Cervical spinal MRI in a patient with a vagus nerve stimulator (VNS).

abstract：:CYP2C9 is mainly responsible for the metabolic clearance of phenytoin and (S)-warfarin. We have shown previously that mutations in the CYP2C9 gene are associated with diminished metabolism of (S)-warfarin, and so we have now studied the metabolism of phenytoin to its primary inactive metabolite, (S)-pHPPH, by these mu...

journal_title：Epilepsy research

authors： Rettie AE,Haining RL,Bajpai M,Levy RH

更新日期：1999-07-01 00:00:00

abstract：:In order to assess the chloride channel gene CLCN2 as a candidate susceptibility gene for childhood absence epilepsy, parametric and non-parametric linkage analysis was performed in 65 nuclear pedigrees. This provided suggestive evidence for linkage with heterogeneity: NPL score=2.3, p<0.009; HLOD=1.5, alpha=0.44. Mut...

journal_title：Epilepsy research

authors： Everett K,Chioza B,Aicardi J,Aschauer H,Brouwer O,Callenbach P,Covanis A,Dooley J,Dulac O,Durner M,Eeg-Olofsson O,Feucht M,Friis M,Guerrini R,Heils A,Kjeldsen M,Nabbout R,Sander T,Wirrell E,McKeigue P,Robinson R,

更新日期：2007-07-01 00:00:00

abstract：PURPOSE:Hippocampal sclerosis (HS) is the most common pathology in mesial temporal lobe epilepsy (MTLE). There are a few reports concerning prognosis in patients with MTLE-HS treated medically. The study was carried out to determine the clinical risk factors affecting prognosis. METHODS:We enrolled 287 patients with M...

journal_title：Epilepsy research

authors： Varoglu AO,Saygi S,Acemoglu H,Ciger A

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVE:Approximately 80% of glioma patients will experience at least one seizure activity during the course of the disease, and because the etiology of glioma-related seizure is most likely multifactorial and complex, it remains poorly understood. MicroRNAs are a class of small noncoding RNAs that function as critic...

journal_title：Epilepsy research

authors： Yuan Y,Xiang W,Yanhui L,Ruofei L,Yunhe M,Jiewen L,Qing M

更新日期：2016-11-01 00:00:00

abstract：:The effects of a novel anticonvulsant, zonisamide (3-sulfamoylmethyl-1,2-benzisoxazole), on photically induced seizures were studied in the lateral geniculate-kindled cat. Zonisamide was found to reduce the behavioral severity of seizure responses to photic stimulation in a dose-related manner. This anticonvulsant eff...

journal_title：Epilepsy research

authors： Wada Y,Hasegawa H,Yamaguchi N

更新日期：1990-11-01 00:00:00

abstract：PURPOSE:In patients with left temporal lobe epilepsy (TLE) due to hippocampal sclerosis (HS) decreased naming ability is common, suggesting a critical role for the medial left temporal lobe in this task. We investigated the integrity of language networks with functional MRI (fMRI) in controls and TLE patients. EXPERIM...

journal_title：Epilepsy research

authors： Bonelli SB,Powell R,Thompson PJ,Yogarajah M,Focke NK,Stretton J,Vollmar C,Symms MR,Price CJ,Duncan JS,Koepp MJ

更新日期：2011-08-01 00:00:00

abstract：PURPOSE:Ictal magenetoencephalographic (MEG) discharges convey significant information about ictal onset and propagation, but there is no established method for analyzing ictal MEG. This study sought to clarify the usefulness of time-frequency analyses using short-time Fourier transform (STFT) for ictal onset and propa...

journal_title：Epilepsy research

authors： Yagyu K,Takeuchi F,Shiraishi H,Nakane S,Sueda K,Asahina N,Kohsaka S,Umeoka S,Usui N,Baba K,Saitoh S

更新日期：2010-08-01 00:00:00

abstract：:It has previously been suggested that abnormalities in cardiac repolarization (QTc lengthening and shortening) are more likely to accompany seizures with hypoxemia and may be involved in sudden unexpected death in epilepsy (SUDEP). Accordingly, we evaluated for associations between peri-ictal QTc changes and hypoxemia...

journal_title：Epilepsy research

authors： Moseley BD,Britton JW

更新日期：2014-07-01 00:00:00

abstract：:The effects of GABA uptake inhibitors, SKF 89976A and SKF 100330A, on recurrent inhibition were studied in the rat hippocampal slice preparation by the antidromic-orthodromic stimulation test. Population spikes evoked orthodromically by stimulation of the stratum radiatum and recorded in the CA1 pyramidal cell body la...

journal_title：Epilepsy research

authors： Capek R,Esplin B

更新日期：1993-10-01 00:00:00

abstract：PURPOSE:To determine the minimum enrollment duration for identifying incident cases of epilepsy in administrative data. METHODS:We performed a retrospective dynamic cohort study using Ohio Medicaid data from 1992 to 2006 to identify a total of 5037 incident epilepsy cases who had at least 1 year of follow-up prior to ...

journal_title：Epilepsy research

authors： Bakaki PM,Koroukian SM,Jackson LW,Albert JM,Kaiboriboon K

更新日期：2013-09-01 00:00:00

abstract：:This study was carried out to evaluate Synthetic Aperture Magnetometry-kurtosis (SAM(g(2))), a spatially filtered source localization technique in magnetoencephalography (MEG), for identification of epileptogenic areas of focal cortical dysplasia (FCD). Three children with FCD were investigated to localize the ictal o...

journal_title：Epilepsy research

authors： Ishii R,Canuet L,Ochi A,Xiang J,Imai K,Chan D,Iwase M,Takeda M,Snead OC 3rd,Otsubo H

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:Idiopathic epilepsy (IE) is a syndrome that comprises epilepsy only, with no underlying structural brain lesion or other neurological signs or symptoms. Numerous studies have shown that genetic factors play an important role in IE. IE is a common disease in the Chinese Han population. However, the genetic ep...

journal_title：Epilepsy research

authors： Li M,Heng X,Tao R,Liu J,Zhang L,Sun X,Wang L,Wu Q,Che F,Xue F

更新日期：2012-02-01 00:00:00

abstract：:Pharmacoresistant mesial temporal lobe epilepsy (mTLE) represents the major indication for epilepsy surgery. Since epilepsy surgery is an elective treatment option, preserving cognition is a high priority. Given the essential role of temporomesial structures in declarative long-term memory formation, surgical treatmen...

journal_title：Epilepsy research

authors： Witt JA,Hoppe C,Helmstaedter C

更新日期：2018-05-01 00:00:00

abstract：INTRODUCTION:Recent ILAE classification defined focal cortical dysplasia (FCD) patients with accompanying epileptic lesions as a separate group. We investigated data of patients with sole FCD lesions regarding long-term seizure outcome and different characteristics of FCD type 1 and type 2 patients. METHODS:Eighty chi...

journal_title：Epilepsy research

authors： Isler C,Kucukyuruk B,Ozkara C,Gunduz A,Is M,Tanriverdi T,Comunoglu N,Oz B,Uzan M

更新日期：2017-10-01 00:00:00

abstract：PURPOSE:To identify consistent results of voxel-based morphometry (VBM) studies in unilateral refractory temporal lobe epilepsy (TLE). METHODS:Whole-brain VBM studies comparing refractory TLE patients with healthy controls (HC) were systematically searched in PubMed, ISI Web of Science, Embase, and Medline databases f...

journal_title：Epilepsy research

authors： Li J,Zhang Z,Shang H

更新日期：2012-02-01 00:00:00

abstract：:The ketogenic diet (KD) remains a therapy in search of explanation although it is an established treatment of intractable epilepsy. Recent studies suggest that the KD may be both anticonvulsant and antiepileptogenic. Epileptic seizures have been shown to stimulate the proliferation rate of neuronal progenitor cells in...

journal_title：Epilepsy research

authors： Kwon YS,Jeong SW,Kim DW,Choi ES,Son BK

更新日期：2008-02-01 00:00:00

abstract：OBJECTIVE:Recent studies have suggested that the early introduction of a ketogenic diet (KD) could improve seizure control in myoclono-astatic epilepsy (MAE). This multicenter study sought to identify the benefits of KD use on seizure control and epilepsy and on developmental outcomes in children with resistant MAE. M...

journal_title：Epilepsy research

authors： Stenger E,Schaeffer M,Cances C,Motte J,Auvin S,Ville D,Maurey H,Nabbout R,de Saint-Martin A

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:In many parts of eastern Asia, rice is a dietary staple and therefore the ketogenic diet (KD) can be difficult to administer. The aim of this study was to assess the long-term effectiveness and tolerability of the classical KD using a 2:1 ratio of fat to protein plus net carbohydrates, which is lower than th...

journal_title：Epilepsy research

authors： Lee HF,Chi CS,Liao JH

更新日期：2018-11-01 00:00:00

abstract：:We analyzed preoperative ictal SPECT results from 18 frontal lobe epilepsy patients who underwent epilepsy surgery (mean age 22.9 years). Seizure onset at implanted subdural electrodes was defined as the epileptic focus in 16 of 18 patients. In two additional patients, the resected area on postoperative magnetic reson...

journal_title：Epilepsy research

authors： Fukuda M,Masuda H,Honma J,Kameyama S,Tanaka R

更新日期：2006-02-01 00:00:00

abstract：:Activation of group I metabotropic glutamate receptors (mGluRs) produces a long-lasting change in hippocampal excitability that persists in the absence of an agonist. Exposure to the group I mGluR agonist dihydroxyphenylglycine (DHPG) results in the induction of spontaneously occurring epileptiform activity in the CA3...

journal_title：Epilepsy research

authors： Karr L,Rutecki PA

更新日期：2008-09-01 00:00:00

abstract：:The objective of the study was to explore clinical, electroencephalography (EEG), neuropsychological features and prognosis of myoclonic-astatic epilepsy (MAE). Of 327 children aged between 1 and 9 years with a diagnosis of generalized epilepsy followed between 2000 and 2008, 18 (5.5%) had MAE. Male significantly pred...

journal_title：Epilepsy research

authors： Trivisano M,Specchio N,Cappelletti S,Di Ciommo V,Claps D,Specchio LM,Vigevano F,Fusco L

更新日期：2011-11-01 00:00:00

abstract：PURPOSE:Intracranial EEG in patients with lesional lateral temporal lobe epilepsy is rarely reported. Therefore, the number of patients with seizures arising independently from ipsilateral mesial structures or contralateral hemisphere has not been clarified. We analyzed the intracranial EEG of cases with localized lesi...

journal_title：Epilepsy research

authors： Usui N,Mihara T,Baba K,Matsuda K,Tottori T,Umeoka S,Nakamura F,Terada K,Usui K,Inoue Y

更新日期：2008-01-01 00:00:00

abstract：PURPOSE:We performed this study to evaluate the frequency, types, and ictal electroencephalography (EEG) findings of coexisting seizures in patients with infantile spasms at the onset of spasms. We also evaluated the effect of coexisting seizures on short-term seizure control. METHODS:We retrospectively reviewed the l...

journal_title：Epilepsy research

authors： Kim H,Lee JH,Ryu HW,Lim BC,Chae JH,Choi J,Kim KJ,Hwang YS,Hwang H

更新日期：2012-08-01 00:00:00

abstract：:Brain glucose transport is dependent on glucose transporter 1 (GLUT1), encoded by the solute carrier family 2 member 1 (SLC2A1) gene. Mutations in SLC2A1 cause GLUT1 deficiency which is characterized by a broad spectrum of neurological phenotypes including generalized epilepsy, motor disorders, developmental delay and...

journal_title：Epilepsy research

authors： Peeraer A,Damiano JA,Bellows ST,Scheffer IE,Berkovic SF,Mullen SA,Hildebrand MS

更新日期：2017-07-01 00:00:00

abstract：PURPOSE:To evaluate the efficacy and safety of stiripentol as add-on therapy in Japanese patients with Dravet syndrome treated with clobazam (CLB) and valproate (VPA). METHODS:In this open-label study, patients aged 1-30 years entered a 4-week baseline phase, followed by a 4-week stiripentol dose-adjustment and 12-wee...

journal_title：Epilepsy research

authors： Inoue Y,Ohtsuka Y,STP-1 Study Group.

更新日期：2014-05-01 00:00:00

abstract：RATIONALE AND PURPOSE:Preliminary reports have suggested a possible 'aetiology-specific' efficacy of tiagabine (TGB) in patients with drug-resistant partial epilepsy (DRPE) related to cerebral glial tumors (GTs). This efficacy should be related to selective blocking of GAT-1 transporter by TGB. We presented our open-la...

journal_title：Epilepsy research

authors： Striano S,Striano P,Boccella P,Nocerino C,Bilo L

更新日期：2002-03-01 00:00:00

abstract：:Interictal blood flow single photon emission computed tomography (SPECT) has been considered to be of limited value in the investigation of patients with partial epilepsies. Newer SPECT technologies using brain dedicated multiple detector systems have not been fully evaluated. To study the usefulness of an optimized S...

journal_title：Epilepsy research

authors： Schmitz EB,Costa DC,Jackson GD,Moriarty J,Duncan JS,Trimble MR,Ell PJ

更新日期：1995-06-01 00:00:00

abstract：:Ketamine, a noncompetitive N-methyl-D-aspartate receptor (NMDAR) antagonist, used as an anesthetic has been reported to induce seizures both in humans and baboons predisposed to epilepsy. In this study, we aimed to characterize the acute effects of ketamine on scalp (sc-EEG) and intracranial EEG (ic-EEG) in the baboon...

journal_title：Epilepsy research

authors： Gowda S,Szabó CÁ

更新日期：2019-08-01 00:00:00

abstract：:A combination of temporo-limbic hyperperfusion and extratemporal hypoperfusion was observed during complex partial seizures (CPS) in temporal lobe epilepsy (TLE). To investigate the clinical correlate of perfusion changes in TLE, we analyzed focal seizures of increasing severity using voxel-based analysis of ictal SPE...

journal_title：Epilepsy research

authors： Chassagnon S,Namer IJ,Armspach JP,Nehlig A,Kahane P,Kehrli P,Valenti MP,Hirsch E

更新日期：2009-08-01 00:00:00

abstract：:In the brain, injury-induced gliosis and axonal sprouting have been regarded as age-dependent repairing processes with, unfortunately, epileptogenic effects. The present study examines whether brains injured at different developmental stages become more or less susceptible to experimentally-induced status epilepticus....

journal_title：Epilepsy research

authors： Setkowicz Z,Janeczko K

更新日期：2003-03-01 00:00:00