Abstract:
BACKGROUND:The aim of this study was to determine whether selection with fluorine-18-deoxyglucose positron emission tomography (FDG-PET) imaging would result in an improved outcome in surgically treated patients with curative resection of colorectal liver metastases (CRLM), stratified by the clinical risk score (CRS) of Fong et al. [Ann Surg 1999;230:309-318]. PATIENTS AND METHODS:Between January 2000 and December 2009, all patients who underwent resection for CRLM from two different university teaching hospitals in the Netherlands were analysed. Patients were stratified by the CRS. RESULTS:In total 613 patients were eligible for analysis. There was no statistical difference in median disease-free survival (DFS) between patients with and without an FDG-PET scan in both low CRS [17 months (95% CI 12-22) vs. 14 months (95% CI 11-17), p = 0.332] and high CRS [14 months (95% CI 7-21) vs. 9 months (95% CI 8-10), p = 0.073]. There was no statistical difference in median overall survival (OS) between patients with and without an FDG-PET scan in both low CRS [64 months (95% CI 54-74) vs. 54 months (95% CI 42-66), p = 0.663] and high CRS [39 months (95% CI 23-55) vs. 41 months (95% CI 34-48), p = 0.903]. CONCLUSION:The present study could not demonstrate that patients selected by an FDG-PET scan before liver resection, and stratified by CRS, have an improvement in DFS or OS.
journal_name
Dig Surgjournal_title
Digestive surgeryauthors
Ayez N,de Ridder J,Wiering B,Oyen WJ,de Wilt JH,Verhoef Cdoi
10.1159/000357351subject
Has Abstractpub_date
2013-01-01 00:00:00pages
451-8issue
4-6eissn
0253-4886issn
1421-9883pii
000357351journal_volume
30pub_type
杂志文章abstract:AIMS:To describe the extremely rare case of an adenomyoma of the papilla of Vater. CASE REPORT:A 42-year-old woman was hospitalized for epigastralgia and high fever. The clinical presentation and endoscopic, biochemical, and radiologic findings led to the diagnostic impression of a dysfunction of the papilla of Vater....
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000050115
更新日期:2001-01-01 00:00:00
abstract::The monocyte/macrophage plays a key role in the network of immune reactions. Dependent on activation, it is able to produce various cytokines which act on other cells of the immune system in the sense of upregulation or downregulation. In addition, it presents antigens by the HLA-DR molecule as an initial trigger of a...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000018601
更新日期:1998-01-01 00:00:00
abstract:BACKGROUND/AIMS:The management of patients with silent or asymptomatic gallstones remains controversial. The objective of this study is to determine the complications of laparoscopic cholecystectomy performed to treat patients under 50 years of age with asymptomatic gallstones. METHOD:207 patients, 13-49 years of age ...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000018876
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:In order to diagnose an unsuspected gallbladder carcinoma and to examine whether a differential diagnosis could be made between cancer and noncancerous lesions during surgery, we evaluated the findings of fine structures of various types of gallbladder mucosa. METHODS:We used stereomicroscopy with a dye-con...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000050156
更新日期:2001-01-01 00:00:00
abstract:BACKGROUND/AIMS:Approximately 20% of patients undergoing surgery for ulcerative colitis will retain their rectum. A single-stage proctocolectomy could be an appropriate procedure in patients who are definitely not candidates for a later restorative procedure, but it is generally not advised in acutely ill patients. The...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000381033
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:The aim of this study was to determine the early postoperative hematological changes after spleen-preserving distal pancreatectomy (SpDP) with preservation of the splenic artery and vein (PSAV). METHODS:We reviewed 53 patients who underwent SpDP with PSAV (n = 21) or distal pancreatectomy with splenectomy (...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000337312
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:Mechanical stapling devices are widely used in all fields of surgery as they can cut and sew tissue in a quick and easy manner. However, complications like bleeding or leakage at the staple line are frequently encountered and can have devastating consequences. Recent developments have led to the introduction...
journal_title:Digestive surgery
pub_type: 杂志文章,评审
doi:10.1159/000096648
更新日期:2006-01-01 00:00:00
abstract::The abdominal cocoon is a rare disease that is characterized by a total or partial encasement of the small bowel by a thick and fibrotic membrane. Thirty-five cases were reported since it was first described. It occurs primarily in females. Preoperative diagnosis is a matter of challenge and usually made at laparotomy...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000065827
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND:Mexican health system structure allows us to study the differences in bile duct injury (BDI) management. The study aimed to assess the differences in patients with complex BDI in 2 different public sector institutions using a new proposed standard terminology. METHODS:Retrospective review (2008-2019) in 2 p...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000509706
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Public hospitals' long waiting lists make outpatient surgery in private facilities very attractive provided a standardized protocol is applied. The aim of this study was to assess this kind of innovative collaboration in abdominal surgery from a clinical and economical perspective. METHODS:All consecutive p...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000330788
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:In bioartificial liver preparation, serum-contained medium is ordinarily replaced by serum-free medium and hepatocytes are generally cultured at high density. This study was to undertaken to evaluated the dynamic changes in morphology, viability and functions of porcine hepatocytes in serum-free medium at hi...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000064211
更新日期:2002-01-01 00:00:00
abstract::A 26-year-old male was admitted to our hospital with a complaint of mild dysphagia. Preoperative examinations revealed a cystic lesion at the lower esophagus, thought to be a bronchogenic cyst. The patient underwent successful thoracoscopic tumor extirpation, assisted by endoscopy, without undergoing major thoracotomy...
journal_title:Digestive surgery
pub_type: 杂志文章,评审
doi:10.1159/000094751
更新日期:2006-01-01 00:00:00
abstract::Despite the fact that laparoscopic hernia repair was already described in 1979, its value has still not been well defined. The standard treatment for uncomplicated primary hernia repair in Europe is an open anterior approach (i.e. Shouldice), and 'tension-free' mesh plug repair in the USA. At present, posterior mesh i...
journal_title:Digestive surgery
pub_type: 杂志文章,评审
doi:10.1159/000018611
更新日期:1998-01-01 00:00:00
abstract:BACKGROUND/AIMS:Primary distal bile duct adenocarcinomas (DBDAs) are unusual neoplasms, necessitating pancreaticoduodenectomy for cure. The aims of this study were to evaluate the prognostic importance of lymphatic and perineural invasion, long-term outcome of patients after resection, and differences in outcome with h...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000018798
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:Little information from prospective clinical trials is available on the influences of surgical approaches on postoperative body compositions and nutritional status. We designed a prospective non-randomized trial to compare postoperative chronological changes in body composition and nutritional status between...
journal_title:Digestive surgery
pub_type: 杂志文章,多中心研究
doi:10.1159/000458714
更新日期:2018-01-01 00:00:00
abstract::Hepatocellular adenomas (HCA) are rare benign tumours occurring mainly in women under oral contraceptives. HCA bleed frequently and transform rarely into hepatocellular carcinoma. Identification of genes recurrently mutated in HCA and good genotype/phenotype correlations provided the basis of a pathomolecular classifi...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000268406
更新日期:2010-01-01 00:00:00
abstract::Anastomotic leakage after colorectal surgery is correlated with considerable morbidity and mortality. Although many studies focus on risk factors and detection, studies on the treatment strategy for colorectal anastomotic leakage are scarce. A national questionnaire amongst 350 members of the Dutch Society for Gastroi...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000346348
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:Since carcinoma of the esophagus is usually diagnosed at an advanced stage, many cases of esophageal cancer are beyond possible radical resection and only palliative treatment can be performed in such cases. Therefore, a great deal of discussion has taken place concerning indications for treatment modality, ...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000018619
更新日期:1998-01-01 00:00:00
abstract:BACKGROUND:Vagus nerve injury (VNI) is a feared complication of antireflux surgery (ARS). The impact of VNI on the functional outcomes of ARS has not yet been evaluated systematically. The aim of this review was to evaluate the impact of VNI on functional and clinical outcome of ARS. METHODS:A systematic search was pe...
journal_title:Digestive surgery
pub_type: 杂志文章,评审
doi:10.1159/000444147
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND/AIMS:Intra-abdominal adhesions typically occur after surgically damaged tissues are situated in apposition, leading to fibrotic connections. The goal of this study was to demonstrate the in vivo efficacy of a cross-linked and insoluble hyaluronic acid (HA) film to reduce postsurgical adhesion in a rat model....
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000253872
更新日期:2009-02-01 00:00:00
abstract:BACKGROUND:Emergency surgery impairs postoperative outcomes in colorectal cancer patients. No study has assessed the relationship between obesity and postoperative results in this setting. OBJECTIVE:To compare the results of emergency surgery for obstructive colon cancer (OCC) in an obese patient population with those...
journal_title:Digestive surgery
pub_type: 杂志文章,多中心研究
doi:10.1159/000497450
更新日期:2020-01-01 00:00:00
abstract::Local invasion of adjacent viscera by colorectal liver metastases (CRLM) is no longer considered an absolute contraindication to curative hepatic resection. A growing number of observational analyses have illustrated the feasibility of such resections; however, the evidence base is at best heterogeneous with a lack of...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000485198
更新日期:2018-01-01 00:00:00
abstract:INTRODUCTION:Percutaneous radiofrequency ablation (PcRFA) provides alternative means of treating patients with unresectable colorectal liver metastases. We previously reported our initial experience in 30 patients treated with PcRFA. We present the final long-term results in these 30 patients. METHODS:The final outcom...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000107717
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVE:To evaluate the role of CT abdomen in the localization of acute lower gastrointestinal bleeding. SUMMARY BACKGROUND DATA:The source of bleed in acute lower gastrointestinal bleeding is often difficult to localize. The role of CT in the evaluation of this group of patients has not been clearly addressed. MET...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000080204
更新日期:2004-01-01 00:00:00
abstract::Surgery is the definitive tool in the management of patients with rectal carcinoma. Early failure of treatment remains problematic and is manifest in local recurrence. Development of surgical techniques and inclusion of other treatment modalities aim to reduce the incidence of local recurrence and improve survival. Th...
journal_title:Digestive surgery
pub_type: 杂志文章,评审
doi:10.1159/000085355
更新日期:2005-01-01 00:00:00
abstract::The introduction and widespread application of minimally invasive surgery has been one of the most important innovations that radically changed the practice of surgery during the last few decades. The application to pancreatic surgery of minimally invasive approach has only recently emerged: both laparoscopic distal p...
journal_title:Digestive surgery
pub_type: 杂志文章,评审
doi:10.1159/000445012
更新日期:2016-01-01 00:00:00
abstract::Laparoscopic gastrectomy for gastric cancer is rapidly becoming popular because of the technical developments and the accumulated data of laparoscopic surgery in gastric cancer patients. The aim of this review is to present the current body of evidence and to highlight controversial issues of laparoscopic gastrectomy ...
journal_title:Digestive surgery
pub_type: 杂志文章,评审
doi:10.1159/000350884
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:Cholecystolithiasis is a common disease. Cholecystectomy is the main treatment method but is associated with various complications in some patients. This study explores a novel, minimally invasive surgery for the removal of calculi and the preservation of the gallbladder using a laparoscope combined with the...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000357823
更新日期:2013-01-01 00:00:00
abstract::In this review, the function of the sphincter of Oddi (SO) is detailed in terms of normal motility, neural and hormonal control of SO function, coordination between gallbladder and SO motility, and correlation of motility of the SO and the duodenum. In addition, SO function tests, such as the morphine Prostigmin test ...
journal_title:Digestive surgery
pub_type: 杂志文章,评审
doi:10.1159/000286464
更新日期:2010-01-01 00:00:00
abstract::Accurate preoperative staging of gastrointestinal malignancies is of major importance in the decision for adequate stage-related therapy. There is evidence that laparoscopy in combination with laparoscopic ultrasound is more accurate in the detection of intra-abdominal metastases than conventional preoperative imaging...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000067600
更新日期:2002-01-01 00:00:00