Abstract:
:Male genital tract birth defects have been associated in previous studies with several prenatal exposures to environmental and dietary risk factors. The purpose of this study was to explore the association between hypospadias and cryptorchidism, and the dietary habits of an agricultural population in Italy. A population-based case-control study was conducted in the Sicilian Province of Ragusa. Cases (n = 90) and controls (n = 202) included births for the period 1998-2002. Data on dietary habits of the mothers, as well as health-related social, occupational and environmental exposures prior to and during the index birth, were collected through interviews. Adjusted odds ratios (OR) were calculated by logistic regression after adjustment for confounding variables. Increased ORs were observed for mothers of children with hypospadias who, during pregnancy, frequently consumed fish (OR = 2.33 [95% confidence interval (CI) 1.03, 5.31]) and market-purchased fruit (OR = 5.10 [95% CI 1.31, 19.82]). For cryptorchidism, increased risk was observed in mothers consuming liver (OR = 5.21 [95% CI 1.26, 21.50]), and smoked products (OR = 2.46 [95% CI 1.15, 5.29]). For the two malformations pooled together, increased risk was associated with maternal consumption of liver (OR = 4.38 [95% CI 1.34, 14.26]) and with frequent consumption of wine (OR = 1.98 [95% CI 1.01, 3.86]). This study suggests that some maternal dietary factors may play a role in the development of congenital defects of the male reproductive tract. In particular, our data indicate that further research may be warranted on the endocrine-disrupting effects resulting from the bioaccumulation of contaminants (fish, liver), pesticides (marketed fruit, wine) and/or potentially toxic food components (smoked products, wine, liver).
journal_name
Paediatr Perinat Epidemioljournal_title
Paediatric and perinatal epidemiologyauthors
Giordano F,Carbone P,Nori F,Mantovani A,Taruscio D,Figà-Talamanca Idoi
10.1111/j.1365-3016.2007.00918.xsubject
Has Abstractpub_date
2008-05-01 00:00:00pages
249-60issue
3eissn
0269-5022issn
1365-3016pii
PPE918journal_volume
22pub_type
杂志文章abstract::There is conflicting evidence concerning the relationship between breast feeding and wheezing illness. The objective of this study was to investigate whether there is any association between breast feeding and wheezing in children aged over 5 years and to discover possible sources of heterogeneity. An electronic searc...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章,meta分析,评审
doi:10.1111/j.1365-3016.2011.01233.x
更新日期:2011-11-01 00:00:00
abstract::It is not clear to what extent ethnic differences in the term birthweight distribution are constitutional or pathological. This study explored term birthweight heterogeneity between ethnic groups and the explanatory role of constitutional and environmental factors. As part of a prospective cohort study, the Amsterdam ...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/j.1365-3016.2008.00945.x
更新日期:2008-07-01 00:00:00
abstract::We have developed a methodology for comparing the seasonal influences on two outcomes, when those influences may act cumulatively or instantaneously. We have used this to compare the seasonal pattern of intrauterine growth retardation (IUGR, as reflected by weight-for-gestational-age) and preterm delivery (as assessed...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/j.1365-3016.2006.00714.x
更新日期:2006-05-01 00:00:00
abstract:BACKGROUND:Recent data suggest that early-term births are associated with later respiratory morbidity (LRTI), and post-term births may decrease this risk. OBJECTIVES:The objective was to determine the impact of early-term, late-term, and post-term birth on hospital admission for LRTI up to the age of seven years. Addi...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/ppe.12631
更新日期:2020-03-01 00:00:00
abstract::To help fulfil the objectives of prospective studies of pregnancy and human development, such as the National Children's Study, there is a need to pinpoint ovulation and conception in a cohort of women. This paper discusses the suitability of using natural and easily observed markers of ovulation for detection of the ...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/j.1365-3016.2006.00767.x
更新日期:2006-11-01 00:00:00
abstract::This study examines the correlation and agreement between the calculated 'gestational interval' from the date of last menstrual period (LMP) and the Ballard newborn assessment of gestational maturity. It then investigates selected maternal socio-demographic, prenatal, intrapartum and infant factors which may account f...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/j.1365-3016.1990.tb00628.x
更新日期:1990-04-01 00:00:00
abstract:BACKGROUND:Obesity, a body mass index (BMI) ≥30 kg/m2 , is linked to infertility, potentially through a greater risk of anovulation due to elevated androgens. Yet, previous studies have not directly assessed the impact of adiposity, or body fat, on anovulation in the absence of clinical infertility. OBJECTIVE:To chara...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/ppe.12726
更新日期:2020-10-26 00:00:00
abstract:BACKGROUND:Previous studies of the association between tobacco smoke and hearing loss in children are limited, involve small samples and are cross-sectional. We investigated the association of maternal smoking during pregnancy and exposure to tobacco smoke at age 4 months with hearing impairment at age 3 years in child...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/ppe.12477
更新日期:2018-09-01 00:00:00
abstract::Group B streptococcal (GBS) infection is still an important cause of morbidity and mortality in newborn infants. In The Netherlands, there are no published data on the incidence of neonatal GBS infection. We collected data of all infants with GBS disease during the first 3 months of life, as reported to the Dutch Paed...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1046/j.1365-3016.2002.00437.x
更新日期:2002-10-01 00:00:00
abstract:BACKGROUND:Labour induction and caesarean are increasingly done without clinical indication. However, little is known about the prevalence of such interventions, or the characteristics of women who receive them. We used the 2003 revision of the US birth certificates to summarise recorded interventions and to characteri...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/ppe.12068
更新日期:2013-09-01 00:00:00
abstract:BACKGROUND:Prepregnancy cardiometabolic risk factors are associated with increased risks of adverse pregnancy outcomes. Neighbourhood features may reflect prepregnancy exposures that contribute to poor cardiometabolic health before pregnancy and may contribute to racial disparities in pregnancy outcomes. METHODS:Early...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/ppe.12531
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Although previous studies evaluated the association of maternal health parameters with neonatal adiposity, little is known regarding the complexity of the relationships among different maternal health parameters throughout pregnancy and its impact on neonatal adiposity. OBJECTIVES:To evaluate the direct and...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/ppe.12682
更新日期:2021-01-01 00:00:00
abstract::The study, aiming to document the effect of continued support for mothers on frequency of exclusive breast feeding, was carried out by inclusion of breast feeding counselling in the context of well-baby care. One hundred and forty-six mothers who had been exposed to two educational sessions on breast feeding after del...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/j.1365-3016.1991.tb00714.x
更新日期:1991-07-01 00:00:00
abstract::Infectious disease histories were evaluated in a population-based case-control study of childhood acute lymphoblastic leukaemia (ALL) as it has been hypothesised that delays in early infections are associated with an increased risk of disease. Allergy histories were also assessed as part of a broader evaluation of the...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/j.1365-3016.2005.00634.x
更新日期:2005-03-01 00:00:00
abstract:BACKGROUND:An association between education and preterm delivery has been observed in populations across Europe, but differences in methodology limit comparability. We performed a direct cross-cohort comparison of educational disparities in preterm delivery based on individual-level birth cohort data. METHODS:The stud...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/ppe.12185
更新日期:2015-05-01 00:00:00
abstract:BACKGROUND:Pregnant women treated with methadone as opioid maintenance therapy are more likely than women treated with buprenorphine to deliver preterm. Preterm birth is associated with less risk of neonatal abstinence syndrome (NAS). We sought to assess the role of preterm birth as a mediator of the relationship betwe...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/ppe.12443
更新日期:2018-03-01 00:00:00
abstract::There is still much debate as to the pathways through which some children develop asthma and others do not. One possible mechanism outlined here concerns the way in which stress may influence the neuroendocrine system and thence the immune system. Supporting evidence from animal experiments suggests that maternal pren...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/j.1365-3016.2007.00879.x
更新日期:2007-11-01 00:00:00
abstract:BACKGROUND:Preterm delivery may affect the development of the upper airways resulting in a higher risk of obstructive sleep apnoea (OSA). We investigated whether children born at early term (37-38 6/7 weeks' gestation) are at an increased risk for childhood OSA as compared with those born later. METHODS:In this popula...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/ppe.12342
更新日期:2017-03-01 00:00:00
abstract::Perinatal deaths were systematically investigated over a 25-month period in a Zimbabwean district and were classified into pathological subgroups according to Wigglesworth. There were 319 perinatal deaths (a rate of 30.6 per 1000) including 83 normally formed macerated stillbirths, 28 cases of congenital malformation,...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/j.1365-3016.1989.tb00380.x
更新日期:1989-07-01 00:00:00
abstract:BACKGROUND:Including twins in randomised trials leads to non-independence or clustering in the data. Clustering has important implications for sample size calculations, yet few trials take this into account. Estimates of the intracluster correlation coefficient (ICC), or the correlation between outcomes of twins, are n...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/ppe.12471
更新日期:2018-07-01 00:00:00
abstract::Despite nearly four million deliveries in the United States each year, minimal information exists on unintended health consequences following childbirth, particularly in relation to delivery method. The purpose of this study was to assess the association between method of delivery and the general health status, sexual...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1046/j.1365-3016.2001.00345.x
更新日期:2001-07-01 00:00:00
abstract::The fetal growth curve and neonatal mortality rate, based on gestational age and birthweight, are important for identifying groups of high-risk neonates and developing appropriate medical services and health-care programmes. The purpose of this study was to develop a national fetal growth curve for neonates in Korea, ...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/j.1365-3016.2007.00850.x
更新日期:2007-09-01 00:00:00
abstract::The aim of this paper is to estimate the infant mortality rate and the incidence of sudden infant death syndrome (SIDS) in Lombardy, Northern Italy, in the period 1990-2000 and to provide basic information for a subsequent comparison of the SIDS incidence before and after the risk-intervention campaign. A retrospectiv...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/j.1365-3016.2004.00583.x
更新日期:2004-09-01 00:00:00
abstract::Sudden infant death syndrome (SIDS) accounts for the largest number of deaths during the first year of life in developed countries. The possible causes of SIDS are numerous and, to date, there is no adequate unifying pathological explanation for SIDS. Epidemiological studies have played a key role in identifying risk ...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章,评审
doi:10.1046/j.1365-3016.2001.00330.x
更新日期:2001-04-01 00:00:00
abstract:BACKGROUND:While there is evidence of an association between caesarean birth and increased asthma in children in high-income countries, it is unknown whether this association exists in low-to-middle-income countries (LMICs). We investigated whether children born through caesarean in India and Vietnam are at increased r...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/ppe.12324
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Limited evidence exists on the association between exposure to Helicobacter pylori infection early in life, including fetal life, and neurodevelopment in childhood. METHODS:We used prospective data on 352 mother-child pairs and cross-sectional data on 674 children to assess the association of maternal and c...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/ppe.12374
更新日期:2017-07-01 00:00:00
abstract::Singleton survivors born to multigravidae in the whole island of Jamaica in 2 months (September-October 1986) were compared with singleton perinatal deaths occurring to multigravidae throughout the island in the 12-month period September 1986 to August 1987. Past obstetric history was obtained from the mothers using a...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/j.1365-3016.1994.tb00490.x
更新日期:1994-04-01 00:00:00
abstract::The nutritional status of a woman before and during pregnancy is important for a healthy pregnancy outcome. Maternal malnutrition is a key contributor to poor fetal growth, low birthweight (LBW) and short- and long-term infant morbidity and mortality. This review summarised the evidence on association of maternal nutr...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章,评审
doi:10.1111/j.1365-3016.2012.01308.x
更新日期:2012-07-01 00:00:00
abstract::Cognitively delayed children are at risk for poor mental and physical health throughout their lives. The economically disadvantaged and some race/ethnic groups are more likely to experience cognitive delay, but the age at which delays first emerge and the underlying mechanisms responsible for disparities are not well ...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/j.1365-3016.2008.01006.x
更新日期:2009-05-01 00:00:00
abstract::To estimate maternal age effects on the rates of vaginal birth after caesarean delivery (VBAC), the related maternal complications and patient election to attempt VBAC, we conducted a secondary analysis of a retrospective cohort study of women who were offered VBAC from 1996 to 2000 in 17 community and university hosp...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1365-3016.2007.00794.x
更新日期:2007-03-01 00:00:00