Lymphoproliferative disorders after immunosuppressive therapy for aplastic anemia: a case report and literature review.

abstract：:Natural killer (NK) cell activity against K562 cell targets and the distribution of T cell subpopulations were investigated in the peripheral blood of 25 patients affected by beta thalassemia major, 18 clinically healthy heterozygotes, and 25 age-matched normal subjects. It was found that thalassemia major patients di...

journal_title：Acta haematologica

authors： Neri A,Brugiatelli M,Iacopino P,Callea V,Ronco F

更新日期：1984-01-01 00:00:00

abstract：:Among the 193 patients (82 female, 111 male) treated primarily for Hodgkin's disease at our clinic between 1990 and 2001 and followed up until 2003, 42 (22%) had mediastinal bulky tumours (MBTs) by the Cotswolds criteria. The rate of MBT diagnosis was significantly greater in the early stage of the disease, these pati...

journal_title：Acta haematologica

authors： Keresztes K,Lengyel Z,Devenyi K,Vadasz G,Miltenyi Z,Illes A

更新日期：2004-01-01 00:00:00

abstract：:Neoplastic cells of 18 patients with multiple myeloma were studied using a panel of 6 monoclonal antibodies to B cells and monospecific antisera against the light chain types of immunoglobulin. OKT10 bound to the myeloma cells of all the patients, although only a small percentage of the cells reacted in 3 instances. M...

journal_title：Acta haematologica

authors： Katagiri S,Yonezawa T,Tamaki T,Kanayama Y,Kuyama J,Ohnishi M,Tsubakio T,Kurata Y,Tarui S

更新日期：1984-01-01 00:00:00

abstract：:Of 34 patients with chronic inflammatory bowel disease (CIBD), 4 developed well-documented episodes of deep-venous thrombosis. All 4 patients had active disease at the time of thrombosis. This group was studied to determine if the tendency to deep-venous thrombosis in patients with CIBD was associated with reduced ant...

journal_title：Acta haematologica

authors： Ghosh S,Mackie MJ,McVerry BA,Galloway M,Ellis A,McKay J

更新日期：1983-01-01 00:00:00

abstract：:A 77-year-old woman presented to the outpatient hematology clinic in August 2001 with leukocytosis, recurrent bacterial infections, sweating and weight loss. Bone marrow biopsy showed 80% infiltration with lymphoid cells having a prolymphocytic morphology. Flow-cytometric immunophenotype analysis showed that over 80% ...

journal_title：Acta haematologica

authors： Zver S,Kokalj Vokac N,Zagradisnik B,Erjavec A,Zagorac A,Zupan IP,Cernelc P

更新日期：2004-01-01 00:00:00

abstract：:95 of 1,019 (9.3%) sera with monoclonal immunoglobulins (MIg) were found to have cold-reacting lymphocytotoxins (LCT). There was no difference in the prevalence of LCT in multiple myeloma, macroglobulinemia, cancer, lymphoma or benign monoclonal gammopathy. Prevalence of LCT was similar in various classes and types of...

journal_title：Acta haematologica

authors： Pruzanski W,Capes H,Ramirez G,Falk J

更新日期：1985-01-01 00:00:00

abstract：:Allogeneic stem cell transplantation (SCT) is the treatment of choice for selected patients with chronic myeloid leukemia (CML). However, it is associated with a high risk of treatment-related mortality (TRM) and morbidity. To assist in decision making about transplantation, a simple scoring system to assess the risk ...

journal_title：Acta haematologica

authors： Qazilbash MH,Devetten MP,Abraham J,Lynch JP,Beall CL,Weisenborn R,Bunner P,Ericson SG

更新日期：2003-01-01 00:00:00

abstract：:Marginal-zone B cells of the mucosa-associated lymphoid tissue (MALT) are the normal counterpart of the neoplastic cells in MALT lymphoma. In both cases these lymphocytes express surface immunoglobulins, but are negative when stained for B cell associated antigens like CD10 and CD23. Furthermore, the B cell gene rearr...

journal_title：Acta haematologica

authors： Fritscher-Ravens A,Petrasch S,Tiemann M,Wacker H,Dörr T,Kemmeries G,Hilgers W,Reinacher-Schick A,Kunstmann E,Schmiegel W

更新日期：1999-01-01 00:00:00

abstract：:A 44-year-old Japanese male having refractory anemia with excess of blasts (RAEB) preceding acute myelomonocytic leukemia (AMMoL) with dysplastic marrow eosinophilia (M4Eo in the FAB classification) is reported. Sequential cytogenetic studies revealed a specific chromosomal abnormality, inv(16) (p13q22), when RAEB was...

journal_title：Acta haematologica

authors： Horiike S,Misawa S,Nishida K,Nishigaki H,Tsuda S,Taniwaki M,Takino T,Abe T

更新日期：1989-01-01 00:00:00

abstract：:The distribution of thymus-dependent (T cells) and bone marrow-derived lymphocytes (B cells) was studied in 74 patients with Hodgkin's disease and 33 normal controls. A T cell deficit was found in untreated patients as well as in long-term survivors in remission. Therapy slightly enhanced the T cell depletion in Hodgk...

journal_title：Acta haematologica

authors： Many A,Biniaminov M,Rosenthal E,Aghai E,Ramot B

更新日期：1976-01-01 00:00:00

abstract：:The frequency of chronic lymphocytic leukemia (CLL) varies a great deal from one population to another. We have undertaken to compare the aspects of CLL in Maghreb and Europe through two series of comparable importance, studied during the same period and under similar conditions in Algiers and Amiens. This comparison ...

journal_title：Acta haematologica

authors： Bellabes S,Hamman P,Desablens B,Colonna P,Messerschmitt J

更新日期：1983-01-01 00:00:00

abstract：:Micromegakaryocytes (MMK) were defined morphologically by the cell area, nucleus form and cytoplasmic structure. Bone marrow smears of 7,156 patients were retrospectively analyzed. MMK were found most frequently and abundantly in acute non-lymphatic leukaemia, chronic myeloid leukaemia and pre-leukaemia. The presence ...

journal_title：Acta haematologica

authors： Wiesneth M,Pflieger H,Kubanek B,Heimpel H

更新日期：1980-01-01 00:00:00

abstract：:10 patients with paroxysmal nocturnal hemoglobinuria were studied taking 109 normal subjects of the Cuban population as control group. 26 HLA antigens corresponding to loci A and B were studied in both groups. Phenotypical frequency of both groups were compared. No statistically significant increase was found for any ...

journal_title：Acta haematologica

authors： Ustariz CR,Arce S,Hernández P,Almaguer M,Pérez S,Ballester JM

更新日期：1980-01-01 00:00:00

abstract：BACKGROUND/AIMS:The aim of this work was to investigate the efficacy and predictive factors of CLAG treatment in refractory or relapsed (R/R) acute myeloid leukemia (AML) patients. METHODS:Sixty-seven R/R AML patients were enrolled in this prospective cohort study and treated by a CLAG regimen: 5 mg/m2/day cladribine ...

journal_title：Acta haematologica

authors： Wang L,Xu J,Tian X,Lv T,Yuan G

更新日期：2019-01-01 00:00:00

abstract：:To test whether anti-idiotypic immunoregulation of factor VIII(FVIII)-inhibiting antibodies could be feasible in hemophiliacs, we assayed the minimal number and range of immunogenic, functional FVIII epitopes to which a series of murine anti-FVIII monoclonal antibodies (MAb) were directed. Rabbit anti-idiotypic sera t...

journal_title：Acta haematologica

authors： Tiarks CY,Humphreys RE,Pechet L

更新日期：1990-01-01 00:00:00

abstract：:A case of acquired haemophilia A presenting with extensive spontaneous bruising and anaemia is reported. The anaemia was due to myelodysplastic syndrome (FAB: refractory anaemia with ringed sideroblasts). A factor-VII:C-specific inhibitor was also found. Prednisone and pyridoxine were given, and the inhibitor became u...

journal_title：Acta haematologica

authors： Lin CK,Liang R,Liu HW,Tse PW,Chan GT

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Posterior reversible encephalopathy syndrome (PRES) is a rare but serious complication after allogeneic hematopoietic stem cell transplantation (alloHSCT). Among others, calcineurin inhibitors (CNI) for prophylaxis of graft-versus-host disease (GvHD) may promote the development of PRES, but the pathomechanis...

journal_title：Acta haematologica

authors： Schmidt V,Prell T,Treschl A,Klink A,Hochhaus A,Sayer HG

更新日期：2016-01-01 00:00:00

abstract：:A modified cytochemical method was developed for demonstrating magnesium-activated adenosine triphosphatase in haemic cells. The enzyme was shown in a variety of normal and leukaemic, unfixed cells. The high sensitivity of this enzyme to all fixatives tried in this study hampered further exploration and characterizati...

journal_title：Acta haematologica

authors： Khalaf MR,Hayhoe FG

更新日期：1987-01-01 00:00:00

abstract：:Two pregnancies at risk for Fanconi's anemia have been monitored by a cytogenetic method in the first trimester of gestation. The rate of chromosome breakage was evaluated in spontaneous mitoses from a direct preparation of trophoblasts in one case and from mitoses obtained from standard cultures and from mitoses trea...

journal_title：Acta haematologica

authors： Dallapiccola B,Doria Lamba Carbone L,Ferranti G,Cristiani ML,Dagna Bricarelli F

更新日期：1985-01-01 00:00:00

abstract：:Richter syndrome (RS) describes the development of high-grade non-Hodgkin's lymphoma (NHL) from low-grade NHL. RS isolated to the brain is very rare and has a poor prognosis. We describe the cases of high-grade large B-cell diffuse NHL in a 56-year-old male with chronic lymphocytic leukemia and in a 71-year-old female...

journal_title：Acta haematologica

authors： Stuplich M,Mayer K,Kim Y,Thanendrarajan S,Simon M,Schäfer N,Glas M,Schmidt-Wolf IG,Herrlinger U

更新日期：2012-01-01 00:00:00

abstract：:A case of steroid-resistant acquired pure red-cell aplasia associated with a relative and absolute increase of TG cells is described. Removal of T cells enhanced erythroid colony and burst formation in vitro, and it is suggested that TG cells may be implicated in the pathogenesis of this case of acquired pure red-cell...

journal_title：Acta haematologica

authors： Linch DC,Cawley JC,MacDonald SM,Masters G,Roberts BE,Antonis AH,Waters AK,Sieff C,Lydyard PM

更新日期：1981-01-01 00:00:00

abstract：:Drug-induced immune hemolytic anemia is a rare but underdiagnosed and potentially fatal condition. We report a case of severe hemolytic anemia induced by cefoxitin in a 45-year-old woman admitted with menometrorrhagia. Hemoglobin levels reached a nadir of 4.7 g/dl approximately 72 h after cefoxitin initiation, and hem...

journal_title：Acta haematologica

authors： Leaf DE,Langer NB,Markowski M,Garratty G,Diuguid DL

更新日期：2010-01-01 00:00:00

abstract：:In 83 children with acute lymphoblastic leukaemia (ALL) the immunological phenotype of the lymphoblasts was determined using E rosetting, monoclonal anti-T cell sera, surface immunoglobulin staining and common ALL antiserum. The data were compared with acid alpha-naphthyl acetate esterase (ANAE) and acid phosphatase (...

journal_title：Acta haematologica

authors： Veerman AJ,Huismans DR,van Zantwijk CH

更新日期：1983-01-01 00:00:00

abstract：:A case of acute leukaemia with t(4;11) chromosomal abnormality in a 28-year-old woman is reported. At diagnosis, two blast cell populations were seen: 60% of the cells were small cells with lymphoid morphology, 40% were large cells with monocytic morphology. Cytochemical examination was consistent with acute myeloid l...

journal_title：Acta haematologica

authors： Campos L,Espinouse D,Felman P,Charrin C,Gentilhomme O,Germain D

更新日期：1986-01-01 00:00:00

abstract：:A 69-year-old woman with typical thrombotic thrombocytopenic purpura is reported, who was treated successfully by plasma exchange. An initial chromosomal analysis of peripheral blood lymphocytes revealed abnormal patterns of 45, XO/46, XX/47, XXX; a second analysis showed 45, XO/46, XX/47, XXX/47, XX + 21, and a third...

journal_title：Acta haematologica

authors： Itoh Y,Taniguchi T,Takeyama N,Kuriki H,Tanaka T

更新日期：1990-01-01 00:00:00

abstract：:Recently, the use of novel targeted drugs has changed the treatment paradigms in chronic lymphocytic leukemia (CLL). Among the several drugs used for the management of relapsed/refractory (R/R) CLL, Bruton tyrosine kinase inhibitors (ibrutinib and acalabrutinib), phosphatidylinositol 3-kinase inhibitors (idelalisib an...

journal_title：Acta haematologica

authors： Smolewski P,Robak T

更新日期：2020-11-25 00:00:00

abstract：:Fibroblast-like cells were grown from the bone marrow of acute lymphoblastic leukemia (ALL) patients before, during and off therapy. A diminished growth capacity was observed in cells from patients before and during therapy. In the three groups studied, differences were also observed in the effect of hydrocortisone on...

journal_title：Acta haematologica

authors： Bruzzone MS,Minguell JJ

更新日期：1985-01-01 00:00:00

abstract：:Non-Hodgkin's lymphomas are among the most challenging diseases to treat and their course ranges from very aggressive and rapidly fatal tumors to some of the most indolent, well-tolerated malignancies in man. ...

journal_title：Acta haematologica

authors： Bonadonna G,Bajetta E

更新日期：1987-01-01 00:00:00

abstract：:There have been many reports of patients with ampulla cardiomyopathy described as takotsubo-shaped cardiomyopathy in the cardiovascular field. This unique cardiomyopathy is characterized by transient apical ballooning and hypokinesis of the left ventricle. We describe 2 cases of ampulla cardiomyopathy associated with ...

journal_title：Acta haematologica

authors： Takeoka Y,Nakamae M,Nakamae H,Hagihara K,Sakamoto E,Nakane T,Koh H,Koh KR,Ohta K,Yamane T,Hino M

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Umbilical cord blood (UCB) contains haematopoietic stem cells and can be used as an alternative to bone marrow transplantation in certain cases. Engraftment was dependent upon the haematopoietic progenitor cell content of the cord blood units. This study was designed to investigate the influen...

journal_title：Acta haematologica

authors： Solves P,Perales A,Moraga R,Saucedo E,Soler MA,Monleon J

更新日期：2005-01-01 00:00:00