Abstract:
OBJECTIVES:Association between acute pancreatitis and acute viral hepatitis (AVH) is more frequent than previously thought. Most cases are hepatitis A or B virus related. Only 6 cases of acute pancreatitis with acute hepatitis E virus (HEV)-related hepatitis has been reported so far. METHODS:We analyzed the hospital records of 334 patients of acute pancreatitis admitted from December 2004 to March 2006. Seven patients had an associated AVH. RESULTS:Of these, 4 had HEV-related and 3 had hepatitis A virus-related AVH. All but one were young males who presented with abdominal pain during the second to third week of hepatitis illness. None had a history of biliary colic, alcoholism, abdominal trauma, or intake of drugs causing pancreatitis or a family history of pancreatitis. Mean bilirubin was 10.74 mg/dL; alanine aminotransferase levels, 482.85 IU/L; and serum amylase, 1263.57 IU/L. All patients had an imaging evidence of pancreatitis. Two patients with HEV-related disease had grades D to E pancreatitis. All were managed conservatively and recovered completely. CONCLUSIONS:Association between acute pancreatitis and nonfulminant viral hepatitis is now more frequently recognized. Seen more commonly in young males during the second and third week of hepatitis illness, HEV might be associated with severe pancreatitis.
journal_name
Pancreasjournal_title
Pancreasauthors
Bhagat S,Wadhawan M,Sud R,Arora Adoi
10.1097/MPA.0b013e31815d9d53subject
Has Abstractpub_date
2008-05-01 00:00:00pages
424-7issue
4eissn
0885-3177issn
1536-4828pii
00006676-200805000-00014journal_volume
36pub_type
杂志文章相关文献
PANCREAS文献大全abstract:OBJECTIVES:We aim to examine the predictive effect of the total number of examined lymph nodes on N stage and survival in pancreatic neuroendocrine neoplasms (pNENs) and to determine the optimal threshold. METHODS:A pNENs data set from 2004 to 2013 was extracted from the Surveillance, Epidemiology, and End Result data...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/MPA.0000000000000987
更新日期:2018-02-01 00:00:00
abstract:INTRODUCTION:Proinflammatory cytokines play an important role in the development of type 1 diabetes. Lisofylline (LSF) is a novel anti-inflammatory compound that specifically inhibits proinflammatory cytokine production and action. AIM:To investigate the effect of LSF on diabetes prevention. METHODOLOGY:A mouse with ...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-200305000-00021
更新日期:2003-05-01 00:00:00
abstract:OBJECTIVES:Many patients with recurrent acute and chronic pancreatitis who are candidates for total pancreatectomy and islet cell autotransplantation (TPIAT) undergo endoscopic retrograde cholangiopancreatography (ERCP). However, little is known on the impact of ERCP on TPIAT outcomes. We aimed to explore the effect of...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/MPA.0000000000001188
更新日期:2019-01-01 00:00:00
abstract::Reports of a so-called "mucin-producing tumor of the pancreas" are increasing worldwide. Although the clinicopathologic features and therapeutic strategies of this tumor have been enthusiastically investigated, there are still many unanswered questions regarding this ailment. In this study, problems in the diagnosis a...
journal_title:Pancreas
pub_type: 杂志文章,评审
doi:10.1097/00006676-199804000-00025
更新日期:1998-04-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to determine if there had been any change in the number of solid-pseudopapillary neoplasm (SPN) cases detected and their evaluation or management over time. METHODS:A systematic review of SPN was performed of all articles published in English in PubMed and Scopus. RESULTS:A total of...
journal_title:Pancreas
pub_type: 杂志文章,评审
doi:10.1097/MPA.0000000000000061
更新日期:2014-04-01 00:00:00
abstract::Neonatal rats treated with streptozotocin on day 5 after birth (n5-STZ model) exhibited, when fully grown, a frank basal hyperglycemia (17.4 +/- 0.7 vs. 6.6 +/- 0.2 mmol/L in nondiabetic rats), a specific failure of glucose-induced insulin release, and hyperresponse to arginine. To investigate whether or not chronic c...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-199101000-00008
更新日期:1991-01-01 00:00:00
abstract:OBJECTIVES:Oxidative stress has been implicated in the pathogenesis of chronic pancreatitis (CP) and pancreatic cancer (PC). The study aim was to assess the oxidative stress markers and antioxidant defense system in patients with CP and those with PC. METHODS:Activities of superoxide dismutase 1 (SOD1), catalase (CAT)...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/MPA.0b013e318288360a
更新日期:2013-05-01 00:00:00
abstract::The effects of manganese (Mn2+) on phosphorylation activity in the rat pancreas were examined in an in vitro phosphorylation assay and by sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) of endogenous proteins. Several histones were phosphorylated in the presence of pancreatic supernatant obtained ...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-199009000-00015
更新日期:1990-09-01 00:00:00
abstract::In a patient with pancreatic cancer, an arterial anomaly was observed that apparently consisted of the congenital absence of the celiac axis and the replacement of the pancreaticoduodenal arcade by an anomalous vessel. The complete or near-complete arterial flow to the liver and spleen depended upon this anomalous pre...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-198910000-00013
更新日期:1989-01-01 00:00:00
abstract:OBJECTIVES:Angiogenesis plays a major role in tumor progression and metastasis; however, its role in pancreatic cancer (PC) remains unclear. The aim of the study was to explore the cumulative evidence concerning the impact of microvessel density (MVD), an estimator of angiogenesis, on resected PC patients. METHODS:A s...
journal_title:Pancreas
pub_type: 杂志文章,meta分析
doi:10.1097/MPA.0000000000001237
更新日期:2019-02-01 00:00:00
abstract:OBJECTIVES:Single-institution studies have shown improved outcomes among patients with a pathologic complete response (pCR) following neoadjuvant therapy. We sought to evaluate the impact of pCR and near-complete response (nCR) on overall survival (OS) using a large national database. METHODS:The National Cancer Datab...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/MPA.0000000000001590
更新日期:2020-08-01 00:00:00
abstract:OBJECTIVE:To evaluate the effects of iodine contrast media and gadoteric acid in acute necrotizing pancreatitis. METHODS:Fifty rabbits were distributed in 5 groups: 10 rabbits were assigned in the control group (group 5) and 40 rabbits were assigned in the pancreatitis group, wherein acute necrotizing pancreatitis was...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/mpa.0b013e3180a6f366
更新日期:2007-11-01 00:00:00
abstract::Clinical and translational research is critical for the development of improvement in care of pancreatic diseases. Major concerns are the lack of dedicated trainees in pancreatic research and the difficulty for the remaining trainees to develop independent research careers to be included into the pancreas research com...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/MPA.0b013e3181c63422
更新日期:2010-04-01 00:00:00
abstract:OBJECTIVE:Given the lack of consensus on surveillance guidelines after pancreatic neuroendocrine tumor (PanNET) resection, we assessed outcomes in a large cohort of patients with nonmetastatic, surgically resected PanNETs. METHODS:Data of patients with PanNETs resected between 1990 and 2017 were retrospectively collec...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/MPA.0000000000001477
更新日期:2020-02-01 00:00:00
abstract::Sarcophytol A (SaA), a cembrane-type diterpene isolated from the marine soft coral Sarcophyton glaucum showed anticancer and cancer preventive effects in two different experiments. Growth of transplanted human pancreatic cancer cells (MIA paca-2, 1 x 10(7)) in nude mice (BALB/C 4W female) (Experiment 1) and pancreatic...
journal_title:Pancreas
pub_type: 杂志文章
doi:
更新日期:1994-07-01 00:00:00
abstract:OBJECTIVES:The 2012 international consensus guidelines for the management of intraductal papillary mucinous neoplasm (IPMN) of the pancreas stratified patients into 2 clinical categories, "high-risk stigmata" and "worrisome features," and recommended different therapeutic strategies for these groups. The aim of this st...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/MPA.0000000000000199
更新日期:2014-11-01 00:00:00
abstract:OBJECTIVE:Green tea polyphenols (GTPs) are naturally occurring antioxidants acting through pathways that include reactive oxygen species and nuclear factor kappa B (NF-kappaB). This study investigates the effect of GTPs in a cerulein-induced murine model of acute pancreatitis (AP). METHODS:Male CD mice (median weight,...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/MPA.0b013e3181b28d11
更新日期:2009-11-01 00:00:00
abstract::Increased activity of various proteases is observed in both human and experimental pancreatitis; however, the information on the effects of specific protease inhibitors on the disease is limited. In this study we show that a novel elastase inhibitor, guamerin-derived synthetic peptide (GDSP), improves the parameters o...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-199904000-00003
更新日期:1999-04-01 00:00:00
abstract:OBJECTIVE:Pancreatic stellate cells (PSCs) are important players in pancreatic fibrosis and are major contributors to the extracellular matrix proteins observed with the stromal response characteristic of pancreatic ductal adenocarcinoma (PDAC). Pancreatic stellate cells are also believed to secrete soluble factors tha...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/MPA.0b013e318214efaf
更新日期:2011-05-01 00:00:00
abstract:OBJECTIVE:The purpose of this study is to assess the prognostic significance of late parenchymal pancreas necrosis as observed on serial contrast-enhanced computed tomographic (CT) scan. METHODS:Eighty-four patients with acute necrotizing pancreatitis were included. All initial CT scans were examined on complete contr...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/MPA.0b013e31802e01ec
更新日期:2007-03-01 00:00:00
abstract::We diverted bile and pancreatic juice from jejunal blind loops of different lengths in conscious rats to see if the pancreatic secretory response was dependent on the length of the jejunal blind loop. Short-term bile and pancreatic juice diversion from a short jejunal blind loop, representing only 8-10% of the total l...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-199901000-00007
更新日期:1999-01-01 00:00:00
abstract:OBJECTIVES:Exocrine pancreatic secretion contributes to limit pathogenic bacteria-associated diarrhea. Bovine colostrum, used in the treatment of diarrhea, reduces symptoms originating from gut pathogenic bacteria overgrowth. We hypothesized that bovine colostrum may stimulate the exocrine pancreatic secretion. METHOD...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/MPA.0b013e318192eb83
更新日期:2009-04-01 00:00:00
abstract:INTRODUCTION:Although cell kinetics of the gastrointestinal mucosa has been extensively examined, that of the pancreas has not been fully analyzed. AIM:To determine the renewal rate of pancreatic cells directly. METHODOLOGY:Postnatal proliferative activity and cellular renewal of the parenchymal cells in ICR mouse pa...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-200203000-00006
更新日期:2002-03-01 00:00:00
abstract::Human pure pancreatic juice (PPJ) and serum were analyzed for free fatty acids (FFAs) to study whether the damage to pancreatic cell membranes in pancreatitis is reflected as abnormal FFAs concentration and composition. Patients consisted of 13 normal controls, 7 patients with acute pancreatitis (AP) in remission, and...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-198804000-00017
更新日期:1988-01-01 00:00:00
abstract::Leucine is known to enhance insulin secretion from islets of Langerhans, and insulin promotes leucine uptake in peripheral tissues. The present studies were designed to elucidate the effects of leucine on glucose responsiveness and stimulus secretion coupling in mouse islets of Langerhans. The effects of 20 mM leucine...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-199103000-00015
更新日期:1991-03-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to clarify the clinical and pathophysiological characteristics of autoimmune pancreatitis (AIP) and its subtypes (lymphoplasmacytic sclerosing pancreatitis [LPSP] and idiopathic duct-centric pancreatitis [IDCP]) seen around the world. METHODS:An international multicenter surve...
journal_title:Pancreas
pub_type: 杂志文章,多中心研究
doi:10.1097/MPA.0b013e3182258a15
更新日期:2011-08-01 00:00:00
abstract:OBJECTIVES:To determine if RNA collected from pancreatic tissue, without the use of RNAlater, is useful for RNA sequencing (RNA-seq) despite degradation, and if so, then, via RNA-seq analysis, how does gene expression vary between pancreatitis etiologies. METHODS:Data were assessed in 2 dimensions, based on RNA-seq si...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/MPA.0000000000001607
更新日期:2020-09-01 00:00:00
abstract:OBJECTIVE:The transcription factor Stat1 is a member of the family of signal transducers and transcription activators and responds to interferon-γ stimulation. p21 is a p53-responsive gene for cell cycle regulation and mediates Stat1 antitumor activity. The aim of this study was to analyze their expression for predicti...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/MPA.0000000000000074
更新日期:2014-05-01 00:00:00
abstract:BACKGROUND:Psychological distress is highly prevalent in patients with pancreatic cancer (PC), yet little is known about the pathophysiology underlying the relationship between these 2 diseases. Our aim was to systematically review the evidence examining the pathophysiological mechanisms of the association between PC a...
journal_title:Pancreas
pub_type: 杂志文章,评审
doi:10.1097/MPA.0000000000001016
更新日期:2018-04-01 00:00:00
abstract::Tumor necrosis factor-alpha (TNF alpha) has been implicated as one of the numerous likely mediators of the systemic complications of acute pancreatitis. Recent suggestions that calcium (Ca2+) acts as a signal not only for TNF alpha release but also for TNF alpha action at distant sites led us to hypothesize that the c...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-199607000-00003
更新日期:1996-07-01 00:00:00