Abstract:
BACKGROUND:Positron emission tomography and computed tomography (PET-CT) is established in the staging of esophageal cancer. In this study, an MRI protocol was designed to emulate the anatomical (T1-weighed (T1W) and T2W imaging) and functional information (diffusion-weighted imaging) provided by PET-CT. METHODS:In all, 49 patients with carcinoma of the esophagus underwent PET-CT and whole-body MRI (WBMRI). WBMRI was carried out using dedicated sequences tailored to detect metastatic disease at each area corresponding to the anatomical coverage of PET-CT. Nodal status was determined from histopathology and endoscopic ultrasound biopsy (EUS). RESULTS:PET-CT and WBMRI identified the primary tumor in 46/49 (94%) and 48/49 (98%) patients, respectively. Nodal analysis in patients undergoing surgery (n = 18) yielded sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and accuracy of 27, 100, 100, 47 and 56% for PET-CT, compared with 30, 100, 100, 53 and 61% for WBMRI. When nodal analysis included both surgical specimens and EUS criteria (n = 39), sensitivity, specificity, PPV, NPV and accuracy were 46, 91, 93, 40 and 59% for PET-CT compared with 59, 92, 94, 50 and 67% for WBMRI. Both imaging modalities identified distant metastases in 2 patients. CONCLUSION:WBMRI has similar accuracy to PET-CT in detecting the primary tumor, nodal deposits and for exclusion of systemic metastatic disease.
journal_name
Dig Surgjournal_title
Digestive surgeryauthors
Malik V,Harmon M,Johnston C,Fagan AJ,Claxton Z,Ravi N,O'Toole D,Muldoon C,Keogan M,Reynolds JV,Meaney JFdoi
10.1159/000431292subject
Has Abstractpub_date
2015-01-01 00:00:00pages
397-408issue
5eissn
0253-4886issn
1421-9883pii
000431292journal_volume
32pub_type
临床试验,杂志文章abstract:BACKGROUND/AIMS:The management of patients with silent or asymptomatic gallstones remains controversial. The objective of this study is to determine the complications of laparoscopic cholecystectomy performed to treat patients under 50 years of age with asymptomatic gallstones. METHOD:207 patients, 13-49 years of age ...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000018876
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:Cholecystolithiasis is a common disease. Cholecystectomy is the main treatment method but is associated with various complications in some patients. This study explores a novel, minimally invasive surgery for the removal of calculi and the preservation of the gallbladder using a laparoscope combined with the...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000357823
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND/AIMS:Patients with postoperative pulmonary complications after esophagectomy often have increased mortality. The purpose of the study was to examine the efficacy of preventing postoperative pulmonary complications by an intensive preoperative respiratory rehabilitation (PR) program for esophageal cancer pati...
journal_title:Digestive surgery
pub_type: 杂志文章,随机对照试验
doi:10.1159/000434758
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND/AIMS:Widespread clinical application of islet transplantation remains restricted, because of insufficient methods to prevent rejection and autoimmune destruction of islet grafts. In this study we demonstrate long-term function of islets of Langerhans within a capsule of porcine chondrocytes which may serve a...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000050130
更新日期:2001-01-01 00:00:00
abstract:BACKGROUND:Since carcinoma of the esophagus is usually diagnosed at an advanced stage, many cases of esophageal cancer are beyond possible radical resection and only palliative treatment can be performed in such cases. Therefore, a great deal of discussion has taken place concerning indications for treatment modality, ...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000018619
更新日期:1998-01-01 00:00:00
abstract:INTRODUCTION:Management of pancreatic leak and haemorrhage is complex with high mortality rates. In this study, the results of completion pancreatectomy which was performed as a last resort option were analysed. PATIENTS AND METHODS:25 patients who had completion pancreatectomy from among 677 patients who had pancreat...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000095395
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND:Chyle leaks are a rare complication following abdominal surgery. The aim of this study is to describe the management of chyle leaks following surgery for pancreatico-duodenal malignancy. METHODS:Data were collated from a consecutive series of 105 patients who had undergone a pancreatico-duodenectomy for mal...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000108324
更新日期:2007-01-01 00:00:00
abstract::A case of carcinoma of the colon that metastasized to the lower gingiva is described. The patient who had carcinoma of the colon developed a proliferating lesion at the site of a recent tooth extraction. A few days later, the primary site of the malignancy appeared. The clinical features in such cases were reviewed in...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000050166
更新日期:2001-01-01 00:00:00
abstract::A 64-year-old man with Muir-Torre syndrome (MTS), a condition characterized by the association of multiple sebaceous tumours and kerato-acanthomas with internal malignancies, developed a carcinoma of the ampulla of Vater. This is the 2nd reported ampullary carcinoma in 205 reported cases of MTS, suggesting a higher pr...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000052010
更新日期:2002-01-01 00:00:00
abstract:INTRODUCTION:To elucidate the clinical presentation, diagnosis and management of primary hepatic carcinoid tumours, a literature search was conducted and summarized. MATERIALS AND METHODS:Published primary hepatic carcinoid tumour case reports and series were searched and selected in the Medline, EMBASE and Cochrane L...
journal_title:Digestive surgery
pub_type: 杂志文章,评审
doi:10.1159/000167021
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND/AIMS:Oesophageal intubation remains one of the principal methods of palliation for an obstructing oesophageal carcinoma. We present a case which illustrates a rare but fatal complication of this procedure. METHODS:A 60-year-old female with oesophageal cancer presented with total dysphagia 9 months following...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000018886
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:The optimal treatment of common bile duct (CBD) stones is controversial, and depends on local expertise, the patient's medical condition and the time of diagnosis. Current practice entails a wide variation in the duration of leaving T tubes in place, anywhere from 7 to 30 days, and in the time to postoperati...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000018612
更新日期:1998-01-01 00:00:00
abstract:INTRODUCTION:The extent of optimal gastric resection for proximal gastric cancer (PGC) continues to remain controversial, and a final consensus is yet to be met. The current study aimed to compare the perioperative outcomes, postoperative complications, and overall survival (OS) of proximal gastrectomy (PG) versus tota...
journal_title:Digestive surgery
pub_type: 杂志文章,评审
doi:10.1159/000506104
更新日期:2021-01-01 00:00:00
abstract:BACKGROUND:The role of preoperative upper-gastrointestinal endoscopy for bariatric surgery is still understood only with controversy. The aim of this study was to evaluate the prevalence of endoscopic findings and its impact on perioperative management. METHODS:Patients who underwent bariatric surgery at our center be...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000381811
更新日期:2015-01-01 00:00:00
abstract:AIMS:Describe the characteristics of extraintestinal manifestations complicating ulcerative colitis present preoperatively and determine their evolution after surgery. METHODS:Between 1976 and 1986, 281 patients with ulcerative colitis exhibiting one or more extraintestinal manifestations (EIM) before either IPAA (n =...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000050097
更新日期:2001-01-01 00:00:00
abstract:AIM:To investigate the degree to which specialisation or case-load of the surgeon is associated with the number of lymph nodes isolated from pathology specimens after right-sided hemicolectomy. METHOD:Data from 6 hospitals with well-defined catchment areas included in the Uppsala/Örebro Regional Oncology Centre Colon ...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000354857
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:Morbidity following pancreaticoduodenectomy (PD) has been reported to remain high. This study sought to measure the peak Hounsfield units (HUs) of visceral attenuation in patients undergoing PD and to assess the quality of adipocytes by comparing these measurements with perioperative factors. METHODS:Patien...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000505060
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Surgery for patients with malignant obstructive jaundice carries high morbidity and mortality rates. Preoperative biliary drainage (PBD) has been used in an attempt to improve the outcome in these patients. AIM:To review the evidence in the literature on whether PBD improves postoperative morbidity and mort...
journal_title:Digestive surgery
pub_type: 杂志文章,评审
doi:10.1159/000050105
更新日期:2001-01-01 00:00:00
abstract:BACKGROUND/AIMS:Primary distal bile duct adenocarcinomas (DBDAs) are unusual neoplasms, necessitating pancreaticoduodenectomy for cure. The aims of this study were to evaluate the prognostic importance of lymphatic and perineural invasion, long-term outcome of patients after resection, and differences in outcome with h...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000018798
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:Proinflammatory cytokines like TNF-alpha and IL-8 have been thought to play a pivotal role in the propagation of severe acute pancreatitis (AP) and the development of its systemic complications, particularly acute lung injury. OBJECTIVE:To investigate the effects of pretreatment with hydrocortisone on the p...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000018730
更新日期:1999-01-01 00:00:00
abstract::Tumour recurrence that obstructs the afferent limb, blocking outflow of bile and pancreatic juice, constitutes a major clinical problem after a Whipple procedure. The endoscopic route is often not a possible alternative. Surgery may be difficult and perhaps dangerous to the often very sick patient and decompression wi...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000071760
更新日期:2003-01-01 00:00:00
abstract:OBJECTIVE:To review the current management of achalasia, and the controversies regarding the different treatment options. METHODS:A review of the literature was performed. The key words used were esophageal achalasia, Heller myotomy, endoscopic balloon dilatation, laparoscopic Heller myotomy, and fundoplication. RESU...
journal_title:Digestive surgery
pub_type: 杂志文章,评审
doi:10.1159/000079341
更新日期:2004-01-01 00:00:00
abstract:BACKGROUND/AIMS:Intra-abdominal adhesions typically occur after surgically damaged tissues are situated in apposition, leading to fibrotic connections. The goal of this study was to demonstrate the in vivo efficacy of a cross-linked and insoluble hyaluronic acid (HA) film to reduce postsurgical adhesion in a rat model....
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000253872
更新日期:2009-02-01 00:00:00
abstract:BACKGROUND:A choice of retrosternal or orthotopic route for reconstruction exists after three-phase esophagectomy with cervical anastomosis. Whether the route of reconstruction affects postoperative morbidity, mortality and recurrence patterns remains controversial. STUDY DESIGN:Patients with cancer of the thoracic es...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000070387
更新日期:2003-01-01 00:00:00
abstract:AIM:To prove further the safety of primary closure of the common bile duct. METHOD:Twenty patients among 99 common bile duct explorations underwent primary closure. Pre- and postoperative liver function test, ultrasound and intraoperative cholangiography data, operation time, postoperative complications and the length...
journal_title:Digestive surgery
pub_type: 临床试验,杂志文章
doi:10.1159/000018706
更新日期:1999-01-01 00:00:00
abstract:BACKGROUND/AIMS:Postoperative urinary retention (POUR) is one of the most frequent complications of epidural anesthesia. This study aims to clarify risk factors of POUR and to estimate the appropriate timing of urethral catheter removal. METHODS:Between September and December 2014, a retrospective cohort study was con...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000490199
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Sarcomas of the esophagus are rare representing 0.1-1.5% of all esophageal tumors. We report a case of malignant peripheral nerve sheath tumor (MPNST) of the esophagus in a 60-year-old woman. METHODS:The diagnosis was made preoperatively on endoscopic biopsy and confirmed after tumor resection by immunohist...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000051973
更新日期:2000-01-01 00:00:00
abstract::One of the main reasons for the dismal prognosis of pancreatic ductal adenocarcinoma (PDAC) is its late diagnosis. At the time of presentation, only approximately 15-20% of all patients with PDAC are considered resectable and around 30% are considered borderline resectable. A surgical approach, which is the only curat...
journal_title:Digestive surgery
pub_type: 杂志文章,评审
doi:10.1159/000493466
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:The aim of this study was to determine whether selection with fluorine-18-deoxyglucose positron emission tomography (FDG-PET) imaging would result in an improved outcome in surgically treated patients with curative resection of colorectal liver metastases (CRLM), stratified by the clinical risk score (CRS) o...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000357351
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:The optimal treatment for acute complicated diverticulitis is still a matter of debate. We evaluated outcomes of primary anastomosis with proximal diversion (PAD) versus Hartman's procedure (HP) in acute diverticulitis. METHODS:Using the National Inpatient Sample database, we examined the clinical data of p...
journal_title:Digestive surgery
pub_type: 杂志文章,多中心研究
doi:10.1159/000342549
更新日期:2012-01-01 00:00:00