Abstract:
BACKGROUND:While there is evidence of an association between caesarean birth and increased asthma in children in high-income countries, it is unknown whether this association exists in low-to-middle-income countries (LMICs). We investigated whether children born through caesarean in India and Vietnam are at increased risk of caregiver-reported asthma by 8 years of age. METHODS:Data from an ongoing multi-national longitudinal cohort study (the Young Lives Study) in two LMICs (India n = 2026; Vietnam n = 2000) were used. Caregiver questionnaires captured information on caregiver-reported long-term respiratory problems such as asthma or wheeze at age 8 years, birth mode and a range of sociodemographic factors. Multivariable logistic regression models using propensity score adjustment were used to explore birth mode and asthma at age 8 years adjusted for a range of known confounders. RESULTS:Children delivered by caesarean in India (odds ratio (OR) 2.6, 95% confidence interval (CI) 1.3, 5.4) and Vietnam (OR 2.0, 95% CI 1.2, 3.3) had greater odds of asthma at age 8 years, after adjustment for other risk factors including wealth, liveborn parity, low birthweight, geographic location, cooking fuel used, livestock ownership, household size, housing quality and parental smoking. CONCLUSIONS:The study suggests that caesarean birth may be associated with an increased risk of childhood asthma in India and Vietnam. The underlying mechanisms of this finding need to be further elucidated.
journal_name
Paediatr Perinat Epidemioljournal_title
Paediatric and perinatal epidemiologyauthors
Lavin T,Franklin P,Preen DBdoi
10.1111/ppe.12324subject
Has Abstractpub_date
2017-01-01 00:00:00pages
47-54issue
1eissn
0269-5022issn
1365-3016journal_volume
31pub_type
杂志文章abstract::Clarke et al. suggested that women who have had a spontaneous abortion are at an increased risk in their next pregnancy of producing an offspring with a neural tube defect (NTD). A matched case-control study was carried out to test the related hypothesis that a spontaneous abortion occurring in the 6-month period prio...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/j.1365-3016.1993.tb00391.x
更新日期:1993-04-01 00:00:00
abstract::There has been a trend over the past two decades in some Western countries for women to delay childbearing, a factor associated with an increased risk of perinatal mortality (stillbirth and neonatal death). While the rates of stillbirth and neonatal mortality have improved in some countries, it has not been establishe...
journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
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journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章,多中心研究
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更新日期:2015-11-01 00:00:00
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journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/ppe.12026
更新日期:2013-03-01 00:00:00
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journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/j.1365-3016.2005.00673.x
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journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/j.1365-3016.2005.00655.x
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journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/j.1365-3016.2011.01242.x
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journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/ppe.12289
更新日期:2016-07-01 00:00:00
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journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
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journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章,评审
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journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/ppe.12714
更新日期:2020-11-06 00:00:00
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journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/j.1365-3016.1991.tb00699.x
更新日期:1991-04-01 00:00:00
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journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/j.1365-3016.2010.01188.x
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journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/j.1365-3016.1989.tb00531.x
更新日期:1989-10-01 00:00:00
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journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/j.1365-3016.2007.00850.x
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journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/ppe.12185
更新日期:2015-05-01 00:00:00
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journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/j.1365-3016.1991.tb00727.x
更新日期:1991-10-01 00:00:00
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journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/j.1365-3016.1995.tb00148.x
更新日期:1995-07-01 00:00:00
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journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
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journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/j.1365-3016.2007.00879.x
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pub_type: 杂志文章
doi:10.1111/ppe.12471
更新日期:2018-07-01 00:00:00
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journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
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journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/j.1365-3016.1993.tb00599.x
更新日期:1993-01-01 00:00:00
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journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章,多中心研究
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更新日期:1999-01-01 00:00:00
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journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
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更新日期:2016-07-01 00:00:00
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journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章,多中心研究
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更新日期:1996-07-01 00:00:00
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journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/ppe.12331
更新日期:2017-01-01 00:00:00
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journal_title:Paediatric and perinatal epidemiology
pub_type: 杂志文章
doi:10.1111/j.1365-3016.2005.00613.x
更新日期:2005-01-01 00:00:00