Abstract:
:A non-randomized comparative clinical trial of the progestin-only oral contraceptive (POC), Ovrette (75 mcg norgestrel) (Wyeth), versus non-hormonal methods was conducted at two clinics in Buenos Aires, Argentina. The trial was designed to assess the breast-feeding patterns of women choosing progestin-only oral contraception and non-hormonal methods of contraception, and to study the relationship between lactation and the clinical performance of a POC. Five-hundred women were allocated to either the progestin-only pill group (n = 250) or to the non-hormonal group (n = 250) and were followed up monthly for six months after admission. Measurements in mean infant weight, mean infant length, and mean head circumference were similar throughout the follow-up period. Non-hormonal users reported significantly more self-perceived decreases in milk production at the 5th and 6th month follow-up intervals. Acceptance and continued use of the pill were excellent, with only one woman discontinuing because of a pregnancy which was attributed to user failure. The principal side effect reported by women in both groups was intermenstrual bleeding. :A nonrandomized, comparative, clinical trial of the progestin only oral contraceptive (OC) Ovrette (75 mcg norgestrel) vs. nonhormonal methods was conducted at 2 clinics in Buenos Aires, Argentina. The trial was designed to assess breast-feeding patterns of women choosing progestin- only OCs and nonhormonal methods of contraception and to study the relationship between lactation and the clinical performance of the OC. 500 women were allocated to either the progestin-only pill group (n=250) or t o the nonhormonal group (n=250) and were followed monthly for 6 months after admission. Measurements in mean infant weight, mean infant length, and mean head circumference were similar throughout the follow- up period. Nonhormonal users reported significantly more self-perceived decreases in milk production at the 5th an 6th month follow-up intervals. Acceptance and continued use of the pill were excellent, with only 1 women discontinuing because of a pregnancy which was the result of user failure. The principal side effect reported by women in both groups was intermenstrual bleeding.
journal_name
Contraceptionjournal_title
Contraceptionauthors
Moggia AV,Harris GS,Dunson TR,Diaz R,Moggia MS,Ferrer MA,McMullen SLdoi
10.1016/0010-7824(91)90104-nsubject
Has Abstractpub_date
1991-07-01 00:00:00pages
31-43issue
1eissn
0010-7824issn
1879-0518pii
0010-7824(91)90104-Njournal_volume
44pub_type
临床试验,杂志文章相关文献
CONTRACEPTION文献大全abstract::The study reported herein is the primary efficacy and safety study conducted to support U.S. registration of an oral contraceptive containing 150 micrograms desogestrel and 30 micrograms ethinyl estradiol. A large multicenter study enrolled 1,221 women at 50 centers in the United Kingdom. A total of 11,656 cycles of e...
journal_title:Contraception
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1016/0010-7824(92)90094-a
更新日期:1992-10-01 00:00:00
abstract:OBJECTIVE:To investigate whether mental illness and substance use disorder (SUD) are associated with having a prescription contraceptive method among women veterans. STUDY DESIGN:We conducted a retrospective analysis of National Veterans Administration (VA) administrative and clinical data for women veterans aged 18-4...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/j.contraception.2014.02.028
更新日期:2014-07-01 00:00:00
abstract:OBJECTIVES:The risk of pregnancy is estimated to be 20 times as high among women who use oral contraception, and 90 times as high among condom users, as among women who use certain long-acting contraceptive methods. We explored the population-level implications of this variation in contraceptive efficacy. STUDY DESIGN...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/j.contraception.2016.03.014
更新日期:2016-08-01 00:00:00
abstract::Sexually transmitted infections and unplanned pregnancies present a great risk to the reproductive health of women. Therefore, female-controlled vaginal products directed toward disease prevention and contraception are needed urgently. In the present study, efforts were made to evaluate the contraceptive potential of ...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/j.contraception.2003.11.002
更新日期:2004-04-01 00:00:00
abstract::A single intratesticular injection of TEPA or Thio-TEPA induced a period of infertility lasting 1-2 months. Restoration of fertility was characterized by a reduction of the litter size resulting from the first inpregnation post-treatment. There was no evidence of tissue pathogenesis 6-12 months after treatment. ...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/0010-7824(80)90061-x
更新日期:1980-08-01 00:00:00
abstract::Intramuscular administration of STS 557 (17 alpha C-cyanomethyl-17 beta-hydroxy-estra-4,9(10)-diene-3-one) at a daily dose of 12 mg/monkey for 8 weeks induced severe oligospermia to complete azoospermia by the 9th week of initiation of treatment with concomitant decrease in the serum level of testosterone. The sperm m...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/0010-7824(88)90009-1
更新日期:1988-06-01 00:00:00
abstract:BACKGROUND:Highly effective contraception is essential in obese women, but it should not increase their risk of developing or worsening obesity-related cardiometabolic illness. The purpose of this 18-week prospective experimental study was to compare the impact of subcutaneous depot medroxyprogesterone acetate (DMPA-SC...
journal_title:Contraception
pub_type: 临床试验,杂志文章
doi:10.1016/j.contraception.2011.04.016
更新日期:2012-01-01 00:00:00
abstract::A study has been made of the serum 25-hydroxycholecalciferol (25-HCC) levels in six groups of women. Significant differences were found between the one pregnant group and the two reference groups as well as between the one pregnant group and two of the three groups using oral contraceptives. No significant differences...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/0010-7824(81)90029-9
更新日期:1981-04-01 00:00:00
abstract::The objectives of this study were to define the "normal" position of the T-shaped intrauterine device (IUD) in the endometrial cavity, using transvaginal ultrasound, and to compare the IUD's position in women with and without complaints of bleeding and/or pain. Vaginal ultrasound was carried out in women who had used ...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/s0010-7824(97)00072-3
更新日期:1997-07-01 00:00:00
abstract::Hsp70-2 functions as a molecular chaperone that assists other proteins in their folding, transport and assembly into complexes, and is postulated to be linked to the mechanisms that inhibit apoptosis. Here we have determined the association between Hsp70-2 gene and germ cell apoptosis induced by a high dose of testost...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/s0010-7824(02)00357-8
更新日期:2002-11-01 00:00:00
abstract:PURPOSE:The purpose of this study was to explore the relationship between oral contraceptive pill (OCP) use and the experience of depressive symptoms among a representative sample of young Australian women. METHODS:The study sample comes from the Australian Longitudinal Study on Women's Health. Analysis was confined t...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/j.contraception.2006.08.002
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVES:To evaluate the impact of a scholarly concentration for medical students, which aims to develop students' research, clinical and advocacy skills to promote women's reproductive health. STUDY DESIGN:Scholarly concentration programs provide opportunities to engage in scholarship beyond the traditional medical...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/j.contraception.2014.07.005
更新日期:2014-11-01 00:00:00
abstract::A study of the effect of a low-dose oral contraceptive, Adepal (ethinyl estradiol and levonorgestrel, 30 and 150 micrograms on the 5th to 12th, 40 and 200 micrograms on the 13th to 28th, respectively) on the blood lipids, lipoproteins and fatty acid composition has been conducted on 13 young women before and after six...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/0010-7824(83)90038-0
更新日期:1983-10-01 00:00:00
abstract::In a prospective, randomised dose-finding study involving 60 women scheduled for termination of 1st trimester pregnancy, 25 micrograms, 50 micrograms or 100 micrograms of a sulprostone gel with a constant injection volume of 2.5 ml were applied intracervically 6-8 hours before curettage. The gelatinising agent was Plu...
journal_title:Contraception
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0010-7824(85)90091-5
更新日期:1985-03-01 00:00:00
abstract::The effect of continuous release of microquantities of cyproterone acetate from subcutaneously implanted silastic capsules on the fertility of surgically manipulated seminal vesicles of rat has been studied. The experimental animals showed infertility for 3 weeks, as a consequence of removal of seminal plasma, followi...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/0010-7824(80)90130-4
更新日期:1980-02-01 00:00:00
abstract::The interceptive effect of the powder of Solanum lycocarpum (St. Hil) (Solanaceae) fruit, used as a hypoglycemic agent by diabetic patients in Minas Gerais state (Brazil), was evaluated to observe possible effects upon zygote and pre-embryo transport in rats, since it contains solamargine and solasonine from which a 3...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/s0010-7824(00)00188-8
更新日期:2001-01-01 00:00:00
abstract:OBJECTIVE:To develop a nurse-led model of medication abortion provision for the primary health care setting of regional and rural Victoria, where, despite decriminalization, access to abortion services is restricted. STUDY DESIGN:This study used a three-round Delphi process to explore consensus about a nurse-led medic...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/j.contraception.2019.07.004
更新日期:2019-11-01 00:00:00
abstract::In a cross-over study with orally administered desogestrel (0.150 mg) plus ethinyloestradiol (0.030 mg) and 3-keto-desogestrel (0.150 mg) plus ethinyloestradiol (0.030 mg) in ten women under steady-state conditions, the serum levels of 3-keto-desogestrel were monitored by radioimmunoassay. No statistically significant...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/0010-7824(86)90047-8
更新日期:1986-06-01 00:00:00
abstract:BACKGROUND:This study was conducted to compare breast epithelial-cell proliferation and estrogen and progesterone receptor levels in women taking one of two oral contraceptives (OCs) containing the same dose of estrogen but different doses of the progestin norethindrone (NET). STUDY DESIGN:Thirty-three women were rand...
journal_title:Contraception
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.contraception.2011.12.015
更新日期:2012-09-01 00:00:00
abstract:OBJECTIVES:Federally Qualified Health Centers (FQHCs) are a major and growing source of primary care for low-income women of reproductive age; however, only limited knowledge exists on the scope of family planning care they provide and the mechanisms for delivery of these essential reproductive health services, includi...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/j.contraception.2013.09.015
更新日期:2014-02-01 00:00:00
abstract:OBJECTIVES:To examine trends and utilization patterns of NYC abortion services by nonresidents since growing abortion restrictions across many states could drive women to seek care in less restrictive jurisdictions including NYC. STUDY DESIGN:We used data from Induced Termination of Pregnancy certificates filed with t...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/j.contraception.2019.05.008
更新日期:2019-09-01 00:00:00
abstract::Increased menstrual blood loss (MBL) associated with intrauterine device (IUD) use may precipitate or aggravate iron deficiency anaemia, adversely affecting the health of women particularly those from developing countries. Studies were conducted to define the association of MBL and iron status in South American women;...
journal_title:Contraception
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0010-7824(88)90091-1
更新日期:1988-07-01 00:00:00
abstract::In this open-label, randomized study we compared the influence of a new oral contraceptive containing 30 microg ethinylestradiol and 3 mg drospirenone (EE + DRSP = Yasmin), with a reference preparation containing 30 microg ethinylestradiol and 150 microg desogestrel (EE + DSG = Marvelon) on the lipid profile. The prim...
journal_title:Contraception
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/j.contraception.2003.11.003
更新日期:2004-04-01 00:00:00
abstract::This report provides specific information on the prevalence rates of the most common side effects during the first 3 cycles of use of 3 combination oral contraceptives (OCs) containing 50 mcg estrogen. The probabilities of a symptom occurring for the first time, or persisting once present, during the initial cycles of...
journal_title:Contraception
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0010-7824(79)90050-7
更新日期:1979-11-01 00:00:00
abstract::The effects of cyproterone acetate (CPA), administered orally in dos es of either 10 or 20 mg/day for 26 weeks, were studied in 15 healthy male volunteers. During treatment, there was a decrease in sperm density and in normal-shaped sperm and an increase in pathological and immature forms, an increase in dead spermat...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/0010-7824(76)90081-0
更新日期:1976-08-01 00:00:00
abstract::This study examines contraceptive delivery characteristics and their association with contraceptive behavior. Data were collected in telephone interviews from a national sample of 1057 women who were using female contraceptives. The overwhelming majority of the sample obtained contraceptive services from gynecologists...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/0010-7824(89)90074-7
更新日期:1989-12-01 00:00:00
abstract:OBJECTIVES:This study is designed to evaluate the popularity of vasectomy in Iran. The study was conducted to calculate the frequency of vasectomy over time, to compare vasectomy users' characteristics with the general population and whether these characteristics have changed over time. STUDY DESIGN:A cross-sectional ...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/j.contraception.2015.07.010
更新日期:2015-11-01 00:00:00
abstract:BACKGROUND:Obesity is becoming increasingly common in obstetric and gynecologic populations, which may affect the safety of surgical termination of pregnancy. STUDY DESIGN:We performed a retrospective review of all patients undergoing second-trimester surgical termination of pregnancy by under ultrasound guidance term...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/j.contraception.2012.02.006
更新日期:2012-10-01 00:00:00
abstract::A small survey to assess the perception and experience of current family planning users and their husbands was carried out in a university family planning clinic. Women routinely visiting the clinic were asked to complete a short Screening Form. Fifty-six women responded to the questionnaire concerning their attitude ...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/0010-7824(91)90118-y
更新日期:1991-08-01 00:00:00
abstract::The aim of this prospective study was the follow-up for 2 years in symptoms, serum prolactin (PRL) levels, and radiological aspects of a group of young patients using oral contraceptives (OC) with hyperprolactinemia. A total of 16 hyperprolactinemic women (eight with idiopathic hyperprolactinemia and eight with pituit...
journal_title:Contraception
pub_type: 临床试验,杂志文章
doi:10.1016/s0010-7824(98)00069-9
更新日期:1998-08-01 00:00:00