Antimicrobial drug-selection markers for Burkholderia pseudomallei and B. mallei.

Abstract:

:Genetic research into the select agents Burkholderia pseudomallei and B. mallei is currently hampered by a paucity of approved antimicrobial drug-selection markers. The strict regulations imposed on researchers in the United States but not in other parts of the world lead to discrepancies in practice, hinder distribution of genetically modified strains, and impede progress in the field. Deliberation and decisions regarding alternative selection markers (antimicrobial and nonantimicrobial drugs) by the international community, regulatory authorities, and funding agencies are needed.

journal_name

Emerg Infect Dis

authors

Schweizer HP,Peacock SJ

doi

10.3201/eid1411.080431

subject

Has Abstract

pub_date

2008-11-01 00:00:00

pages

1689-92

issue

11

eissn

1080-6040

issn

1080-6059

journal_volume

14

pub_type

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