Malignant insulinoma in ectopic pancreatic tissue.

Abstract:

BACKGROUND:Both ectopic pancreatic tissue and malignant insulinoma are rare. We encountered the combination of these rare entities in a patient demonstrating hypoglycemic symptoms. METHOD:A patient with episodic hypoglycemia, non-suppressed serum insulin levels, positive fasting test and a positive localization on both ultrasound and somatostatin receptor scintigraphy by (111)I-labelled octreotide, was operated and investigated. RESULTS:(111)I-labelled octreotide-guided surgery was performed and a tumor adjacent to the ligament of Treitz was extirpated. Follow-up was uneventful. Histopathology revealed a malignant insulinoma. The patient is currently under close surveillance. CONCLUSION:The rare combination of an insulinoma in ectopic pancreatic tissue, where the usual diagnostic endoscopic ultrasound revealed an extrapancreatic mass, is described. This was followed by a positive somatostatin receptor scintigraphy, enabling both radio-guided surgery and future treatment of developing recurrent disease or metastases.

journal_name

Dig Surg

journal_title

Digestive surgery

authors

Hennings J,Garske U,Botling J,Hellman P

doi

10.1159/000090998

subject

Has Abstract

pub_date

2005-01-01 00:00:00

pages

377-9

issue

5

eissn

0253-4886

issn

1421-9883

pii

90998

journal_volume

22

pub_type

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