions and breakpoints. Our evaluation of the nasal surface aesthetics is achieved using the concept of geometric polygons as aesthetic subunits, both to define the existing deformity and the aesthetic g...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1177/1090820X13478968
更新日期:2013-03-01 00:00:00
abstract::Full and high cheekbones are considered a desirable component of facial attractiveness. The aging process can result in a loss of facial volume and changes in facial contours. Cheek augmentation can replace lost facial volume, rejuvenate facial appearance, enhance cheek prominence, and improve facial symmetry. A new, ...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1016/j.asj.2009.03.004
更新日期:2009-05-01 00:00:00
abstract:BACKGROUND:A number of randomized controlled trials (RCTs) have investigated the role of perioperative corticosteroids in rhinoplasty. Each of these trials however has an insufficient sample sizes to reach definitive conclusions and detect harms. Three recent reviews have analyzed edema and ecchymosis outcomes followin...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章,meta分析,评审
doi:10.1093/asj/sjv138
更新日期:2016-02-01 00:00:00
abstract:Background:Muscle activity contributes to the enhancement of facial aging deformity, blepharospasm, cerebral palsy spasticity, trismus, torticollis, and other conditions. Myotomy of the involved muscles in order to reduce the deformity has variable success rates due to muscle healing and regeneration of activity. Obje...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjx207
更新日期:2018-04-06 00:00:00
abstract:BACKGROUND:Anatomical structures of the nose (including muscles) are elevated, sutured, or reshaped during rhinoplasty. Electromyography and electroneurography are the objective electrophysiologic tests performed for the direct measurement of nasal muscle function. OBJECTIVES:The authors investigate the predictive val...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1177/1090820X11398478
更新日期:2011-03-01 00:00:00
abstract::Effective hair removal is now available even for the darkest-skinned patients, including Fitzpatrick skin type VI. With the long-pulse YAG laser, a deeply penetrating wavelength enables energy to reach the hair bulbs, adequate power and pulse duration heat and destroy the hair follicle, and low melanin absorption ensu...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1067/maj.2003.23
更新日期:2003-03-01 00:00:00
abstract::The purpose of this article is to describe the necessary steps to correct both primary and postblepharoplasty lateral canthal and lower eyelid malpositions at the time of endoscopic face lifting. Endoscopic surgery is traditionally considered only for brow and forehead lifting. However, in our practice we have success...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjy244
更新日期:2019-04-08 00:00:00
abstract:BACKGROUND:Cryolipolysis has been shown to be a safe and effective noninvasive procedure for the reduction of localized subcutaneous fat. OBJECTIVES:The authors examine the safety, efficacy, and procedural growth of cryolipolysis (via the CoolSculpting device; Zeltiq, Pleasanton, California) in a single plastic surger...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1177/1090820X13494757
更新日期:2013-08-01 00:00:00
abstract::As injectable products have been introduced and as clinicians have gained experience with them, applications and techniques for injection have evolved, with better cosmetic results, enhanced patient safety, and greatly improved patient satisfaction. Within the past four years, several consensus recommendation panels h...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1177/1090820X10378697
更新日期:2010-07-01 00:00:00
abstract::"Second Thoughts" focuses on ways in which aesthetic plastic surgeons have modified or even dramatically changed their techniques over time to achieve optimal results. Contributors are Aesthetic Society members and other recognized experts. ...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1016/s1090-820x(98)80028-9
更新日期:1998-01-01 00:00:00
abstract:BACKGROUND:Bacterial biofilm on surfaces of mammary implants is a predisposing factor for several outcomes. Since Gram-positive bacteria are potential agents of biomaterial-associated infections (BAIs), their abilities to form biofilm on breast implants should be elucidated. OBJECTIVES:To evaluate biofilm formation on...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjaa416
更新日期:2020-12-30 00:00:00
abstract:BACKGROUND:Use of gluteal augmentation with fat increased by 3267% from 2002 to 2015, and the rate of death is highest compared with other aesthetic procedures: 1 in 3448 patients dies, compared with 1 in 55,000. OBJECTIVES:To retrospectively investigate patients who underwent this procedure at Oslo Plastic Surgery Cl...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章,评审
doi:10.1093/asj/sjy153
更新日期:2019-02-15 00:00:00
abstract::Paradigms in the treatment of aging have evolved to address volume loss as a central and primary hallmark of the aging face. The concept of "composite volumization" was recently proposed by Dr. Z. Paul Lorenc to describe the effect of Radiesse (Merz Aesthetics, Inc., Raleigh, NC), when placed on bone in the supraperio...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjy026
更新日期:2018-04-06 00:00:00
abstract:BACKGROUND:Although adipose-derived stem cells (ADSCs) and nanofat exert antiaging effects on skin, they contain cellular components that have certain limitations in clinical practice. Cell-free fat extract (Ceffe) is a fraction purified from nanofat through removal of cellular components and lipid remnants that contai...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjz306
更新日期:2020-07-13 00:00:00
abstract:BACKGROUND:Several growth factors and hyaluronic acid are implicated in fetal scarless healing. Whether these factors can be applied to an adult scar to improve scar characteristics is unknown. OBJECTIVES:This study compared the efficacy and safety of SKN2017B, a proprietary topical cream consisting of selective synth...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1093/asj/sjy185
更新日期:2019-02-15 00:00:00
abstract:BACKGROUND:Despite multiple advantages of fat grafting for calf augmentation and re-shaping over traditional silicone calf implants, few reports have been published. OBJECTIVES:To report our technique and results with autologous fat grafting for calf augmentation and reshaping. METHODS:A retrospective review of the s...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjv166
更新日期:2016-02-01 00:00:00
abstract:BACKGROUND:A critical issue for aesthetic surgeons may be whether some patients have psychiatric conditions that contraindicate cosmetic procedures. OBJECTIVE:This study reports on the results of an e-mail survey of American Society for Aesthetic Plastic Surgery (ASAPS) members about their awareness of and experiences...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1067/maj.2002.129451
更新日期:2002-11-01 00:00:00
abstract:BACKGROUND:Breast augmentation through incisions in the axillae is an option for patients who wish to avoid scars on the breasts. The axillary approach also preserves the mammary parenchyma and lactiferous ducts. The utility of video-assisted endoscopy during this procedure as a means to improve safety and aesthetic ou...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章,随机对照试验
doi:10.1093/asj/sju076
更新日期:2015-03-01 00:00:00
abstract:BACKGROUND:Given the wide application of autologous fat grafting, a new emphasis on fat processing techniques has emerged in an effort to limit unpredictable degrees of resorption often seen with this procedure. With the growing interest in regenerative medicine, approaches to supplement fat grafts with adipose-derived...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1177/1090820X13487371
更新日期:2013-07-01 00:00:00
abstract:BACKGROUND:The ears increase in all dimensions over the years (eg, length, helix diameter, lobe length), but the most obvious change is the elongation or ptosis of the lobe. Its correction should be considered a part of facial rejuvenation. OBJECTIVES:The authors presented the surgical procedure they have been utilizi...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjz348
更新日期:2020-07-13 00:00:00
abstract::Increasingly, patients are seeking minimally invasive methods to tighten skin and remodel adipose tissue. A large treatment gap exists among 3 types of patients: (1) the younger demographic, who increasingly desire soft tissue tightening without traditional operations, scars, and downtime; (2) patients with soft tissu...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjz055
更新日期:2019-04-08 00:00:00
abstract:Background:Although many patients who undergo reduction mammaplasty are obese, reports on whether obesity is a risk factor for postoperative complications have been conflicting. Objectives:This systematic literature review and meta-analysis aimed to evaluate the relationship between obesity and surgical complications ...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章,meta分析,评审
doi:10.1093/asj/sjw189
更新日期:2017-03-01 00:00:00
abstract::As the popularity of female cosmetic genital surgery has grown, so has the number of publications detailing surgical techniques, particularly regarding labiaplasty. As a nascent surgical field, much room remains for finesse and exploration of new techniques to optimize outcomes and patient satisfaction. We present the...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjz287
更新日期:2020-09-14 00:00:00