Abstract:
:Sickle cell disease (SCD) is a genetic disorder characterized by hemolysis, end-organ damage, inflammation, and pain. Recurrent and unpredictable episodes of acute pain due to vaso-occlusive crises are a unique feature of SCD. Many patients also develop lifelong chronic pain. Opioids are the primary method of pain treatment in SCD; however, continued use is associated with several adverse effects. Integrative approaches to treating pain in SCD are increasingly being explored to prevent the side effects associated with opioids. In this review, we highlight the mechanisms of pain in SCD and describe mechanism-based integrative approaches for treating pain.
journal_name
Complement Ther Medjournal_title
Complementary therapies in medicineauthors
Sagi V,Argueta DA,Kiven S,Gupta Kdoi
10.1016/j.ctim.2020.102394subject
Has Abstractpub_date
2020-06-01 00:00:00pages
102394eissn
0965-2299issn
1873-6963pii
S0965-2299(20)30624-5journal_volume
51pub_type
杂志文章,评审abstract::This article describes the experience of the authors in producing a booklet to provide information on complementary and alternative therapies (CAM) in their local area. The practical steps needed to produce a booklet are described, including ways of involving local general practitioners, meeting with local therapists,...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1054/ctim.2000.0413
更新日期:2001-03-01 00:00:00
abstract:OBJECTIVE:School children undergo stress, which could impact their psychological functions and cognitive abilities. Yoga practices have been found useful in enhancing psychological functions and performance. The current study was planned to evaluate a yoga-based relaxation technique's efficacy as an extracurricular act...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2020.102606
更新日期:2020-11-13 00:00:00
abstract:OBJECTIVE:The effect of silymarin supplementation on metabolic status and oxidative stress of subjects with type 2 diabetes mellitus (T2DM) has not been conclusively studied. Therefore, the efficacy of silymarin supplementation in these patients was assessed through a meta-analysis. METHODS:The following databases wer...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章,meta分析
doi:10.1016/j.ctim.2018.08.010
更新日期:2018-12-01 00:00:00
abstract:OBJECTIVES:While several cross-sectional studies have examined psychological correlates of complementary and alternative medicine (CAM) use and cancer, few prospective longitudinal investigations have been reported. This study examined whether CAM use moderated distress and quality of life (HRQoL) from pre- to post-can...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2011.09.008
更新日期:2012-02-01 00:00:00
abstract:BACKGROUND:It has been observed that mitochondrial dysfunction is associated with an increased risk of metabolic syndrome. There is growing evidence that hyperactivity of the hypothalamus-pituitary-adrenal (HPA) axis and hormone (testosterone and growth hormone) deficiency may lead to metabolic syndrome. Recent studies...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ctim.2015.12.001
更新日期:2016-02-01 00:00:00
abstract:OBJECTIVES:To investigate whether a footbath inhibits spasticity in the hemiplegic lower limbs of post-stroke patients. DESIGN:Randomized, controlled study. SETTING:Rehabilitation education and research hospital. INTERVENTIONS:Twenty-two post-stroke patients were randomly allocated to control or experimental groups....
journal_title:Complementary therapies in medicine
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ctim.2014.09.006
更新日期:2014-12-01 00:00:00
abstract:BACKGROUND AND AIMS:Colonoscopy can be painful and uncomfortable. Aromatherapy is often used for the relief of anxiety or discomfort. Recently, it has been reported that olfactory stimulation induces various physiological effects. We investigated the effects of aromatherapy on anxiety and abdominal discomfort during co...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ctim.2017.08.012
更新日期:2017-10-01 00:00:00
abstract:OBJECTIVES:To examine what experienced acupuncture practitioners and researchers considered key aspects of treatment to promote cephalic version for women with a breech presentation, and to establish a treatment protocol through consensus to guide the self administration of moxa by pregnant women. METHODS AND DESIGN:T...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2013.12.005
更新日期:2014-02-01 00:00:00
abstract:OBJECTIVE:To develop a simplified Tai Chi exercise program for frail older adults. DESIGN:For phase I, using a focus group, 40 frail Taiwanese older adults were interviewed to explore their viewpoints on Tai Chi and have been reported elsewhere. This paper emphasized on the phase II of the study in which the older adu...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2006.05.002
更新日期:2006-09-01 00:00:00
abstract:BACKGROUND:Gamat (sea-cucumber) is a natural occurring fauna which is popularly used as traditional medication in Southeast Asian countries. There have been many animal studies done on its' biochemical properties and its' effects in vivo. The effect of gamat on human cutaneous wounds was studied using a split-skin graf...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2018.10.006
更新日期:2018-12-01 00:00:00
abstract:OBJECTIVE:To evaluate the effect of functional-task training on activities of daily living (ADL) in people with Parkinson`s Disease. METHODS:We searched five databases (Cinahl, Embase, Medline, Pedro and CENTRAL). The included studies were assessed on therapeutic validity and risk of bias. We classified the quality of...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章,meta分析
doi:10.1016/j.ctim.2018.12.008
更新日期:2019-02-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:The objective of meta-analysis of randomized controlled trials (RCTs) was to evaluate the effects of probiotic supplementation on metabolic status in patients with neurological disorders. METHODS:The following databases were search up to April 2019: Pubmed, Scopus, Google scholar, Web of Scien...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章,评审
doi:10.1016/j.ctim.2020.102507
更新日期:2020-09-01 00:00:00
abstract:OBJECTIVES:The roots and rhizomes of licorice (Glycyrrhiza glabra L.) are used in traditional Persian medicine for the treatment of numerous diseases. A chronic cough is a non-specific reaction to irritation anywhere in the respiratory system. It usually lasts for more than eight weeks. The current study aimed to evalu...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ctim.2020.102324
更新日期:2020-03-01 00:00:00
abstract:OBJECTIVES:To examine the long-term effects of foot-bathing therapy, using different water temperatures, on the sleep quality of older adults living in nursing homes. DESIGN:A quasi-experimental study design with non-equivalent control group. SETTINGS:Thirty participants were recruited from a nursing home in Gyeong-g...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ctim.2016.02.005
更新日期:2016-06-01 00:00:00
abstract:OBJECTIVE:Observe the clinical efficacy of l-3-n-Butylphthalide (NBP) in acute ischemic stroke (AIS) patients within 24 h after intravenous thrombolysis using recombinant tissue plasminogen activator (hereafter termed "IT"). METHODS:One-hundred and seventy-eight patients with AIS were divided randomly into two groups:...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2020.102442
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND:Over one-third of cardiac patients practice Mind-Body Therapy (MBT), particularly women. Considering women are less likely to engage in conventional physical activity, few studies have examined why MBT is well-accepted by women. OBJECTIVES:To qualitatively explore gender differences in the motivations for, ...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2008.04.009
更新日期:2008-12-01 00:00:00
abstract:OBJECTIVE:To evaluate the effect of ethnicity as a predictor of the use of complementary and alternative medicine (CAM) among patients with diabetes. DESIGN AND SETTINGS:A 16-item questionnaire investigating CAM use was distributed among patients attending the Taking Control of Your Diabetes (TCOYD) educational confer...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2010.09.007
更新日期:2010-12-01 00:00:00
abstract:AIMS:To examine the effects of aromatherapy massage on anxiety and sleep quality in patients undergoing colorectal surgery in the preoperative period. BACKGROUND:In recent years, there has been an increase in the number of studies conducted on aromatherapy massage. It is stated that studies conducted on aromatherapy m...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ctim.2017.12.002
更新日期:2018-02-01 00:00:00
abstract:OBJECTIVES:Infantile colic is a common benign disease occurring in early infancy that may have a great impact on family life. In the present study, the effectiveness and safety of the complex homeopathic medicine Enterokind was compared with Simethicone for treating infantile colic. DESIGN AND SETTING:Current data wer...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ctim.2019.05.026
更新日期:2019-08-01 00:00:00
abstract:BACKGROUND:Complementary and alternative medicine (CAM) use is increasingly popular amongst general populations around the world with women constituting substantial CAM users. However, self-prescribed CAM use does raise potential safety concerns and so it is important to identify those risk factors associated with self...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2015.06.011
更新日期:2015-10-01 00:00:00
abstract:OBJECTIVE:Sauna-bathing is an ancient tradition that is gaining popularity across the world as a wellness tool. There is a growing body of medical evidence supporting the role of saunas, or whole-body thermotherapy, as a form of treatment for a range of health issues. However, the demographics, motivations and experien...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2019.03.012
更新日期:2019-06-01 00:00:00
abstract:OBJECTIVE:To study the effectiveness of electro-acupuncture with behavior therapy on preschool children with attention deficit hyperactivity disorder (ADHD). METHODS:180 preschool children with ADHD diagnosed by DSM-IV were classified into three subtypes: predominantly inattentive subtype (PI subtype, 60 cases), predo...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ctim.2010.08.002
更新日期:2010-10-01 00:00:00
abstract:OBJECTIVE:This study illustrates that direct electrical stimulation (ES) improve functional recovery and time of return to work evaluated by prognostic scoring system after ulnar nerve injury. DESIGN:The Rosén and Lundborg (R&L) protocol, Disabilities of the Arm, Shoulder and Hand (DASH) scores, and electromyography w...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2015.12.003
更新日期:2016-02-01 00:00:00
abstract:OBJECTIVE:Besides conventional drugs, various vaginal disorders are often treated with complementary and alternative medicines. Different natural products are often used in treatment of genital infections. The aim is to present a case of treatment of vaginal infection with a garlic clove. METHODS:A detailed interview ...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2018.05.017
更新日期:2018-08-01 00:00:00
abstract:OBJECTIVES:To see how lay people group or classify various CAM therapies. DESIGN:Nearly 600 adults rated 39 relatively familiar branches of complementary medicine on four dimensions: whether they had heard of it, whether they think they know how it works; whether they had tried it; and a rating of efficacy on a 10-poi...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1054/ctim.2000.0355
更新日期:2000-06-01 00:00:00
abstract:OBJECTIVE:To identify the effect of some herbal products on insulin resistance. Regarding the scientific evidences existing about ginger, this research was therefore carried out to identify the effect of ginger supplementation on insulin resistance and glycemic indices in diabetes mellitus. METHODS:This is a randomize...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ctim.2013.12.017
更新日期:2014-02-01 00:00:00
abstract:OBJECTIVES:The physiological changes that occur during pregnancy, including increased blood volume and cardiac output, can affect hemodynamic control, most profoundly with positional changes that affect venous return to the heart. By using Osteopathic Manipulative Treatment (OMT), a body-based modality theorized to aff...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ctim.2013.08.008
更新日期:2013-12-01 00:00:00
abstract:OBJECTIVE:The evidence for the effect of remote ischemic postconditioning(RIpostC) on autonomic function in patients with acute ischemic stroke(AIS) is lacking and the neural mechanism underlying the protection of RIpostC remains speculative. This trial was aimed to evaluated the efficiency of RIpostC on autonomic func...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2020.102541
更新日期:2020-11-01 00:00:00
abstract:BACKGROUND:Biofield therapies, such as laying on of hands, are used in association with Conventional Medicine as Spiritist "passe", among others. The aim of this study was to evaluate anxiety, depression, pain, muscle tension and well-being, as well as physiological parameters in cardiovascular inpatients submitted to ...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ctim.2016.11.008
更新日期:2017-02-01 00:00:00
abstract::This brief lifestyle intervention, including a vegan diet rich in fresh fruits and vegetables, whole grains and various legumes, nuts and seeds, significantly improved health risk factors and reduced systemic inflammation as measured by circulating CRP. The degree of improvement was associated with baseline CRP such t...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2014.11.001
更新日期:2015-02-01 00:00:00