Oral insulin enhances cell proliferation and decreases enterocyte apoptosis during methotrexate-induced mucositis in the rat.

abstract：:We evaluated the diagnostic delay (time from first symptoms to diagnosis) in 100 pediatric patients with Crohn disease (CD) and 75 patients with ulcerative colitis (UC). Median (interquartile range) diagnostic delay in patients with CD was 4 (2-8) (range 0-82) months compared with 2 (1-7) (range 0-52) months in patien...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Schoepfer AM,Vavricka S,Safroneeva E,Fournier N,Manser C,Frei P,Deltenre P,Rogler G,Straumann A,Ezri J,Nydegger A,Braegger C

更新日期：2017-02-01 00:00:00

abstract：:Hepatic ornithine carbamoyltransferase (OCT) and alcohol dehydrogenase (ADH) activities were measured in six groups of rats: (A) fed a severe zinc-(Zn-) deficient diet (1.98 ppm) for 5 weeks; (B) pair-fed control for group (A); (C) fed a less severe Zn-deficient diet (6.10 ppm) for 5 weeks; (D) pair-fed control for gr...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Indo Y,Nagata N,Higashi A,Matsuda I,Kashiwabara N,Nakashima I

更新日期：1985-04-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to develop a questionnaire evaluating the frequency of symptoms over time of concomitant childhood bladder and bowel dysfunctions (CBBDs) in 5- to 12-year-old children and to assess its feasibility and aspects of validity and reliability. METHODS:The Childhood Bladder and Bowel Dysf...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： van Engelenburg-van Lonkhuyzen ML,Bols EMJ,Bastiaenen CHG,Benninga MA,de Bie RA

更新日期：2017-06-01 00:00:00

abstract：INTRODUCTION:Recently, significant interest from families and healthcare providers has arisen to use blenderized tube feedings (BTF). Although many institutions are providing this nutritional option, literature documenting outcomes and safety is lacking. METHODS:A retrospective chart review was performed on pediatric ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Kernizan D,Mintz D,Colin M,Lee M,Yoakam L,Chen YP,Iofel E,Koniaris S,Weidner M

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the accuracy of reduced-dose ¹³C-urea breath test (¹³C-UBT) and early sampling of exhaled breath for the detection of Helicobacter pylori infection in children and adolescents. METHODS:Patients up to 20 years old that underwent upper gastrointestinal endoscopy with gastr...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Pacheco SL,Ogata SK,Machado RS,Patrício FR,Pardo ML,Kawakami E

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVES:For the pediatric population, upper reference limits (URLs) for aminotransferase levels have not been established. The prevalence of high aminotransferase levels provides important information regarding the burden of liver disease in the current childhood obesity endemic. METHODS:We set the URL of alanine a...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Park SH,Park HY,Kang JW,Park J,Shin KJ

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Starch is an important source of energy for children with cystic fibrosis, but little is known about their capacity to digest it. METHODS:A 13C breath test was used to measure starch digestion and oxidation in 16 children with cystic fibrosis (median [range] age, 7.9 [4-15] years; 7 girls, 9 boys) and 5 nor...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Amarri S,Harding M,Coward WA,Evans TJ,Weaver LT

更新日期：1999-09-01 00:00:00

abstract：OBJECTIVES:Functional dyspepsia (FD) is a functional abdominal pain disorder. There is paucity of data on the economic impact of FD in children. Primary aim of our study was to estimate annual evaluation cost ("diagnosis and visit" cost) and secondary aim was to identify potential prognostic factors of FD in children. ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Mani J,Madani S,Thomas R

更新日期：2020-04-01 00:00:00

abstract：OBJECTIVES:To analyze the long-term results of Boerema anterior gastropexy using the Visick grading system in a university teaching hospital. METHODS:Retrospective review of 247 children with severe or complicated gastroesophageal reflux disease (GERD). Patients who underwent primary gastropexy between 1990 and 2001 w...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Kloek JJ,van de Laar GA,Deurloo JA,Aronson DC,Benninga MA,Taminiau JA,Heij HA

更新日期：2006-07-01 00:00:00

abstract：OBJECTIVE:Diarrhea is frequently observed among critically ill children (CIC) admitted for intensive care. There is increasing evidence that probiotics decrease the incidence of acute infectious and nosocomial and antibiotic induced diarrhea amongst children hospitalized in nonintensive care settings. Despite theoretic...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Srinivasan R,Meyer R,Padmanabhan R,Britto J

更新日期：2006-02-01 00:00:00

abstract：:Major events in gastrointestinal ontogeny occur in the infant rat in association with weaning, resulting in striking alterations in small intestinal structure and function. Although the dietary changes attendant to weaning are not essential for the initiation of these events, dietary nutrients have been shown to parti...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Castillo RO,Feng JJ,Stevenson DK,Kerner JA,Kwong LK

更新日期：1990-02-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to evaluate erosive esophagitis healing and symptom improvement with once-daily esomeprazole in children ages 12 to 36 months with endoscopically or histologically proven gastroesophageal reflux disease (GERD). PATIENTS AND METHODS:Data from children ages 12 to 36 months were includ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Tolia V,Gilger MA,Barker PN,Illueca M

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:In patients with biliary atresia (BA), liver fibrosis and cirrhosis commonly occur even after Kasai hepatoportoenterostomy. Although liver biopsy is the gold standard to evaluate liver fibrosis, it is invasive and may result in life-threatening complications. The aspartate aminotransferase-to-platelet ratio ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Kim SY,Seok JY,Han SJ,Koh H

更新日期：2010-08-01 00:00:00

abstract：:R-1 anti-reticulin antibodies (ARA) were present in sera of 10 of the 12 children who subsequently fulfilled the ESPGAN diagnostic criteria for celiac disease (CD), but was not found in any children in the age-matched control groups, viz., severely malnourished (n = 20), acute gastroenteritis (n = 23), normally nouris...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Khoshoo V,Bhan MK,Unsworth DJ,Kumar R,Walker Smith JA

更新日期：1988-11-01 00:00:00

abstract：:This randomized, double-blind trial determined whether adding 90 mmol/L of alanine with a reduction in glucose to 90 mmol/L (alanine ORS) improves the efficacy of the standard oral rehydration solution (WHO-ORS). One hundred twenty-nine males aged 3-48 months with weight for length greater than or equal to 70% of NCHS...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Sazawal S,Bhatnagar S,Bhan MK,Saxena SK,Arora NK,Aggarwal SK,Kashyap DK

更新日期：1991-05-01 00:00:00

abstract：:Parasitic infection of the gut is highly prevalent in developing countries and contributes to the severe malnutrition associated with persistent diarrhoea in children. Using random faecal alpha 1-antitrypsin measurements as an index of protein-losing enteropathy, we examined children with and without parasitic infecti...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Sullivan PB,Lunn PG,Northrop-Clewes CA,Farthing MJ

更新日期：1992-11-01 00:00:00

abstract：BACKGROUND:An increased incidence of necrotizing enterocolitis (NEC) has been noted in infants who are born to mothers with chorioamnionitis. HYPOTHESIS:Our objective was to test the hypothesis that newborn rat pups born to mothers exposed to prenatal lipopolysaccharide during pregnancy would be more susceptible to in...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Giannone PJ,Nankervis CA,Richter JM,Schanbacher BL,Reber KM

更新日期：2009-03-01 00:00:00

abstract：:Breast milk jaundice has been reported to be associated with increased lipase activity and elevated free fatty acid (FFA) concentrations within breast milk. We have previously shown that bile salts are present in small concentrations in breast milk and the aim of this study was to examine the relationship of bile salt...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Forsyth JS,Donnet L,Ross PE

更新日期：1990-08-01 00:00:00

abstract：OBJECTIVES:A large retrospective multicentre study was conducted in Spain to evaluate the efficiency of the new European Society for Pediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN) criteria for the diagnosis of coeliac disease (CD). METHODS:The study protocol was approved by the ethics committee of Hos...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Donat E,Ramos JM,Sánchez-Valverde F,Moreno A,Martinez MJ,Leis R,Peña-Quintana L,Castillejo G,Fernández S,Garcia Z,Ortigosa L,Balmaseda E,Marugán JM,Eizaguirre FJ,Lorenzo H,Barrio J,Ribes-Koninckx C,SEGHNP Working Group

更新日期：2016-02-01 00:00:00

abstract：OBJECTIVES:The present study aims to identify the genotype-phenotype correlation in children with Peutz-Jeghers Syndrome (PJS) through the analysis of STK11 gene mutations in the context of clinical and pathological characteristics. METHOD:In this observational cohort study, the clinical characteristics of 18 families...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Zhao HM,Yang YJ,Duan JQ,Ouyang HJ,Liu L,Yi LC,Xiao ZH,Zheng Y,Peng L,Attard TM,Li DY,You JY

更新日期：2019-02-01 00:00:00

abstract：OBJECTIVES:To evaluate the safety of lansoprazole in children between 1 and 11 years of age. METHODS:In a phase I/II, open-label, multicenter (11 sites) study, children with symptomatic gastroesophageal reflux disease (GERD), erosive esophagitis (> or = grade 2), and/or esophageal pH < 4 for > 4.2% of the 24-hour peri...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Tolia V,Fitzgerald J,Hassall E,Huang B,Pilmer B,Kane R 3rd

更新日期：2002-01-01 00:00:00

abstract：:The permeability of the intestine was studied in 39 children (1 month to 3 years of age) with diarrhoea and in 28 children (6 months to 15 years of age) undergoing duodenal biopsy. Permeability was measured by differential absorption from an isotonic oral load containing 3.5 g lactulose, 0.5 g L-rhamnose, 0.5 g D-xylo...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Ford RP,Menzies IS,Phillips AD,Walker-Smith JA,Turner MW

更新日期：1985-08-01 00:00:00

abstract：OBJECTIVES:Patients with inflammatory bowel disease (IBD) are at risk for vitamin and mineral deficiencies because of long-term inflammation in the gut mucosa and decreased oral intake. The aim of the study is to investigate the prevalence of vitamin and zinc deficiencies in patients with newly diagnosed IBD compared w...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Alkhouri RH,Hashmi H,Baker RD,Gelfond D,Baker SS

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Many mathematical equations based on height have been developed to estimate the esophageal length (EL) in children. The aim of this study was to confirm whether the preexisting and most frequently used equation by Strobel et al is accurate in calculating the EL in our pediatric population. Our...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Moreau B,Kambites S,Lévesque D

更新日期：2013-08-01 00:00:00

abstract：:Examination of 136 children who were referred to the Pediatric Gastroenterology Clinic at Yale-New Haven Hospital for chronic or severe diarrhea between 1977 and 1981 revealed that 31 patients (22.8%) had serum immunoglobulin levels below the 5th percentile for age. Twenty-four of these 31 patients (77.4%) had normal ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Glassman M,Grill B,Gryboski J,Dwyer J

更新日期：1983-01-01 00:00:00

abstract：:This study was designed to determine the cardiac, respiratory, and arousal responses to an esophageal acid infusion test in near-term infants free from neurological, gastroesophageal, and cardiopulmonary disease at time of testing during active sleep. Eight infants (gestational age 28-37.5 weeks, postconceptional age ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Ramet J,Egreteau L,Curzi-Dascalova L,Escourrou P,Dehan M,Gaultier C

更新日期：1992-08-01 00:00:00

abstract：:A 13-year-old girl with a 1-year history of elevated serum alanine transferase was hospitalized because of liver failure. Low prothrombin time (12%) prevented needle liver biopsy. Because of a high titer of antismooth-muscle antibodies (1:500), a tentative diagnosis of "autoimmune" chronic active hepatitis was made an...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Maggiore G,Bernard O,Hadchouel M,Alagille D

更新日期：1985-08-01 00:00:00

abstract：:The effects of changes in diet on antral gastrin-like immunoreactivities and antral and corporal somatostatin-like immunoreactivities were studied in three groups of young male rats. Group 1 rats were weaned physiologically, group 2 rats received only breast milk, and group 3 rats were fed milk until 20 days of age an...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Okahata H,Nishi Y,Muraki K,Kumamoto T,Sumioka M,Sumii K,Hide M,Tanaka K,Miyachi Y,Usui T

更新日期：1985-06-01 00:00:00

abstract：:Eighteen infants with severe hypernatremic dehydration secondary to acute gastroenteritis were rehydrated during the 1st day with an oral glucose electrolyte solution containing 60 mmol sodium/L at a mean rate of 120 ml/kg/24 h. These 18 children were safely treated with oral therapy alone. No convulsions were observe...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Blum D,Brasseur D,Kahn A,Brachet E

更新日期：1986-03-01 00:00:00

abstract：OBJECTIVES:Failure-to-thrive is defined as an abnormally low weight and/or height for age. The term "nonorganic failure-to-thrive" (NOFT) has been used to describe "failure-to-thrive" without an obvious cause underlying the growth failure. The purpose of the present study was to compare sensory processing abilities bet...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Yi SH,Joung YS,Choe YH,Kim EH,Kwon JY

更新日期：2015-06-01 00:00:00