Abstract：
:Apert syndrome is 1 of the 5 craniosynostosis syndromes that shore clinical features and are caused by allelic mutations in the fibroblast growth factor receptor 2 (FGFR2) gene. The purpose of this paper was to report a case of Apert syndrome, with particular emphasis on craniofacial and genetic features, in a 5-year-old female patient. The patient presented with several craniofacial deformities, including severe brachycephaly, midface hypoplasio, flat forehead, proptosis, hypertelorism, and short nose with a bulbous tip. Syndactylies of the hands and feet were also observed. Intraoral findings included arched palate with pseudocleft in the midline, upper lip with symmetric depression resembling pseudoclefts, severe malocclusion, and several decoyed teeth. DNA sequence and restriction enzyme analysis showed a G to C transversion, resulting in a serine to tryptophan amino acid substitution at position 252 (S252W). Identification of the clinical features associated with mutation analysis is important to correctly diagnose Apert syndrome and distinguish it from other clinically similar craniosynostosis syndromes.
journal_name
Pediatr Dentjournal_title
Pediatric dentistryauthors
Martelli H Jr,Paranaíba LM,de Miranda RT,Orsi J Jr,Coletta RDsubject
Has Abstractpub_date
2008-11-01 00:00:00pages
464-8issue
6eissn
0164-1263issn
1942-5473journal_volume
30pub_type
杂志文章abstract：PURPOSE:The high-viscosity consistency of glass ionomer cement (GIC) contributes to its inappropriate adaptation, while the material's premature exposure to humidity decreases its mechanical properties. This study's purposes were to: (1) investigate approximal atraumatic restorative treatment (ART) restorations' surviv...
journal_title：Pediatric dentistry
pub_type： 杂志文章,多中心研究,随机对照试验
doi：
更新日期：2016-01-01 00:00:00
abstract：:Epidermolysis bullosa (EB) is a clinically diverse group of conditions characterized by skin fragility and, in certain types, marked dental involvement. The purpose of this study was to determine the prevalence of dental caries in EB and control populations. Healthy individuals and participants from the Southern Clini...
journal_title：Pediatric dentistry
pub_type： 杂志文章
doi：
更新日期：1994-11-01 00:00:00
abstract：:Panel I comprised of pediatric dentists, an attorney, child psychologists, parents, a specialist in early childhood education, and a pediatrician. The purpose of this panel was to discuss: (1) 8 questions that dealt with the appropriateness and effectiveness of current behavior management techniques; (2) the scientifi...
journal_title：Pediatric dentistry
pub_type： 杂志文章
doi：
更新日期：2004-03-01 00:00:00
abstract：:In this study, a possible new syndrome affecting 18 members of a family spanning 4 generations is described. The main features include palmoplantar hyperkeratosis, proportionate short stature, facial dysmorphism, clinodactyly, epilepsy, deafness, and hypodontia. This syndrome is inherited in an autosomal dominant mann...
journal_title：Pediatric dentistry
pub_type： 杂志文章
doi：
更新日期：1989-06-01 00:00:00
abstract：:1. Of the hospital programs, 10 of 17 (41%) reported no funding requirement while only 5 of 33 (15%) school based programs reported no funding requirement. 2. Departmental funds were identified most often (N = 28) and ranked number one most often (N = 16) as the funding source for graduate student research. 3. The ave...
journal_title：Pediatric dentistry
pub_type： 杂志文章
doi：
更新日期：1997-05-01 00:00:00
abstract：:Rapid palatal expansion (RPE) causes separation of the lateral halves of the palate and traditionally has used four maxillary teeth as anchorage. The purpose of this study was to introduce a rapid palatal expander that requires only two anchor teeth (two-point RPEe) and to compare the expansion obtained with that from...
journal_title：Pediatric dentistry
pub_type： 杂志文章
doi：
更新日期：1990-04-01 00:00:00
abstract：:The purpose of this case report was to describe the successful long-term conservative management of a root-fractured permanent maxillary right central incisor in an 8-year-old patient. After the initial approach of splinting the traumatized tooth, the patient was followed on a regular basis for 15 years. Clinically, ...
journal_title：Pediatric dentistry
pub_type： 杂志文章
doi：
更新日期：2012-03-01 00:00:00
abstract：PURPOSE:The purpose of this study was to investigate the impact of gastroesophageal reflux disease (GERD) on dental erosion (DE) in children and analyze the association between dental erosion and diet, oral hygiene, and sociodemographic characteristics. METHODS:This case-control study encompassed 43 two- to 14-year-ol...
journal_title：Pediatric dentistry
pub_type： 杂志文章
doi：
更新日期：2016-01-01 00:00:00
abstract：PURPOSE:The purpose of the investigation was to determine factors associated with dental erosion in a group of schoolchildren in Queensland, Australia. METHODS:Dental examinations were carried out on 714 children aged 5.5 to 14.6 years from 8 randomly selected Australian schools. A total of 3,165 primary and 2,976 per...
journal_title：Pediatric dentistry
pub_type： 杂志文章
doi：
更新日期：2007-01-01 00:00:00
abstract：PURPOSE:The purpose of this study was to describe caretakers' self-selected pediatric oral health goals, self-reported compliance, perceived self-efficacy, and perceived barriers to goal accomplishment. The effect of self-management plans on recall attendance was also evaluated. METHODS:Fifty caretaker-patient pairs w...
journal_title：Pediatric dentistry
pub_type： 杂志文章
doi：
更新日期：2017-07-15 00:00:00
abstract：: Purpose: To determine the prevalence of developmental defects of enamel (DDE) among American Indian (AI) children and whether DDE are associated with caries experience and rehabilitative treatment under general anesthesia (GA). Methods: ...
journal_title：Pediatric dentistry
pub_type： 杂志文章
doi：
更新日期：2020-03-15 00:00:00
abstract：:Increasing information emphasize the relevance of the prevention, early diagnosis and early treatment of periodontal diseases in children. In order to avoid erroneous diagnosis and unnecessary treatments, the pediatric dentist is required to differentiate between pathologic processes and normal changes that take place...
journal_title：Pediatric dentistry
pub_type： 杂志文章,评审
doi：
更新日期：1999-05-01 00:00:00
abstract：:Ectopic eruption of permanent first molars occurs infrequently and causes some resorption of the adjacent primary second molar. The primary second molar can be used as an anchor tooth for the Halterman appliance to disimpact the permanent first molar, provided root resorption is not extreme. A modification of the Halt...
journal_title：Pediatric dentistry
pub_type： 杂志文章
doi：
更新日期：2007-07-01 00:00:00
abstract：PURPOSE:The present study was undertaken to determine the presence of 3 periodontopathic bacteria in the supragingival plaques of 3- to 16-year-old children with different oral health conditions. METHODS:DMFT and dft, PMA index (P=papillary gingivitis, M=marginal gingivitis, and A=attached gingivitis), OHI (oral hygie...
journal_title：Pediatric dentistry
pub_type： 杂志文章
doi：
更新日期：2003-03-01 00:00:00
abstract：:This paper describes the development of dentin bonding systems, and describes the current strategies for bonding composite resin materials to dentin. Two main strategies are available--total-etch or self-etch--and each has unique advantages and disadvantages. For each category, simplified systems that reduce the numbe...
journal_title：Pediatric dentistry
pub_type： 杂志文章,评审
doi：
更新日期：2002-09-01 00:00:00
abstract：PURPOSE:The objective of this pilot study was to determine the prevalence of coronal dental caries among children with different genetic sensitivity levels of taste, as determined by 6-n-propylthiouracil (PROP). METHODS:Coronal caries and restorations in permanent and primary dentition were evaluated in 150 healthy sc...
journal_title：Pediatric dentistry
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
abstract：:Present methods of assessing pulp vitality (electric and thermal testing) are of limited use with children, often resulting in false positive or false negative results. Pulse oximetry is a proven, atraumatic method of measuring vascular health by evaluating oxygen saturation (SaO2). This pilot study explores the use o...
journal_title：Pediatric dentistry
pub_type： 杂志文章
doi：
更新日期：1999-03-01 00:00:00
abstract：:Improving the oral health of children and adults requires not only that patients receive high quality clinical care, but also that they gain access to the dental office in the first place. Access to care can be promoted among many systems of care, both within and outside of dentistry. The Association of State and Terr...
journal_title：Pediatric dentistry
pub_type： 杂志文章
doi：
更新日期：2007-03-01 00:00:00
abstract：:The purpose of this study was to evaluate the effect of acid conditioning and occlusal sealant on microbial colonization of pit and fissures submitted to ameloplasty or left intact. Human enamel blocks containing fissures prepared from the occlusal surfaces of unerupted third molars were implanted in occlusal fillings...
journal_title：Pediatric dentistry
pub_type： 杂志文章
doi：
更新日期：1993-03-01 00:00:00
abstract：PURPOSE:The purpose of this study was to assess after-hours practice characteristics of pediatric dentists (PDs) and general dentists (GDs) and determine how patients-of-record obtain after-hours emergency dental care. METHODS:A 29-item survey was electronically distributed to PDs and GDs in North Carolina in Septembe...
journal_title：Pediatric dentistry
pub_type： 杂志文章
doi：
更新日期：2017-03-15 00:00:00
abstract：PURPOSE:The objective of this study was to explore dentists', dental hygienists', dental students', and dental hygiene students' knowledge about their professional responsibilities concerning suspected child abuse and their professional experiences with this issue. METHODS:Questionnaire data were collected from 220 ge...
journal_title：Pediatric dentistry
pub_type： 杂志文章
doi：
更新日期：2006-09-01 00:00:00
abstract：:The surgical approach has been the predominate mode of caries management for the past 150 years. Dentistry has, however, in recent years moved toward an antibiotic/antimicrobial model of disease management. This approach, however, raises serious questions: (1) do the antibiotic/antimicrobial agents (chlorhexidine, pov...
journal_title：Pediatric dentistry
pub_type： 杂志文章
doi：
更新日期：2006-03-01 00:00:00
abstract：:This report presents a review of results from 2370 biopsies of patients up to 20 years of age received over 11 years in the biopsy service at the University of Illinois at Chicago. The computerized data were retrieved and compiled for site, age, sex, race, and diagnosis of the biopsies. The lesions were divided into 1...
journal_title：Pediatric dentistry
pub_type： 杂志文章
doi：
更新日期：1993-05-01 00:00:00
abstract：:Teething as a disease entity has been diminished from its 19th century status as the major cause of infant mortality to its modest position today as a "waste basket" diagnosis. If past proves to be prologue, it will diminish further as more credible causes for undifferentiated fevers and other complaints are found. Th...
journal_title：Pediatric dentistry
pub_type： 历史文章,杂志文章
doi：
更新日期：1994-05-01 00:00:00
abstract：: Purpose: The purpose of this study was to assess the survival probability of zirconia crowns (ZCs) on primary maxillary incisors placed in children diagnosed with severe early childhood caries at 12-, 24-, and 36-month follow-up visits in a university pediatric dental clin...
journal_title：Pediatric dentistry
pub_type： 杂志文章
doi：
更新日期：2019-09-15 00:00:00
abstract：:Patients with autism spectrum disorders (ASDs) may have difficulty tolerating conventional dental treatment due to aberrant sensory responsiveness. The purpose of this report was to describe the successful treatment of obstructive sleep apnea (OSA) in a nonverbal 20-year-old male patient with ASD using a dental applia...
journal_title：Pediatric dentistry
pub_type： 杂志文章
doi：
更新日期：2014-11-01 00:00:00
abstract：PURPOSE:This study's purpose was to examine the current knowledge, attitudes, and experiences related to infant oral health for dental and medical providers in Virginia. METHODS:A survey of infant oral health care was sent to: (a) 300 randomly selected general dentists; (b) 300 randomly selected pediatricians; and (c)...
journal_title：Pediatric dentistry
pub_type： 杂志文章
doi：
更新日期：2008-03-01 00:00:00
abstract：:The treatment options of enamel dentin crown fractures with pulpal exposure in the primary dentition traditionally consist of direct pulp capping, pulpotomy, pulpectomy, or extraction. Many clinicians disagree on the most appropriate treatment, and individual preferences exist within dentistry. Partial pulpotomy, also...
journal_title：Pediatric dentistry
pub_type： 杂志文章
doi：
更新日期：2003-05-01 00:00:00
abstract：:Klippel-Trenaunay-Weber syndrome is characterized by limb hypertrophy, varicose veins, and vascular nevus. The orofacial manifestations include early eruption of permanent teeth and hemifacial hypertrophy. This 5-year-old male patient had facial asymmetry, limb abnormalities, and a thumb-sucking habit. Cephalometric a...
journal_title：Pediatric dentistry
pub_type： 杂志文章,评审
doi：
更新日期：1994-05-01 00:00:00
abstract：:The prevalence of gingival overgrowth secondary to the administration of cyclosporin (CS) is currently reported between 8 and 70%, depending upon the source. Information concerning pediatric patients is limited. To determine the prevalence of the condition in a population of children, 26 pediatric liver or kidney tran...
journal_title：Pediatric dentistry
pub_type： 杂志文章
doi：
更新日期：1994-01-01 00:00:00
