Effector and memory CD4+ and CD8+ T cells in the chronic infection process.

Abstract:

:T cell memory in comparison with B cell memory is not well understood. This review focuses on CD8+ and CD4+ memory T cells. In this article we try to define memory cells and also present models of memory T cells formation. We would also like to delineate their differentiation into distinct subsets. Long-lived memory T cells consist in two main subsets: TCM and TEM. Recent studies have shown that not all cells considered to be memory cells differentiate into TCM and TEM, but a small proportion of theses cells exhibit naive cells phenotype. Memory T cells constitute a heterogeneous population of cells. In this study we lay stress on characteristic of main memory T cells subsets and their alleged participation in immune response upon reexposure to the Ag.

authors

Ojdana D,Safiejko K,Lipska A,Radziwon P,Dadan J,Tryniszewska E

doi

10.2478/v10042-008-0077-5

subject

Has Abstract

pub_date

2008-01-01 00:00:00

pages

413-7

issue

4

eissn

0239-8508

issn

1897-5631

pii

RN4160X7046H5304

journal_volume

46

pub_type

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