Monitoring of pregnancies at risk for Fanconi's anemia by chorionic villi sampling.

abstract：:In 33 children with cyanotic congenital heart disease the platelet function has been studied. The most significant changes were reduced platelet adhesiveness to glass and impaired availability of platelet factor 3 in nearly 50% of the patients. Although clot retraction was poor in 84% of them, thrombocytopenia and pro...

journal_title：Acta haematologica

authors： Bhargava M,Sanyal SK,Thapar MK,Kumar S,Hooja V

更新日期：1976-01-01 00:00:00

abstract：:A 3-year-old child developed severe aplastic anaemia following hepatitis A. Since no HLA-compatible donor was available, he was treated with oxymetholone, antithymocytic globulin and methylprednisolone, but no haematologic recovery was observed and he consequently died of pneumonia. Although the association of aplasti...

journal_title：Acta haematologica

authors： Doménech P,Palomeque A,Martínez-Gutiérrez A,Viñolas N,Vela E,Jiménez R

更新日期：1986-01-01 00:00:00

abstract：:There have been many reports of patients with ampulla cardiomyopathy described as takotsubo-shaped cardiomyopathy in the cardiovascular field. This unique cardiomyopathy is characterized by transient apical ballooning and hypokinesis of the left ventricle. We describe 2 cases of ampulla cardiomyopathy associated with ...

journal_title：Acta haematologica

authors： Takeoka Y,Nakamae M,Nakamae H,Hagihara K,Sakamoto E,Nakane T,Koh H,Koh KR,Ohta K,Yamane T,Hino M

更新日期：2007-01-01 00:00:00

abstract：:Acute myelogenous leukemia (AML) of the inbred Wistar/Furth (W/Fu) rat is pathophysiologically similar to human AML. Subcutaneous transplantation of 1.0 X 10(6) cells of a clonal tissue culture line of W/Fu AML into 6- to 8-week-old rats produced local myeloblastomas in 8--10 days which progressed to infiltration of r...

journal_title：Acta haematologica

authors： Greenberger JS,Bocaccino CA,Szot SJ,Moloney WC

更新日期：1977-03-01 00:00:00

abstract：:Macrothrombocytopenia (MTP) is a group of rare disorders characterized by giant platelets, thrombocytopenia, and variable association with abnormal bleeding. Inherited MTP are frequently misdiagnosed as immune thrombocytopenia. Associated second-organ manifestation can help narrow down syndromic MTPs. We describe a ca...

journal_title：Acta haematologica

authors： Karki NR,Ajebo G,Savage N,Kutlar A

更新日期：2021-01-01 00:00:00

abstract：OBJECTIVE:To investigate a family with factor VII (FVII) deficiency from Argentina. PATIENTS AND METHODS:The proposita is a 14-year-old girl who presented with a mild to moderate bleeding tendency. Menorrhagia is controlled with periodical administration of small doses of recombinant FVII concentrate. The mother of th...

journal_title：Acta haematologica

authors： Girolami A,Paoletti M,Ferrari S,Garcia D

更新日期：2021-01-01 00:00:00

abstract：:We describe an unusual case of invasive pulmonary aspergillosis (IPA) complicated by subclavian artery occlusion in a 32-year-old man with severe aplastic anemia, who underwent allogeneic stem cell transplantation. He was severely neutropenic after the conditioning for transplantation, but he had no history of fungal ...

journal_title：Acta haematologica

authors： Hashino S,Imamura M,Tanaka J,Mori A,Noto S,Kobayashi S,Kasai M,Asaka M

更新日期：1997-01-01 00:00:00

abstract：:Recently, a factor was discovered in the serum of hepatectomized animals which was capable of augmenting the hepatic erythropoietin response to hypoxia when injected into normal rats. This substance was localized in the liver via an in situ perfusion technique and was termed the hepatic erythropoietic factor (HEF). Pa...

journal_title：Acta haematologica

authors： Naughton BA,Liu P,Naughton GK,Gordon AS

更新日期：1983-01-01 00:00:00

abstract：:Acute megakaryoblastic leukemia is uncommon and comprises about 5% of acute nonlymphoid leukemias in the French-American-British classification. Cell lines from such leukemias are relatively rare with only about 8 reported in the literature. We established a cell line from a case of acute megakaryoblastic leukemia ari...

journal_title：Acta haematologica

authors： Skinnider LF,Pabello P,Zheng CY

更新日期：1997-01-01 00:00:00

abstract：:Marginal-zone B cells of the mucosa-associated lymphoid tissue (MALT) are the normal counterpart of the neoplastic cells in MALT lymphoma. In both cases these lymphocytes express surface immunoglobulins, but are negative when stained for B cell associated antigens like CD10 and CD23. Furthermore, the B cell gene rearr...

journal_title：Acta haematologica

authors： Fritscher-Ravens A,Petrasch S,Tiemann M,Wacker H,Dörr T,Kemmeries G,Hilgers W,Reinacher-Schick A,Kunstmann E,Schmiegel W

更新日期：1999-01-01 00:00:00

abstract：:We have demonstrated that hemopoietic organ fibroblastoid cells can produce colony-stimulating activity (CSA) in vitro. Skin fibroblasts also produced CSA. The colonies which formed were restricted to the granulocyte/macrophage differentiation pathways. A linear relationship was obtained for granulocyte/macrophage col...

journal_title：Acta haematologica

authors： Brockbank KG,van Peer CM

更新日期：1983-01-01 00:00:00

abstract：:Non-Hodgkin's lymphomas are among the most challenging diseases to treat and their course ranges from very aggressive and rapidly fatal tumors to some of the most indolent, well-tolerated malignancies in man. ...

journal_title：Acta haematologica

authors： Bonadonna G,Bajetta E

更新日期：1987-01-01 00:00:00

abstract：:All-trans-retinoic acid (ATRA) combined with anthracyclines is currently the standard treatment for acute promyelocytic leukemia (APL). In elderly patients the presence of comorbidities, such as cardiomyopathy or different organ failures, often represents an absolute contraindication to standard chemotherapy. In this ...

journal_title：Acta haematologica

authors： Finizio O,Pezzullo L,Rocco S,Bene L,De Rosa C,Nunziata GR,Mettivier V

更新日期：2007-01-01 00:00:00

abstract：:A 38-year-old Japanese man had suffered from trichophyton infection for several years. The white blood cell count was 20,300/mm3, including 54% abnormal lymphocytes with irregularly convoluted nuclei. Adult T-cell leukemia (ATL) was diagnosed based on proliferation of CD4-positive lymphocytes, positive anti-HTLV-I ant...

journal_title：Acta haematologica

authors： Okamura T,Shibuya T,Harada M,Niho Y

更新日期：1992-01-01 00:00:00

abstract：:Eleven patients with acute myeloid leukaemia (AML) in first complete remission (CR) were treated with alfa-2a-interferon (for short 'interferon') maintenance therapy, at a dose of 3 MU twice to thrice weekly subcutaneously. Adjustments were made to maintain neutrophil counts > 1 x 10(9)/l and platelet counts > 100 x 1...

journal_title：Acta haematologica

authors： McSweeney EN,Worman CP,Tsakona CP,Jewel AP,Hoffbrand AV,Milligan DW,Burnett AK,Lewis ML,Goldstone AH

更新日期：1993-01-01 00:00:00

abstract：:A case of systemic mastocytosis with unusual clinical manifestations, appearing as an isolated splenohepatomegaly, is described. The proliferative character is evident from the cytological characteristics of immaturity and the presence of a moderate percentage of mast cells in the peripheral blood. These cells make up...

journal_title：Acta haematologica

authors： Woessner S,Lafuente R,Pardo P,Rosell R,Rozman C,Sans-Sabrafen J

更新日期：1977-01-01 00:00:00

abstract：BACKGROUND/AIMS:The study was undertaken to understand the characteristic of plasma cell leukemia (PCL) in China. METHODS:We reviewed and compared medical data of 22 primary PCL, 9 secondary PCL and 461 multiple myeloma (MM) diagnosed at our institute from January 2000 to January 2008. RESULTS:The median onset ages o...

journal_title：Acta haematologica

authors： Peijing Q,Yan X,Yafei W,Dehui Z,Zengjun L,Junyuan Q,Yaozhong Z,Lugui Q

更新日期：2009-01-01 00:00:00

abstract：:In cutaneous T-cell lymphomas (CTCL; mycosis fungoides and Sézary syndrome), the standard therapies tend to be effective but not curative. Single drug therapy with either interferon-alpha or retinoids shows a response rate of about 45%. In this article, we report the results obtained in the treatment of CTCL with a co...

journal_title：Acta haematologica

authors： Dreno B,Celerier P,Litoux P

更新日期：1993-01-01 00:00:00

abstract：:We have studied the amount and intracellular distribution of erythroblastic alkaline and acid phosphatase, nonspecific esterase, and N-acetyl-beta-glucosaminidase in 50 patients with acquired dyserythropoiesis. 19 morphologically normal bone marrow smears served as controls. Alkaline phosphatase was found in all contr...

journal_title：Acta haematologica

authors： Woessner S,Lafuente R,Florensa L,Sans-Sabrafen J

更新日期：1984-01-01 00:00:00

abstract：:B-cell chronic lymphocytic leukaemia (B-CLL) is characterized by a high frequency of infections, including those of viral aetiology. Previous reports have demonstrated a specific immunologic response to influenza virus vaccine in B-CLL patients with normal IgG levels. In this study, we have evaluated different immunop...

journal_title：Acta haematologica

authors： Marotta G,Bucalossi A,Galieni P,Bigazzi C,Nuti S,Valenzin PE,Bocchia M,Lauria F

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Argininemia is an autosomal recessive urea cycle disorder (UCD). Unlike other UCD, hyperammonemia is rarely seen. Patients usually present in childhood with neurological symptoms. Uncommon presentations like neonatal cholestasis or cirrhosis have been reported. Although transient elevations of liver transami...

journal_title：Acta haematologica

authors： Kiykim E,Zubarioglu T,Cansever MS,Celkan T,Häberle J,Aktuglu Zeybek AC

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Immunotherapy using recombinant human interleukin-2 (rIL-2) produces objective responses in a proportion of advanced cancer patients. While early investigators employed intravenous (i.v.) treatment regimens, recent clinical trials applied therapy schedules via subcutaneous (s.c.) injection, mostly in combina...

journal_title：Acta haematologica

authors： Schomburg A,Kirchner H,Atzpodien J

更新日期：1993-01-01 00:00:00

abstract：:The effect of 3 different detergents (Triton X-100, Lubrol WX and Nonidet) on brain thromboplastin was examined and compared with the solubilisation due to deoxycholate. The effect of deoxycholate is superior over that of the other examined detergents. Deoxycholate extracts thromboplastic activity from brain tissue to...

journal_title：Acta haematologica

authors： Bayer PM,Deutsch E

更新日期：1975-01-01 00:00:00

abstract：:Drug-induced immune hemolytic anemia is a rare but underdiagnosed and potentially fatal condition. We report a case of severe hemolytic anemia induced by cefoxitin in a 45-year-old woman admitted with menometrorrhagia. Hemoglobin levels reached a nadir of 4.7 g/dl approximately 72 h after cefoxitin initiation, and hem...

journal_title：Acta haematologica

authors： Leaf DE,Langer NB,Markowski M,Garratty G,Diuguid DL

更新日期：2010-01-01 00:00:00

abstract：:A case of Philadelphia-positive (Ph) acute lymphoblastic leukaemia (ALL) in a 40-year-old male is presented. At diagnosis, 80% of bone marrow cells were Ph. Remission with normal blood counts was achieved but the marrow became hypercellular, indicating conversion to chronic granulocytic leukaemia (GCL). The Ph clone p...

journal_title：Acta haematologica

authors： O'Brien DV,Craig JM,Secker-Walker LM,Boughton BJ

更新日期：1993-01-01 00:00:00

abstract：:In the myelodysplastic syndromes (MDS) clonogenic marrow cell culture studies have demonstrated intrinsic hemopoietic stem cell and progenitor cell abnormalities consistent with these disorders representing clonal hemopathies. Abnormal responsiveness of these cells to stimulatory and inhibitory growth factors indicate...

journal_title：Acta haematologica

authors： Greenberg PL

更新日期：1987-01-01 00:00:00

abstract：:High-dose gammaglobulin therapy for patients with idiopathic thrombocytopenic purpura (ITP), introduced by Imbach et al., was applied to 5 adults with chronic refractory ITP to investigate the mechanism of the increase in platelet counts. In 4 of the 5 cases, transient increase in platelet count was observed. Platelet...

journal_title：Acta haematologica

authors： Kurata Y,Tsubakio T,Yonezawa T,Tarui S

更新日期：1983-01-01 00:00:00

abstract：:350 patients with idiopathic thrombocytopenic purpura (ITP) aged 2/12-15 years (mean 6.3 +/- 2.7) were followed up during the period January 1st, 1975 to March 31, 1992. They constituted 40% of cases with hemorrhagic diathesis attending the Hematology/Oncology Clinic, Children's Hospital, Ain Shams University (relativ...

journal_title：Acta haematologica

authors： Khalifa AS,Tolba KA,el-Alfy MS,Gadallah M,Ibrahim FH

更新日期：1993-01-01 00:00:00

abstract：:It was confirmed that activation of the kallikrein-kinin enzyme system in cryoglobulinemia might be initiated by activation of factor XII to factor XIIa by cryoglobulin. It was also demonstrated that cryoglobulin or fibrin clots lost their ability to redissolve on warming to 37 degrees C, and consequently the lysis ti...

journal_title：Acta haematologica

authors： Kataoka K,Yamada S,Toki N

更新日期：1984-01-01 00:00:00

abstract：:A mild anemia (hemoglobin 9 g/dl) was found in a patient from Seville (Spain) with marked morphological abnormalities in the peripheral blood smear. The red cell osmotic fragility showed a mild resistance curve with a mean cell fragility (MCF) of 0.375% NaCl (normal = 0.450). Chemical Chemical and thermal instability ...

journal_title：Acta haematologica

authors： Arends T,Garlín G,Guevara JM,Amesty C,Pérez-Bández O,Lorkin PA,Lehmann H,Castillo O

更新日期：1985-01-01 00:00:00