Function and dysfunction of the sphincter of Oddi.

Abstract:

:In this review, the function of the sphincter of Oddi (SO) is detailed in terms of normal motility, neural and hormonal control of SO function, coordination between gallbladder and SO motility, and correlation of motility of the SO and the duodenum. In addition, SO function tests, such as the morphine Prostigmin test (Nardi test), perfusion manometry, microtransducer manometry, and cholescintigraphy, are explained. Subsequently, the pathophysiology, diagnosis, and treatment of SO dysfunction, including SO stenosis and dyskinesia, are described and discussed in detail. SO manometry and endoscopic sphincterotomy are effective to treat SO dysfunction, but symptoms of the patient must be severe enough to justify these invasive procedures for diagnosis and treatment.

journal_name

Dig Surg

journal_title

Digestive surgery

authors

Tanaka M

doi

10.1159/000286464

subject

Has Abstract

pub_date

2010-01-01 00:00:00

pages

94-9

issue

2

eissn

0253-4886

issn

1421-9883

pii

000286464

journal_volume

27

pub_type

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