Abstract：
:Many fundamental cellular processes depend on enzymes that utilize chemical energy to catalyse unfavourable reactions. Certain classes of ATPases provide a particularly vivid example of the process of energy conversion, employing cycles of nucleotide turnover to move and/or rearrange biological polymers such as proteins and nucleic acids. Four well-characterized classes of ATP-dependent protein/nucleic acid translocases and remodelling factors are found in all three domains of life (bacteria, archaea and eukarya): additional strand catalytic 'E' (ASCE) P-loop NTPases, GHL proteins, actin-fold enzymes and chaperonins. These unrelated protein superfamilies have each evolved the ability to couple ATP binding and hydrolysis to the generation of motion and force along or within their substrates. The past several years have witnessed the emergence of a wealth of structural data that help explain how such molecular engines link nucleotide turnover to conformational change. In this review, we highlight several recent advances to illustrate some of the mechanisms by which each family of ATP-dependent motors facilitates the rearrangement and movement of proteins, protein complexes and nucleic acids.
journal_name
Mol Microbioljournal_title
Molecular microbiologyauthors
Thomsen ND,Berger JMdoi
10.1111/j.1365-2958.2008.06364.xsubject
Has Abstractpub_date
2008-09-01 00:00:00pages
1071-90issue
5eissn
0950-382Xissn
1365-2958pii
MMI6364journal_volume
69pub_type
杂志文章,评审abstract：:We screened the putative rap-phr (response regulator aspartyl-phosphate phosphatase-phosphatase regulator) systems identified in the Bacillus subtilis genome for a rap gene that affects aprE (alkaline protease gene) expression by using a multicopy plasmid. We found that rapG was involved in the regulation of aprE, whi...
journal_title：Molecular microbiology
pub_type： 杂志文章
doi：10.1046/j.1365-2958.2003.03665.x
更新日期：2003-09-01 00:00:00
abstract：:In this paper we describe the chromosomal location of various loci in Erwinia chrysanthemi strain 3937. Auxotrophic markers were obtained by chemical mutagenesis, antibiotic resistances were isolated spontaneously and mutations in sugar utilization were obtained by means of Mu insertions. These markers were located on...
journal_title：Molecular microbiology
pub_type： 杂志文章
doi：10.1111/j.1365-2958.1989.tb00204.x
更新日期：1989-05-01 00:00:00
abstract：:The endoribonuclease RNase E plays an important role in RNA processing and degradation in Escherichia coli. The construction of an E. coli strain in which the cellular concentration of RNase E can be precisely controlled has made it possible to examine and quantify the effect of RNase E scarcity on RNA decay, gene reg...
journal_title：Molecular microbiology
pub_type： 杂志文章
doi：10.1046/j.1365-2958.2002.02808.x
更新日期：2002-02-01 00:00:00
abstract：:The AbcR small RNAs (sRNAs) are a fascinating example of two highly conserved sRNAs that differ tremendously at the functional level among organisms. From their transcriptional activation to their regulatory capabilities, the AbcR sRNAs exhibit varying characteristics in three well-studied bacteria belonging to the Rh...
journal_title：Molecular microbiology
pub_type： 杂志文章,评审
doi：10.1111/mmi.13869
更新日期：2018-01-01 00:00:00
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journal_title：Molecular microbiology
pub_type： 杂志文章
doi：10.1111/j.1365-2958.2011.07539.x
更新日期：2011-03-01 00:00:00
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journal_title：Molecular microbiology
pub_type： 杂志文章
doi：10.1111/j.1365-2958.2008.06518.x
更新日期：2009-01-01 00:00:00
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journal_title：Molecular microbiology
pub_type： 杂志文章
doi：10.1111/j.1365-2958.1993.tb01171.x
更新日期：1993-03-01 00:00:00
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journal_title：Molecular microbiology
pub_type： 杂志文章
doi：10.1111/j.1365-2958.2005.04803.x
更新日期：2005-09-01 00:00:00
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journal_title：Molecular microbiology
pub_type： 杂志文章
doi：10.1111/mmi.13650
更新日期：2017-05-01 00:00:00
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journal_title：Molecular microbiology
pub_type： 杂志文章
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更新日期：2015-01-01 00:00:00
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journal_title：Molecular microbiology
pub_type： 杂志文章
doi：10.1046/j.1365-2958.1997.5971972.x
更新日期：1997-11-01 00:00:00
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journal_title：Molecular microbiology
pub_type： 杂志文章
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更新日期：2012-05-01 00:00:00
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pub_type： 杂志文章
doi：10.1046/j.1365-2958.1998.00682.x
更新日期：1998-01-01 00:00:00
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journal_title：Molecular microbiology
pub_type： 杂志文章,评审
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更新日期：1997-04-01 00:00:00
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journal_title：Molecular microbiology
pub_type： 杂志文章
doi：10.1111/j.1365-2958.1993.tb01611.x
更新日期：1993-05-01 00:00:00
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journal_title：Molecular microbiology
pub_type： 杂志文章
doi：10.1111/j.1365-2958.1992.tb00859.x
更新日期：1992-05-01 00:00:00
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journal_title：Molecular microbiology
pub_type： 杂志文章
doi：10.1111/j.1365-2958.2009.06985.x
更新日期：2010-01-01 00:00:00
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journal_title：Molecular microbiology
pub_type： 杂志文章
doi：10.1046/j.1365-2958.1996.386918.x
更新日期：1996-02-01 00:00:00
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pub_type： 杂志文章
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更新日期：2006-12-01 00:00:00
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journal_title：Molecular microbiology
pub_type： 杂志文章
doi：10.1111/j.1365-2958.1994.tb00341.x
更新日期：1994-02-01 00:00:00
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pub_type： 杂志文章
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更新日期：2012-10-01 00:00:00
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journal_title：Molecular microbiology
pub_type： 杂志文章
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更新日期：1999-01-01 00:00:00
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journal_title：Molecular microbiology
pub_type： 杂志文章
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更新日期：2005-11-01 00:00:00
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journal_title：Molecular microbiology
pub_type： 杂志文章
doi：10.1111/mmi.13270
更新日期：2016-03-01 00:00:00
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journal_title：Molecular microbiology
pub_type： 杂志文章
doi：10.1111/j.1365-2958.1988.tb00036.x
更新日期：1988-05-01 00:00:00
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journal_title：Molecular microbiology
pub_type： 杂志文章
doi：10.1046/j.1365-2958.2000.01726.x
更新日期：2000-02-01 00:00:00
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journal_title：Molecular microbiology
pub_type： 评论,杂志文章
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更新日期：2006-09-01 00:00:00
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journal_title：Molecular microbiology
pub_type： 评论,杂志文章
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更新日期：2010-10-01 00:00:00
abstract：:Agrobacterium tumefaciens transforms plants by transferring DNA to the plant cell nucleus. The VirB membrane proteins are postulated to form a pore for the transport of the DNA across the bacterial membranes. Immunofluorescence and immunoelectron microscopy were used to study the transport pore complex. Three likely c...
journal_title：Molecular microbiology
pub_type： 杂志文章
doi：10.1046/j.1365-2958.2000.01876.x
更新日期：2000-05-01 00:00:00
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journal_title：Molecular microbiology
pub_type： 杂志文章
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更新日期：2003-02-01 00:00:00
