Abstract:
OBJECTIVES:To establish the feasibility of conducting a randomised controlled trial to evaluate the efficacy of acupuncture in the treatment of mild-to-moderate depression. Control group intervention, blinding of treatment, outcome measures and the acceptability of such a trial amongst participants were key factors to be addressed. The findings from this study will be used to determine the design of a phase III randomised controlled trial. DESIGN:Nineteen participants were recruited through general practices in London, UK. Participants were randomly assigned on a 2:1 basis to either 12 sessions of verum acupuncture or 12 sessions of sham acupuncture (control). Sham acupuncture involved actual needling but at sites considered to be unrelated to depression. MAIN OUTCOME MEASURES:The Beck's Depression Inventory (BDI) and the RAND 36 Item Health Survey 1.0 (RAND) were completed at baseline and at the end of treatment or at treatment dropout. All participants also attended a brief qualitative interview at the end of the study. RESULTS:Treatment dropout was low and there were high levels of patient enthusiasm for a study of acupuncture. Referrals from General Practitioners (GPs) were lower than expected. The sham control method successfully maintained participant blinding to treatment and enabled the specific (or active) component of an acupuncture intervention to be isolated and its efficacy assessed. The outcome measures were sensitive enough to record changes in depressive symptoms and quality of life and are appropriate for use in a larger trial. CONCLUSIONS:This feasibility study has provided important information that can be used to guide the design and methodology of a full-randomised controlled trial.
journal_name
Complement Ther Medjournal_title
Complementary therapies in medicineauthors
Whiting M,Leavey G,Scammell A,Au S,King Mdoi
10.1016/j.ctim.2007.07.005subject
Has Abstractpub_date
2008-04-01 00:00:00pages
87-91issue
2eissn
0965-2299issn
1873-6963pii
S0965-2299(07)00088-Xjournal_volume
16pub_type
杂志文章,随机对照试验abstract::Sickle cell disease (SCD) is a genetic disorder characterized by hemolysis, end-organ damage, inflammation, and pain. Recurrent and unpredictable episodes of acute pain due to vaso-occlusive crises are a unique feature of SCD. Many patients also develop lifelong chronic pain. Opioids are the primary method of pain tre...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章,评审
doi:10.1016/j.ctim.2020.102394
更新日期:2020-06-01 00:00:00
abstract:BACKGROUND:Biofield therapies, such as laying on of hands, are used in association with Conventional Medicine as Spiritist "passe", among others. The aim of this study was to evaluate anxiety, depression, pain, muscle tension and well-being, as well as physiological parameters in cardiovascular inpatients submitted to ...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ctim.2016.11.008
更新日期:2017-02-01 00:00:00
abstract:AIMS:To outline acupuncturists' perceptions of treating patients with rheumatoid arthritis (RA), exploring the impact of practitioner affiliation to a traditional or western theoretical base. METHODS:Qualitative study utilising Grounded Theory Method. Nineteen acupuncturists were chosen via theoretical sampling. In-de...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2006.09.008
更新日期:2007-06-01 00:00:00
abstract:OBJECTIVE:The objective was to assess the effects of massage compared to guided relaxation on stress perception and well-being among older adults. DESIGN:A randomised pilot study enrolled adults ages 60 and older to receive 50 min, twice weekly massage therapy or guided relaxation sessions. Questionnaires were adminis...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ctim.2007.01.004
更新日期:2007-09-01 00:00:00
abstract:BACKGROUND:This is the first part of a larger spectrum systematic review which aims to identify and evaluates the effectiveness of all different non-pharmacological acupuncture techniques used for COPD. In this first publication, we describe the results of filiform needle acupuncture METHODS: Randomised controlled tria...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章,meta分析
doi:10.1016/j.ctim.2019.08.016
更新日期:2019-12-01 00:00:00
abstract:BACKGROUND:Inconsistencies exist with regard to effect of maternal vitamin D supplementation on infant vitamin D status. The inconsistencies could be attributed to numerous factors, such as duration of intervention and dosage, among others. In this work, we conducted a systematic review and meta-analysis to determine t...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章,评审
doi:10.1016/j.ctim.2020.102491
更新日期:2020-08-01 00:00:00
abstract::Traditional Chinese Medicine (TCM) is a growing phenomenon around the world. However, despite its historical role in Chinese society, there has been limited research on exploring the nature of TCM practitioner-patient interactions in the Chinese context. This study used 10 hours audio recordings of consultations to el...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2020.102516
更新日期:2020-08-01 00:00:00
abstract:OBJECTIVE:To study the effectiveness of electro-acupuncture with behavior therapy on preschool children with attention deficit hyperactivity disorder (ADHD). METHODS:180 preschool children with ADHD diagnosed by DSM-IV were classified into three subtypes: predominantly inattentive subtype (PI subtype, 60 cases), predo...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ctim.2010.08.002
更新日期:2010-10-01 00:00:00
abstract:BACKGROUND:Merkel cell carcinoma (MCC) is a rare, aggressive, neuroendocrine skin tumor with frequent local recurrence, lymph node involvement, distant metastasis, and a high mortality rate. Viscum album extracts (VAE) are a widely used adjunct in cancer treatment and show cytotoxic and immune-modulating effects. CASE...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2018.04.001
更新日期:2018-06-01 00:00:00
abstract::Traditional Chinese medicine (TCM) has long justified its practice on empirical phenomenology. Questions remain, however, as to the legitimacy of this approach and its relevance to TCM practice and educational developments in the 21st century. General medical practice (GMP) has used practice-based data collected over ...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章,评审
doi:10.1016/j.ctim.2006.06.006
更新日期:2007-12-01 00:00:00
abstract:OBJECTIVES:To systematically review Clinical Practice Guidelines (CPGs) for the management of menopause-related vasomotor symptoms (VMS) to 1) identify those that include Natural Health Products (NHPs); 2) identify which NHPs were included and the evidence supporting the recommendation for the place in therapy; and 3) ...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2019.102285
更新日期:2020-03-01 00:00:00
abstract::While the chronic effects of certain styles of yoga on cardiometabolic factors have been investigated, little is known about the acute effects of a single yoga session on these outcomes. Moreover, vinyasa yoga's potential to modulate cardiometabolic outcomes has not been established. The purpose of this study is to de...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2020.102585
更新日期:2020-10-07 00:00:00
abstract::Established in 2004, the Pediatric Complementary and Alternative Medicine Research & Education (PedCAM) Network (www.pedcam.ca) is a multidisciplinary national and international network focused on pediatric research and education with the vision of safe and effective use of complementary and alternative medicine (CAM)...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2011.03.002
更新日期:2013-04-01 00:00:00
abstract:OBJECTIVE:To evaluate the effects of Sanyinjiao (SP6) with electroacupuncture on labour pain in women during the labour process. METHODS:A total of 350 women in labour from three centres were randomly divided into the electroacupuncture group (acupuncture group), the sham electroacupuncture group (sham group) and the ...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ctim.2010.09.001
更新日期:2011-01-01 00:00:00
abstract:OBJECTIVES:To investigate whether a footbath inhibits spasticity in the hemiplegic lower limbs of post-stroke patients. DESIGN:Randomized, controlled study. SETTING:Rehabilitation education and research hospital. INTERVENTIONS:Twenty-two post-stroke patients were randomly allocated to control or experimental groups....
journal_title:Complementary therapies in medicine
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ctim.2014.09.006
更新日期:2014-12-01 00:00:00
abstract:OBJECTIVES:This study was designed to determine the effects of fenugreek seed (FS) on serum irisin levels, blood pressure, and liver and kidney function in patients with type 2 diabetes mellitus (T2DM). METHODS:In an 8-week randomized controlled clinical trial, T2DM patients (n = 50) were assigned to the intervention ...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ctim.2020.102315
更新日期:2020-03-01 00:00:00
abstract:OBJECTIVE:To examine South Australian acupuncturists' attitudes towards the use of research evidence and concurrently identify predicative factors associated with the uptake and implementation of research evidence. METHODS:Questionnaires were mailed out to the entire South Australian acupuncturist population (n=94). T...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2007.08.002
更新日期:2008-08-01 00:00:00
abstract:OBJECTIVES:Growing interest in integrative medicine motivates examination of who seeks integrative care, and why. By examining differences in demographics and complementary and alternative medicine (CAM) use between patients recruited from Japanese Kampo (traditional herbal medicine) versus biomedical clinics, this stu...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2019.06.003
更新日期:2019-10-01 00:00:00
abstract::Writers on homoeopathy frequently refer to classical homoeopathy, usually with the implication that this is the most complete and authoritative version of Hahnemann's views. However, such claims do not correspond with the historical facts. Homoeopathy arrived in the USA early in the 19th century and there underwent co...
journal_title:Complementary therapies in medicine
pub_type: 历史文章,杂志文章,评审
doi:10.1016/s0965-2299(99)80085-5
更新日期:1999-06-01 00:00:00
abstract:BACKGROUND & OBJECTIVE(S):Obesity is a worldwide epidemic and a common medical condition associated with a variety of chronic diseases. Cereal beta-glucans are soluble fibers with potential health benefits. A number of randomized controlled trials (RCTs) have investigated the effect of cereal beta-glucan consumption on...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章,meta分析
doi:10.1016/j.ctim.2019.01.018
更新日期:2019-04-01 00:00:00
abstract:OBJECTIVES:To assess the experiences of a veteran initiated horticultural therapy garden during their 28-day inpatient Substance Abuse Residential Rehabilitation Treatment Program (SARRTP). DESIGN:Retrospective study. SETTING:Veterans Affairs Medical Center (VAMC), Salem, Virginia, USA INTERVENTIONS: Group interviews...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2017.10.013
更新日期:2018-02-01 00:00:00
abstract:OBJECTIVES:To evaluate the effects of a specially designed power yoga program (YOGA) on bradykinesia, rigidity, muscular performance and quality of life in older patients with PD. DESIGN:Randomized controlled trial. SETTING:University laboratory, US. INTERVENTION:Twenty-six patients with mild to moderate PD were ran...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ctim.2016.01.007
更新日期:2016-04-01 00:00:00
abstract:AIMS:To assess patterns of diagnosis, including concordance, and treatment within a clinical trial of traditional acupuncture for low back pain. SETTING:In a pragmatic randomised controlled clinical trial, 148 patients with low back pain, of between 4 weeks and 12 months duration, were randomised to the offer of indiv...
journal_title:Complementary therapies in medicine
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/S0965-2299(03)00125-0
更新日期:2004-03-01 00:00:00
abstract:OBJECTIVES:Because the use of complementary and alternative medicine (CAM) is increasing among veterans, understanding more about the characteristics of veterans who use CAM is increasingly important. Studies reporting on predictors of use almost always discuss CAM in the aggregate, yet each CAM modality represents a u...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2016.08.004
更新日期:2016-10-01 00:00:00
abstract:OBJECTIVE:Our goal in this study aims to explain the polypharmacological mechanism at the molecular level responsible for the effectiveness of a traditional Chinese medicine (TCM) prescription FTZ to treat hyperlipidemia and related disease. DESIGN:By MDL(®) ISIS_Base 2.5, we constructed a compound database based on t...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2014.08.002
更新日期:2014-10-01 00:00:00
abstract:OBJECTIVE:To identify the effect of some herbal products on insulin resistance. Regarding the scientific evidences existing about ginger, this research was therefore carried out to identify the effect of ginger supplementation on insulin resistance and glycemic indices in diabetes mellitus. METHODS:This is a randomize...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ctim.2013.12.017
更新日期:2014-02-01 00:00:00
abstract:OBJECTIVE:To investigate how individuals expressed rationales for their beliefs regarding efficacy of acupuncture. METHODS:Qualitative data from participants of two different randomized sham-controlled trials, of relaxing (non-cancer volunteers of the general population) or antiemetic (patients with cancer undergoing ...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ctim.2018.04.006
更新日期:2018-08-01 00:00:00
abstract::Many case studies and several controlled clinical trials have indicated the effectiveness of hypnotherapy for some medical conditions. However, because of methodological inadequacies hypnotherapy is still criticized for not having strong scientific evidence to support its claims. While randomized placebo-controlled cl...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2007.04.005
更新日期:2008-02-01 00:00:00
abstract:OBJECTIVES:To compare mental relaxation and slow breathing as adjunctive treatment in patients of essential hypertension by observing their effects on blood pressure and other autonomic parameters like heart rate, respiratory rate, peripheral skin temperature, electromyographic activity of the frontalis muscle and skin...
journal_title:Complementary therapies in medicine
pub_type: 临床试验,杂志文章
doi:10.1016/j.ctim.2005.11.007
更新日期:2006-06-01 00:00:00
abstract:OBJECTIVE:Few studies have examined the use of alternative therapies among adolescents. This study examines the predictors of Native Hawaiian healer preference in the treatment of physical or emotional problems as well as the predictors of healer use. DESIGN:This study is a longitudinal cross-sectional design. SETTIN...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章,多中心研究
doi:10.1016/s0965-2299(02)90000-2
更新日期:2001-12-01 00:00:00