Malignant peripheral nerve sheath tumor of the esophagus.

Abstract:

BACKGROUND:Sarcomas of the esophagus are rare representing 0.1-1.5% of all esophageal tumors. We report a case of malignant peripheral nerve sheath tumor (MPNST) of the esophagus in a 60-year-old woman. METHODS:The diagnosis was made preoperatively on endoscopic biopsy and confirmed after tumor resection by immunohistochemistry as well as electron microscopy. The patient underwent abdominal-thoracicen bloc esophagectomy with mediastinal lymphadenectomy and intrathoracic esophagogastrostomy. RESULTS:Our therapeutic concept for the first case of a high-grade MPNST (malignant schwannoma) of the esophagus resulted in a recurrence-free interval of 4 years. CONCLUSION:The therapy of choice was abdominal-thoracic en bloc esophagectomy with tumor-free resection margins and esophageal reconstruction with the stomach. After R0-resection we found no indication for adjuvant radio- and/or chemotherapy.

journal_name

Dig Surg

journal_title

Digestive surgery

authors

Manger T,Pross M,Haeckel C,Lippert H

doi

10.1159/000051973

subject

Has Abstract

pub_date

2000-01-01 00:00:00

pages

627-631

issue

6

eissn

0253-4886

issn

1421-9883

pii

51973

journal_volume

17

pub_type

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