Abstract:
BACKGROUND:In order to diagnose an unsuspected gallbladder carcinoma and to examine whether a differential diagnosis could be made between cancer and noncancerous lesions during surgery, we evaluated the findings of fine structures of various types of gallbladder mucosa. METHODS:We used stereomicroscopy with a dye-contrast technique under water and measured the maximum blood vessel diameters of the gallbladder mucosa: normal gallbladder, chronic cholecystitis, and carcinoma. RESULTS:All normal gallbladders showed fine-reticular-type findings. In chronic cholecystitis, 5.8% of the specimens (n = 69) had fine reticular type, 87.0% had rough reticular type, and 7.2% had atrophic type. All the cases of adenomyomatosis (n = 16) showed rough reticular type. In eight specimens of pancreaticobiliary maljunction, 75% of them showed high reticular type, and the other 25% showed papillary type. The two adenoma specimens showed fine granular type. In five gallbladder carcinomas, the lattice-like pattern completely disappeared and showed rough granular type. The average of maximum vessel diameters in the gallbladder mucosa were 41.0 microm in normal gallbladders, 99.1 microm in patients with chronic cholecystitis, and 614.8 microm in patients with a carcinoma. There were significant differences among them (p < 0.05). CONCLUSION:This study showed that differential diagnosis between cancer and noncancerous lesion is possible by dye-staining mucosal pattern and measurement of maximum vessel diameters by stereoscopic examination.
journal_name
Dig Surgjournal_title
Digestive surgeryauthors
Aoki T,Inoue K,Tsuchida A,Kasuya K,Koyanagi Ydoi
10.1159/000050156subject
Has Abstractpub_date
2001-01-01 00:00:00pages
298-304issue
4eissn
0253-4886issn
1421-9883pii
50156journal_volume
18pub_type
杂志文章abstract:BACKGROUND:In bioartificial liver preparation, serum-contained medium is ordinarily replaced by serum-free medium and hepatocytes are generally cultured at high density. This study was to undertaken to evaluated the dynamic changes in morphology, viability and functions of porcine hepatocytes in serum-free medium at hi...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000064211
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND:Recent trials have shown promising results for the efficacy of gum chewing for the amelioration of postoperative ileus. This finding could have a major clinical impact since gum chewing is relatively harmless and cheap while postoperative ileus has a significant impact on healthcare. METHODS:Systematic revi...
journal_title:Digestive surgery
pub_type: 杂志文章,评审
doi:10.1159/000117822
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND/AIMS:It has recently been reported that rebamipide (OPC-12759) inhibits inflammatory cytokines and activation of neutrophils. The aim of the present study was to investigate the effects of preoperative administration of rebamipide on parameters of systemic inflammatory response syndrome (SIRS) and serum leve...
journal_title:Digestive surgery
pub_type: 临床试验,杂志文章
doi:10.1159/000073645
更新日期:2003-01-01 00:00:00
abstract:BACKGROUND/AIMS:Postoperative urinary retention (POUR) is one of the most frequent complications of epidural anesthesia. This study aims to clarify risk factors of POUR and to estimate the appropriate timing of urethral catheter removal. METHODS:Between September and December 2014, a retrospective cohort study was con...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000490199
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Therapeutic strategies to prevent port site recurrences in laparoscopy surgery of malignancies have not been investigated until now. METHODS:The effects of taurolidine, heparin, and povidone iodine on the growth of rat and human colon adenocarcinoma as well as gallbladder carcinoma were investigated in vitr...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000018754
更新日期:1999-01-01 00:00:00
abstract:BACKGROUND:Pancreatic tuberculosis is usually unsuspected as it can present in various forms. Though an uncommon disease, once diagnosed it is potentially curable. PATIENTS AND METHODS:Retrospective review of the records of 9 patients with histologically proven tuberculosis of the pancreas. RESULTS:In none of the 9 p...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000065832
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND:Mechanical stapling devices are widely used in all fields of surgery as they can cut and sew tissue in a quick and easy manner. However, complications like bleeding or leakage at the staple line are frequently encountered and can have devastating consequences. Recent developments have led to the introduction...
journal_title:Digestive surgery
pub_type: 杂志文章,评审
doi:10.1159/000096648
更新日期:2006-01-01 00:00:00
abstract::Dysgerminomas of the ovary rarely metastasize to abdominal viscera and when they do, the involvement is a part of a disseminated disease. A 30-year-old woman developed isolated duodenopancreatic dysgerminoma 14 years after salpingo-oophorectomy. The clinical picture was complicated by the presence of tuberculous lesio...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000050198
更新日期:2001-01-01 00:00:00
abstract:BACKGROUND:The reduction in plasma cholesterol with increase in large and lower dense LDL (pattern A) obtained by statins is usually associated with a prompt reduction in cardiovascular risk, but after bariatric surgery for morbid obesity a delay of some years is observed. No data regarding LDL pattern are available in...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000068861
更新日期:2003-01-01 00:00:00
abstract:AIMS:To evaluate the role of the Physiological and Operative Severity Score for the enUmeration of Mortality and Morbidity (POSSUM), the Portsmouth variant (p-POSSUM) and the Glasgow Prognostic Score (GPS) in predicting outcome after pancreatic surgery with reference to the International Study Group of Pancreatic Surge...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000313693
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND:Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. The tumor size and mitotic count, typical risk category factors, are difficult to determine preoperatively. This study aimed to evaluate the usefulness of preoperative 18F-fluoro-2-deoxyglucose posit...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000357149
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Although evidence is growing that most patients who need an operation for diverticular disease of the sigmoid colon can be treated by a single-stage procedure, a two-stage procedure will still be necessary in some patients because of significant sepsis or technical difficulties. The outcomes of 65 patients w...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000091444
更新日期:2005-01-01 00:00:00
abstract:BACKGROUND/AIM:Pancreatitis is the most common and feared complication of endoscopic retrograde cholangiopancreatography (ERCP). We previously examined patency of the accessory pancreatic duct (APD) by dye injection endoscopic retrograde pancreatography (ERP). APD patency was found in 43% of 291 control cases who had n...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000286962
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND:Chyle leaks are a rare complication following abdominal surgery. The aim of this study is to describe the management of chyle leaks following surgery for pancreatico-duodenal malignancy. METHODS:Data were collated from a consecutive series of 105 patients who had undergone a pancreatico-duodenectomy for mal...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000108324
更新日期:2007-01-01 00:00:00
abstract::Surgery is the definitive tool in the management of patients with rectal carcinoma. Early failure of treatment remains problematic and is manifest in local recurrence. Development of surgical techniques and inclusion of other treatment modalities aim to reduce the incidence of local recurrence and improve survival. Th...
journal_title:Digestive surgery
pub_type: 杂志文章,评审
doi:10.1159/000085355
更新日期:2005-01-01 00:00:00
abstract:BACKGROUND:The optimal treatment of common bile duct (CBD) stones is controversial, and depends on local expertise, the patient's medical condition and the time of diagnosis. Current practice entails a wide variation in the duration of leaving T tubes in place, anywhere from 7 to 30 days, and in the time to postoperati...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000018612
更新日期:1998-01-01 00:00:00
abstract:BACKGROUND:Sarcomas of the esophagus are rare representing 0.1-1.5% of all esophageal tumors. We report a case of malignant peripheral nerve sheath tumor (MPNST) of the esophagus in a 60-year-old woman. METHODS:The diagnosis was made preoperatively on endoscopic biopsy and confirmed after tumor resection by immunohist...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000051973
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND/AIMS:Because the TNM system disregards the number of lymph nodes dissected and inter-individual differences exist in the number of regional lymph nodes, the lymph node ratio (LNR), which is estimated by dividing the number of metastatic lymph nodes by the number of dissected lymph nodes, has been proposed as...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000355444
更新日期:2013-01-01 00:00:00
abstract::Several methods for assessment of methodological quality in randomized controlled trials (RCTs) have been developed during the past few years. Factors associated with quality in laparoscopic surgery have not been defined till date. The aim of this study was to investigate the relationship between bibliometric and the ...
journal_title:Digestive surgery
pub_type: 杂志文章,评审
doi:10.1159/000381886
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:Laparoscopic sigmoidectomy for diverticulitis has initially been confined to the elective setting. However, open acute sigmoidectomy for perforated diverticulitis is associated with high morbidity rates that might be reduced after laparoscopic surgery. The aim of this systematic review was to assess the feas...
journal_title:Digestive surgery
pub_type: 杂志文章,评审
doi:10.1159/000441150
更新日期:2016-01-01 00:00:00
abstract::The monocyte/macrophage plays a key role in the network of immune reactions. Dependent on activation, it is able to produce various cytokines which act on other cells of the immune system in the sense of upregulation or downregulation. In addition, it presents antigens by the HLA-DR molecule as an initial trigger of a...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000018601
更新日期:1998-01-01 00:00:00
abstract::Hepatocellular adenomas (HCA) are rare benign tumours occurring mainly in women under oral contraceptives. HCA bleed frequently and transform rarely into hepatocellular carcinoma. Identification of genes recurrently mutated in HCA and good genotype/phenotype correlations provided the basis of a pathomolecular classifi...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000268406
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND/AIMS:The management of patients with silent or asymptomatic gallstones remains controversial. The objective of this study is to determine the complications of laparoscopic cholecystectomy performed to treat patients under 50 years of age with asymptomatic gallstones. METHOD:207 patients, 13-49 years of age ...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000018876
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:Surgery for patients with malignant obstructive jaundice carries high morbidity and mortality rates. Preoperative biliary drainage (PBD) has been used in an attempt to improve the outcome in these patients. AIM:To review the evidence in the literature on whether PBD improves postoperative morbidity and mort...
journal_title:Digestive surgery
pub_type: 杂志文章,评审
doi:10.1159/000050105
更新日期:2001-01-01 00:00:00
abstract:BACKGROUND/AIMS:Strictureplasty (SP) or miniresective 'bowel-sparing' techniques (MR) can prevent the risk of intestinal stomia and short bowel syndrome in patients affected by Crohn's disease (CD). The aim of this study was to analyze the perioperative morbidity and mortality in 104 of 138 consecutive patients treated...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000018845
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:Both ectopic pancreatic tissue and malignant insulinoma are rare. We encountered the combination of these rare entities in a patient demonstrating hypoglycemic symptoms. METHOD:A patient with episodic hypoglycemia, non-suppressed serum insulin levels, positive fasting test and a positive localization on bot...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000090998
更新日期:2005-01-01 00:00:00
abstract:BACKGROUND:The aim of this study was to determine whether selection with fluorine-18-deoxyglucose positron emission tomography (FDG-PET) imaging would result in an improved outcome in surgically treated patients with curative resection of colorectal liver metastases (CRLM), stratified by the clinical risk score (CRS) o...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000357351
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:The optimal management approach to pancreatic serous cystic neoplasms (SCNs) is still evolving. METHODS:Consecutive patients with SCN managed at the Liverpool Pancreas Cancer Centre between 2000 and 2013 were retrospectively reviewed. RESULTS:There were 64 patients consisting of 39 women (60.9%) and 25 men...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000442094
更新日期:2016-01-01 00:00:00
abstract::The intestinal barrier function is considered to play an important role in protecting the penetration of luminal antigens, associated with the development of secondary infection and sepsis and the initiation of the multiple organ dysfunction syndrome. The intestinal mucosal barrier against luminal macromolecules and m...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000018651
更新日期:1998-01-01 00:00:00
abstract:BACKGROUND:Positron emission tomography and computed tomography (PET-CT) is established in the staging of esophageal cancer. In this study, an MRI protocol was designed to emulate the anatomical (T1-weighed (T1W) and T2W imaging) and functional information (diffusion-weighted imaging) provided by PET-CT. METHODS:In al...
journal_title:Digestive surgery
pub_type: 临床试验,杂志文章
doi:10.1159/000431292
更新日期:2015-01-01 00:00:00