Abstract:
OBJECTIVE:Evaluate aerobiological monitoring for fungal spores during hospital construction and correlate results with an outbreak of invasive aspergillosis (IA). DESIGN:Prospective air sampling for molds was done using the gravity air-settling plate (GASP) method. SETTING:A university medical center special care unit consisting of single-patient rooms with high-efficiency particulate air filtration under positive pressure. PATIENTS:Five neutropenic patients who subsequently developed IA. RESULTS:Four of the five patients with IA were housed in rooms adjacent to a construction staging area. Aerobiological monitoring detected an increase in the number of airborne fungal spores including Aspergillus species in these rooms; however, increased counts preceded IA diagnosis by 1 to 7 days in only three of the five patients. Swab cultures of the exhaust vents within each room confirmed results from air-settling plates. Follow-up monitoring, using the GASP method, demonstrated that control procedures were effective in reducing air mold contamination. CONCLUSION:The GASP method, although able to demonstrate that infection control measures reduced mold contamination of the air, was insensitive to detect levels of mold contaminates in time to prevent IA.
journal_name
Infect Control Hosp Epidemioljournal_title
Infection control and hospital epidemiologyauthors
Iwen PC,Davis JC,Reed EC,Winfield BA,Hinrichs SHdoi
10.1086/646916subject
Has Abstractpub_date
1994-05-01 00:00:00pages
303-6issue
5eissn
0899-823Xissn
1559-6834journal_volume
15pub_type
杂志文章abstract:OBJECTIVES:To quantify specific factors believed to increase healthcare worker (HCW) risk for contaminated sharps injuries (eg, visibility, communication, and range of motion); to quantify the degree to which respirators of various designs impacted those same factors; and to assess HCW opinions about the suitability of...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/647566
更新日期:1997-02-01 00:00:00
abstract:OBJECTIVE:Multidrug-resistant Enterobacteriaceae pose a serious infection control challenge and have emerged as a public health threat. We examined national trends in the proportion of Klebsiella pneumoniae isolates resistant to carbapenems (CRKP) and third-generation cephalosporins (G3CRKP). DESIGN AND SETTING:Retros...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/669523
更新日期:2013-03-01 00:00:00
abstract:OBJECTIVE:To evaluate the efficacy of a multifaceted hospitalwide quality improvement program that featured an intervention to remind physicians to remove unnecessary urinary catheters. METHODS:A hospitalwide preintervention-postintervention study was conducted over 2 years (July 1, 2004, through June 30, 2006). The i...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/518453
更新日期:2007-07-01 00:00:00
abstract::Water samples taken from extracorporeal membrane oxygenator (ECMO) devices used at University Hospitals Birmingham yielded high total viable counts (TVCs) containing a variety of microorganisms, including M. chimaera. Disinfection resulted in the reduction of TVCs and eradication of Mycobacterium chimaera. Weekly disi...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2017.163
更新日期:2017-10-01 00:00:00
abstract:OBJECTIVE:To evaluate the impact of postdischarge surveillance on surgical site infection (SSI) rates after orthopedic surgery. SETTING:Nine hospitals participating in the Finnish Hospital Infection Program. PATIENTS:All patients who underwent hip or knee arthroplasty or open reduction of a femur fracture during 1999...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/509840
更新日期:2006-12-01 00:00:00
abstract::Infection control in British nursing homes is different from that in U.S. nursing homes in seveal ways. Most British nursing homes, for example, do not have a designated on-site infection control nurse, and several agencies are responsible for regulatory oversight. This article discusses the state of infection control...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/502198
更新日期:2003-04-01 00:00:00
abstract:OBJECTIVE:To evaluate the impact of changes to urine testing orderables in computerized physician order entry (CPOE) system on urine culturing practices. DESIGN:Retrospective before-and-after study. SETTING:A 1,250-bed academic tertiary-care referral center. PATIENTS:Hospitalized adults who had ≥1 urine culture perf...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2018.356
更新日期:2019-03-01 00:00:00
abstract::Because the severe acute respiratory syndrome (SARS) outbreak in Taiwan in 2003 was worsened by hospital infections, we analyzed 229 questionnaires (84.8% of 270 sent) completed by surveyed healthcare workers who cared for patients with SARS in 3 types of hospitals, to identify surveillance problems. Atypical clinical...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/508835
更新日期:2007-03-01 00:00:00
abstract::We describe characteristics of elderly patients with MRSA identified in 37 Canadian hospitals between 1995 and 2002. Of these inpatients, 6,613 (66%) were older than 65 years. They were more likely than younger patients to have been colonized without infection and to have had MRSA isolated from urine or the perineum. ...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章,多中心研究
doi:10.1086/502503
更新日期:2005-10-01 00:00:00
abstract::Malassezia furfur, a lipophilic yeast, has become recognized as a cause of sepsis in infants receiving parenteral fat emulsions via indwelling deep venous catheters. Colonization of infants' skin may be a prerequisite to colonization of the intravascular catheter and subsequent infection with M furfur. Three hundred n...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/645819
更新日期:1988-04-01 00:00:00
abstract:OBJECTIVE:The National Nosocomial Infections Surveillance (NNIS) System personnel report trends in antimicrobial-resistant pathogens. To validate select antimicrobial susceptibility testing results and to identify test methods that tend to produce errors, we conducted proficiency testing among NNIS System hospital labo...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/502214
更新日期:2003-05-01 00:00:00
abstract:OBJECTIVE:To determine whether disinfection protocols currently used for gastroscopes are effective against cultures of Tropheryma whipplei. DESIGN:The bactericidal activity of 2% glutaraldehyde and two peracetic acids on the Twist-Marseille strain of T. whipplei grown in cell monolayers was determined. PATIENTS:Two ...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/502188
更新日期:2003-03-01 00:00:00
abstract::OBJECTIVE Recerntly, the role of the healthcare network, defined as a set of hospitals linked by patient transfers, has been increasingly considered in the control of antimicrobial resistance. Here, we investigate the potential impact of nursing homes on the spread of antimicrobial-resistant pathogens across the healt...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2016.59
更新日期:2016-07-01 00:00:00
abstract:OBJECTIVE:To determine whether the molecular epidemiological characteristics of methicillin-resistant Staphylococcus aureus (MRSA) had changed in a level III neonatal intensive care unit (NICU). DESIGN:Retrospective review of medical records. SETTING:Level III NICU of a university-affiliated children's hospital in Ne...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/652526
更新日期:2010-06-01 00:00:00
abstract::Healthcare-associated infection reporting validation is essential because this information is increasingly used in public healthcare quality assurances and care reimbursement. Washington State's validation of central line-associated bloodstream infection reporting applies credible quality sciences methods to ensure th...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2016.303
更新日期:2017-04-01 00:00:00
abstract:BACKGROUND:Carbapenem-resistant Enterobacteriaceae (CRE) are rapidly emerging worldwide. Control group selection is critically important when analyzing predictors of antimicrobial resistance. Focusing on modifiable risk factors can optimize prevention and resource expenditures. To identify specific predictors of CRE, p...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/666642
更新日期:2012-08-01 00:00:00
abstract:OBJECTIVE:To describe an outbreak of imipenem-resistant Acinetobacter baumannii (IR-Ab) and the measures for its control, and to investigate risk factors for IR-Ab acquisition. DESIGN:An observational and a case-control study. SETTING:A surgical intensive care unit (ICU) in a university tertiary care hospital. METHO...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/501822
更新日期:2001-01-01 00:00:00
abstract:OBJECTIVE:To evaluate changing Clostridioides difficile infection (CDI) testing among inpatients with indeterminate enzyme immunoassay (EIA) results (antigen+/toxin-) from reflexive polymerase chain reaction (PCR) testing to clinician-ordered PCR testing. DESIGN:Multicenter, before-and-after, quasi-experimental study....
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2020.56
更新日期:2020-06-01 00:00:00
abstract::Over a 1-week period, Neisseria meningitidis serogroup B was recovered from two patients in the intensive-care unit (ICU). A cross-infection was presumed when one patient developed invasive meningococcal disease and another patient was found to be colonized. Investigation by molecular typing showed that these cases we...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/647589
更新日期:1997-03-01 00:00:00
abstract::We assessed hand hygiene adherence in 2 infectious disease units. In one unit, adherence declined slightly from year 1 (84.2%) to year 4 (71.0%) after a multimodal intervention but remained much higher than before intervention. Adherence dropped in the second unit after a loss of leadership (from 50.7% to 5.7%). Stron...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/675296
更新日期:2014-03-01 00:00:00
abstract:OBJECTIVE:To identify variables contributing to interfacility differences in mortality among residents of long-term care facilities who have lower respiratory tract infection. DESIGN:Multicenter, prospective, 1-year observational study. SETTING:Twenty-one long-term care facilities in 4 geographic areas of Canada. PA...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章,多中心研究
doi:10.1086/590123
更新日期:2008-08-01 00:00:00
abstract:OBJECTIVE:To establish a new, rapid, and reliable genotypic fingerprinting technique for methicillin-resistant Staphylococcus aureus (MRSA) typing in routine epidemiological surveillance. DESIGN:The method is based on polymerase chain reaction (PCR) restriction fragment-length polymorphism (RFLP) following HaeII diges...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/501903
更新日期:2001-05-01 00:00:00
abstract::This study was designed to test the efficacy of a washer-disinfector in eliminating selected healthcare-associated pathogens from surgical instruments. Our results showed that a washer-disinfector was extremely effective in eliminating microorganisms (>7-log(10) reduction), including vegetative and spore-forming bacte...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/676867
更新日期:2014-07-01 00:00:00
abstract::We evaluated vancomycin use in a hospital with endemic vancomycin-resistant enterococci and a vancomycin restriction program. Only 68% of vancomycin was prescribed appropriately. Inappropriate use was due primarily to empirical therapy. In the patients with a microbiological diagnosis following empirical therapy, 83% ...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/501548
更新日期:1999-01-01 00:00:00
abstract::OBJECTIVE To describe the investigation and control of a cluster of Serratia marcescens bacteremia in a 505-bed tertiary-care center. METHODS Cluster cases were defined as all patients with S. marcescens bacteremia between March 2 and April 7, 2014, who were found to have identical or related blood isolates determined...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2017.137
更新日期:2017-09-01 00:00:00
abstract::Studies in the 1970s and 1980s suggested that environmental surface contamination played a negligible role in the endemic transmission of healthcare-associated infections. However, recent studies have demonstrated that several major nosocomial pathogens are shed by patients and contaminate hospital surfaces at concent...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章,评审
doi:10.1086/660363
更新日期:2011-07-01 00:00:00
abstract:OBJECTIVE:To determine whether alcohol hand disinfection is an effective alternative to traditional agents for the pre-surgical scrub. DESIGN:A prospective clinical trial of a 70% isopropanol pre-surgical hand disinfectant. SETTING:The operating room suites at two hospital sites in British Columbia. METHODS:Cases we...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/501835
更新日期:2001-10-01 00:00:00
abstract:BACKGROUND:States, including Illinois, have passed legislation mandating the use of International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) codes for reporting healthcare-associated infections, such as methicillin-resistant Staphylococcus aureus (MRSA). OBJECTIVE:To evaluate the sens...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/651665
更新日期:2010-05-01 00:00:00
abstract::OBJECTIVE To define how often methicillin-resistant Staphylococcus aureus (MRSA) is spread from resident to resident in long-term care facilities using whole-genome sequencing DESIGN Prospective cohort study SETTING A long-term care facility PARTICIPANTS Elderly residents in a long-term care facility METHODS Cultures ...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2016.41
更新日期:2016-06-01 00:00:00
abstract:OBJECTIVE:To determine the appropriateness of antibiotic prophylaxis regimens for major surgery in Korea. DESIGN:Retrospective study using a written survey for each patient who underwent arthroplasty, colon surgery, or hysterectomy. SETTING:Six tertiary hospitals in Seoul and Gyeonggi Province. PATIENTS:From each ho...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/519180
更新日期:2007-08-01 00:00:00