Abstract:
BACKGROUND:Although adipose-derived stem cells (ADSCs) and nanofat exert antiaging effects on skin, they contain cellular components that have certain limitations in clinical practice. Cell-free fat extract (Ceffe) is a fraction purified from nanofat through removal of cellular components and lipid remnants that contains various growth factors. OBJECTIVES:The purpose of this study was to evaluate the effects of Ceffe on cultured human dermal fibroblasts in vitro and on the dermis of nude mice in vivo. METHODS:In the in vitro study, human dermal fibroblasts were cultured with Ceffe for 72 hours, followed by flow cytometry measurement of cell proliferation and cell cycle. In the in vivo study, different concentrations of Ceffe were injected into the dorsal skin of nude mice for 4 weeks. The thickness of the dermis; proliferation of cells; density of the capillary; and expressions of type I and III collagen (Col-1 and Col-3), matrix metalloproteinase-1, matrix metalloproteinase-3, tissue inhibitor of metalloproteinase-1, and tissue inhibitor of metalloproteinase-3 were measured through histologic and Western blot analyses. RESULTS:Ceffe significantly increased cell proliferation in cultured dermal fibroblasts. In the mouse skin, Ceffe significantly increased the thickness of the dermis, number of proliferating cells, density of the capillary, and expressions of Col-1 and Col-3. CONCLUSIONS:Ceffe increased the dermal thickness of nude mice, possibly by enhancing angiogenesis and extracellular matrix production, and can therefore be used for skin rejuvenation.
journal_name
Aesthet Surg Jjournal_title
Aesthetic surgery journalauthors
Xu Y,Deng M,Cai Y,Zheng H,Wang X,Yu Z,Zhang W,Li Wdoi
10.1093/asj/sjz306subject
Has Abstractpub_date
2020-07-13 00:00:00pages
904-913issue
8eissn
1090-820Xissn
1527-330Xpii
5611304journal_volume
40pub_type
杂志文章abstract::Arm contour improvement is a desired goal of the massive weight loss and the aging population who want to maintain the arm aesthetics. Brachioplasty is a growing and safe procedure to improve the arm contour and different approaches and innovative treatment options have been described since the 1930s. This paper revie...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章,评审
doi:10.1093/asj/sjx218
更新日期:2018-07-13 00:00:00
abstract:BACKGROUND:Although there is an abundance of data in the literature regarding the safety of breast reduction and augmentation, nearly all of the literature concerning mastopexy describes techniques. There are few studies regarding revision and complication rates for mastopexy procedures. METHODS:A retrospective review...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1016/j.asj.2006.12.014
更新日期:2007-03-01 00:00:00
abstract::Perioperative hyperglycemia is a well-known risk factor for surgical morbidity such as wound healing, infection, and prolonged hospitalization. This association has been reported for a number of surgical subspecialties, including plastic surgery. Specialty-specific guidelines have become increasingly available in the ...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章,评审
doi:10.1093/asj/sjw064
更新日期:2016-07-01 00:00:00
abstract:BACKGROUND:The demand for minimally invasive cosmetic procedures has continued to rise, yet few studies have examined this patient population. OBJECTIVES:This study sought to define the demographics, social characteristics, and motivations of patients seeking minimally invasive facial cosmetic procedures. METHODS:A p...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjv094
更新日期:2015-11-01 00:00:00
abstract:Background:Although many patients who undergo reduction mammaplasty are obese, reports on whether obesity is a risk factor for postoperative complications have been conflicting. Objectives:This systematic literature review and meta-analysis aimed to evaluate the relationship between obesity and surgical complications ...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章,meta分析,评审
doi:10.1093/asj/sjw189
更新日期:2017-03-01 00:00:00
abstract:BACKGROUND:Tranexamic acid (TXA) is an antifibrinolytic agent shown to decrease intraoperative bleeding, reduce transfusions, and improve outcomes across multiple specialties. Within plastic surgery, initial reports are encouraging but formal studies are lacking. OBJECTIVES:The aim of this study was to determine wheth...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjaa072
更新日期:2021-01-25 00:00:00
abstract:BACKGROUND:Concerns about the safety of silicone breast implants have existed for years, but a causal relationship between systemic complaints and SBI has not been proven. Nevertheless, women are worried and even request explantation. OBJECTIVES:This study aimed to review the explantation procedures performed, focusin...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjaa337
更新日期:2020-11-30 00:00:00
abstract:BACKGROUND:Excessive concavity of the lower lateral crura can cause significant aesthetic problems for the nasal tip and can be associated with significant functional problems, such as insufficiencies in the external nasal valve. OBJECTIVES:The aim of this study was to develop a novel technique for the improvement of ...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjaa018
更新日期:2020-09-14 00:00:00
abstract::"Second Thoughts" focuses on ways in which aesthetic plastic surgeons have modified or even dramatically changed their techniques over time to achieve optimal results. Contributors are Aesthetic Society members and other recognized experts. ...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1016/s1090-820x(98)80028-9
更新日期:1998-01-01 00:00:00
abstract::Implant texture is an important factor influencing implant selection for breast augmentation. Natrelle Biocell implants are characterized by macrotextured shell surfaces containing irregularly arranged concavities with large open-pore diameters and depths. These properties facilitate adhesion of the implant to the sur...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1177/1090820X14538635
更新日期:2014-08-01 00:00:00
abstract:BACKGROUND:The clinical results of many studies on platelet-rich plasma (PRP) differ because there is a lack of standardization in PRP preparation and administration, as well as many variables such as PRP preparation methods, platelet concentration, and platelet activation. OBJECTIVES:The aim of this study was to inve...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjab043
更新日期:2021-01-25 00:00:00
abstract:BACKGROUND:Breast reduction is a commonly performed procedure. Understanding the postoperative complication profile is important for preoperative planning and patient education. OBJECTIVES:The authors sought to assess complication rates following breast reduction in females and identify potential risk factors. METHOD...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjaa146
更新日期:2020-11-19 00:00:00
abstract:BACKGROUND:Free tissue transfer with lower abdominal flaps for autologous breast reconstruction is not suitable for all patients. The latissimus dorsi (LD) musculocutaneous flap is an alternative, effective method for both immediate and delayed breast reconstruction. OBJECTIVES:The authors assess their experience with...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1177/1090820X12437783
更新日期:2012-03-01 00:00:00
abstract::The superior pedicle reduction mammaplasty allows most premenopausal women to maintain lactational capabilities and nipple sensation. It is a relatively simple breast reduction technique which, according to the author, achieves an aesthetically pleasing breast shape with no "bottoming out" and a high level of patient ...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1016/j.asj.2005.05.010
更新日期:2005-07-01 00:00:00
abstract:Background:While recent studies have reported modest to no difference in breast aesthetics for shaped and round implant types in breast augmentations, the anatomy and biomechanics in the setting of breast reconstruction is different. Objectives:Accordingly, we endeavored to evaluate whether two implant types impacted ...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjx210
更新日期:2018-05-15 00:00:00
abstract::As the popularity of female cosmetic genital surgery has grown, so has the number of publications detailing surgical techniques, particularly regarding labiaplasty. As a nascent surgical field, much room remains for finesse and exploration of new techniques to optimize outcomes and patient satisfaction. We present the...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjz287
更新日期:2020-09-14 00:00:00
abstract:BACKGROUND:Anatomical structures of the nose (including muscles) are elevated, sutured, or reshaped during rhinoplasty. Electromyography and electroneurography are the objective electrophysiologic tests performed for the direct measurement of nasal muscle function. OBJECTIVES:The authors investigate the predictive val...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1177/1090820X11398478
更新日期:2011-03-01 00:00:00
abstract::As injectable products have been introduced and as clinicians have gained experience with them, applications and techniques for injection have evolved, with better cosmetic results, enhanced patient safety, and greatly improved patient satisfaction. Within the past four years, several consensus recommendation panels h...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1177/1090820X10378697
更新日期:2010-07-01 00:00:00
abstract::The hairline and frontal hair volume are frequently overlooked aspects of attractive facial proportion and overall facial aesthetics. The author contends that patient benefit from hair restoration surgery is significant, and these procedures should be routinely considered as part of a complete facial rejuvenation. ...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1016/j.asj.2004.08.007
更新日期:2004-11-01 00:00:00
abstract:BACKGROUND:Although placement of silicone implants remains the standard technique for gluteal augmentation, lipoinjection of autologous fat obtained from lipoplasty is emerging as an alternative procedure. OBJECTIVE:We report the results of large-volume lipoinjection of the gluteal region in a series of 96 patients. ...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1067/maj.2002.121960
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND:A critical issue for aesthetic surgeons may be whether some patients have psychiatric conditions that contraindicate cosmetic procedures. OBJECTIVE:This study reports on the results of an e-mail survey of American Society for Aesthetic Plastic Surgery (ASAPS) members about their awareness of and experiences...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1067/maj.2002.129451
更新日期:2002-11-01 00:00:00
abstract:BACKGROUND:Cryolipolysis has been shown to be a safe and effective noninvasive procedure for the reduction of localized subcutaneous fat. OBJECTIVES:The authors examine the safety, efficacy, and procedural growth of cryolipolysis (via the CoolSculpting device; Zeltiq, Pleasanton, California) in a single plastic surger...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1177/1090820X13494757
更新日期:2013-08-01 00:00:00
abstract::Numerous surgical options for breast reduction have been described, but in the current healthcare environment, efficiency is of the utmost importance. In this Featured Operative Technique, the authors describe an efficient, reproducible, and simple method for minimal to moderate reduction mammaplasty that utilizes a s...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sju011
更新日期:2015-01-01 00:00:00
abstract::The male breast area can be difficult to treat following massive weight loss. In such patients, it is essential to correct the deformity without leaving disfiguring scars over the anterior surface of the chest, if possible. We suggest a surgical technique that involves a torsoplasty with concomitant nipple-areolar com...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1016/j.asj.2008.07.008
更新日期:2008-11-01 00:00:00
abstract:Background:Lower eyelid blepharoplasty has continued to evolve with ongoing debate regarding optimal techniques. Despite large case series publishing excellent results and minimal complications, the true longevity of these procedures remains unclear. Objectives:The aim of this study was to determine how thoroughly the...
journal_title:Aesthetic surgery journal
pub_type: 历史文章,杂志文章,评审
doi:10.1093/asj/sjy186
更新日期:2018-11-12 00:00:00
abstract:BACKGROUND:It is well established that abdominoplasty confers a uniquely high risk of venous thromboembolism (VTE) complications. However, chemoprophylaxis is not routinely utilized due to the risk of bleeding complications. Fondaparinux, a factor Xa inhibitor FDA approved in 2001 for postoperative VTE prophylaxis, has...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjz184
更新日期:2019-10-15 00:00:00
abstract::Increasingly, patients are seeking minimally invasive methods to tighten skin and remodel adipose tissue. A large treatment gap exists among 3 types of patients: (1) the younger demographic, who increasingly desire soft tissue tightening without traditional operations, scars, and downtime; (2) patients with soft tissu...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjz055
更新日期:2019-04-08 00:00:00
abstract:BACKGROUND:Despite the rapid increase in the number of publications pertaining to COVID-19, there is a lack of data examining patient outcomes following elective procedures performed during this pandemic. OBJECTIVES:The purpose of this investigation was to examine the postoperative outcomes of patients who underwent e...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjaa180
更新日期:2021-01-25 00:00:00
abstract:BACKGROUND:Capsular contracture (CC) is the most common complication following primary breast augmentation and one of the most common causes of reoperation. Various studies have suggested certain risk factors, including incision choice. OBJECTIVES:The authors investigate a possible association between the three most c...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1177/1090820X12444267
更新日期:2012-05-01 00:00:00
abstract:BACKGROUND:Women tend to develop more and deeper wrinkles in the perioral region than men. Although much is known about the complex mechanisms involved in skin aging, previous studies have described histologic differences between men and women with respect to skin aging only incidentally and have not investigated the p...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1016/j.asj.2009.08.018
更新日期:2009-11-01 00:00:00