A customized genetic approach to the number one killer: coronary artery disease.

abstract：:Endocarditis remains a major worldwide problem despite significant advances in diagnostic and therapeutic interventions. This review centers on the recent studies that have been published in the past year concerning the epidemiologic, diagnostic, and therapeutic aspects of infective and noninfective endocarditis in bo...

journal_title：Current opinion in cardiology

authors： Farmer JA,Torre G

更新日期：1997-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Pediatric heart transplants continue to be the therapy of choice for children with end stage heart failure. The interplay of limited donor supply, improvement in ventricular assist device (VAD) technology and utilization, and a focus on optimizing long-term outcomes make it critically important for pr...

journal_title：Current opinion in cardiology

authors： Zangwill S

更新日期：2017-01-01 00:00:00

abstract：:There has been an intensive effort in the past year to identify immunologic and nonimmunologic factors in the pathogenesis of cardiac allograft vasculopathy. Significant progress has been made regarding cell proliferation and cell death, with particular focus on cell growth factors, cell death factors, and their recep...

journal_title：Current opinion in cardiology

authors： Dong C,Redenbach D,Wood S,Battistini B,Wilson JE,McManus BM

更新日期：1996-03-01 00:00:00

abstract：:For more than three decades, conventional coronary artery bypass grafting (full sternotomy, cardiopulmonary bypass, and cardioplegic arrest) has been the treatment of choice for patients with multi-vessel coronary artery disease. However, neurologic injury secondary to ascending aortic manipulation and systemic inflam...

journal_title：Current opinion in cardiology

authors： Filsoufi F,Aklog L,Adams DH

更新日期：2001-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Advanced heart failure is a chronic, systemic disease, which affects other organs in ways that are incompletely understood. Patients with advanced heart failure commonly develop congestive hepatopathy, which may lead to progressive hepatic injury and fibrosis. Because the independent adverse effects o...

journal_title：Current opinion in cardiology

authors： Maltais S,Stulak JM

更新日期：2016-05-01 00:00:00

abstract：:Cardiopulmonary bypass triggers a generalized inflammatory response that is largely mediated by activation of polymorphonuclear neutrophils, their adhesion to endothelial cells, and the subsequent release of cytotoxic products. It has been known for several years that the inflammatory response to extracorporeal circul...

journal_title：Current opinion in cardiology

authors： Menasché P

更新日期：1995-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Patients with multivessel coronary artery disease (CAD) may undergo revascularization by either percutaneous coronary intervention (PCI) or coronary artery bypass graft surgery (CABG). This review will discuss the use of polygenic risk scores for risk-stratification of patients with multivessel CAD in...

journal_title：Current opinion in cardiology

authors： Hui SK,Lindale E,Sun L,Ruel M

更新日期：2018-11-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this review is to update the cardiovascular clinician on the current status of surgical therapies aimed at achieving reverse ventricular remodeling. RECENT FINDINGS:Relevant research focusing on mechanical options for reverse ventricular remodeling will be referenced and summarized. SUMMA...

journal_title：Current opinion in cardiology

authors： McGee EC,Gillinov AM,McCarthy PM

更新日期：2006-05-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this article is to review the strengths and weaknesses of systematic reviews and meta-analyses to inform our current understanding of cardiac surgery. RECENT FINDINGS:A systematic review and meta-analysis of a focused topic can provide a quantitative estimate for the effect of a treatm...

journal_title：Current opinion in cardiology

authors： Yanagawa B,Tam DY,Mazine A,Tricco AC

更新日期：2018-03-01 00:00:00

abstract：:Acute mesenteric ischemia (AMI) remains a complex and difficult clinical problem. Such acute ischemia is usually either embolic or thrombotic in nature, but other etiologies exist. The diagnosis of AMI is difficult to establish and often delayed, resulting in irreversible bowel injury that requires intestinal resectio...

journal_title：Current opinion in cardiology

authors： Vicente DC,Kazmers A

更新日期：1999-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Pulmonary hypertension is a progressive disease of the pulmonary vasculature characterized by increased vascular resistance and pressure overload of the right ventricle. This review aims to describe the diagnostic and prognostic role of echocardiography in pulmonary hypertension with particular consid...

journal_title：Current opinion in cardiology

authors： Bossone E,Ferrara F,Grünig E

更新日期：2015-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Coronary artery disease is common in patients with end-stage renal disease (ESRD) on hemodialysis. ESRD patients are prone to atherosclerosis and are likely to present with advanced CAD requiring coronary artery bypass graft surgery (CABG) or percutaneous coronary intervention (PCI). RECENT FINDINGS:...

journal_title：Current opinion in cardiology

authors： Karkhanis R,Tam DY,Fremes SE

更新日期：2018-09-01 00:00:00

abstract：:Recurrent episodes of unexplained syncope are among the most frequent of complaints referred to physicians for evaluation. Traditional methods of evaluation were both time consuming and expensive and left many patients without a diagnosis. Although neurocardiogenically mediated episodes of hypotension and bradycardia ...

journal_title：Current opinion in cardiology

authors： Grubb BP,Kosinski D

更新日期：1996-01-01 00:00:00

abstract：:Optimized medical treatment for the non-ST segment elevation acute coronary syndromes (NSTE ACS) should consist of a combined antithrombotic/anti-anginal regimen. Standard antithrombotic treatment is currently unfractionated heparin and aspirin, and in high-risk patients glycoprotein IIb/IIIa inhibitors. However, low-...

journal_title：Current opinion in cardiology

authors： Cohen M

更新日期：2001-11-01 00:00:00

abstract：PURPOSE OF REVIEW:The health benefits of physical activity and exercise are clear; virtually everyone can benefit from becoming more physically active. Most international guidelines recommend a goal of 150 min/week of moderate-to-vigorous intensity physical activity. Many agencies have translated these recommendations ...

journal_title：Current opinion in cardiology

authors： Warburton DER,Bredin SSD

更新日期：2017-09-01 00:00:00

abstract：:Over the past year, significant new advances have been made in preventive cardiology. New trials of lipid lowering, estrogen therapy, and hypertension control have added to our understanding of the pathophysiology and prevention of coronary atherosclerosis. This review highlights these new trials and provides insight ...

journal_title：Current opinion in cardiology

authors： Foody JA

更新日期：1999-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Atrial fibrillation is an important cause of morbidity in the aging population. The mechanisms responsible for the triggering and maintenance of the chaotic atrial rhythm are still poorly understood. In this review, we will focus on the genetic aspects of atrial fibrillation, to understand causality, ...

journal_title：Current opinion in cardiology

authors： Pérez-Serra A,Campuzano O,Brugada R

更新日期：2017-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Ticagrelor is a new, direct acting, reversibly binding P2Y12 receptor antagonist with more potent inhibition of platelets than clopidogrel and which does not require metabolic activation. It was compared with clopidogrel, on a background of the standard of care in a randomized trial in the Platelet In...

journal_title：Current opinion in cardiology

authors： Held C

更新日期：2012-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Hypertension and dyslipidemia frequently coexist, and endothelial dysfunction is associated with the pathophysiology of both atherosclerosis and hypertension. Evidence is convincing for an overlapping role of oxidative stress, renin-angiotensin system activation, and dyslipidemia in the genesis of end...

journal_title：Current opinion in cardiology

authors： Sarkar K,Sinha AK,Mehta JL

更新日期：2006-07-01 00:00:00

abstract：PURPOSE OF REVIEW:To discuss the current evidence regarding the relationship between omega-3 fatty acid intake and atherosclerotic cardiovascular disease (ASCVD) risk. RECENT FINDINGS:Combined results from randomized controlled trials using low-dosage (≤1.8 g/day of ethyl esters) eicosapentaenoic acid (EPA) or EPA + d...

journal_title：Current opinion in cardiology

authors： Maki KC,Dicklin MR

更新日期：2020-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Diagnostic testing using noninvasive imaging has become an integral part of risk stratification in patients with coronary artery disease. It is important to understand the integral strengths and weaknesses between the different modalities of stress testing and to apply accurately the type of test the ...

journal_title：Current opinion in cardiology

authors： Maganti K,Rigolin VH

更新日期：2003-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Coronary subclavian steal syndrome (CSSS) is the reversal of blood flow in an internal mammary artery bypass graft that results in coronary ischemia. CSSS is an uncommon but treatable cause of coronary ischemia. In this review, we highlight the historical background and epidemiology of CSSS, common cl...

journal_title：Current opinion in cardiology

authors： Sintek M,Coverstone E,Singh J

更新日期：2014-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Heart failure and diabetes mellitus are frequently associated, and diabetes appears to potentiate the clinical presentation of heart failure related to other causes. The purpose of this review is to examine recent advances in the application of tissue Doppler imaging for the assessment of diabetic hea...

journal_title：Current opinion in cardiology

authors： Marwick TH

更新日期：2004-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The number of clinically available genetic tests for heritable cardiovascular diseases has recently increased because of novel gene discoveries and advancements in DNA sequencing technologies. The purpose of this review is to provide up-to-date genetic testing information and guidance on how to incorp...

journal_title：Current opinion in cardiology

authors： Sturm AC,Hershberger RE

更新日期：2013-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Non-invasive testing is often the first step in the evaluation of stable coronary artery disease (CAD). Stress cardiac magnetic resonance imaging (CMR) is an established modality with high diagnostic accuracy and prognostic value. This review will focus on the recent advances in understanding how stre...

journal_title：Current opinion in cardiology

authors： Ge Y,Deva DP,Connelly KA,Yan AT

更新日期：2020-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Atrial fibrillation after cardiac surgery is associated with adverse outcomes and increased costs. Accordingly, therapy should be provided to prevent postoperative atrial fibrillation. The evaluation of therapies to do so is an area of active investigation with significant recent advances. The purpose...

journal_title：Current opinion in cardiology

authors： Mitchell LB

更新日期：2007-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Device therapy for atrial fibrillation remains contentious despite the recognized benefit of atrial pacing in sinus node dysfunction. There are various new specialized pacing algorithms that aim to provide rhythm or rate control in atrial fibrillation. We review the various options for device therapy ...

journal_title：Current opinion in cardiology

authors： Redfearn DP,Yee R

更新日期：2006-03-01 00:00:00

abstract：:A trend toward use of less invasive, nonsurgical approaches to the treatment of congenital heart disease has developed. Although transcatheter valve replacements and ventricular septal defect closures have already been performed in children, many other techniques and devices are being developed for the palliation of c...

journal_title：Current opinion in cardiology

authors： Levi DS,Alejos JC,Moore JW

更新日期：2003-03-01 00:00:00

abstract：PURPOSE OF REVIEW:To summarize literature on the application of myocardial strain in patients with heart failure published since 2018. RECENT FINDINGS:Left ventricular (LV) and right ventricular strain provides important prognostic information in patients with acute and chronic heart failure and new insights in diseas...

journal_title：Current opinion in cardiology

authors： Edvardsen T,Klaeboe LG

更新日期：2019-09-01 00:00:00

abstract：:With 550,000 new cases each year, congestive heart failure is a major medical problem. Several medical therapies, including digoxin, angiotensin-converting enzyme inhibitors, and beta-blockers, have reduced the number of re-hospitalizations and slowed the progression of congestive heart failure. Angiotensin-converting...

journal_title：Current opinion in cardiology

authors： Luck JC,Wolbrette DL,Boehmer JP,Ulsh PJ,Silber D,Naccarelli GV

更新日期：2002-01-01 00:00:00