Abstract:
:Infectious disease histories were evaluated in a population-based case-control study of childhood acute lymphoblastic leukaemia (ALL) as it has been hypothesised that delays in early infections are associated with an increased risk of disease. Allergy histories were also assessed as part of a broader evaluation of the role of immune factors in ALL. Cases (n = 255) were diagnosed between 1980 and 1991 at one of four referral centres in a 31-county area of New York State; controls (n = 760) were a random sample of live births from the same region, frequency matched to cases by sex, race and birth year. Data were collected by mailed questionnaire, completed by case and control parents in 1995. Allergy and infectious histories before the age at leukaemia diagnosis for cases and an equivalent age for controls were evaluated. The adjusted odds ratio and 95% confidence interval [CI] associated with a positive history of any allergy was 0.58 [95% CI 0.38, 0.88] compared with a negative allergy history. The occurrence of several common childhood illnesses before 25 months of age and ALL were assessed, with both weak positive and weak inverse associations observed. Overall, these analyses provide little support for the hypothesis that infection delay in early life is associated with an increased risk of ALL. Children with positive allergy histories reported significantly more infections than those with negative histories; however, effect modification of the infection-ALL associations by child allergy history was not observed. Nonetheless, these observations suggest the importance of assessing both allergy and infectious histories and their possible interactions when evaluating the association between these immune factors and childhood ALL.
journal_name
Paediatr Perinat Epidemioljournal_title
Paediatric and perinatal epidemiologyauthors
Rosenbaum PF,Buck GM,Brecher MLdoi
10.1111/j.1365-3016.2005.00634.xsubject
Has Abstractpub_date
2005-03-01 00:00:00pages
152-64issue
2eissn
0269-5022issn
1365-3016pii
PPE634journal_volume
19pub_type
杂志文章abstract::Although race and preterm delivery are known to be associated with sudden infant death syndrome (SIDS), the relationships between age at death from SIDS and these factors have not been well described. To examine these relationships, we used linked infant birth and death records for the cohort of 1,204,375 White and 28...
journal_title:Paediatric and perinatal epidemiology
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doi:10.1111/j.1365-3016.1990.tb00655.x
更新日期:1990-07-01 00:00:00
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journal_title:Paediatric and perinatal epidemiology
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doi:10.1046/j.1365-3016.1997.d01-19.x
更新日期:1997-04-01 00:00:00
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pub_type: 杂志文章,多中心研究
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journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章,评审
doi:10.1111/j.1365-3016.1990.tb00657.x
更新日期:1990-07-01 00:00:00
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journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1046/j.1365-3016.1999.00215.x
更新日期:1999-10-01 00:00:00
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journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/ppe.12517
更新日期:2018-11-01 00:00:00
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journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章,评审
doi:10.1111/j.1365-3016.1989.tb00369.x
更新日期:1989-01-01 00:00:00
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journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/ppe.12342
更新日期:2017-03-01 00:00:00
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journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章,多中心研究
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更新日期:2006-09-01 00:00:00
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doi:10.1111/ppe.12077
更新日期:2013-11-01 00:00:00
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pub_type: 杂志文章
doi:10.1046/j.1365-3016.2002.00425.x
更新日期:2002-07-01 00:00:00
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journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/j.1365-3016.2008.01006.x
更新日期:2009-05-01 00:00:00
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journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1046/j.1365-3016.2001.00317.x
更新日期:2001-01-01 00:00:00
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journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/j.1365-3016.2008.01009.x
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journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章,评审
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journal_title:Paediatric and perinatal epidemiology
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pub_type: 杂志文章
doi:10.1111/j.1365-3016.1989.tb00380.x
更新日期:1989-07-01 00:00:00
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journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/j.1365-3016.2006.00703.x
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abstract::A nested case-control study of cryptorchidism (i.e. undescended testicles) was undertaken as part of a hospital-based cohort study of 6699 singleton male neonates in New York City. Since some of the cryptorchid infants experienced spontaneous descent of their testes, separate analysis was performed for this third grou...
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doi:10.1111/j.1365-3016.1996.tb00024.x
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journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/ppe.12002
更新日期:2012-11-01 00:00:00
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pub_type: 杂志文章
doi:10.1111/ppe.12618
更新日期:2020-09-01 00:00:00
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journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章,多中心研究
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更新日期:2004-01-01 00:00:00
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pub_type: 杂志文章
doi:10.1111/ppe.12507
更新日期:2019-01-01 00:00:00
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journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1046/j.1365-3016.2000.00228.x
更新日期:2000-01-01 00:00:00
abstract::Maternal smoking during pregnancy is associated with increased risk of childhood overweight body mass index (BMI). Less is known about the association between prenatal secondhand tobacco smoke (SHS) exposure and childhood BMI. We followed 292 mother-child dyads from early pregnancy to 3 years of age. Prenatal tobacco ...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/j.1365-3016.2010.01146.x
更新日期:2010-11-01 00:00:00