Serous cystic tumors of the pancreas: when to observe and when to operate: a single-center experience.

Abstract:

BACKGROUND:Pancreatic serous cystic tumors are considered to have a benign biological and clinical course with only few malignant cases. METHODS:We retrospectively analyzed data from 26 patients affected by serous cystic tumors consecutively observed in our Pancreas Unit. We explored the different clinical pictures in operated and nonoperated patients. RESULTS:Eighteen of the 26 patients were female (69%), median age at diagnosis was 61.5 years and 20 patients (77%) underwent surgery. The median diameter of the tumors was greater in patients who underwent surgery than in those who did not (5.5 versus 2.3 cm, p < 0.001). Major pancreatic resections were carried out in 15 of the 20 operated patients (75%). Postoperative morbidity and mortality were 20 and 5%, respectively. During follow-up, there was no observed development of malignancy or any significant increase in the diameter of the lesion among nontreated patients. CONCLUSIONS:In asymptomatic patients with a clear imaging diagnosis of serous cystic tumor a wait and see management should be recommended, with a careful follow-up. Surgery should be suggested in symptomatic patients or when the preoperative diagnosis is doubtful.

journal_name

Dig Surg

journal_title

Digestive surgery

authors

Zanini N,Fantini L,Casadei R,Pezzilli R,Santini D,Calculli L,Minni F

doi

10.1159/000142947

subject

Has Abstract

pub_date

2008-01-01 00:00:00

pages

233-9; discussion 240

issue

3

eissn

0253-4886

issn

1421-9883

pii

000142947

journal_volume

25

pub_type

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