Abstract:
:With the advent of novel and somewhat effective chemotherapy against pancreas cancer, several groups developed a new interest on locally advanced pancreatic cancer (LAPC). Unresectable tumors constitute up to 80% of pancreatic cancer (PC) at the time of diagnosis and are associated with a 5-year overall survival of less than 5%. To control those tumors locally, with perhaps improved patients survival, significant advances were made over the last 2 decades in the development of ablation methods including cryoablation, radiofrequency ablation, microwave ablation, high intensity focused ultrasound and irreversible electroporation (IRE). Many suggested a call for caution for possible severe or lethal complications in using such techniques on the pancreas. Most fears were on the heating or freezing of the pancreas, while non-thermal ablation (IRE) could offer safer approaches. The multimodal therapies along with high-resolution imaging guidance have created some enthusiasm toward ablation for LAPC. The impact of ablation techniques on primarily non-resectable PC remains, however, unclear.
journal_name
Dig Surgjournal_title
Digestive surgeryauthors
Linecker M,Pfammatter T,Kambakamba P,DeOliveira MLdoi
10.1159/000445021subject
Has Abstractpub_date
2016-01-01 00:00:00pages
351-9issue
4eissn
0253-4886issn
1421-9883pii
000445021journal_volume
33pub_type
杂志文章,评审abstract:BACKGROUND/AIM:Delay of laparoscopic cholecystectomy after the diagnosis of biliary colic may increase the probability of recurrent emergency admission while awaiting elective cholecystectomy. The aim of this study was to compare the possible advantages and safety of urgent laparoscopic cholecystectomy (ULC) with elect...
journal_title:Digestive surgery
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000085300
更新日期:2005-01-01 00:00:00
abstract:BACKGROUND:Gas in the mesenteric or portal veins (PVG) is an uncommon entity. It was first described only in patients with mesenteric ischemia and bowel gangrene. Later, several reports described other causes for PVG in which conservative treatment was successful. In the past, the diagnosis was made by vague signs in a...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000069388
更新日期:2003-01-01 00:00:00
abstract:BACKGROUND/AIMS:Because the TNM system disregards the number of lymph nodes dissected and inter-individual differences exist in the number of regional lymph nodes, the lymph node ratio (LNR), which is estimated by dividing the number of metastatic lymph nodes by the number of dissected lymph nodes, has been proposed as...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000355444
更新日期:2013-01-01 00:00:00
abstract:INTRODUCTION:To determine the best imaging modality for preoperative detection, characterization and measurement of colorectal liver metastases (CRLM) after neoadjuvant chemotherapy (NAC). METHODS:A total of 79 lesions in 15 patients with CRLM were included. Following NAC, all patients received multislice liver CT (MS...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000322390
更新日期:2011-01-01 00:00:00
abstract::Minimally invasive surgery has been shown to offer many advantages to general surgical patients but has not been widely adopted for colorectal disease. Initial fears surrounding the oncological safety of laparoscopic colectomies have largely subsided but the technical challenges still remain. Surgical robots or telema...
journal_title:Digestive surgery
pub_type: 杂志文章,评审
doi:10.1159/000081350
更新日期:2004-01-01 00:00:00
abstract:BACKGROUND/AIMS:Oesophageal intubation remains one of the principal methods of palliation for an obstructing oesophageal carcinoma. We present a case which illustrates a rare but fatal complication of this procedure. METHODS:A 60-year-old female with oesophageal cancer presented with total dysphagia 9 months following...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000018886
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND/AIMS:Graft failure is a critical complication associated with vascular occlusion in esophageal reconstruction with a free jejunal graft following pharyngolaryngoesophagectomy. In this study, we evaluated the usefulness of intramucosal pH (pHi) measurement using a tonometer to assess the graft viability. MET...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000102902
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVE:To propose guidelines for treatment based on the study of early and late outcome after various surgical procedures for sclerosing encapsulating peritonitis (SEP). PRIMARY BACKGROUND DATA: SEP is rare. The main complication is intestinal obstruction. Ideal treatment is resection of the membrane, whenever possi...
journal_title:Digestive surgery
pub_type: 杂志文章,多中心研究,评审
doi:10.1159/000018681
更新日期:1998-01-01 00:00:00
abstract:AIMS:The present study was designed to evaluate the effects of perioperative treatment with TNP-470 on the resistance of colonic anastomoses. TNP-470 is a drug that was developed as an inhibitor of angiogenesis. METHODS:A colonic anastomosis was constructed in Sprague-Dawley rats. From 4 days before surgery to 4 days ...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000018820
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:In bioartificial liver preparation, serum-contained medium is ordinarily replaced by serum-free medium and hepatocytes are generally cultured at high density. This study was to undertaken to evaluated the dynamic changes in morphology, viability and functions of porcine hepatocytes in serum-free medium at hi...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000064211
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND/AIMS:Approximately 20% of patients undergoing surgery for ulcerative colitis will retain their rectum. A single-stage proctocolectomy could be an appropriate procedure in patients who are definitely not candidates for a later restorative procedure, but it is generally not advised in acutely ill patients. The...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000381033
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:The prognosis of patients with pancreatic cancer is poor. This is mainly caused by the late diagnosis, the aggressive biology and the lack of effective treatment modalities. Adenoviral gene therapy has the potential to selectively treat both primary tumor and (micro)metastatic tissue. METHODS:This review pr...
journal_title:Digestive surgery
pub_type: 杂志文章,评审
doi:10.1159/000145981
更新日期:2008-01-01 00:00:00
abstract::As well as the pronounced effect on body mass index (BMI), bariatric surgery is increasingly recognized as being associated with improvements in morbidity and mortality in a range of conditions, from airways disease to cancer. In metabolic disease, the impact of bariatric surgery is particularly obvious with marked im...
journal_title:Digestive surgery
pub_type: 杂志文章,评审
doi:10.1159/000351440
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:The aim of this study was to determine the early postoperative hematological changes after spleen-preserving distal pancreatectomy (SpDP) with preservation of the splenic artery and vein (PSAV). METHODS:We reviewed 53 patients who underwent SpDP with PSAV (n = 21) or distal pancreatectomy with splenectomy (...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000337312
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND/AIM:Pancreatic cancer has a dismal prognosis. Ampullary cancer (defined as cancer of the ampulla of Vater or the distal common bile duct) has a better prognosis and is thought to be a biologically different tumor. The aim of this study was to find factors that could predict survival after radical (R-0) resec...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000100917
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:Management of leakages of the gastrojejunal anastomosis after laparoscopic Roux-en-Y gastric bypass (LRYGB) can be complex. New endoscopic techniques such as covered stents and over-the-scope clips (OTCs) have been developed and are valuable alternative therapeutic options to reoperation and drainage. The ai...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000358849
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Mexican health system structure allows us to study the differences in bile duct injury (BDI) management. The study aimed to assess the differences in patients with complex BDI in 2 different public sector institutions using a new proposed standard terminology. METHODS:Retrospective review (2008-2019) in 2 p...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000509706
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVE:Systemic and/or local interleukin-6 (IL-6) reportedly plays an active role in the progression and prognosis of thoracic esophageal squamous cell carcinoma (TESCC). We assessed the associations between IL-6 and IL-6 receptor (IL-6R) genetic polymorphisms, tumoral IL-6 expression and survival rates following su...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000336952
更新日期:2012-01-01 00:00:00
abstract:INTRODUCTION:In the management of pancreatic cystic neoplasms (PCN), size plays a crucial role as the expression of disease progression. While many evidences regarding the natural history of growing pancreatic cysts exist, almost no data are available regarding cysts with a reduction in size. METHODS:Radiological and ...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000485199
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:The optimal treatment for acute complicated diverticulitis is still a matter of debate. We evaluated outcomes of primary anastomosis with proximal diversion (PAD) versus Hartman's procedure (HP) in acute diverticulitis. METHODS:Using the National Inpatient Sample database, we examined the clinical data of p...
journal_title:Digestive surgery
pub_type: 杂志文章,多中心研究
doi:10.1159/000342549
更新日期:2012-01-01 00:00:00
abstract::The conventional methods of making an ileal J pouch require an enterotomy to introduce a linear stapler. We devised a new surgical technique that removes any need for this enterotomy by using both circular and linear staplers. We applied this method to two patients who underwent a total colectomy for ulcerative coliti...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000092843
更新日期:2006-01-01 00:00:00
abstract:AIMS:To assess the safety and feasibility of minimally invasive esophagectomy and selected three-field lymphadenectomy with the right bronchial occlusion in left semi-prone position under artificial pneumothorax. METHODS:Thoracoscopic-laparoscopic subtotal esophagectomy and selected three-field lymphadenectomy were pe...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000371747
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:Mechanical stapling devices are widely used in all fields of surgery as they can cut and sew tissue in a quick and easy manner. However, complications like bleeding or leakage at the staple line are frequently encountered and can have devastating consequences. Recent developments have led to the introduction...
journal_title:Digestive surgery
pub_type: 杂志文章,评审
doi:10.1159/000096648
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND:Vagus nerve injury (VNI) is a feared complication of antireflux surgery (ARS). The impact of VNI on the functional outcomes of ARS has not yet been evaluated systematically. The aim of this review was to evaluate the impact of VNI on functional and clinical outcome of ARS. METHODS:A systematic search was pe...
journal_title:Digestive surgery
pub_type: 杂志文章,评审
doi:10.1159/000444147
更新日期:2016-01-01 00:00:00
abstract::One of the possible long-term complications following an ileoanal pouch procedure is the development of malignancy in the mucosa of the rectal stump. Only 10 such cases have been reported so far. We report the case of a 23-year-old male who had ulcerative colitis with high-grade dysplasia and underwent an ileoanal pou...
journal_title:Digestive surgery
pub_type: 杂志文章,评审
doi:10.1159/000068855
更新日期:2003-01-01 00:00:00
abstract::Infectious complications in surgical patients often originate from the intestinal microflora. In the critically ill patient, small bowel motility is disturbed, leading to bacterial overgrowth and subsequent bacterial translocation due to dysfunction of the gut mucosal barrier. The optimal prophylactic strategy should ...
journal_title:Digestive surgery
pub_type: 杂志文章,评审
doi:10.1159/000088053
更新日期:2005-01-01 00:00:00
abstract:BACKGROUND AND AIM:Most patients with hepatic metastases from colorectal carcinoma are unsuitable for resection. Radiofrequency ablation (RFA) has been applied to such lesions at laparotomy. This study aimed to evaluate the less invasive approach of percutaneous RFA. METHOD:Patients with unresectable liver metastases ...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000080886
更新日期:2004-01-01 00:00:00
abstract::Hepatocellular adenomas (HCA) are rare benign tumours occurring mainly in women under oral contraceptives. HCA bleed frequently and transform rarely into hepatocellular carcinoma. Identification of genes recurrently mutated in HCA and good genotype/phenotype correlations provided the basis of a pathomolecular classifi...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000268406
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND:External drainage is the traditional surgical therapy for infected pancreatic pseudocyst, although associated with high morbidity and mortality rates. In this study it was determined whether internal drainage is feasible with acceptable postoperative morbidity and recurrence rates. METHODS:A retrospective c...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000018776
更新日期:1999-01-01 00:00:00
abstract:BACKGROUND:Tata Memorial Centre (TMC) is a high-volume centre for pancreatic tumour resections. We found a continually increasing referral of pancreatic tumours for re-evaluation for surgery, after an initial unsuccessful attempt at resection. AIM:To evaluate reasons of initial in-operability, the feasibility of re-op...
journal_title:Digestive surgery
pub_type: 杂志文章
doi:10.1159/000489275
更新日期:2019-01-01 00:00:00