Posthepatectomy bile leakage: how to manage.

Abstract:

BACKGROUND:Biliary leakage after liver resection continues to be reported. Management of bile leakage has changed in recent years, with nowadays non-surgical procedures as the preferred treatment. METHODS:Biliary leakage and management were assessed in 381 patients who underwent liver resection between January 2005 and April 2011. RESULTS:The overall rate of biliary leakage after liver resection was 5.0%, with a higher incidence in patients who had undergone concomitant hepaticojejunostomy (HJ; 13.6 vs. 3.2%). Hospital stay (p = 0.047), major resections (p = 0.018), operation time (p = 0.011), and relaparotomy (p = 0.002) were risk factors for postoperative bile leakage. Multivariate analysis identified relaparotomy as an independent factor (OR 4.216, p = 0.034). Bile leakage in patients without HJ (n = 10) was managed in 6 patients by percutaneous transhepatic biliary drainage (PTD), and in 3 patients by endoscopic drainage. One patient was treated surgically. All patients with an HJ and postoperative bile leakage (n = 9) underwent PTD. CONCLUSION:The incidence of posthepatectomy biliary leakage has decreased over time, while PTD and endoscopic stenting are effective treatment modalities. PTD is the treatment of choice in bile leakage after resection combined with HJ.

journal_name

Dig Surg

journal_title

Digestive surgery

authors

Hoekstra LT,van Gulik TM,Gouma DJ,Busch OR

doi

10.1159/000335734

subject

Has Abstract

pub_date

2012-01-01 00:00:00

pages

48-53

issue

1

eissn

0253-4886

issn

1421-9883

pii

000335734

journal_volume

29

pub_type

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