Abstract：
:The study included 61 patients (35 men and 26 women) ages 47 to 74 in whom a primary liver cancer was diagnosed or neoplastic metastases to the liver were confirmed in the course of a cancer of the stomach or the large bowel. In each patient the endogenous serum diazepam concentration (ESDC) was estimated chromatographically and the results obtained were compared to selected clinical traits such as the magnitude and number of neoplastic changes and their location in the liver parenchyma, the histological form of the tumor and the primary location of the cancer in the case of neoplasms of the alimentary canal. The determination of the ESDC was also carried out in a control group made up of voluntary blood donors. Neither group examined received any medication belonging to the benzodiazepine group. From the results of the tests conducted it was confirmed that the average ESDC of patients with liver neoplasms was 65 times higher than that of the control group. Simultaneously, however, in patients with a primary liver cancer the average endogenous concentration was higher than in patients with neoplastic metastases to that organ and this was statistically significant. The location in the hepatic parenchyma of the neoplastic change as well as the primary location of the cancer remained without a statistically significant influence in the changes of ESDC. It was moreover shown that significantly high ESDC were associated in the liver mainly with increased neoplastic growth (above 3 cm in diameter) and with multiple spread (5 focuses and more).
journal_name
Folia Histochem Cytobioljournal_title
Folia histochemica et cytobiologicaauthors
Kopański Z,Sliwińska M,Piekoszewski W,Habiniak J,Wojewoda T,Wojewoda A,Schlegel-Zawadzka M,Sibiga Wsubject
Has Abstractpub_date
2001-01-01 00:00:00pages
124-6eissn
0239-8508issn
1897-5631journal_volume
39 Suppl 2pub_type
杂志文章abstract：:On the basis of radioactivity of interphase cells in the antheridial filaments of Chara vulgaris after a 20 min. incubation with 3H-uridine and after a 40 min. postincubation the activity of synthesis and transport of newly synthesized RNA has been studied in different-sized nucleoli. Investigations of their ultrastru...
journal_title：Folia histochemica et cytobiologica
pub_type： 杂志文章
doi：
更新日期：1985-01-01 00:00:00
abstract：:Early recognition of prostate cancer (PC) based on biological markers could be helpful in identification of differences in benign and malignant lesions and facilitate further precise indication for more aggressive treatment. Therefore, the aim of our study was to assess expression of hTERT (human telomerase reverse tr...
journal_title：Folia histochemica et cytobiologica
pub_type： 杂志文章
doi：10.5603/FHC.2013.0010
更新日期：2013-01-01 00:00:00
abstract：:The increased ambient temperature affects the function of hypothalamic-pituitary-adrenal (HPA) axis. Since the correlation among vasopressin (VP), adrenocorticotropic hormone (ACTH) and corticosterone (CORT) responses to various stressors have been long recognized, the aim of this study was to reveal the aforementione...
journal_title：Folia histochemica et cytobiologica
pub_type： 杂志文章
doi：10.2478/v10042-010-0071-6
更新日期：2010-12-01 00:00:00
abstract：INTRODUCTION:Sucla2, a β subunit of succinyl coenzyme A synthase, is located in the mitochondrial matrix. Sucla2 catalyzes the reversible synthesis of succinate and adenosine triphosphate (ATP) in the tricarboxylic acid cycle. Sucla2 expression was found to be correlated with the capacitation of boar spermatozoa. We ha...
journal_title：Folia histochemica et cytobiologica
pub_type： 杂志文章
doi：10.5603/FHC.a2016.0020
更新日期：2016-01-01 00:00:00
abstract：:Nuclear bodies (NBs) are intranuclear structures described in normal and pathologically altered cells of humans and animals. The NBs are 0.3-1.5 microns round structures. Their function is unknown. In the present paper, we describe NBs in the nuclei of the conjunctiva epithelial cells in one patient with cicatricial p...
journal_title：Folia histochemica et cytobiologica
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：:The internal space of the antheridium in Chara vulgaris L. is filled with the PAS-positive mucilage which is of pectic nature. Morphometric and cytophotometric measurements on the semithin sections indicate that the concentration and amount of PAS-positive polysaccharides: 1) increase during the time of antheridial gr...
journal_title：Folia histochemica et cytobiologica
pub_type： 杂志文章
doi：
更新日期：1991-01-01 00:00:00
abstract：:The development of central serotoninergic neurons has been investigated with immunohistochemical techniques using the indirect peroxidase-antiperoxidase (PAP) method in 16-and 19-day-old rat embryos, in 1, 10 and 26 days old young and in adult animals. Immunoreactive neurons were present on embryonic day 16 in the sub...
journal_title：Folia histochemica et cytobiologica
pub_type： 杂志文章
doi：
更新日期：1987-01-01 00:00:00
abstract：:The death and phagocytosis of the stomach mucoid epithelium cells in 2-8 day old mice were investigated in relation to the state of cell differentiation and the cell age. The autoradiographic determination of 3H-thymidine and cytochemical demonstration of neutral mucosubstances in secretory granules (TA-UA and PA-TCH-...
journal_title：Folia histochemica et cytobiologica
pub_type： 杂志文章
doi：
更新日期：1994-01-01 00:00:00
abstract：INTRODUCTION:Ghrelin, an appetite-stimulating hormone secreted by the endocrine cells of the gastrointestinal (GI) tract, has recently been shown to affect the function of the cardiovascular system. This study aimed to assess the number and morphology of ghrelin-immunopositive (GhrIP) cells in the gastrointestinal trac...
journal_title：Folia histochemica et cytobiologica
pub_type： 杂志文章
doi：10.5603/FHC.a2016.0023
更新日期：2016-01-01 00:00:00
abstract：:Induction of the P21 protein is an integral part of cell growth arrest associated with the cellular response to senescence or damage. Changes in the P21 protein level are often observed in tumour cells and it is suggested, that they correlate with malignancy. We studied the P21 gene expression at the mRNA level in bio...
journal_title：Folia histochemica et cytobiologica
pub_type： 杂志文章
doi：
更新日期：2001-01-01 00:00:00
abstract：:Ventral tegmental area (VTA) is a heterogeneous group of dopaminergic cells which contains interfascicular (IF), parabrachial (PBP) and rostral linear (RLi) nuclei. Neurons of this area are involved in the regulation of motor and motivational aspects of behavior and reveal high neuronal plasticity. Among many various ...
journal_title：Folia histochemica et cytobiologica
pub_type： 杂志文章
doi：
更新日期：2004-01-01 00:00:00
abstract：:In root meristems of 3 species (Secale cereale L., Vicia faba L. subsp. minor, Allium cepa L.) the durations of cell cycles and their phases were calculated using 3H-thymidine labelling. In the above species and in Helianthus annuus L. (parameters of the cell cycle determined earlier) the G1 and G2 phase durations wer...
journal_title：Folia histochemica et cytobiologica
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：:The present study deals with immunohistochemical localization of S-100 protein in mouse, bank vole and pine vole testis and epididymis. S-100 protein immunoreactivity was observed in the endothelia of capillaries and lymphatic sinusoids of pine vole testis. A reaction to S-100 protein of the same intensity as that not...
journal_title：Folia histochemica et cytobiologica
pub_type： 杂志文章
doi：
更新日期：2000-01-01 00:00:00
abstract：:The effectiveness of the long acting somatostatin analogues like octreotide and lanreotide depends on the expression of specific somatostatin receptors on the target cells. The immunohistochemical method performed on surgically removed tumors searches the expression of receptors at the level of receptor protein and gi...
journal_title：Folia histochemica et cytobiologica
pub_type： 杂志文章
doi：10.2478/v10042-008-0103-7
更新日期：2010-01-01 00:00:00
abstract：:Tyrosine phosphorylation of numerous proteins is one of the earliest events detectable during Fcgamma receptor-mediated phagocytosis. We demonstrate that IgG-coated particles associated with the surface of macrophages are enriched with numerous tyrosine-phosphorylated proteins. During particle internalization the prot...
journal_title：Folia histochemica et cytobiologica
pub_type： 杂志文章
doi：
更新日期：2002-01-01 00:00:00
abstract：:The expression of proliferating cell nuclear antigen (PCNA) correlates to cell proliferation and for this reason it is commonly considered as one of proliferation markers. Since proliferation rate is an important factor determining the tumor aggressiveness, the evaluation of PCNA index (the percentage of PCNA-immunopo...
journal_title：Folia histochemica et cytobiologica
pub_type： 杂志文章
doi：
更新日期：2006-01-01 00:00:00
abstract：:Cancer procoagulant activity in the blood serum of patients with oesophagal, gastric and colorectal cancer was evaluated before and after the tumour removal. Cancer procoagulant activity was significantly higher before the operation in comparison to the control group and was reduced after a total operative procedure, ...
journal_title：Folia histochemica et cytobiologica
pub_type： 杂志文章
doi：
更新日期：2001-01-01 00:00:00
abstract：:The effect of quercetin and heat shock on the Hsp72 level and distribution in HeLa cells was studied by Western blotting, indirect immunofluorescence and immunogold electron microscopy. In control cells and after quercetin treatment, Hsp72 was located both in the cytoplasm and in the nucleus in comparable amounts. Aft...
journal_title：Folia histochemica et cytobiologica
pub_type： 杂志文章
doi：
更新日期：2005-01-01 00:00:00
abstract：:The fossil dinosaur bone material, 80 million years old was studied. Samples for analysis were prepared with specially elaborated methods. Images obtained in the light, transmission electron, and scanning electron microscopes revealed the spatial distribution of the osteocytes lying near and far from the vascular cana...
journal_title：Folia histochemica et cytobiologica
pub_type： 杂志文章
doi：
更新日期：1984-01-01 00:00:00
abstract：:It was demonstrated by a cytochemical method that the calcium-dependent ATPase was present in the germinating pollen grain. Immediately after hydration the enzyme was observed in the pollen plasmalemma. During germination, the chief sites of the enzyme activity were the plasmalemma around the aperture site and the cis...
journal_title：Folia histochemica et cytobiologica
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：INTRODUCTION:Testicular function in the sand rodent Psammomys obesus is subjected to seasonal alternations with a trigger of spermatogenesis in winter and a total quiescence which extends from late spring to summer. The aim of this study was to investigate the distribution of b-endorphin in the testis at the period of ...
journal_title：Folia histochemica et cytobiologica
pub_type： 杂志文章
doi：10.5603/FHC.a2016.0013
更新日期：2016-01-01 00:00:00
abstract：:The aim of this study was to assess the impact of laparoscopic gastric banding and laparoscopic sleeve gastrectomy on the concentration of ghrelin, insulin, glucose, triglycerides, total and HDL-cholesterol, as well as AST and ALT levels in plasma in patients with obesity. The research includes 200 patients operated u...
journal_title：Folia histochemica et cytobiologica
pub_type： 杂志文章
doi：10.5603/fhc.2012.0039
更新日期：2012-07-05 00:00:00
abstract：:Diplotene oocyte nucleus of the scorpionfly Panorpa communis is transcriptionally silent and contains numerous nuclear bodies including interchromatin granule clusters (IGCs). The latter consist of the granules of 30-50 nm in diameter and contain IGC marker protein SC35 as well as RNA polymerase II. In this study, we ...
journal_title：Folia histochemica et cytobiologica
pub_type： 杂志文章
doi：10.2478/v10042-009-0006-2
更新日期：2009-01-01 00:00:00
abstract：:The aim of our study was to investigate the dynamics of the alterations of soluble human leukocyte antigen-G (sHLA-G) concentrations in sera of healthy non-pregnant women, as well as healthy pregnant women and patients with pre-eclampsia. Thirty five patients with pre-eclampsia, 52 healthy pregnant women, and 24 healt...
journal_title：Folia histochemica et cytobiologica
pub_type： 杂志文章
doi：10.5603/fhc.2012.0023
更新日期：2012-07-05 00:00:00
abstract：INTRODUCTION:Previous studies analyzing ghrelin and obestatin expression in thyroid gland tissue are not unanimous and are mostly related to ghrelin. The role of ghrelin and obestatin in the thyroid gland appears very interesting due to their probable involvement in cell proliferation. Furthermore, since the thyroid gl...
journal_title：Folia histochemica et cytobiologica
pub_type： 杂志文章
doi：10.5603/FHC.a2015.0004
更新日期：2015-01-01 00:00:00
abstract：INTRODUCTION:Overexpression of growth hormone (GH) leads to increase in insulin-like growth factor-1 (IGF-1) plasma level, stimulation of growth and increase in body size, organomegaly and reduced body fat. The action of GH affects all the organs and transgenic mice that overexpress bovine GH (bGH mice) serve as conven...
journal_title：Folia histochemica et cytobiologica
pub_type： 杂志文章
doi：10.5603/fhc.a2015.0024
更新日期：2015-01-01 00:00:00
abstract：:We report here about the purification of prion protein 27-30 (PrP 27-30) and scrapie-associated fibrils (SAF) from hamsters infected with the 263K strain of scrapie. Ultrastructural analysis of fractions from scrapie-infected brains revealed numerous fibrils measuring approximately 20 nm in diameter and 100-200 nm in ...
journal_title：Folia histochemica et cytobiologica
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：:Coccoids (Coccinea, Coccoidea, Coccomorpha, scale insects, scales) are a highly diverse group of ectoparasitic insects. They comprise 2 subgroups: primitive archaeococcoids (= Orthezioidea sensu Koteja) and advanced neococcoids (= Coccoidea sensu Koteja). The ovaries of coccoids consist of numerous short telotrophic-m...
journal_title：Folia histochemica et cytobiologica
pub_type： 杂志文章,评审
doi：
更新日期：1998-01-01 00:00:00
abstract：:The use of cancer vaccines based on dendritic cells (DC) presenting tumor antigens can be a promising tool in the treatment of leukemia. The functional characteristics of leukemia derived DC is still to be elucidated. CD40 promotes survival, proliferation and differentiation of normal B cells. CD40 triggering was used...
journal_title：Folia histochemica et cytobiologica
pub_type： 杂志文章
doi：
更新日期：2007-01-01 00:00:00
abstract：:The most important features that determine the vital role of bone include: a) a continuous supply of calcium, which is indispensible for every cell of the entire organism at all times, and b) the delivery of circulating blood cells and some adult stem cells to keep the body vigorous, ready for self-reparation, and con...
journal_title：Folia histochemica et cytobiologica
pub_type： 杂志文章,评审
doi：10.5603/fhc.2011.0079
更新日期：2011-01-01 00:00:00
