Abstract:
OBJECTIVE:To identify risk factors for surgical site infection (SSI) due to methicillin-resistant Staphylococcus aureus (MRSA). DESIGN:Prospective case-control study. SETTING:One tertiary and 6 community-based institutions in the southeastern United States. METHODS:We compared patients with SSI due to MRSA with 2 control groups: matched uninfected surgical patients and patients with SSI due to methicillin-susceptible S. aureus (MSSA). Multivariable logistic regression was used to determine variables independently associated with SSI due to MRSA, compared with each control group. RESULTS:During the 5-year study period, 150 case patients with SSI due to MRSA were identified and compared with 231 matched uninfected control patients and 128 control patients with SSI due to MSSA. Two variables were independently associated with SSI due to MRSA in both multivariable regression models: need for assistance with 3 or more activities of daily living (odds ratio [OR] compared with uninfected patients, 3.97 [95% confidence interval {CI}, 2.18-7.25]; OR compared with patients with SSI due to MSSA, 3.88 [95% CI, 1.91-7.87]) and prolonged duration of surgery (OR compared with uninfected patients, 1.98 [95% CI, 1.11-3.55]; OR compared with patients with SSI due to MSSA, 2.33 [95% CI, 1.17-4.62]). Lack of independence (ie, poor functional status) remained associated with an increased risk of SSI due to MRSA after stratifying by age. CONCLUSIONS:Poor functional status was highly associated with SSI due to MRSA in adult surgical patients, regardless of age. A patient's level of independence can be easily determined, and this information can be used preoperatively to target preventive interventions.
journal_name
Infect Control Hosp Epidemioljournal_title
Infection control and hospital epidemiologyauthors
Anderson DJ,Chen LF,Schmader KE,Sexton DJ,Choi Y,Link K,Sloane R,Kaye KSdoi
10.1086/590124subject
Has Abstractpub_date
2008-09-01 00:00:00pages
832-9issue
9eissn
0899-823Xissn
1559-6834journal_volume
29pub_type
杂志文章abstract:OBJECTIVE:Viruses are more common than bacteria in patients hospitalized with community-acquired pneumonia. Little is known, however, about the frequency of respiratory viral testing and its associations with antimicrobial utilization. DESIGN:Retrospective cohort study. SETTING:The study included 179 US hospitals. P...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2020.1312
更新日期:2020-12-01 00:00:00
abstract::Vancomycin is a commonly prescribed empiric antibiotic used when methicillin-resistant Staphylococcus aureus (MRSA) infection is suspected. In this study, we aimed to determine the rate of culture-positive infection requiring vancomycin therapy. ...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2018.123
更新日期:2018-08-01 00:00:00
abstract:OBJECTIVE:Evaluate aerobiological monitoring for fungal spores during hospital construction and correlate results with an outbreak of invasive aspergillosis (IA). DESIGN:Prospective air sampling for molds was done using the gravity air-settling plate (GASP) method. SETTING:A university medical center special care uni...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/646916
更新日期:1994-05-01 00:00:00
abstract::BACKGROUND The National Healthcare Safety Network (NHSN) catheter-associated urinary tract infection (CAUTI) definition was revised as of January 2015 to exclude funguria and lower bacteriuria levels. We evaluated the effect of the CAUTI definition change on NHSN-defined central-line-associated bloodstream infection (...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2017.41
更新日期:2017-06-01 00:00:00
abstract::A before-after-before direct comparison between catheters lined with chlorhexidine and silver sulfadiazine (CHSS) versus silver ionotrophes (SI) with a primary objective of comparison of rate of central-line-associated infection (CLABSI) in three 10-month windows. The CHSS catheters were associated with a lower rate o...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2020.423
更新日期:2020-09-11 00:00:00
abstract::We employed a questionnaire to survey 334 registered nurses regarding their knowledge, perceptions and vaccine acceptance for Hepatitis B virus (HBV) infections. The study population was those persons working in areas considered at high-risk for contracting HBV. The nurses were asked to provide information regarding b...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/646135
更新日期:1990-03-01 00:00:00
abstract::We investigated 4 hepatitis C virus (HCV) infection outbreaks at hemodialysis units to identify practices associated with transmission. Apparent failures to follow recommended infection control precautions resulted in patient-to-patient HCV transmission, through cross-contamination of the environment or intravenous me...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/605472
更新日期:2009-09-01 00:00:00
abstract::We report nosocomial infection with Vibrio cholerae 01, in four seriously ill individuals and one infant in Guatemala. Nosocomial cholera occurs in developing countries in Latin America and should be suspected in hospitalized patients with diarrhea, especially during community outbreaks, in order to institute appropri...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/647321
更新日期:1996-06-01 00:00:00
abstract::In implementing a hospital mandatory influenza vaccination policy, we developed an automated, real-time tracking and reminder system. Of 6,957 policy-covered individuals automatically identified, automated reminders left only 5 requiring counseling. This decreased Occupational Health workload in contacting noncomplian...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/678415
更新日期:2014-11-01 00:00:00
abstract:OBJECTIVE:In colorectal surgery, the composition of the most effective bundle for prevention of surgical site infections (SSI) remains uncertain. We performed a meta-analysis to identify bundle interventions most associated with SSI reduction. METHODS:We systematically reviewed 4 databases for studies that assessed bu...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2020.112
更新日期:2020-07-01 00:00:00
abstract:OBJECTIVE:Skin preparation is an important factor in reducing the rate of blood culture contamination. We assessed blood culture contamination rates associated with the use of skin antisepsis kits containing either 2% alcoholic chlorhexidine gluconate or 2% alcoholic tincture of iodine. DESIGN:Prospective, blinded cli...
journal_title:Infection control and hospital epidemiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1086/502073
更新日期:2002-07-01 00:00:00
abstract::We describe and compare the epidemiology of catheter-associated urinary tract infection (CAUTI) occurring in non-intensive care unit (ICU) versus ICU wards in a network of community hospitals over a 2-year period. Overall, 72% of cases of CAUTI occurred in non-ICU patients, which indicates that this population is an i...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/671000
更新日期:2013-07-01 00:00:00
abstract:OBJECTIVE:To develop an automated method for ventilator-associated condition (VAC) surveillance and to compare its accuracy and efficiency with manual VAC surveillance SETTING:The intensive care units (ICUs) of 4 hospitals METHODS:This study was conducted at Detroit Medical Center, a tertiary care center in metropoli...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2015.127
更新日期:2015-09-01 00:00:00
abstract::Surveillance for methicillin-resistant Staphylococcus aureus (MRSA) was implemented in Rio de Janeiro and Uberlândia University Hospitals, which had different policies on use of mupirocin. One hundred fourteen multiresistant MRSA strains were isolated from 62 patients. Mupirocin resistance was observed in 63% of strai...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:
更新日期:1996-12-01 00:00:00
abstract:OBJECTIVE:The effectiveness of hand-cleansing agents in removing a hospital strain of methicillin-resistant Staphylococcus aureus from artificially contaminated hands of five volunteers was studied. DESIGN:The products used were plain liquid soap, ethyl alcohol 70% (by weight), 10% povidone-iodine liquid soap (PVP-I),...
journal_title:Infection control and hospital epidemiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1086/501872
更新日期:2001-02-01 00:00:00
abstract::We evaluated the impact of reflex urine culture screen results on antibiotic initiation. More patients with positive urine screen but negative culture received antibiotics than those with a negative screen (30.5 vs 7.1%). Urine screen results may inappropriately influence antibiotic initiation in patients with a low l...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2020.230
更新日期:2020-09-01 00:00:00
abstract:OBJECTIVE:To study the spread of strains of Enterobacter aerogenes in our hospital in 1992 and 1993 by using two genotypic markers, and to evaluate these methods for the epidemiological investigation of this species. DESIGN:Ribotyping (using two endonucleases) and arbitrarily primed (AP)-PCR (using two different 10-me...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/647094
更新日期:1995-04-01 00:00:00
abstract:OBJECTIVE:Reduce the frequency of contaminated blood cultures that meet National Healthcare Safety Network definitions for a central line-associated bloodstream infection (CLABSI). DESIGN:An observational study. SETTING:A 500-bed university-affiliated hospital. METHODS:A new blood culture policy discouraged drawing ...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/673142
更新日期:2013-10-01 00:00:00
abstract:OBJECTIVES:To determine the rates of surgical-site infections (SSIs) after spinal surgery and to identify the risk factors associated with infection. DESIGN:SSIs had been identified by active prospective surveillance. A case-control study to identify risk factors was performed retrospectively. SETTING:University-asso...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/502259
更新日期:2003-08-01 00:00:00
abstract:OBJECTIVE:The National Nosocomial Infections Surveillance (NNIS) System personnel report trends in antimicrobial-resistant pathogens. To validate select antimicrobial susceptibility testing results and to identify test methods that tend to produce errors, we conducted proficiency testing among NNIS System hospital labo...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/502214
更新日期:2003-05-01 00:00:00
abstract::A patient with no risk factors for malaria was hospitalized in New York City with Plasmodium falciparum infection. After investigating all potential sources of infection, we concluded the patient had been exposed to malaria while hospitalized less than 3 weeks earlier. Molecular genotyping implicated patient-to-patien...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2015.236
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVE:To evaluate the efficacy of a standardized regimen for decolonization of methicillin-resistant Staphylococcus aureus (MRSA) carriers and to identify factors influencing decolonization treatment failure. DESIGN:Prospective cohort study from January 2002 to April 2007, with a mean follow-up period of 36 months...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/588201
更新日期:2008-06-01 00:00:00
abstract::We investigated a cluster of methicillin-resistant Staphylococcus aureus infections in college football players. Risk factors included a history of recurrent skin infections and contact with the skin lesions of persons outside college. The infections were controlled through treatment of carriers with topical mupirocin...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/587971
更新日期:2008-05-01 00:00:00
abstract::More than 90% of Thai hospitals surveyed reported implementing environmental cleaning and disinfection (ECD) protocols. Hospital epidemiologist presence was associated with the existence of an ECD checklist (P=.01) and of ECD auditing (P=.001), while good and excellent hospital administrative support were associated w...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2017.171
更新日期:2017-10-01 00:00:00
abstract:OBJECTIVE:To assess the diagnostic value of an adenosinetriphosphate bioluminescence assay (ATPmetry) to monitor the effectiveness of the reprocessing of endoscopes compared with microbiologic sampling. DESIGN:Diagnostic study. SETTING:A 2,200-bed teaching hospital performing 5,000 to 6,000 endoscopic procedures annu...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2015.212
更新日期:2015-12-01 00:00:00
abstract:OBJECTIVE:To evaluate the effectiveness of a positive deviance strategy for the improvement of hand hygiene compliance in 2 adult step-down units. DESIGN:A 9-month, controlled trial comparing the effect of positive deviance on compliance with hand hygiene. SETTING:Two 20-bed step-down units at a tertiary care private...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/649224
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVE:To determine the extent to which evidence-based practices for the prevention of central venous catheter (CVC)-associated bloodstream infections are incorporated into the policies and practices of academic intensive care units (ICUs) in the United States and to determine variations in the policies on CVC inser...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章,多中心研究
doi:10.1086/499151
更新日期:2006-01-01 00:00:00
abstract:OBJECTIVE:To determine whether disinfection protocols currently used for gastroscopes are effective against cultures of Tropheryma whipplei. DESIGN:The bactericidal activity of 2% glutaraldehyde and two peracetic acids on the Twist-Marseille strain of T. whipplei grown in cell monolayers was determined. PATIENTS:Two ...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/502188
更新日期:2003-03-01 00:00:00
abstract::OBJECTIVE Contaminated hands of healthcare workers (HCWs) are an important source of transmission of healthcare-associated infections. Alcohol-based hand sanitizers, while effective, do not provide sustained antimicrobial activity. The objective of this study was to compare the immediate and persistent activity of 2 h...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章,随机对照试验
doi:10.1017/ice.2017.293
更新日期:2018-03-01 00:00:00
abstract::BACKGROUND Healthcare provider hands are an important source of intraoperative bacterial transmission events associated with postoperative infection development. OBJECTIVE To explore the efficacy of a novel hand hygiene improvement system leveraging provider proximity and individual and group performance feedback in r...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章,随机对照试验
doi:10.1017/ice.2016.106
更新日期:2016-08-01 00:00:00