Abstract:
:Diplotene oocyte nucleus of the scorpionfly Panorpa communis is transcriptionally silent and contains numerous nuclear bodies including interchromatin granule clusters (IGCs). The latter consist of the granules of 30-50 nm in diameter and contain IGC marker protein SC35 as well as RNA polymerase II. In this study, we also localized in P. communis oocyte IGCs the transcription coactivators CBP/p300, TATA-binding protein (TBP) which is a component of the basal transcription factor TFIID and the basal transcription factor TFIIH. We belive that IGCs in transcriptionally inert P. communis oocytes are storage sites for the components of RNA polymerase II holoenzyme and other factors of RNA pol II transcription.
journal_name
Folia Histochem Cytobioljournal_title
Folia histochemica et cytobiologicaauthors
Batalova F,Parfenov Vdoi
10.2478/v10042-009-0006-2subject
Has Abstractpub_date
2009-01-01 00:00:00pages
123-6issue
1eissn
0239-8508issn
1897-5631pii
UTT534330403464Ujournal_volume
47pub_type
杂志文章abstract::Spermatogenesis involves the realization of a particular genetic program which requires a specific environment ("niche"). Multiplication, differentiation and apoptosis of male germ cells are finely regulated by pituitary hormones (mainly LH and FSH), and by a complex network of factors originating from both the somati...
journal_title:Folia histochemica et cytobiologica
pub_type: 杂志文章
doi:10.2478/v10042-009-0061-8
更新日期:2009-01-01 00:00:00
abstract::After dmPGE2 treatment, both alone or together with streptozotocin, the lower, statistically significant total PL contents (in mumoles P per mg of protein) in rat liver Golgi-rich membrane fractions were found. In these groups of investigated rats, the percentage of PE+PA were statistically significantly lower than in...
journal_title:Folia histochemica et cytobiologica
pub_type: 杂志文章
doi:
更新日期:1986-01-01 00:00:00
abstract::Within the thymus gland of the European common frog, Rana temporaria, cells with endocrine- like appearance have been found. At the ultrastructural level the most characteristic feature of their cytoplasm is the presence of secretory granules. Some cells possess irregular electron lucent granules with an eccentrically...
journal_title:Folia histochemica et cytobiologica
pub_type: 杂志文章
doi:
更新日期:1988-01-01 00:00:00
abstract:INTRODUCTION:Sucla2, a β subunit of succinyl coenzyme A synthase, is located in the mitochondrial matrix. Sucla2 catalyzes the reversible synthesis of succinate and adenosine triphosphate (ATP) in the tricarboxylic acid cycle. Sucla2 expression was found to be correlated with the capacitation of boar spermatozoa. We ha...
journal_title:Folia histochemica et cytobiologica
pub_type: 杂志文章
doi:10.5603/FHC.a2016.0020
更新日期:2016-01-01 00:00:00
abstract::Mice--BDF, hybrides, males aged 3 months were injected intraperitoneally with 10(4) lymphatic leukemia cells P 388. The mice were killed by bleeding after 2.5 and 10 days after the injection. Gamma-glutamyltransferase (GGT), leucylaminopeptidase (LAP) and cobalt activated acylase activity were determined in the serum ...
journal_title:Folia histochemica et cytobiologica
pub_type: 杂志文章
doi:
更新日期:1987-01-01 00:00:00
abstract::STAT3 upregulates expression of HIF-1 induced EPO. Receptor EPOR was reported to activate STAT3. Our study was aimed at demonstration of tissue immunoreactivities of those proteins and determination of their relationships in reference to clinicopathological variables of breast cancers. We detected STAT3, HIF-1alpha, E...
journal_title:Folia histochemica et cytobiologica
pub_type: 杂志文章
doi:
更新日期:2007-01-01 00:00:00
abstract::The frequency of Helicobacter pylori infection in population can depend on the organism resistance, genetic condition, and bacterial strains virulence. A vacA gene, of mosaic structure, which encodes vacuolating cytotoxin is one of the known genes of H. pylori. The existence of several different genotypes of s and m r...
journal_title:Folia histochemica et cytobiologica
pub_type: 杂志文章
doi:
更新日期:2007-01-01 00:00:00
abstract:INTRODUCTION:In traditional medicine, Citrullus colocynthis is used to treat diabetes, hyperlipidemia, cardiovascular diseases, inflammation, and oxidative stress, all of which can appear when a diet rich in vegetable fats, such as palm oil, is continuously consumed. Such high-fat diets are chronic stressors of the hyp...
journal_title:Folia histochemica et cytobiologica
pub_type: 杂志文章
doi:10.5603/FHC.a2017.0011
更新日期:2017-01-01 00:00:00
abstract::The aim of our study was to investigate the dynamics of the alterations of soluble human leukocyte antigen-G (sHLA-G) concentrations in sera of healthy non-pregnant women, as well as healthy pregnant women and patients with pre-eclampsia. Thirty five patients with pre-eclampsia, 52 healthy pregnant women, and 24 healt...
journal_title:Folia histochemica et cytobiologica
pub_type: 杂志文章
doi:10.5603/fhc.2012.0023
更新日期:2012-07-05 00:00:00
abstract::Structural chromosome aberrations and associated segmental or chromosomal aneusomies are major causes of reproductive failure in humans. Despite the fact that carriers of reciprocal balanced translocation often have no other clinical symptoms or disease, impaired chromosome homologue pairing in meiosis and karyokinesi...
journal_title:Folia histochemica et cytobiologica
pub_type: 杂志文章
doi:10.2478/v10042-009-0067-2
更新日期:2009-01-01 00:00:00
abstract::A literature survey was performed of human cathepsin D gene, cathepsin D biosynthesis, posttranslatory modifications, transport within the cell, substrate specificity and catalytic effect. Methods used to determine the activity and level of this proteinase as well as its role in the biochemistry and pathobiochemistry ...
journal_title:Folia histochemica et cytobiologica
pub_type: 杂志文章,评审
doi:10.2478/v10042-008-0003-x
更新日期:2008-01-01 00:00:00
abstract::The aim of this study was to assess the impact of laparoscopic gastric banding and laparoscopic sleeve gastrectomy on the concentration of ghrelin, insulin, glucose, triglycerides, total and HDL-cholesterol, as well as AST and ALT levels in plasma in patients with obesity. The research includes 200 patients operated u...
journal_title:Folia histochemica et cytobiologica
pub_type: 杂志文章
doi:10.5603/fhc.2012.0039
更新日期:2012-07-05 00:00:00
abstract::The goal of our study was to compare the skeletal muscle regeneration induced by two types of injury: either crushing, that causes muscle degeneration as a result of mechanical devastation of myofibers, or the injection of a cardiotoxin that is a myotoxic agent causing myolysis of myofibers leading to muscle degenerat...
journal_title:Folia histochemica et cytobiologica
pub_type: 杂志文章
doi:10.2478/18710
更新日期:2012-04-24 00:00:00
abstract::The aim of this study was to examine the prevalence and clinicopathological significance of KRAS point mutation in endometrial hyperplasia and carcinoma. We analysed KRAS in 11 cases of complex atypical hyperplasia and in 49 endometrial carcinomas using polymerase chain reaction associated with restriction fragment le...
journal_title:Folia histochemica et cytobiologica
pub_type: 杂志文章
doi:10.2478/v10042-009-0014-2
更新日期:2009-01-01 00:00:00
abstract:INTRODUCTION:Previous studies analyzing ghrelin and obestatin expression in thyroid gland tissue are not unanimous and are mostly related to ghrelin. The role of ghrelin and obestatin in the thyroid gland appears very interesting due to their probable involvement in cell proliferation. Furthermore, since the thyroid gl...
journal_title:Folia histochemica et cytobiologica
pub_type: 杂志文章
doi:10.5603/FHC.a2015.0004
更新日期:2015-01-01 00:00:00
abstract::At present, not much is known about progesterone receptor (PR) expression and localization in postmenopausal women ovaries. In the ovaries of reproductive age women, PR is localized in internal theca and granulosa cells, corpus luteum, ovary surface epithelium (OSE) and in stroma. PR expression depends on the serum co...
journal_title:Folia histochemica et cytobiologica
pub_type: 杂志文章
doi:10.2478/v10042-008-0038-z
更新日期:2008-01-01 00:00:00
abstract::Platinum-based chemotherapy is the main type of I-line treatment of advanced and non-operative NSCLC patients without EGFR gene mutation. The excision repair cross-complementation group 1 (ERCC1) is an enzyme that executes the incision of the damaged DNA strand and removes platinum-induced DNA adducts. We investigated...
journal_title:Folia histochemica et cytobiologica
pub_type: 杂志文章
doi:10.2478/18700
更新日期:2012-04-24 00:00:00
abstract::The aim of the study was to evaluate the influence of a nitric oxide donor: Glyco-2-SNAP on the proliferation status of two breast cancer cell lines: MDA-MB-231 and MCF-7. The study was performed by the thymidine incorporation method as well as by the immunocytochemical detection of the Ki-67 antigen. We found that th...
journal_title:Folia histochemica et cytobiologica
pub_type: 杂志文章
doi:
更新日期:2001-01-01 00:00:00
abstract::The biology of breast cancer is closely releted to sex steroid hormones. Estrogen receptor beta is overexpressed in around 70% breast cancer cases, referrd to as "ER positive". Estrogens bind to estrogen receptor and stimulate the transcription of genes involved in control of cell proliferation. Moreover, estrogens ma...
journal_title:Folia histochemica et cytobiologica
pub_type: 杂志文章
doi:10.2478/v10042-009-0047-6
更新日期:2009-01-01 00:00:00
abstract::The study was undertaken to determine the immunoexpression of protein products of nm23 genes which are thought to be potential metastasis suppressor genes, in esophageal squamous cell carcinoma, and to analyze their relationship to selected clinicopathological features (age, sex, tumour size, depth of invasion, presen...
journal_title:Folia histochemica et cytobiologica
pub_type: 杂志文章
doi:
更新日期:2002-01-01 00:00:00
abstract::In cervical cancer, glycosylation has been suggested as being involved in both its carcinogenesis and invasive capacity. In this work, we analyzed mucin type O-glycosylation in biopsies of invasive cervical cancer in FIGO stage II B through histochemistry using lectins specific for O-glycosidically linked glycans. Our...
journal_title:Folia histochemica et cytobiologica
pub_type: 杂志文章
doi:10.5603/19748
更新日期:2012-10-08 00:00:00
abstract:INTRODUCTION:Overexpression of growth hormone (GH) leads to increase in insulin-like growth factor-1 (IGF-1) plasma level, stimulation of growth and increase in body size, organomegaly and reduced body fat. The action of GH affects all the organs and transgenic mice that overexpress bovine GH (bGH mice) serve as conven...
journal_title:Folia histochemica et cytobiologica
pub_type: 杂志文章
doi:10.5603/fhc.a2015.0024
更新日期:2015-01-01 00:00:00
abstract::The relationship between alcohol consumption and glycoconjugate metabolism is complex and multidimensional. This review summarizes the advances in basic and clinical research on the molecular and cellular events involved in the metabolic effects of alcohol on glycoconjugates (glycoproteins, glycolipids, and proteoglyc...
journal_title:Folia histochemica et cytobiologica
pub_type: 杂志文章,评审
doi:10.2478/18690
更新日期:2012-04-24 00:00:00
abstract::The effect of limited amino acid nutrition upon the growth of B16 melanoma cells was investigated. It was observed that the cells in Basal Medium Eagle do not proliferate and are inhibited predominantly in the G1 phase of cell cycle. The cells which were inhibited in growth for 7 or 12 days in Basal Medium Eagle were ...
journal_title:Folia histochemica et cytobiologica
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract::Therapeutic outcomes of definitively treated non-small-cell lung cancer (NSCLC) are unacceptably poor. It has been proposed that the manipulation of dendritic cells (DCs) as a "natural" vaccine adjuvant may prove to be a particularly effective way to stimulate antitumor immunity. Presently, there is no standardized me...
journal_title:Folia histochemica et cytobiologica
pub_type: 杂志文章
doi:10.2478/v10042-008-0078-4
更新日期:2008-01-01 00:00:00
abstract::Twenty-four male volunteers (mean +/- SD: age 25.4+/-5.8 years, height 178.6+/-5.5 cm, body mass 72.1+/-7.7 kg) of different training background were investigated and classified into three groups according to their physical activity and sport discipline: untrained students (group A), national and sub-national level en...
journal_title:Folia histochemica et cytobiologica
pub_type: 杂志文章
doi:
更新日期:2004-01-01 00:00:00
abstract::A literature survey was performed of the methods of quantitative assessment of the activity and concentration of cathepsin D and its inhibitors. Usefulness of non-modified and modified proteins and synthetic peptides as measurement substrates was evaluated. The survey includes also chemical and immunochemical methods ...
journal_title:Folia histochemica et cytobiologica
pub_type: 杂志文章,评审
doi:10.2478/v10042-009-0073-4
更新日期:2009-01-01 00:00:00
abstract::Histochemical and immunohistochemical methods should often but not always complement standardized histopathologic procedures. Here, we illustrate use of these ancillary techniques in a report of scrotal leiomyosarcoma. 62-year-old male patient presented with a palpable, subcutaneous 2,5 cm wide tumor arising from dart...
journal_title:Folia histochemica et cytobiologica
pub_type: 杂志文章
doi:10.5603/FHC.2013.0046
更新日期:2013-01-01 00:00:00
abstract::The NADPH-diaphorase (NADPH-d) reaction is frequently used to visualize the diaphorase activity of nitric oxide synthase (NOS). However, this tetrazolium salt procedure can be of limited specificity at sites where non-specific alkaline phosphatase (alP) and NADHd activity co-exist. This is shown in the present paper u...
journal_title:Folia histochemica et cytobiologica
pub_type: 杂志文章
doi:
更新日期:1995-01-01 00:00:00
abstract::Coccoids (Coccinea, Coccoidea, Coccomorpha, scale insects, scales) are a highly diverse group of ectoparasitic insects. They comprise 2 subgroups: primitive archaeococcoids (= Orthezioidea sensu Koteja) and advanced neococcoids (= Coccoidea sensu Koteja). The ovaries of coccoids consist of numerous short telotrophic-m...
journal_title:Folia histochemica et cytobiologica
pub_type: 杂志文章,评审
doi:
更新日期:1998-01-01 00:00:00